Forschungsdatenbank PMU-SQQUID

PMU-Autor/inn/en

Abstract

We investigated the relationship between serum triglyceride level and acute ischemic stroke severity using infarct volume on CT brain scans as a marker. A total of 121 consecutive acute ischemic stroke patients (53 males and 68 females, age 47-93 years) with anterior circulation (75%), posterior circulation (9%) or lacunar infarcts (16%) were examined. All patients were admitted within 24 h of the symptom onset, and CT scans were taken over the subsequent 24-72 h. With adjustment for the infarct type, age, sex, timing of CT imaging (24-36, >36-48 or >48-72 h since admission), atrial fibrillation, hypertension, fasting cholesterol and glucose levels, a higher (> or =1.70 mmol/l) fasting serum triglyceride level (within 24 h after admission) was associated with a lower infarct volume (p = 0.014). In line with a recent report on milder clinical symptoms in acute ischemic stroke patients with higher triglycerides, the results suggest an independent association between serum triglyceride level and stroke severity.

Useful keywords (using NLM MeSH Indexing)

Aged

Aged, 80 and over

Blood Glucose/metabolism

Brain Infarction/blood*

Brain Infarction/radiography*

Cholesterol/blood

Female

Humans

Image Interpretation, Computer-Assisted*

Infarction, Anterior Cerebral Artery/blood*

Infarction, Anterior Cerebral Artery/radiography*

Infarction, Posterior Cerebral Artery/blood*

Infarction, Posterior Cerebral Artery/radiography*

Male

Mathematical Computing

Middle Aged

Prognosis

Risk Factors

Tomography, X-Ray Computed*

Triglycerides/blood*

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