PMU-Autor/inn/en
Augat PeterAbstract
Thus far, orthopedic research lacks a suitable animal model of osteoporosis. In OVX sheep, 6 months of steroid exposure reduced bone density and mechanical competence. Bone properties and bone formation did not recover for another 6 months. Therefore, steroid-treated OVX sheep may serve as a large animal model for osteopenic bone.
Useful keywords (using NLM MeSH Indexing)
Animals
Bone Density/drug effects*
Bone Density/physiology
Bone and Bones/anatomy*
histology*
Bone and Bones/drug effects*
Bone and Bones/physiology
Female
Femur/anatomy*
histology
Femur/drug effects
Femur/physiology
Glucocorticoids/pharmacology*
Glucocorticoids/therapeutic use
Models, Animal
Osteoporosis/drug therapy
Ovariectomy
Sheep
Spine/anatomy*
histology
Spine/drug effects
Spine/physiology
Tibia/anatomy*
histology
Tibia/drug effects
Tibia/physiology
Find related publications in this database (Keywords)
osteoporosis