Forschungsdatenbank PMU-SQQUID

Neurofilament heavy chain as a marker of neuroaxonal pathology and prognosis in acute encephalitis.
Sellner, J; Davies, NW; Howard, RS; Petzold, A;
Eur J Neurol. 2014; 21(6):845-850
Originalarbeiten (Zeitschrift)

Abstract/Keywords Web of Science PubMed Full Text

PMU-Autor/inn/en

Sellner Johann

Abstract

The neurological outcome of acute encephalitis can be devastating and early prognosis remains difficult. Biomarkers that quantify the extent of early brain injury are needed to improve the prognostic accuracy and aid patient management. Our objective was to assess whether cerebrospinal fluid (CSF) protein biomarkers of neuroaxonal and glial cell injury are elevated in distinct forms of acute encephalitis and predictive of poor outcome.

Useful keywords (using NLM MeSH Indexing)

Adult

Aged

Aged, 80 and over

Biomarkers/cerebrospinal fluid

Encephalitis/cerebrospinal fluid*

Encephalitis/pathology

Female

Glasgow Outcome Scale

Humans

Male

Middle Aged

Neurofilament Proteins/cerebrospinal fluid*

Prognosis

Prospective Studies

S100 Calcium Binding Protein beta Subunit/cerebrospinal fluid

Severity of Illness Index

Young Adult

Find related publications in this database (Keywords)

biomarker
encephalitis
neuroaxonal injury
neurofilament
prognosis