BRACHTL GABRIELE
- former member of the university
Publications
108 Publications
2022
Journal Articles
Evaluating a Targeted Cancer Therapy Approach Mediated by RNA trans-Splicing In Vitro and in a Xenograft Model for Epidermolysis Bullosa-Associated Skin Cancer
Woess, K; Sun, Y; Morio, H; Stierschneider, A; Kaufmann, A; Hainzl, S; Trattner, L; Kocher, T; Tockner, B; Leb-Reichl, V; Steiner, M; Brachtl, G; South, AP; Bauer, JW; Reichelt, J; Furihata, T; Wally, V; Koller, U; Piñón Hofbauer, J; Guttmann-Gruber, C;
Int J Mol Sci. 2022; 23(1):
Full papers/articles (Journal)
A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation.
Wolf, M; Poupardin, RW; Ebner-Peking, P; Andrade, AC; Blöchl, C; Obermayer, A; Gomes, FG; Vari, B; Maeding, N; Eminger, E; Binder, HM; Raninger, AM; Hochmann, S; Brachtl, G; Spittler, A; Heuser, T; Ofir, R; Huber, CG; Aberman, Z; Schallmoser, K; Volk, HD; Strunk, D;
J Extracell Vesicles. 2022; 11(4): e12207
Full papers/articles (Journal)
2021
Journal Articles
Improving Human Induced Pluripotent Stem Cell-Derived Megakaryocyte Differentiation and Platelet Production.
Krisch, L; Brachtl, G; Hochmann, S; Andrade, AC; Oeller, M; Ebner-Peking, P; Schallmoser, K; Strunk, D;
Int J Mol Sci. 2021; 22(15):
Full papers/articles (Journal)
Leveraging immune memory against measles virus as an antitumor strategy in a preclinical model of aggressive squamous cell carcinoma.
Leb-Reichl, VM; Kienzl, M; Kaufmann, A; Stoecklinger, A; Tockner, B; Kitzmueller, S; Zaborsky, N; Steiner, M; Brachtl, G; Trattner, L; Kreideweiss, P; Reinsch, C; Panzner, S; Greil, R; Strunk, D; Bauer, JW; Gratz, IK; Guttmann-Gruber, C; Hofbauer, JP
J IMMUNOTHER CANCER. 2021; 9(10):
Full papers/articles (Journal)
Unpublished conference presentations
AML-derived extracellular vesicles convey immunomodulatory potential.
Binder, HM; Maeding, N; Vári, B; Raninger, A; Wolf, M; Heuser, T; Obermayr, A; Brachtl, G; Schallmoser, K; Strunk, D
Paracelsus Virtual Science Get Together 2021 – 2. Virtual Science Summer ; 01.07.-01.10.2021; online. 2021.
„AML-derived extracellular vesicles convey immunomodulatory potential.”
Binder, HM; Maeding, N; Vári, B; Raninger, A; Wolf, M; Heuser, T; Obermayr, A; Brachtl, G; Schallmoser, K; Strunk, D;
4th GSEV 2021 Autumn Meeting; 03.-04.10.2021; Freiburg im Breisgau. 2021.
Mesoderm induction improves human induced pluripotent stem cell-derived megakaryocyte differentiation and platelet production.
Krisch, L; Brachtl, G; Hochmann, S; Cronemberger A; Ebner-Peking, P; Öller, M; Schallmoser, K; Strunk, D
Paracelsus Virtual Science Get Together 2021 – 2. Virtual Science Summer ; 01.07.-01.10.2021; online. 2021.
Enhanced angiogenesis and wound healing in vivo induced by extracellular vesicles from therapeutic grade allogeneic human placental stromal cells.
Martin Wolf, Rodolphe Poupardin, Constantin Blöchl, Andre Cronemberger Andrade, Fausto Gueths Gomes, Patrica Peking , Balazs Vari, Essi Eminger; Heide-Marie Binder, Anna M Raninger, Gabi Brachtl, Andreas Spittler, Thomas Heuser, Astrid Obermayer, Christian G Huber, Katharina Schallmoser, Hans-Dieter Volk, Dirk Strunk
10th Annual Meeting ISEV 2021; 18.-21.05.2021; online. 2021.
First evidence for a protein corona around extracellular vesicles playing an essential role in aiding angiogenesis and skin regeneration.
Martin Wolf, Rodolphe W Poupardin, Patricia Ebner-Peking, André Cronemberger Andrade, Constantin Blöchl, Astrid Obermayer, Fausto Gueths Gomes,, Balazs Vari, Essi Eminger, Heide-Marie Binder, Anna M Raninger, Sarah Hochmann, Gabriele Brachtl, Andreas Spittler, Thomas Heuser, Racheli Ofir, Christian G Huber, Zami Aberman, Katharina Schallmoser, Hans-Dieter Volk, Dirk Strunk
ASEV Young Scientist Meeting 2021; 15.-16.10.2021; Krems. 2021.
Essential role of a protein corona around extracellular vesicles in aiding angiogenesis and skin regeneration.
Martin Wolf, Rodolphe W Poupardin, Patricia Ebner-Peking, André Cronemberger Andrade, Constantin Blöchl, Astrid Obermayer, Fausto Gueths Gomes,, Balazs Vari, Essi Eminger, Heide-Marie Binder, Anna M Raninger, Sarah Hochmann, Gabriele Brachtl, Andreas Spittler, Thomas Heuser, Racheli Ofir, Christian G Huber, Zami Aberman, Katharina Schallmoser, Hans-Dieter Volk, Dirk Strunk
GSEV Meeting 2021; 03.-04.10.2021; Freiburg. 2021.
2020
Journal Articles
Effect of Glycine on BV-2 Microglial Cells Treated with Interferon-γ and Lipopolysaccharide.
Egger, F; Jakab, M; Fuchs, J; Oberascher, K; Brachtl, G; Ritter, M; Kerschbaum, HH; Gaisberger, M;
Int J Mol Sci. 2020; 21(3):
Full papers/articles (Journal)
2019
Journal Articles
Human CD4
Klicznik, MM; Morawski, PA; Höllbacher, B; Varkhande, SR; Motley, SJ; Kuri-Cervantes, L; Goodwin, E; Rosenblum, MD; Long, SA; Brachtl, G; Duhen, T; Betts, MR; Campbell, DJ; Gratz, IK;
Sci Immunol. 2019; 4(37):
Full papers/articles (Journal)
Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination.
Rivera, FJ; de la Fuente, AG; Zhao, C; Silva, ME; Gonzalez, GA; Wodnar, R; Feichtner, M; Lange, S; Errea, O; Priglinger, E; OSullivan, A; Romanelli, P; Jadasz, JJ; Brachtl, G; Greil, R; Tempfer, H; Traweger, A; Bátiz, LF; Küry, P; Couillard-Despres, S; Franklin, RJM; Aigner, L;
Glia. 2019; 67(8):1510-1525
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Proteomic analysis reveals angiogenic and immunomodulatory function for placental stromal cell-derived extracellular vesicles
Wolf, M; Vari, V; Blochl, C; Raninger, AM; Poupardin, R; Eminger, E; Brachtl, G; Oeller, M; Hochreiter, A; Binder, HM; Obermaier, A; Heuser, T; Spittler, A; Seifert, M; Huber, CG; Schallmoser, K; Ofir, R; Aberman, Z; Volk, HD; Strunk, D
HUM GENE THER. 2019; 30(11): A139-A139.
Abstracts (Journal)
Unpublished conference presentations
Batch effect of stromal cell culture conditions prevail donor variation and culture duration effects at the transcriptome and epigenome level.
Brachtl, G; Poupardin, R; Raninger, A; Hoog, A; Schallmoser, K; Jürchott, K; Volk, H-D; Strunk, D;
SCI-TReCS Retreat 2019; 16.-17.09.2019; Wagrain. 2019.
How to select the appropriate cell sorting strategy.
Hoog, A; Raninger, AM; Peking, P; Brachtl, G; Strunk D;
SCI-TReCS Retreat 2019; 16.-17.09.2019; Wagrain. 2019.
No identical stromal cells: Transcriptomic meta-Analysis Highlights differences between bone marrow-derived mesenchymal stromal/progenitor cells and other stromal cell sources.
Poupardin, R; Kalathur, RK; Brachtl, G; Jeevan-Raj, BP; Scharler, C; Schallmoser, K; Strunk, D
5th International CCS-Workshop and 15th International CLL-Workshop; 05.-06.04.2019; Fuschl am See. 2019.
A standardized in vitro potency assay allows identifying the immunomodulation potential of independent cell types and extracellular vesicles.
Raninger, A; Ketterl, N; Brachtl, G; Hoog, A; Pachler, K; Oeller, M; Scharler, C; Wolf, M; Vári, B; Binder, H-M; Schallmoser, K; Strunk, D;
SCI-TReCS Retreat 2019; 16.-17.09.2019; Wagrain. 2019.
Stepwise maturation of human iPSC into clonogenic immunosuppressive mesodermal stromal progenitors identified extra-hematopoietic immunomodulatory role of DOCK proteins.
Scharler, C; Ketterl, N; Poupardin, R; Jürchott, K; Wolf, M; Hoog, A; Raninger AM; Brachtl, G; Daheron, L; Schallmoser, K; Stachelscheid, H; Volk, H-D; Strunk, D;
7th Annual GSCN Conference; 23.-25.09.2019; Berlin. 2019.
Stepwise maturation of human iPSC into clonogenic immunosuppressive mesodermal stromal progenitors identified extra-hematopoietic immunomodulatory role of DOCK proteins.
Scharler, C; Ketterl, N; Poupardin, R; Jürchott, K; Wolf, M; Hoog, A; Raninger AM; Brachtl, G; Daheron, L; Schallmoser, K; Stachelscheid, H; Volk, H-D; Strunk, D;
Poster SCI-TReCS Retreat 2019; 16.-17.09.2019; Wagrain. 2019.
Stepwise maturation of human iPSC into clonogenic immunosuppressive mesodermal stromal progenitors identified extra-hematopoietic immunomodulatory role of DOCK proteins.
Scharler, C; Ketterl, N; Poupardin, R; Jürchott, K; Wolf, M; Hoog, A; Raninger AM; Brachtl, G; Daheron, L; Schallmoser, K; Stachelscheid, H; Volk, HD; Strunk, D
RESTORE 1st Advanced Therapies Science Meeting; 25.-26.11.2019; Berlin. 2019.
AML-derived extracellular vesicles convey immunomodulatory potential.
Vári, B; Binder, HM; Raninger, A; Wolf, M; Girgis R; Heuser, T; Mayr, C; Brachtl, G; Schallmoser, K; Strunk, D
ESGCT 27th Annual Congress; 22.-25.10.2019; Barcelona. 2019.
AML-derived extracellular vesicles convey immunomodulatory potential.
Vári, B; Binder, HM; Raninger, A; Wolf, M; Girgis R; Heuser, T; Mayr, C; Brachtl, G; Schallmoser, K; Strunk, D;
7th Annual GSCN Conference; 23.-25.09.2019; Berlin. 2019.
AML-derived extracellular vesicles convey immunomodulatory potential.
Vári, B; Binder, HM; Raninger, A; Wolf, M; Girgis R; Heuser, T; Mayr, C; Brachtl, G; Schallmoser, K; Strunk, D;
GSEV & ASEV Autumn Meeting; 28.-29.11.2019; Freising-Weihenstephan. 2019.
AML-derived extracellular vesicles convey immunomodulatory potential.
Vári, B; Binder, HM; Raninger, A; Wolf, M; Girgis R; Heuser, T; Mayr, C; Brachtl, G; Schallmoser, K; Strunk, D;
SCI-TReCS Retreat 2019; 16.-17.09.2019; Wagrain. 2019.
Instruction of the bone marrow niche by leukemic cells.
Vári, B; Raninger, A; Wolf, M; Brachtl, G; Binder, H-M; Girgis, R; Obermayer, A; Mayr, C; Schallmoser, K; Strunk, D
5th International CCS Workshop and 15th International CLL Workshop; 05.-06.04.2019; Fuschl am See. 2019.
Proteomic analysis reveals angiogenic and immunomodulatory function for placental stromal cell-derived extracellular vesicles.
Wolf, M; Vári, B; Blöchl, C; Raninger, AM; Poupardin, R; Beez, CM; Hoog, A; Brachtl, G; Eminger, E; Oeller, M; Spittler, A; Heuser, T; Obermayer, A; Seifert, M; Huber, CG; Schallmoser, K; Ofir, R; Aberman, Z; Volk, H-D; Strunk D;
7th Annual GSCN Conference; 23.-25.09.2019; Berlin. 2019.
Proteomic analysis reveals angiogenic and immunomodulatory function for placental stromal cell-derived extracellular vesicles.
Wolf, M; Vári, B; Blöchl, C; Raninger, AM; Poupardin, R; Beez, CM; Hoog, A; Brachtl, G; Eminger, E; Oeller, M; Spittler, A; Heuser, T; Obermayer, A; Seifert, M; Huber, CG; Schallmoser, K; Ofir, R; Aberman, Z; Volk, H-D; Strunk D;
SCI-TReCS Retreat 2019; 16.-17.09.2019; Wagrain. 2019.
Biology & Function of Stromal Cell-derived EVs.
Wolf, M; Vári, B; Blöchl, C; Raninger, AM; Poupardin, R; Beez, CM; Hoog, A; Brachtl, G; Eminger, E; Oeller, M; Spittler, A; Heuser, T; Obermayer, A; Seifert, M; Huber, CG; Schallmoser, K; Ofir, R; Aberman, Z; Volk, HD; Strunk, D
SCI-TReCS Retreat 2019; 16.-17.09.2019; Wagrain. 2019.
Proteomic analysis reveals angiogenic and immunomodulatory function for placental stromal cell-derived extracellular vesicles.
Wolf, M; Vári, B; Blöchl, C; Raninger, AM; Poupardin, R; Beez, CM; Hoog, A; Brachtl, G; Eminger, E; Oeller, M; Spittler, A; Heuser, T; Obermayer, A; Seifert, M; Huber, CG; Schallmoser, K; Ofir, R; Aberman, Z; Volk, HD; Strunk D
ESGCT 27th Annual Congress; 22.-25.10.2019; Barcelona. 2019.
Proteomic analysis reveals angiogenic and immunomodulatory function for placental stromal cell-derived extracellular vesicles.
Wolf, M; Vári, B; Blöchl, C; Raninger, AM; Poupardin, R; Beez, CM; Hoog, A; Brachtl, G; Eminger, E; Oeller, M; Spittler, A; Heuser, T; Obermayer, A; Seifert, M; Huber, CG; Schallmoser, K; Ofir, R; Aberman, Z; Volk, HD; Strunk D
RESTORE 1st Advanced Therapies Science Meeting; 25.-26.11.2019; Berlin. 2019.
Proteomic analysis reveals angiogenic and immunomodulatory function for placental stromal cell-derived extracellular vesicles.
Wolf, M; Vári, B; Blöchl, C; Raninger, AM; Poupardin, R; Beez, CM; Hoog, A; Brachtl, G; Eminger, E; Oeller, M; Spittler, A; Heuser, T; Obermayer, A; Seifert, M; Huber, CG; Schallmoser, K; Ofir, R; Aberman, Z; Volk, HD; Strunk D;
GSEV & ASEV Autumn Meeting; 28.-29.11.2019; Freising-Weihenstephan. 2019.
2018
Journal Articles
Selection of Tissue Factor-Deficient Cell Transplants as a Novel Strategy for Improving Hemocompatibility of Human Bone Marrow Stromal Cells
Oeller, M; Laner-Plamberger, S; Hochmann, S; Ketterl, N; Feichtner, M; Brachtl, G; Hochreiter, A; Scharler, C; Bieler, L; Romanelli, P; Couillard-Despres, S; Russe, E; Schallmoser, K; Strunk, D
THERANOSTICS. 2018; 8(5): 1421-1434.
Full papers/articles (Journal)
Effects of linagliptin on endothelial function and postprandial lipids in coronary artery disease patients with early diabetes: a randomized, placebo-controlled, double-blind trial.
Tripolt, NJ; Aberer, F; Riedl, R; Url, J; Dimsity, G; Meinitzer, A; Stojakovic, T; Aziz, F; Hödl, R; Brachtl, G; Strunk, D; Brodmann, M; Hafner, F; Sourij, H;
Cardiovasc Diabetol. 2018; 17(1): 71
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Influence of Heparin on Gene Expression of Stromal Cells Derived from Different Tissues
Laner-Plamberger, S; Oeller, M; Kalathur, R; Poupardin, R; Hochmann, S; Brachtl, G; Pachler, K; Kreutzer, C; Strunk, D; Rohde, E; Schallmoser, K
TRANSFUSION. 2018; 58: 66A-67A.
Abstracts (Journal)
Plasma Rotational Thrombelastometry for Evaluation of Hemocompatibility of Human Umbilical Cord Derived Stromal Cells
Oeller,M, Laner-Plamberger, S; Brachtl, G; Rohde, E; Strunk, D; Schallmoser, K;
Transfusion. 2018; 58: 68A-69A.-AABB Annual Meeting; 13.-16.10.2018; Boston.
Abstracts (Journal)
Generation of immunosuppressive iPSC-derived stromal cells for tissue regeneration
Scharler, C; Peking, P; Ketterl, N; Hochreiter, A; Juerchott, K; Brachtl, G; Wimmer, M; Hochmann, S; Wolf, M; Schallmoser, K; Volk, HD; Strunk, D
HUM GENE THER. 2018; 29(12): A56-A56.
Abstracts (Journal)
Unpublished conference presentations
Towards better understanding of extracellular vesicle-mediated stroma-leukemia crosstalk in the bone marrow niche.
Girgis, R; Raninger, A; Hochreiter, A; Obermayer, A; Schallmoser, K; Brachtl, G; Wolf, M; Strunk, D
SCI-TReCS Retreat 2018; 13.-14.09.2018; Wagrain. 2018.
NO IDENTICAL STROMAL CELLS: HUMAN STROMAL PROGENITORS FROM
NON-SKELETAL SOURCES DISPLAY LIMITED CHONDROGENIC POTENTIAL.
Hochmann, S; Scharler, C; Textor, M; Mittermeir, M; Brachtl, G; Föttinger, P; Hochreiter, A; Schmidt-Bleek, K; Ellinghaus, A; Geissler, S; Duda, G; Strunk, D
SCI-TReCS Retreat 2018; 13.-14.09.2018; Wagrain. 2018.
Development of immunosuppressive iPSC-derived stromal cells for tissue regeneration.
Peking, P; Scharler, C; Ketterl, N; Hochreiter, A; Jürchott, K; Höfler, M; Brachtl, G; Wimmer, M; Wolf, M; Hochmann, S; Schallmoser, K; Volk, H-D; Strunk, D
6th Annual GSCN Conference; 19.-21.09.2018; Heidelberg. 2018.
NO IDENTICAL STROMAL CELLS: TRANSCRIPTOMIC META-ANALYSIS HIGHLIGHTS
DIFFERENCES BETWEEN BONE-MARROW-DERIVED MESENCHYMAL
STROMAL/PROGENITOR CELLS AND OTHER STROMAL CELL SOURCES.
Poupardin, R; Kalathur, RK; Brachtl, G; Jeevan-Raj, BP; Scharler, C; Schallmoser, K; Strunk, D
6th Annual GSCN Conference; 19.-21.09.2018; Heidelberg. 2018.
NO IDENTICAL STROMAL CELLS: TRANSCRIPTOMIC META-ANALYSIS HIGHLIGHTS DIFFERENCES BETWEEN BONE-MARROW-DERIVED MESENCHYMAL STROMAL/PROGENITOR CELLS AND OTHER STROMAL CELL SOURCES.
Poupardin, R; Kalathur, RK; Brachtl, G; Jeevan-Raj, BP; Scharler, C; Schallmoser, K; Strunk, D
SCI-TReCS Retreat 2018; 13.-14.09.2018; Wagrain. 2018.
2017
Journal Articles
An RNA-targeted therapy for dystrophic epidermolysis bullosa.
Peking, P; Koller, U; Duarte, B; Murillas, R; Wolf, S; Maetzig, T; Rothe, M; Kocher, T; García, M; Brachtl, G; Schambach, A; Larcher, F; Reichelt, J; Bauer, JW; Murauer, EM;
Nucleic Acids Res. 2017; 45(17): 1025-10269.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Regenerative potential of periosteum-derived stromal cells
Brachtl, G; Hochreiter, A; Hochmann, S; Mittermeir, M;
Raninger, A; Schallmoser, K; Wittig, J; Gaggl, A; Strunk, D
Human Gene Therapy. 2017; 28: A89-A90.-25th Anniversary Congress of the ESGCT; 17.-20.10.2017; Berlin.
Abstracts (Journal)
No identical stromal cells: Human stromal progenitors from
non-skeletal sources display limited chondrogenic potential.
Hochmann, S; Scharler, C; Textor, M; Mittermeir, M;
Brachtl, G; Föttinger, P; Hochreiter, A; Schmidt-Bleek, K;
Ellinghaus, A; Geissler, S; Duda, G; Strunk, D
Human Gene Therapy. 2017; 28: A84-A84.-25th Anniversary Congress of the ESGCT; 17.-20.10.2017; Berlin.
Abstracts (Journal)
Human Platelet Lysate Modifications Affect Mesenchymal Stromal Cell Biology Depending on Cell Origin
Laner-Plamberger, S; Öller, M; Brachtl, G; Strunk, D; Hartl, A; Pachler, K; Feichtner, M; Hauser-Kronberger, C; Wiedemann, H; Rohde, E; Schallmoser, K
Vox Sanguinis. 2017; 112(1):285-286.-27th Regional Congress of the International Society of Blood Transfusion; 17.06.-21.06.2017; Copenhagen.
Abstracts (Journal)
Viral antigen-specific pre-vaccination prevents engraftment of tumor cells expressing the cognate antigen in mice
Leb-Reichl, V; Kienzl, M; Stoecklinger, A; Kitzmueller, S; Gratz, IK; Brachtl, G; Zaborsky, N; Reichelt, J; Gruber, C; Hofbauer, JP
J INVEST DERMATOL. 2017; 137(10): S286-S286.
Abstracts (Journal)
Hemocompatibility of stromal cells depends on tissue factor expression and is influenced by organ origin and culture conditions
Oeller, M; Laner-Plamberger, S; Feichtner, M; Brachtl, G; Dunai, ZA; Russe, E; Rohde, E; Strunk, D; Schallmoser, K
TRANSFUS MED HEMOTH. 2017; 44: 74-74.
Abstracts (Journal)
Selection of tissue factor-deficient bone marrow stromal cell
transplants as a novel strategy to improve therapeutic
applicability
Oeller, M; Laner-Plamberger, S; Ketterl, N; Feichtner, M; Raninger, A; Hochreiter, A; Brachtl, G; Dunai, ZA; Russe, E; Schulte, M; Rohde, E; Schallmoser, K; Strunk, D
Human Gene Therapy. 2017; 28: A97-A98.-25th Anniversary Congress of the ESGCT; 17.-20.10.2017; Berlin.
Abstracts (Journal)
Tissue Factor Expression and Hemocompatibility of Stromal Cells Depend on Organ Origin and Culture Conditions
Öller, M; Laner-Plamberger, S; Feichtner, M; Brachtl, G; Dunai, Z; Russe, E; Rohde, E; Strunk, D; Schallmoser, K
Vox Sanguinis. 2017; 112(1):65-66.-27th Regional Congress of the International Society of Blood Transfusion; 17.06.-21.06.2017; Copenhagen.
Abstracts (Journal)
Hemocompatibility of stromal cells depends on tissue factor expression and is influenced by organ origin and culture
Öller, M; Laner-Plamberger, S; Feichtner, M; Brachtl, G; Dunai, ZA; Russe, E; Rohde, E; Strunk, D; Schallmoser, K
Transfusion Medicine and Hemotherapy. 2017; 44(Suppl.1):p.74--50.Jahrestagung der DGTI; 24.-27.10.2017; Köln.
Abstracts (Journal)
Stepwise maturation of human iPSC into clonogenic
immunosuppressive mesodermal stromal progenitors
identifies key immunomodulatory pathways.
Scharler, C; Ketterl, N; Jürchott, K; Brachtl, G; Schallmoser, K; Volk, HD; Strunk, D
Human Gene Therapy. 2017; 28: A83-A84.-25th Anniversary Congress of the ESGCT; 17.-20.10.2017; Berlin.
Abstracts (Journal)
Unpublished conference presentations
Human mesenchymal progenitors from non-skeletal adult sources display limited chondrogenic Differentiation.
Hochmann, S; Scharler, C; Textor, M; Mittermeir, M; Brachtl, G; Föttinger, P; Hochreiter, A; Geissler, S; Strunk, D
ISSCR Annual Meeting; 14.-17.06.2017; Boston. 2017.
No Identical Stromal Cells: Human Stromal Progenitors from Non-Skeletal Sources Display Limited Chondrogenic Potential
Hochmann, S; Scharler, C; Textor, M; Mittermeir, M; Brachtl, G; Föttinger, P; Hochreiter, A; Schmidt-Bleek, K; Ellinghaus, A; Geissler, S; Duda, G; Strunk, D
25th Anniversary Congress of the ESGCT; 17.-20.10.2017; Berlin. 2017.
Regenerative potential of periosteum-derived stromal cells.
Hochreiter, A; Brachtl, G; Hochmann, S; Mittermeir, M; Raninger, A; Schallmoser, K; Wittig, J; Gaggl, A; Strunk, D
SCI-TReCS Retreat 2017; 11.-12.09.2017; Seeon. 2017.
Long term reproducibility of an animal serum-free potency assay monitoring immune modulation capacity of human mesenchymal stem/progenitor cells (MSPCs).
Ketterl, N; Scharler, C; Brachtl, G; Raninger, A; Hochreiter, A; Schallmoser, K; Strunk D;
SCI-TReCS Retreat 2017; 11.-12.09.2017; Seeon. 2017.
Selection of tissue factor-deficient bone marrow stromal cell transplants as a novel strategy to improve therapeutic applicability
Öller, M; Laner-Plamberger, S; Ketterl, N; Feichtner, M; Raninger, A; Hochreiter, A; Brachtl, G; Dunai, ZA; Russe, E; Schulte, M; Rohde, E; Schallmoser, K; Strunk D
25th Anniversary Congress of the ESGCT; 17.-20.10.2017; Berlin. 2017.
Stepwise maturation of human iPSC into clonogenic immunosuppressive mesodermal stromal progenitors identifies key immunomodulatory pathways
Scharler, C; Ketterl, N; Jürchott, K; Brachtl, G; Schallmoser, K; Volk, HD; Strunk, D
25th Anniversary Congress of the ESGCT; 17.-20.10.2017; Berlin. 2017.
Heart regeneration by iPSC-derivced organoids.
Scharler, C; Ketterl, N; Jürchott, K; Brachtl, G; Schallmoser, K; Volk, HD; Strunk D
SCI-TReCS Retreat 2017; 11.-12.09.2017; Seeon. 2017.
2016
Journal Articles
A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study.
Rawstron, AC; Fazi, C; Agathangelidis, A; Villamor, N; Letestu, R; Nomdedeu, J; Palacio, C; Stehlikova, O; Kreuzer, KA; Liptrot, S; O"Brien, D; de Tute, RM; Marinov, I; Hauwel, M; Spacek, M; Dobber, J; Kater, AP; Gambell, P; Soosapilla, A; Lozanski, G; Brachtl, G; Lin, K; Boysen, J; Hanson, C; Jorgensen, JL; Stetler-Stevenson, M; Yuan, C; Broome, HE; Rassenti, L; Craig, F; Delgado, J; Moreno, C; Bosch, F; Egle, A; Doubek, M; Pospisilova, S; Mulligan, S; Westerman, D; Sanders, CM; Emerson, R; Robins, HS; Kirsch, I; Shanafelt, T; Pettitt, A; Kipps, TJ; Wierda, WG; Cymbalista, F; Hallek, M; Hillmen, P; Montserrat, E; Ghia, P;
Leukemia. 2016; 30(4):929-936
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Leukotriene receptor inhibition mobilizes human stem cells in vivo
Brachtl, G; Hochreiter, A; Jacobs, VR; Schafer, R; Strunk, D
HUM GENE THER. 2016; 27(11): A56-A56.
Abstracts (Journal)
Understanding the molecular landscape of human bone marrow-derived mesenchymal stem/progenitor cells through meta-analysis
Kalathur, RK; Brachtl, G; Jeevan-Raj, BP; Scharler, C; Reinisch, A; Schallmoser, K; Strunk, D
HUM GENE THER. 2016; 27(11): A65-A65.
Abstracts (Journal)
Introducing an animal serum-free potency assay to monitor immune modulation capacity of human mesenchymal stem/progenitor cells (MSPCs)
Ketterl, N; Brachtl, G; Scharler, C; Schallmoser, K; Reinisch, A; Strunk, D
HUM GENE THER. 2016; 27(11): A64-A65.
Abstracts (Journal)
Influence of heparin on the genomic profile of human mesenchymal stromal/progenitor cells
Laner-Plamberger, S; Oller, M; Kalathur, R; Brachtl, G; Strunk, D; Feichtner, M; Hauser-Kronberger, C; Schallmoser, K; Rohde, E
HUM GENE THER. 2016; 27(11): A61-A61.
Abstracts (Journal)
Efficient expansion of mesenchymal stem/progenitor cells supported by fibrinogen-depleted pooled human platelet lysate
Oller, M; Laner-Plamberger, S; Feichtner, M; Dunai, ZA; Raninger, A; Gimona, M; Hartl, A; Hauser-Kronberger, C; Russe, E; Bieback, K; Rohde, E; Brachtl, G; Scharler, C; Strunk, D; Schallmoser, K
HUM GENE THER. 2016; 27(11): A63-A64.
Abstracts (Journal)
Fibrinogen-Depleted Pooled Human Platelet Lysate for Efficient Expansion of Mesenchymal Stromal Cells
Öller, M; Laner-Plamberger, S; Feichtner, M; Dunai, ZA; Raninger, A; Gimona, M; Hartl, A; Hauser-Kronberger, C; Russe, E; Bieback, K; Rohde, E; Brachtl, G; Scharler, C; Strunk, D; Schallmoser, K
Vox Sanguinis. 2016; 111(Suppl. 1):285--34th International Congress of the ISBT ; 03.-08.09.2016; Dubai.
Abstracts (Journal)
Efficient Expansion of Mesenchymal Stromal Cells by Fibrinogen-Depleted Pooled Human Platelet Lysate
Öller, M; Laner-Plamberger, S; Feichtner, M; Dunai, ZA; Raninger, A; Gimona, M; Hartl, A; Hauser-Kronberger, C; Russe, E; Bieback, K; Rohde, E; Brachtl, G; Scharler, C; Strunk, D; Schallmoser, K
Transfusion Medicine and Hemotherapy. 2016; 43(Suppl.1):71--49. Jahrestagung der Deutschen Gesellschaft für Transfusionsmedizin und Immunhämatologie ; 07.-10.09.2016; Nürnberg.
Abstracts (Journal)
Stepwise maturation of human iPS cells into clonogenic immunosuppressive mesenchymal stem/progenitor cells
Scharler, C; Ketterl, N; Hofler, M; Brachtl, G; Schallmoser, K; Strunk, D
HUM GENE THER. 2016; 27(11): A64-A64.
Abstracts (Journal)
Unpublished conference presentations
Leukotriene receptor inhibition mobilizes human stem cells in vivo.
Brachtl, G; Hochreiter, A; Jacobs, VR; Schäfer, R; Strunk, D
4th Annual Meeting of the German Stem Cell Network (GSCN); 12.-14.09.2016; Hannover. 2016.
Leukotriene receptor inhibition mobilizes human stem cells in vivo.
Brachtl, G; Hochreiter, A; Jacobs, VR; Schäfer, R; Strunk, D
ESGCT and ISSCR Collaborative Congress; 18.-21.10.2016; Florenz. 2016.
Leukotriene receptor inhibition mobilizes human stem cells in vivo.
Brachtl, G; Hochreiter, A; Schäfer, R; Strunk, D
3rd PACT-Symposium: Designer Cells Go Clinic; 23.-24.09.2016; Wien. 2016.
Effect of different cell culture conditions on the growth and clonogenicity of MSPCs.
Brachtl, G; Raninger, A; Hochreiter, A; Schäfer, R; Schallmoser, K; Strunk, D
3rd Research Conference of the Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS); 27.10.2016; Salzburg. 2016.
Effect of different cell culture conditions on the growth and clonogenicity of MSPCs.
Brachtl, G; Raninger, A; Hochreiter, A; Schäfer, R; Schallmoser, K; Strunk, D
PMU Science Day; 24.06.2016; Salzburg. 2016.
Rolle von Mesenchymalen Stammzellen in der Organregeneration & Immunmodulation.
Brachtl, G; Strunk, D
20. Jahressymposium der IGLD; 25.-27.02.2016; Hamburg. 2016.
MSPCs from non-skeletal adult sources have an altered chondrogenic regeneration potency.
Hochmann, S; Scharler, C; Textor, M; Brachtl, G; Föttinger, P; Hochreiter, A; Geissler, S; Strunk, D
3rd Research Conference of the Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS); 27.10.2016; Salzburg. 2016.
Understanding the molecular landscape of human bone marrow-derived mesenchymal stem/progenitor cells through meta-analysis.
Kalathur, RK; Brachtl, G; Jeevan-Raj, BP; Scharler, C; Reinisch, A; Schallmoser, K; Strunk, D
4th Annual Meeting of the German Stem Cell Network (GSCN); 12.-14.09.2016; Hannover. 2016.
Understanding the molecular landscape of human bone marrow-derived mesenchymal stem/progenitor cells through meta-analysis.
Kalathur, RK; Brachtl, G; Jeevan-Raj, BP; Scharler, C; Reinisch, A; Schallmoser, K; Strunk, D
ESGCT and ISSCR Collaborative Congress; 18.-21.10.2016; Florenz. 2016.
Understanding the molecular landscape of human BM-derived MSPCs through meta-analysis.
Kalathur, RK; Brachtl, G; Jeevan-Raj, BP; Scharler, C; Reinisch, A; Schallmoser, K; Strunk, D
3rd Research Conference of the Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS); 27.10.2016; Salzburg. 2016.
Introducing an animal serum-free potency assay to monitor immune modulation capacity of human mesenchymal stem/progenitor cells (MSPCs).
Ketterl, N; Brachtl, G; Scharler, C; Schallmoser, K; Reinisch, A; Strunk, D
PMU Science Day; 24.06.2016; Salzburg. 2016.
Introducing an animal serum-free potency assay to monitor immune modulation capacity of human mesenchymal stem/progenitor cells (MSPCs).
Ketterl, N; Brachtl, G; Scharler, C; Schallmoser, K; Reinisch, A; Strunk, D
ESGCT and ISSCR Collaborative Congress; 18.-21.10.2016; Florenz. 2016.
Stepwise maturation of human iPS cells into immunosuppressive mesenchymal stem/progenitor cells.
Scharler, C; Ketterl, N; Höfler, M; Brachtl, G; Schallmoser, K; Strunk, D
4th Annual Meeting of the German Stem Cell Network (GSCN); 12.-14.09.2016; Hannover. 2016.
Stepwise maturation of human iPS cells into immunosuppressive mesenchymal stem/progenitor cells.
Scharler, C; Ketterl, N; Höfler, M; Brachtl, G; Schallmoser, K; Strunk, D
3rd Research Conference of the Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS); 27.10.2016; Salzburg. 2016.
Stepwise maturation of human iPS cells into immunosuppressive mesenchymal stem/progenitor cells.
Scharler, C; Ketterl, N; Höfler, M; Daheron, L; Brachtl, G; Schallmoser, K; Strunk, D
ESGCT and ISSCR Collaborative Congress; 18.-21.10.2016; Florenz. 2016.
Stepwise maturation of human iPS cells into immunosuppressive mesenchymal stem/progenitor cells.
Scharler, C; Ketterl, N; Höfler, M; Daheron, L; Brachtl, G; Schallmoser, K; Strunk, D
3rd PACT-Symposium: Designer Cells Go Clinic; 23.-24.09.2016; Wien. 2016.
2015
Journal Articles
CXCL12-induced VLA-4 activation is impaired in trisomy 12 chronic lymphocytic leukemia cells: a role for CCL21.
Ganghammer, S; Hutterer, E; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, PW; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Kruschinski, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, TN;
Oncotarget. 2015; 6(14):12048-12060
Full papers/articles (Journal)
A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance.
Ketterl, N; Brachtl, G; Schuh, C; Bieback, K; Schallmoser, K; Reinisch, A; Strunk, D;
Stem Cell Res Ther. 2015; 6: 236
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
A fluorescence-based screening system accelerates the design of RNA trans-splicing molecules for mRNA repair.
Kocher, T; Koller, U; Seyr, J; Hainzl, S; Mayer, E; Brachtl, G; Lener, T; Bauer, J; Wally, V; Murauer, E
J INVEST DERMATOL. 2015; 135: S60-S60.
Abstracts (Journal)
Unpublished conference presentations
Does Montelukast mobilize human stem/progenitor cells in vivo?.
Brachtl, G; Hochreiter, A; Strunk, D
2nd Research Conference of the Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS); 05.11.2015; Salzburg. 2015.
Introducing an animal serum-free potency assay to monitor immune modulation capacity of human mesenchymal stem/progenitor cells (MSPCs).
Ketterl, N; Brachtl, G; Schuh, C; Schallmoser, K; Strunk, D
3rd International Annual Conference of the German Stem Cell Network (GSCN); 09.-11.09.2015; Frankfurt. 2015.
Introducing an animal serum-free potency assay to monitor immune modulation capacity of human mesenchymal stem/progenitor cells (MSPCs).
Ketterl, N; Brachtl, G; Schuh, C; Schallmoser, K; Strunk, D
2nd Research Conference of the Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS); 05.11.2015; Salzburg. 2015.
Introducing an animal serum-free potency assay to monitor immune modulation capacity of human mesenchymal stem/progenitor cells (MSPCs).
Ketterl, N; Brachtl, G; Schuh, C; Schallmoser, K; Strunk, D
World Conference on Regenerative Medicine 2015; 21.-23.10.2015; Leipzig. 2015.
Optimizing conditions to differentiate human iPS cells into functional mesenchymal stem/progenitor cells.
Schuh, C; Ketterl, N; Höfler, M; Brachtl, G; Schallmoser, K; Strunk, D
3rd International Annual Conference of the German Stem Cell Network (GSCN); 09.-11.09.2015; Frankfurt. 2015.
Optimizing conditions to differentiate human iPS cells into functional mesenchymal stem/progenitor cells.
Schuh, C; Ketterl, N; Höfler, M; Brachtl, G; Schallmoser, K; Strunk D.
World Conference on Regenerative Medicine 2015; 21.-23.10.2015; Leipzig. 2015.
2014
Journal Articles
The pathogenic relevance of the prognostic markers CD38 and CD49d in chronic lymphocytic leukemia.
Brachtl, G; Piñón Hofbauer, J; Greil, R; Hartmann, TN;
Ann Hematol. 2014; 93(3): 361-374.
Reviews
Conference papers, proceedings, abstracts
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner
Hutterer, E; Ganghammer, S; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, P; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, T
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner. 2014; 79(6): 424-478.-Scandinavian Society for Immunology
42nd Annual Meeting; 11.-14.06.2014; Reykjavik.
Abstracts (Journal)
Bing Neel syndrome mimicking Lyme neuroborreliosis
Kalss, G; Trinka, E; Himmer, M; Brachtl, G; Muehlmann, J
EUR J NEUROL. 2014; 21: 619-619.
Abstracts (Journal)
Unpublished conference presentations
U-derived stem/progenitor cells: A noninvasice cell source for regenerative purposes.
Brachtl, G; Schuh, C; Ketterl, N; Höfler, M; Strunk, D
1st Research Conference of the Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS); 13.11.2014; Salzburg. 2014.
U-derived stem/progenitor cells: A noninvasice cell source for regenerative purposes.
Brachtl, G; Schuh, C; Ketterl, N; Höfler, M; Strunk, D
2nd International Annual Conference of the German Stem Cell Network (GSCN); 03.-05.11.2014; Heidelberg. 2014.
Optimizing conditions to differentiate human induced pluripotent stem cells into mesenchymal stem/progenitor cells.
Höfler, M; Schuh, C; Ketterl, N; Brachtl, G; Strunk, D
International Annual Conference of the German Stem Cell Network (GSCN); 03.-05.11.2014; Heidelberg. 2014.
Analyzing the immune modulation potential of human mesenchymal stem/progenitor cells.
Ketterl, N; Brachtl, G; Schuh, C; Schallmoser, K; Strunk, D
1st Research Conference of the Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS); 13.11.2014; Salzburg. 2014. ; 13.11.2014; Salzburg. 2014.
Predicting and optimizing the immune modulation potential of human mesenchymal stem/progenitor cells.
Ketterl, N; Brachtl, G, Schuh, C; Schallmoser, K; Strunk, D
2nd International Annual Conference of the German Stem Cell Network (GSCN); 03.-05.11.2014; Heidelberg. 2014.
Optimizing conditions to differentiate human iPS cells into functional mesenchymal stem/progenitor cells.
Schuh, C; Höfler, M; Ketterl, N; Brachtl, G; Strunk, D
1st Research Conference of the Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS); 13.11.2014; Salzburg. 2014.
2011
Journal Articles
Differential bone marrow homing capacity of VLA-4 and CD38 high expressing chronic lymphocytic leukemia cells.
Brachtl, G; Sahakyan, K; Denk, U; Girbl, T; Alinger, B; Hofbauer, SW; Neureiter, D; Hofbauer, JP; Egle, A; Greil, R; Hartmann, TN;
PLoS One. 2011; 6(8):e23758
Full papers/articles (Journal)
2010
Journal Articles
Modifying akt signaling in B-cell chronic lymphocytic leukemia cells.
Hofbauer, SW; Piñón, JD; Brachtl, G; Haginger, L; Wang, W; Jöhrer, K; Tinhofer, I; Hartmann, TN; Greil, R;
Cancer Res. 2010; 70(18):7336-7344
Full papers/articles (Journal)
2009
Journal Articles
Circulating B-cell chronic lymphocytic leukemia cells display impaired migration to lymph nodes and bone marrow.
Hartmann, TN; Grabovsky, V; Wang, W; Desch, P; Rubenzer, G; Wollner, S; Binsky, I; Vallon-Eberhard, A; Sapoznikov, A; Burger, M; Shachar, I; Haran, M; Honczarenko, M; Greil, R; Alon, R;
Cancer Res. 2009; 69(7):3121-3130
Full papers/articles (Journal)
Difference in the relative distribution of CD4+ T-cell subsets in B-CLL with mutated and unmutated immunoglobulin (Ig) VH genes: implication for the course of disease.
Tinhofer, I; Weiss, L; Gassner, F; Rubenzer, G; Holler, C; Greil, R;
J Immunother. 2009; 32(3):302-309
Full papers/articles (Journal)
2006
Journal Articles
Expression levels of CD38 in T cells predict course of disease in male patients with B-chronic lymphocytic leukemia.
Tinhofer, I; Rubenzer, G; Holler, C; Hofstaetter, E; Stoecher, M; Egle, A; Steurer, M; Greil, R;
Blood. 2006; 108(9):2950-2956
Full papers/articles (Journal)
2005
Conference papers, proceedings, abstracts
Expression levels of CD38 in tumor cells and T-cells are of prognostic value in B-CLL
Tinhofer, I; Rubenzer, G; Egle, A; Greil, R
BLOOD. 2005; 106(11): 347A-347A.
Abstracts (Journal)