COUILLARD-DESPRÉS SÉBASTIEN
Institute of Experimental Neuroregeneration
Spinal Cord Injury and Tissue Regeneration Center Salzburg
Publications
|
Researcher Profile
269 Publications
2023
Journal Articles
Depolarization and Hyperexcitability of Cortical Motor Neurons after Spinal Cord Injury Associates with Reduced HCN Channel Activity.
Benedetti, B; Bieler, L; Erhardt-Kreutzer, C; Jakubecova, D; Benedetti, A; Reisinger, M; Dannehl, D; Thome, C; Engelhardt, M; Couillard-Despres, S;
Int J Mol Sci. 2023; 24(5):
Full papers/articles (Journal)
Case-matched radiological and clinical outcome evaluation of interlaminar versus microsurgical decompression of lumbar spinal stenosis.
Saravi, B; Ülkümen, S; Lang, G; Couillard-Després, S; Hassel, F;
Eur Spine J. 2023;
Full papers/articles (Journal)
Metabolic fingerprinting of different Sideritis taxa infusions and their neurogenic activity.
Tomou, EM; Bieler, L; Spöttl, T; Couillard-Despres, S; Skaltsa, H; Urmann, C;
Planta Med. 2023;
Full papers/articles (Journal)
Semi-Synthesis of Different Pyranoflavonoid Backbones and the Neurogenic Potential.
Urmann, C; Bieler, L; Hackl, M; Chia-Leeson, O; Couillard-Despres, S; Riepl, H;
Molecules. 2023; 28(10):
Full papers/articles (Journal)
2022
Journal Articles
Effects of Extracorporeal Shockwave Therapy on Functional Recovery and Circulating miR-375 and miR-382-5p after Subacute and Chronic Spinal Cord Contusion Injury in Rats
Ashmwe, M; Posa, K; Ruhrnossl, A; Heinzel, JC; Heimel, P; Mock, M; Schadl, B; Keibl, C; Couillard-Despres, S; Redl, H; Mittermayr, R; Hercher, D
BIOMEDICINES. 2022; 10(7): 1630
Full papers/articles (Journal)
Why Would the Brain Need Dormant Neuronal Precursors?
Benedetti, B; Couillard-Despres, S;
Front Neurosci. 2022; 16: 877167
Full papers/articles (Journal)
Spinal Cord Injury and Loss of Cortical Inhibition
Benedetti, B; Weidenhammer, A; Reisinger, M; Couillard-Despres, S
INT J MOL SCI. 2022; 23(10): 5622
Reviews
Neuronal and Brain Maturation.
Bonfanti, L; Couillard-Despres, S
INT J MOL SCI. 2022; 23(8):
Editorials
Allergy-induced systemic inflammation impairs tendon quality.
Lehner, C; Spitzer, G; Langthaler, P; Jakubecova, D; Klein, B; Weissenbacher, N; Wagner, A; Gehwolf, R; Trinka, E; Iglseder, B; Paulweber, B; Aigner, L; Couillard-Després, S; Weiss, R; Tempfer, H; Traweger, A;
EBioMedicine. 2022; 75:103778
Full papers/articles (Journal)
Artificial Intelligence-Driven Prediction Modeling and Decision Making in Spine Surgery Using Hybrid Machine Learning Models.
Saravi, B; Hassel, F; Ulkumen, S; Zink, A; Shavlokhova, V; Couillard-Despres, S; Boeker, M; Obid, P; Lang, GM
J PERS MED. 2022; 12(4):
Reviews
Full-endoscopic versus conventional microsurgical therapy of lumbar disc herniation: a prospective, controlled, single-center, comprehensive cohort trial (FEMT-LDH trial)
Saravi, B; Ulkumen, S; Couillard-Despres, S; Hassel, F; Lang, GR
TRIALS. 2022; 23(1): 982
Full papers/articles (Journal)
One-Year Clinical Outcomes of Minimal-Invasive Dorsal Percutaneous Fixation of Thoracolumbar Spine Fractures
Saravi, B; Ulkumen, S; Couillard-Despres, S; Lang, G; Hassel, F
MEDICINA-LITHUANIA. 2022; 58(5): 606
Full papers/articles (Journal)
Performance of Artificial Intelligence-Based Algorithms to Predict Prolonged Length of Stay after Lumbar Decompression Surgery
Saravi, B; Zink, A; Ulkumen, S; Couillard-Despres, S; Hassel, F; Lang, G
J CLIN MED. 2022; 11(14): 4050
Full papers/articles (Journal)
On the Acceptance of "Fake" Histopathology: A Study on Frozen Sections Optimized with Deep Learning.
Siller, M; Stangassinger, LM; Kreutzer, C; Boor, P; Bulow, RD; Kraus, TJF; von Stillfried, S; Wolfl, S; Couillard-Despres, S; Oostingh, GJ; Hittmair, A; Gadermayr, M;
J Pathol Inform. 2022; 13: 6
Full papers/articles (Journal)
Evaluation of Multi-Scale Multiple Instance Learning to Improve Thyroid Cancer Classification
Tschuchnig, ME; Grubmuller, P; Stangassinger, LM; Kreutzer, C; Couillard-Despres, S; Oostingh, GJ; Hittmair, A; Gadermayr, M
INT CONF IMAG PROC. 2022;
Full papers/articles (Journal)
Unpublished conference presentations
Acute intralesional application of extracellular vesicles improves outcomes in a rat model of traumatic spinal cord injury.
Bieler, L; Romanelli, P; Heimel, P; Škokić, S; Jakubecova, D; Kreutzer, C; Zaunmair, P; Smolčić, T; Benedetti, B; Rohde, E; Gimona, M; Hercher, D; Dobrivojević Radmilović, M; Couillard-Despres, S
FENS Forum 2022
; 09.07. - 13.07.2022; Paris. 2022.
The slow awakening of dormant neuronal precursors in the aging brain
Bruno Benedetti, Maximilian Reisinger, Lara Bieler, Gabriele Gabriele, Dominika Jakubecova, Ariane Benedetti, Rodolphe Poupardin, Sébastien Couillard-Despres
Virtual Science Get Together Paracelsus Science Summer; 01.07.2023; Salzburg. 2022.
Sideritis – a traditionally used plant to fight neurodegenerative disease?
Fischill, H; Hettig, J; Tomou, EM; Skaltsa, H; Urmann, C;
Couillard-Després, S; Bieler, L
virtual Science get together 2022; 01.07.-30.09.2022; Online. 2022.
Stem cell-based regeneration of muscles
Grabner C, Benedetti A, Kreutzer C, Romanelli P, Thurner M, Couillard-Després S
EMBO workshop muscle formation, maintenance, regeneration and pathology; 24.-29.04.2022; Gouvieux. 2022.
Stem cell-based regeneration of muscles
Grabner C, Benedetti A, Kreutzer C, Romanelli P, Thurner M, Couillard-Després S
Virtual Science Get Together 2022; 01.07.-30.09.2022; Salzburg. 2022.
Slow maturation of dormant neuronal precursors in the aged mouse brain
Reisinger, M; Benedetti, B; Benedetti, A; Gabriele, G; Kreutzer, C; Poupardin, R; Couillard-Despres, S
FENS Forum 2022; 09.-13.07.2022; Paris. 2022.
Entzündung im Zaum halten: Extrazelluläre Vesikel zur akuten Behandlung des geschädigten Rückenmarks.
Sebastien Couillard-Despres
39. Arbeitstagung der Neurointensivmedizin (ANIM); 20.-22.01.2022; Digital. 2022.
Extracellular vesicles from mesenchymal stromal cells improve functional and structural outcomes after spinal cord injury in a rat model
Sebastien Couillard-Despres
15th International Neurotrauma Symposium; 17.-20.07.2022; Berlin. 2022.
2021
Journal Articles
Granulocyte colony-stimulating factor in traumatic spinal cord injury.
Aschauer-Wallner, S; Leis, S; Bogdahn, U; Johannesen, S; Couillard-Despres, S; Aigner, L
DRUG DISCOV TODAY. 2021; 26(7): 1642-1655.
Reviews
PSA Depletion Induces the Differentiation of Immature Neurons in the Piriform Cortex of Adult Mice.
Coviello, S; Benedetti, B; Jakubecova, D; Belles, M; Klimczak, P; Gramuntell, Y; Couillard-Despres, S; Nacher, J
INT J MOL SCI. 2021; 22(11):
Full papers/articles (Journal)
Involvement of Neuropeptide Galanin Receptors 2 and 3 in Learning, Memory and Anxiety in Aging Mice.
Locker, F; Bieler, L; Nowack, LMF; Leitner, J; Brunner, SM; Zaunmair, P; Kofler, B; Couillard-Despres, S
MOLECULES. 2021; 26(7):
Full papers/articles (Journal)
Myogenic progenitor cell transplantation for muscle regeneration following hindlimb ischemia and reperfusion.
Messner, F; Thurner, M; Muller, J; Blumer, M; Hofmann, J; Marksteiner, R; Couillard-Despres, S; Troppmair, J; Ofner, D; Schneeberger, S; Hautz, T
STEM CELL RES THER. 2021; 12(1): 146
Full papers/articles (Journal)
Enhancing Functional Recovery Through Intralesional Application of Extracellular Vesicles in a Rat Model of Traumatic Spinal Cord Injury.
Romanelli, P; Bieler, L; Heimel, P; Škokić, S; Jakubecova, D; Kreutzer, C; Zaunmair, P; Smolčić, T; Benedetti, B; Rohde, E; Gimona, M; Hercher, D; Dobrivojević Radmilović, M; Couillard-Despres, S;
Front Cell Neurosci. 2021; 15: 795008
Full papers/articles (Journal)
Combination of Defined CatWalk Gait Parameters for Predictive Locomotion Recovery in Experimental Spinal Cord Injury Rat Models.
Timotius, IK; Bieler, L; Couillard-Despres, S; Sandner, B; Garcia-Ovejero, D; Labombarda, F; Estrada, V; Müller, HW; Winkler, J; Klucken, J; Eskofier, B; Weidner, N; Puttagunta, R;
eNeuro. 2021; 8(2):
Full papers/articles (Journal)
Quantification of anomalies in rats spinal cords using autoencoders.
Tschuchnig, ME; Zillner, D; Romanelli, P; Hercher, D; Heimel, P; Oostingh, GJ; Couillard-Després, S; Gadermayr, M;
Comput Biol Med. 2021; 138: 104939
Full papers/articles (Journal)
Neuroregenerative Potential of Prenyl- and Pyranochalcones: A Structure-Activity Study.
Urmann, C; Bieler, L; Priglinger, E; Aigner, L; Couillard-Despres, S; Riepl, HM;
J Nat Prod. 2021; 84(10): 2675-2682.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
HCN channel activation and intrinsic excitability of motor neurons are affected by spinal cord injury
Bruno Benedetti, Lara Bieler, Christina Kreutzer, Dominika Jakubecova, Ariane Benedetti, Sebastien Couillard-Despres
HCN channel activation and intrinsic excitability of motor neurons are affected by spinal cord injury. 2021; -Neuroscience 2021 -SfN; 08-11.11.2021; Virtual.
Abstracts (Journal)
Hops-based Extract with Anti-oxidant Properties Shapes Neuroinflammation in Aged CNS
Silva, ME; Mansilla, J; Ehrenfeld, P; Simirgiotis, M; Sanchez, E; Hinrichsen, B; Krugmann, C; Bieler, L; Couillard-Despres, S; Aigner, L; Rivera, FJ
GLIA. 2021; 69: E455-E456.
Abstracts (Journal)
The Story of Xanthohumol C - a Promising Neuro-regenerative Chalcone from Hops
Urmann, C; Kirchinger, M; Bieler, L; Couillard-Despres, S; Riepl, H
PLANTA MED. 2021; 87(15): 1247-1247.
Abstracts (Journal)
Unpublished conference presentations
The effect of low-energy extracorporeal shockwave treatment on the functional, morphological and molecular level in sub-acute and chronic phases of traumatic SCI
Aschmwe, M; Posa-Markaryan, K; Rührnößl, A; Heimel, P; Heinzel, J; Mittermayr, R; Redl, H; Couillard-Despres, S; Bieler, L; Kreutzer, C; Hercher, D
17th Austrian Neuroscience Association Meeting ; 28.-30.09.2021; Salzburg. 2021.
HCN channels activation and intrinsic excitability of motor neurons are affected by spinal cord injury.
Benedetti, B; Bieler, L; Kreutzer, C; Jakubecova, D; Benedetti, A; Couillard-Despres, S
17th Austrian Neuroscience Association Meeting; 28.-30.09.2021; Salzburg. 2021.
Understanding the role of platelets in Alzheimer's disease
Bessa de Sousa, D; Unger, M; Mrowetz, H; Altendorfer, B; Benedetti, A; Poupardin, R; Fröhlich, T; Aigner, L; Kniewallner, K;
PMU Science Get Together; 02.07.-31.10.2021; virtuell. 2021.
Retro- and anterograde axonal tracing via injection of AAV particles to study neuroregeneration after spinal cord injury
Bieler, L; Jakubecova, D; Swann,V; Kreutzer, C; Couillard-Despres, S
Virtual PMU Science Get Together 2021; 02.07.- 31.10.2021 ; Virtual. 2021.
Extracellular vesicles to improve outcomes after traumatic spinal cord injury
Bieler, L; Romanelli, P; Heimel, P; Škokic, S; Jakubecova, D; Kreutzer, C; Zaunmair, P; Smolcic, T; Benedetti, B; Rohde, E; Gimona, M; Hercher, D; Dobrivojevic Radmilovic, M; Couillard-Despres, S
Meeting of the Austrian Cluster for Tissue Regeneration; 30.08.-01.09.2021; Vienna. 2021.
Intralesional administration of extracellular vesicles improves functional recovery in a rat model of traumatic spinal cord injury
Bieler, L; Romanelli, P; Heimel, P; Škokic, S; Jakubecova, D; Kreutzer, C; Zaunmair, P; Smolcic, T; Benedetti, B; Rohde, E; Gimona, M; Hercher, D; Dobrivojevic Radmilovic, M; Couillard-Despres, S
Austrian Neuroscience Association Meeting; 28.-30.09.2021; Salzburg. 2021.
Galanin receptors 2 and 3 modulate the inflammatory response following experimental traumatic brain injury
Brunner, SM; Gaisbauer, S; Yip, PK; Ramspacher, A; Leitner, J; Kreutzer, C; Pallier, PN; Bieler, L; Couillard-Despres, S; Kofler, B
17th Austrian Neuroscience Association Meeting; 28.-30.09.2021; Salzburg. 2021.
Reshaping neuronal input/output parameters in rat primary motor cortex after SCI
Bruno Benedetti, Dominik Dannehl, Christian Thome, Lara Bieler, Jan Maximilian Janssen, Johannes Roos, Corinna Corcelli, Christian Schultz, Maren Engelhardt, Sébastien Couillard-Després
Austrian Cluster for Tissue Regeneration ; 30-31.08.2021; Vienna. 2021.
Mechanisms of neuronal maturation in the adult and aging brain
Bruno Benedetti, Gabriele Gabriele, Maximilian Reisinger, Christina Kreutzer, Rodolphe Poupardin, Sébastien Couillard-Després
Axons 2021: structure and function; 04-07.11.2021; Virtual. 2021.
Mechanisms of neuronal maturation in the adult and aging brain
Bruno Benedetti, Gabriele Gabriele, Maximilian Reisinger, Christina Kreutzer, Rodolphe Poupardin, Sébastien Couillard-Després
PMU get together; 02.07.-31.10.2021; Virtual. 2021.
HCN channel activation and intrinsic excitability of motor neurons are affected by spinal cord injury
Bruno Benedetti, Lara Bieler, Christina Kreutzer, Dominika Jakubecova, Ariane Benedetti, Sebastien Couillard-Despres
Neuroscience 2021; 08-11.11.2021; Virtual. 2021.
Stem cell-based regeneration of muscles
Grabner C, Benedetti A, Kreutzer C, Romanelli P, Thurner M, Couillard-Després S
Virtual Science Get Together 2021; 02.07.-31.10.2021; Nürnberg. 2021.
Long-term intranasal application of alarin is safe with no effects on food intake and body weight
Huber, S; Brunner, SM; Ramspacher, A; Kreutzer, C; Hochmann, S; Tzotzos, S; Fischer, B; Strunk, D; Couillard-Despres, S; Kofler, B
17th Austrian Neuroscience Association Meeting; 28.-30.09.2021; Salzburg. 2021.
Mechanisms of neuronal maturation in the adult and
aging brain
Reisinger, M; Benedetti, B; Gabriele, G; Kreutzer, C; Poupardin, R; Couillard-Despres, S
17th Austrian Neuroscience Association Meeting; 28.-30.09.2021; Salzburg. 2021.
Enhancing functional recovery through intralesional application of extracellular vesicles in a rat model of traumatic spinal cord injury
Romanelli, P; Bieler, L; Heimel, P; Skokic, S; Jakubecova, D; Kreutzer, C; Zaunmair, P; Smolcic, T; Benedetti, B; Rohde, E; Gimona, M; Hercher, D; Dobrivojevic Radmilovic, M; Couillard-Despres, S
Neuroscience 2021; 08.-11.11.2021; Virtual. 2021.
Functional recovery through intralesional application of extracellular vesicles in a rat model of traumatic spinal cord injury
Romanelli, P; Bieler, L; Heimel, P; Skokic, S; Jakubecova, D; Kreutzer, C; Zaunmair, P; Smolcic, T; Benedetti, B; Rohde, E; Gimona, M; Hercher, D; Dobrivojevic Radmilovic, M; Couillard-Despres, S
PMU Virtual Science Get Together 2021; 02.07.2021; Salzburg. 2021.
Transcriptomic characterization of brain CD8+ T-cells identifies gene signature of tissue resident memory T-cells in Alzheimer's disease transgenic mice
Unger, M; Altendorfer, B; Poupardin,R; Hoog, A; Fordter, J; Benedetti, B; Benedetti, A; Asslaber, D; Egle, A; Aigner, L,
PMU Science Get Together; 02.07.-31.10.2021; virtuell. 2021.
Book chapters
Frozen-to-Paraffin: Categorization of Histological Frozen Sections by the Aid of Paraffin Sections and Generative Adversarial Networks
Gadermayr, M; Tschuchnig, M; Stangassinger, LM; Kreutzer, C; Couillard-Despres, S; Oostingh, GJ; Hittmair, A
In: (Eds. Svoboda, D; Burgos, N; Wolterink, JM; Zhao, C) editors(s). Simulation and Synthesis in Medical Imaging. Switzerland: Springer Nature ; p. 99–109. (ISBN: 978-3-030-87591-6)
2020
Journal Articles
Structural and Functional Maturation of Rat Primary Motor Cortex Layer V Neurons.
Benedetti, B; Dannehl, D; Janssen, JM; Corcelli, C; Couillard-Després, S; Engelhardt, M;
Int J Mol Sci. 2020; 21(17):
Full papers/articles (Journal)
Functional Integration of Neuronal Precursors in the Adult Murine Piriform Cortex.
Benedetti, B; Dannehl, D; König, R; Coviello, S; Kreutzer, C; Zaunmair, P; Jakubecova, D; Weiger, TM; Aigner, L; Nacher, J; Engelhardt, M; Couillard-Després, S;
Cereb Cortex. 2020; 30(3):1499-1515
Full papers/articles (Journal)
DCX+ neuronal progenitors contribute to new oligodendrocytes during remyelination in the hippocampus
Klein, B; Mrowetz, H; Kreutzer, C; Rotheneichner, P; Zaunmair, P; Lange, S; Coras, R; Couillard-Despres, S; Rivera, FJ; Aigner, L;
Sci Rep. 2020; 10(1): 20095
Full papers/articles (Journal)
Generation of myogenic progenitor cell-derived smooth muscle cells for sphincter regeneration.
Thurner, M; Deutsch, M; Janke, K; Messner, F; Kreutzer, C; Beyl, S; Couillard-Després, S; Hering, S; Troppmair, J; Marksteiner, R;
Stem Cell Res Ther. 2020; 11(1): 233
Full papers/articles (Journal)
Extracellular vesicles from human multipotent stromal cells protect against hearing loss after noise trauma in vivo.
Warnecke, A; Harre, J; Staecker, H; Prenzler, N; Strunk, D; Couillard-Despres, S; Romanelli, P; Hollerweger, J; Lassacher, T; Auer, D; Pachler, K; Wietzorrek, G; Köhl, U; Lenarz, T; Schallmoser, K; Laner-Plamberger, S; Falk, CS; Rohde, E; Gimona, M;
Clin Transl Med. 2020; 10(8): e262
Full papers/articles (Journal)
Unpublished conference presentations
Diflapolin and its derivates: New drugs to alleviate inflammatory response after spinal cord injury
Bieler, L; Planitzer, T; Vieider, L; Matuszczak, B; Schuster, D; Couillard-Després, S
PMU virtual Science Get Together 2020; 28.06.- 31.08.2020; Salzburg (virtual). 2020.
Effect of Hop-extract on Neurogenesis and Neuroinflammation
Rivera FJ, Mansilla J, Sanchez E, Hinrichsen B, Krugmann C, Bieler L, Simirgiotis M, Couillard-Despres S, Aigner L, Silva ME
ReBrain – Coupling Circulation to CNS International Conference at the Faculty of Medicine, Universidad Austral de Chile; 22.-24.01.2020; Valdivia. 2020.
Impact of local application of extracellular vesicles on spinal cord injury
Romanelli, P; Couillard-Despres, S;
Austrian Cluster for Tissue Regeneration Annual Meeting
; 17.-18.02.2020; Wien. 2020.
MSCs-derived extracellular vesicles improve motor recovery and alleviate pathological hallmarks of spinal cord injury.
Romanelli, P; Jakubecova, D; Bieler, L; Kreutzer, C; Zaunmair, P; Rohde, E; Gimona, M; Skokic, S; Dobrivojevic, M; Couillard-Després, S
Science Get Together; 26.06.2020; Salzburg. 2020.
PSA DEPLETION INDUCES THE DIFFERENTIATION OF IMMATURE NEURONS IN THE PIRIFORM CORTEX OF ADULT MICE
S. Coviello, M. Bellés-Esteller, Y. Gramuntell-Roch, P. Klimczak, B. Benedetti,S. Couillard-Després, J. Nacher
FENS; 11-15.07.2020; Virtual European Forum. 2020.
Motor cortex plasticity and impact of extracellular vesicles after spinal cord injury
Sebastien Couillard-Despres
3rd INTERREG - 8th TERMIS Winterschool
on "Musculoskeletal Tissue Regeneration: From Mechanobiology to in Vitro/in Vivo Models and Advanced Imaging"; 12.-15.01.2020; Radstadt. 2020.
Getting a better start for regeneration after spinal cord injury: what we are learning from the rat model
Sebastien Couillard-Despres
ReBrain: Coupling circulation to CNS; 22.-24.01.2020; Valdivia. 2020.
Inversion-Recovery T1w MRI enables accurate localization of cysts after traumatic spinal cord injury
Skokic, S; Romanelli, P; Heimel, P; Bieler, L; Zaunmair, P; Jakubecova, D; Hercher, D; Dobrivojevic Radmilovic, M; Couillard-Despres, S
15th Annual Meeting of the European Society for Molecular Imaging ESMI; 24.-27.03.2020; Virtual. 2020.
2019
Journal Articles
Early functional connectivity deficits and progressive microstructural alterations in the TgF344-AD rat model of Alzheimer"s Disease: A longitudinal MRI study.
Anckaerts, C; Blockx, I; Summer, P; Michael, J; Hamaide, J; Kreutzer, C; Boutin, H; Couillard-Després, S; Verhoye, M; Van der Linden, A;
Neurobiol Dis. 2019; 124:93-107
Full papers/articles (Journal)
The Prenylflavonoid ENDF1 Overrules Central Nervous System Growth Inhibitors and Facilitates Regeneration of DRG Neurons.
Bieler, L; Vogl, M; Kirchinger, M; Urmann, C; Riepl, H; Bandtlow, C; Klimaschewski, L; Aigner, L; Couillard-Despres, S;
FRONT CELL NEUROSCI. 2019; 13: 332
Full papers/articles (Journal)
Stroke Accelerates and Uncouples Intrinsic and Synaptic Excitability Maturation of Mouse Hippocampal DCX
Ceanga, M; Keiner, S; Grünewald, B; Haselmann, H; Frahm, C; Couillard-Després, S; Witte, OW; Redecker, C; Geis, C; Kunze, A;
J Neurosci. 2019; 39(9): 1755-1766.
Full papers/articles (Journal)
Development and Characterization of the Neuroregenerative Xanthohumol C/Hydroxypropyl-β-cyclodextrin Complex Suitable for Parenteral Administration.
Kirchinger, M; Bieler, L; Tevini, J; Vogl, M; Haschke-Becher, E; Felder, TK; Couillard-Després, S; Riepl, H; Urmann, C;
Planta Med. 2019; 85(16):1233-1241
Full papers/articles (Journal)
Dimethylsulfoxide Inhibits Oligodendrocyte Fate Choice of Adult Neural Stem and Progenitor Cells.
OSullivan, A; Lange, S; Rotheneichner, P; Bieler, L; Aigner, L; Rivera, FJ; Couillard-Despres, S;
Front Neurosci. 2019; 13:1242
Full papers/articles (Journal)
Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination.
Rivera, FJ; de la Fuente, AG; Zhao, C; Silva, ME; Gonzalez, GA; Wodnar, R; Feichtner, M; Lange, S; Errea, O; Priglinger, E; OSullivan, A; Romanelli, P; Jadasz, JJ; Brachtl, G; Greil, R; Tempfer, H; Traweger, A; Bátiz, LF; Küry, P; Couillard-Despres, S; Franklin, RJM; Aigner, L;
Glia. 2019; 67(8):1510-1525
Full papers/articles (Journal)
Extracellular Vesicles Can Deliver Anti-inflammatory and Anti-scarring Activities of Mesenchymal Stromal Cells After Spinal Cord Injury.
Romanelli, P; Bieler, L; Scharler, C; Pachler, K; Kreutzer, C; Zaunmair, P; Jakubecova, D; Mrowetz, H; Benedetti, B; Rivera, FJ; Aigner, L; Rohde, E; Gimona, M; Strunk, D; Couillard-Despres, S;
Front Neurol. 2019; 10: 1225
Full papers/articles (Journal)
Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells.
Silva, ME; Lange, S; Hinrichsen, B; Philp, AR; Reyes, CR; Halabi, D; Mansilla, JB; Rotheneichner, P; de la Fuente, AG; Couillard-Despres, S; Batiz, LF; Franklin, RJM; Aigner, L; Rivera, FJ
FRONT CELL NEUROSCI. 2019; 13: 85
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
ENDF-1, a hops-derived prenylated flavonoid, enhances neurite growth and complexity in DRG neurons despite extracellular matrix inhibitors.
Bieler, L; Vogl, M; Kirchinger, M; Urmann, C; Riepl, H; Bandtlow, C; Klimaschewski, L; Aigner, L; Couillard-Despres, S
Instrinsic Activity. 2019; -16th ANA - 25th APHAR Meeting Innsbruck 2019; 25. -27.09.2019; Innsbruck.
Abstracts (Journal)
Study of neurodifferentiation potential of different extracts of Bacopa monnieri
Ritter, S; Urmann, C; Bieler, L; Couillard-Despres, S; Riepl, H
PLANTA MED. 2019; 85(18): 1549-1549.
Abstracts (Journal)
Soluble factors derived from brain pericytes promote neural stem cells to generate oligodendrocytes
Rivera, FJ; Silva, ME; Lange, S; Hinrichsen, B; Philp, AR; Reyes, CR; Halabi, D; Mansilla, J; Rotheneichner, P; de la Fuente, AG; Couillard-Despres, S; Batiz, LF; Franklin, RJ; Aigner, L
GLIA. 2019; 67: E686-E687.
Abstracts (Journal)
Extracellular vesicles (EVs) improve motor recovery and reduce inflammation in a rat model of spinal cord injury
Romanelli, P; Jakubecova, D; Bieler, L; Kreutzer, C; Zaunmair, P;Rohde, E; Gimona, M; Couillard-Despres, S;
Extracellular vesicles (EVs) improve motor recovery and reduce inflammation in a rat model of spinal cord injury . 2019; -ANA/APHAR Meeting Innsbruck; 25.-27.09.2019; Innsbruck.
Abstracts (Journal)
Study of neurodifferentiation potential of different extracts of Bacopa monnieri
S. Ritter, C. Urmann, L. Bieler, S. Couillard-Despres, H. Riepl
PLANTA MEDICA. 2019; 85(18): 1549-- 67th International Congress and Annual Meeting of the Society-for-Medicinal-Plant-and-Natural-Product-Research (GA); 01.-05.09.2019; Innsbruck.
Abstracts (Journal)
Unpublished conference presentations
First-in-human application of umbilical cord MSC-derived EVs for the prevention of fibrosis following cochlear implant surgery
A. Warnecke, J. Schulze, J. Hollerweger, T. Lassacher, H.-M. Binder, A. Desgeorges, G. Weidler, P. Romanelli, S. Couillard-Despres, H. Staecker, J. Nelson-Brantley, A. Traweger, E. Rohde & M. Gimona
Annual Meeting International Society for Extracellular Vesicles; 24.-28.04.2019; Kyoto. 2019.
Spinal cord injury causes increased excitability of axotomized layer V neurons in the primary motor cortex
Benedetti, B; Dannehl, D; Thoma, C; Bieler, L; Janssen, JM; Verdong, J; Corcelli, C; Schultz, C; Engelhardt, M; Couillard-Despres, S
PMU Science Get Together; 28.06.2019; Nürnberg. 2019.
Spinal cord injury causes increased excitability in axotomized layer V neurons of the primary motor cortex
Benedetti, B; Dannehl, D; Thome, C; Bieler, LS; Janssen, JM; Verdong, J; Corcelli, C; Schultz, C; Engelhardt, M; Couillard-Després, S;
16th ANA - 25th APHAR Meeting Innsbruck 2019; 25.-27.09.2019; Innsbruck. 2019.
Structural and functional maturation profile of rat primary motor cortex layer 5b neurons
Benedetti, N; Dannehl, D; Janssen, JM; Corcelli, C; Couillard-Despres, S; Engelhardt, M
Neuroscience 2019; 18.-23.10.2019; Chicago. 2019.
The prenylflavonoid ENDF1 overrules central nervous system growth inhibitors and facilitates regeneration of DRG neurons.
Bieler, L; Vogl, M; Kirchinger, M; Urmann, C; Riepl, H; Bandtlow, C; Klimascheski, L; Aigner, L; Couillard-Despres, S
PMU Science get together 2019; 28.06.2019; Nürnberg. 2019.
Non-proliferative precursors in the adult brain
What are new neurons doing in an old network?
Bruno Benedetti
Neuroscience Day; 29.11.2019; Salzburg. 2019.
Spinal cord injury causes increased excitability in axotomized layer V neurons of the primary motor cortex
Bruno Benedetti, Dominik Dannehl, Christian Thome, Lara Sophie Bieler, Jan Maximilian Janssen, Jona Verdong, Corinna Corcelli, Christian Schultz,
Maren Engelhardt, Sébastien Couillard-Després
SCI-TReCS retreat; 16-17.09.2019; Wagrain. 2019.
Spinal cord injury causes increased excitability in axotomized layer V neurons of the primary motor cortex
Bruno Benedetti, Dominik Dannehl, Christian Thome, Lara Sophie Bieler, Jan Maximilian Janssen, Jona Verdong, Corinna Corcelli, Christian Schultz,
Maren Engelhardt, Sébastien Couillard-Després
SCI-TReCS RETREAT; 16-17.09.2019; Wagrain, Salzburg. 2019.
Structural and functional maturation of rat primary motor cortex layer 5 neurons
Bruno Benedetti, Dominik Dannehl, Christian Thome, Lara Sophie Bieler, Jan Maximilian Janssen, Jona Verdong, Corinna Corcelli, Christian Schultz, Maren Engelhardt, Sébastien Couillard-Després
SCI-TReCS retreat; 16-17.09.2019; Wagrain. 2019.
Structural and functional maturation profile of rat primary motor cortex layer Vb neurons
Bruno Benedetti, Dominik Dannehl, Jan Maximilian Janssen, Corinna Corcelli, Sebastién Couillard-Després, Maren Engelhardt
Society for Neuroscience meeting 2019; 19-23.10.2019; Chicago. 2019.
Physiology and integration of non-proliferative neuronal precursors in the piriform cortex
Bruno Benedetti, Dominik Dannehl, Richard König, Simona Coviello Christina Kreutzer , Pia Zaunmair, Dominika Jakubecova, Thomas M. Weiger, Ludwig Aigner, Juan Nacher, Maren Engelhardt3, Sébastien Couillard-Després
SCI-TReCS retreat; 16-17.09.2019; Wagrain. 2019.
Research strategies to minimize damage and restore connectivity in a broken spinal cord
Couillard-Despres, S;
Neuroscience Day 2019; 29.11.2019; Salzburg. 2019.
Neuroprotektive Aktivität von Extrazellulären Vesikeln aus Stromazellen
Couillard-Despres, S;
55. Jahrestagung der Östereichische Gesellschaft für Unfallchirurgie; 03.-05-10.2019; Salzburg. 2019.
Monitoring secondary damages after spinal cord injury in a rat model
Couillard-Despres, S;
Austrian Cluster for Tissue Regeneration Annual Meeting; 11.-12.03.2019; Vienna. 2019.
Acute Application of Extracellular Vesicles to Limit Secondary Damages after SCI
Couillard-Després, S;
2nd INTERREG - 7th TERMIS Winterschool 2019, Musculoskeletal Tissue Regeneration: From Mechanobiology to in Vitro/in Vivo Models and Advanced Imaging.; 13.-16.01.2019; Radstadt. 2019.
Functional integration of neuronal precursors in the adult murine piriform cortex
Couillard-Despres, S; Benedetti, B; Dannehl, D; König, R; Coviello, S; Kreutzer, C; Zaunmair, P; Jakubecova, D; Weiger, TM; Aigner, L; Nacher, J; Engelhardt, M
16th ANA - 25th APHAR Meeting Innsbruck; 25.-27.09.201; Innsbruck. 2019.
Remodeling of M1 layer Vb pyramidal cell axon initial segments and their axo-axonic innervation pattern after spinal cord lesion
Dominik Dannehl, Bruno Benedetti, Christian Thome, Lara Bieler, Jan Maximilian Janssen, Corinna Corcelli, Radhika Puttagunta, Sebastien Couillard-Despres, Maren Engelhardt
13th Göttingen Meeting of the German Neuroscience Society; 0.-23.03.20; Göttingen. 2019.
Neuroregeneration and plasticity in the adult central nervous system: Two models of neuroregeneration analyzed by Ultramicroscopy
Jährling, N; Benedetti, B; Bieler, L; Saghafi, S; Becker, K; Dodt, HU; Couillard-Despres, S
Engineerging in Medicine and Biology Conference; 23.-27.07.2019; Berlin. 2019.
Lightsheet Microscopy: Ultramicroscopy in fundamental neuroscience research
Jährling, N; Couillard-Després, S; Becker, K; Saghafi, S; Wegenast-Braun, BM; Kramer, E; Weiler, R; Dodt, HU;
Deutsche Gesellschaft für klinische Neurophysiologie und funktionelle Bildgebungé; 28.-30.03.2019; Freiburg. 2019.
Neuroprotektive Aktivität von Extrazellulären Vesikeln aus Stromazellen
R, Rohde; Couillard-Despres, S;
Austria Spinal Cord Injury Study - Frühjahrstagung 2019; 09-10.05.2019; Linz. 2019.
Soluble Factors Derived from Brain Pericytes Promote Neural Stem Cells to Generate Oligodendrocytes
Rivera Francisco J., Maria Elena Silva, Simona Lange, Bryan Hinrichsen, Amber Philp, Carolina R. Reyes, Diego Halabi, Josselyne Mansilla, Peter Rotheneichner, Alerie Guzman de la Fuente, Sebastien Couillard-Despres, Luis F. Bátiz, Robin J.M. Franklin, Ludwig Aigner
XIV European Meeting on Glial Cells in Health and Disease (GLIA 2019); 10.-13.07.2019; Oporto. 2019.
Therapeutic potential of the vesicular secretome of human stromal cells
Rohde, E; Hollerweger, J; Lassacher, T; Schallmoser, K; Schulze, J; Warnecke, A; Romanelli, P; Couillard-Despres, S; Traweger, A; Strunk, D; Gimona, M
52. Jahrestagung der Deutschen Gesellschaft für Transfusionsmedizin und Immunhämatologie (DGTI); 18.-20.09.2019; Mannheim. 2019.
Intra parenchymal application of MSC-derived extracellular vesicles improves motor recovery and reduces inflammation in a traumatic spinal cord injury rat model
Romanelli, P; Jakubecova, D; Bieler, L; Kreutzer, C; Zaunmair, P;Rohde, E; Gimona, M; Couillard-Despres, S;
Science Get Together; 28.06.2019; Nurnberg. 2019.
Intra parenchymal application of MSC-derived extracellular vesicles improves motor recovery and reduces inflammation in a traumatic spinal cord injury rat model
Romanelli, P; Jakubecova, D; Bieler, L; Kreutzer, C; Zaunmair, P;Rohde, E; Gimona, M; Couillard-Despres, S;
SCI-TReCS RETREAT; 16-17.09.2019; Wagrain. 2019.
Extracellular vesicles (EVs) improve motor recovery and reduce inflammation in a rat model of spinal cord injury
Romanelli, P; Jakubecova, D; Bieler, L; Kreutzer, C; Zaunmair, P;Rohde, E; Gimona, M; Couillard-Despres, S;
SCI-TReCS RETREAT ; 16-17.09.2019; Wagrain. 2019.
Neuronal precursors in the piriform cortex: delayed developmental neurogenesis or new encoding elements?
Sebastien Couillard-Despres
Master Program for Neurobiology; 11.02.2019; Valencia. 2019.
Neue Nervenzellen für das erwachsene Gehirn: Wunsch, Möglichkeit oder Realität
Sebastien Couillard-Despres
Wissensdurst 2019; 07.-09.05.2019; Salzburg. 2019.
Book chapters
DCX-Related Disorders.
Hehr, U; Uyanik, G; Aigner, L; Couillard-Despres, S; Winkler, J;
In: Adam, MP; Ardinger, HH; Pagon, RA; Wallace, SE; Bean, LJH; Stephens, K; Amemiya, A; editors. editors(s). GeneReviews.. Seattle: University of Washington;
2018
Journal Articles
Motor deficits following dorsal corticospinal tract transection in rats: voluntary versus skilled locomotion readouts.
Bieler, L; Grassner, L; Zaunmair, P; Kreutzer, C; Lampe, L; Trinka, E; Marschallinger, J; Aigner, L; Couillard-Despres, S;
Heliyon. 2018; 4(2): e00540
Full papers/articles (Journal)
Retinal Pericytes: Characterization of Vascular Development-Dependent Induction Time Points in an Inducible NG2 Reporter Mouse Model.
Bruckner, D; Kaser-Eichberger, A; Bogner, B; Runge, C; Schrödl, F; Strohmaier, C; Silva, ME; Zaunmair, P; Couillard-Despres, S; Aigner, L; Rivera, FJ; Reitsamer, HA; Trost, A;
Curr Eye Res. 2018; 43(10): 1274-1285.
Full papers/articles (Journal)
Role of putative voltage-sensor countercharge D4 in regulating gating properties of Ca
Costé de Bagneaux, P; Campiglio, M; Benedetti, B; Tuluc, P; Flucher, BE;
Channels (Austin). 2018; 12(1): 249-261.
Full papers/articles (Journal)
Proseek single-plex protein assay kit system to detect sAxl and Gas6 in serological material of brain tumor patients.
Jaksch-Bogensperger, H; Hammerschmid, A; Aigner, L; Trinka, E; Gehwolf, R; Ebner, Y; Hutterer, M; Couillard-Despres, S;
Biotechnol Rep (Amst). 2018; 18: e00252
Full papers/articles (Journal)
Selection of Tissue Factor-Deficient Cell Transplants as a Novel Strategy for Improving Hemocompatibility of Human Bone Marrow Stromal Cells
Oeller, M; Laner-Plamberger, S; Hochmann, S; Ketterl, N; Feichtner, M; Brachtl, G; Hochreiter, A; Scharler, C; Bieler, L; Romanelli, P; Couillard-Despres, S; Russe, E; Schallmoser, K; Strunk, D
THERANOSTICS. 2018; 8(5): 1421-1434.
Full papers/articles (Journal)
Bioluminescence imaging visualizes osteopontin-induced neurogenesis and neuroblast migration in the mouse brain after stroke
Rogall, R; Rabenstein, M; Vay, S; Bach, A; Pikhovych, A; Baermann, J; Hoehn, M; Couillard-Despres, S; Fink, GR; Schroeter, M; Rueger, MA
STEM CELL RES THER. 2018; 9: 182
Full papers/articles (Journal)
Cellular Plasticity in the Adult Murine Piriform Cortex: Continuous Maturation of Dormant Precursors Into Excitatory Neurons
Rotheneichner, P; Belles, M; Benedetti, B; Konig, R; Dannehl, D; Kreutzer, C; Zaunmair, P; Engelhardt, M; Aigner, L; Nacher, J; Couillard-Despres, S
CEREB CORTEX. 2018; 28(7): 2610-2621.
Full papers/articles (Journal)
Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition.
Siebzehnrubl, FA; Reber, KA; Urbach, YK; Schulze-Krebs, A; Canneva, F; Moceri, S; Habermeyer, J; Achoui, D; Gupta, B; Steindler, DA; Stephan, M; Nguyen, HP; Bonin, M; Riess, O; Bauer, A; Aigner, L; Couillard-Despres, S; Paucar, MA; Svenningsson, P; Osmand, A; Andreew, A; Zabel, C; Weiss, A; Kuhn, R; Moussaoui, S; Blockx, I; Van der Linden, A; Cheong, RY; Roybon, L; Petersen, A; von Horsten, S
P NATL ACAD SCI USA. 2018; 115(37): E8765-E8774.
Full papers/articles (Journal)
Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-β plaques: A potential role in shaping plaque pathology?
Unger, MS; Marschallinger, J; Kaindl, J; Klein, B; Johnson, M; Khundakar, AA; Roßner, S; Heneka, MT; Couillard-Despres, S; Rockenstein, E; Masliah, E; Attems, J; Aigner, L;
Alzheimers Dement. 2018; 14(8): 1022-1037.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Benedetti, B; König, R; Dannehl, D; Kreutzer, C; Belles, M; Ritter, M; Weiger, TM; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S;
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex. 2018; -Paracelsus Science Get Together 2018; 29.06.2018; Salzburg.
Abstracts (Journal)
Maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Couillard-Després, S
Maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex. 2018; -ÖGMBT; 17.9.2018-19.9.2018; Wien.
Abstracts (Journal)
Probing the Voltage-Sensing Mechanism of Ca(V)1.1 Calcium Channels at Single Channel Resolution
de Bagneaux, PC; Benedetti, B; Tuluc, P; Campiglio, M; Flucher, B
BIOPHYS J. 2018; 114(3): 637A-637A.
Abstracts (Journal)
Unpublished conference presentations
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Benedett, B; König, B; Dannehl, D; Kreutzer, C ; Belles, M; Ritter, M; Weiger, TM; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S;
SfN Neuroscience Meeting San Diego 2018; 03.-07.11.2018; San Diego. 2018.
Remodeling of the axon initial segment in layer 5 primary motor cortex after distal axotomy
Dannehl,D; Benedetti, B; Bieler, LS; Corcelli, C; Soleymani, S; Ewertz, M; Couillard Despres, S; Engelhardt; M;
FENS Berlin 2018; 07.-11.07.2018; Berlin. 2018.
Functional and structural deficits in a novel transgenic rat model of Alzheimer’s Disease.
Anckaerts, C; Blockx, I; Kreutzer, C; Boutin, H; Couillard-Despres , S; Verhoye, M; Van der Linden, A;
13th annual meeting of the European Society for Molecular Imaging - ESMI; 20 - 23.03 2018; San Sebastián. 2018.
Functional and Structural deficits in a novel transgenic rat model of Alzheimer`s Disease.
Anckaerts, CH; Blockx, I; Kreutzer, C; Boutin, H; Couillard-Després, S; et.al.
2018; -ISMRM-ESMRMB Joint Annual Meeting; 16.-21.06.2018; Paris.
Longitudinal in vivo MRI assessment of functional connectivity and structural integrity in the TgF344-AD rat model of Alzheimer`s Disease
Anckaerts, CH; Blockx, I; Summer, P; Michael, J; Kreutzer, C; Boutin, H; Couillard-Després, S; Verhoye, M; Van der Linden, A
EMIM 2018; 20.-23.03.2018; San Sebastiàn. 2018.
Intrinsic excitability and synaptic plasticity of motor cortex layer 5 neurons
Benedetti, B;
Neurosceince Day, Salzburg; 20.09.2018; Salzburg. 2018.
Structural and functional maturation of the AIS in rat primary motor cortex
Benedetti, B; Dannehl, D; Janssen, JM; Engelhardt, M; Couillard-Després, S;
Axon in the Hills; 04.05.10.2018; Heidelberg. 2018.
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Benedetti, B; König, R; Dannehl, D; Kreutzer, C; Belles, M; Ritter, M; Weiger, TM; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S;
Paracelsus Science Get Together; 29.06.2018; Salzburg. 2018.
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Benedetti, B; König, R; Dannehl, D; Kreutzer, C; Belles, M; Ritter, M; Weiger, TM; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S;
2018; -11th FENS, Forum of Neuroscience; 07-11.07.2018; Berlin.
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Benedetti, B; König, R; Dannehl, D; Kreutzer, C; Belles, M; Ritter, M; Weiger, TM; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S;
Adult Neurogenesis (ABCAM meeting) 2018; 02.-04.05.2018; Dresden. 2018.
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Benedetti, B; König, R; Dannehl, D; Kreutzer, C; Belles, M; Ritter, M; Weiger, TM; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S;
Neuroscience Day, Salzburg; 20.09.2018; Salzburg. 2018.
ENDF1 – a prenylated flavonoid- neutralizes inhibitory effect of ECM proteins on axonal regrowth
Bieler, L; Vogl, M; Kirchinger, M; Urmann, C; Riepl, H; Aigner, L; Couillard-Després, S
FENS Forum 2018; 07.-11.07.2018; Berlin. 2018.
ENDF1 – a prenylated flavonoid- neutralizes inhibitory effect of ECM proteins on axonal regrowth
Bieler, L; Vogl, M; Kirchinger, M; Urmann, C; Riepl, H; Aigner, L; Couillard-Després, S
Paracelsus Science get to together; 29.06.2018; Paracelsus Medizinische Privatuniversität Salzburg. 2018.
ENDF1, a hops-derived neuroregenerative flavonoid to enhance neurite regrowth
Bieler, L; Vogl, M; Kirchinger, M; Urmann, C; Tevini, J; Felder, T; Aigner, L; Riepl, H; Couillard-Despres, S
SfN Meeting; 03.-07.11.2018; San Diego, California. 2018.
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Bruno Benedetti Richard König, Dominik Dannehl, Christina Kreutzer, Maria Belles, Markus Ritter, Thomas M. Weiger, Juan Nacher, Maren Engelhardt, Ludwig Aigner, Sébastien Couillard-Després
Axons in the hills
; 04.05.10.2018; Heidelberg. 2018.
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Bruno Benedetti, Richard König, Dominik Dannehl, Christina Kreutzer, Maria Belles, Markus Ritter, Thomas M. Weiger, Juan Nacher, Maren Engelhardt, Ludwig Aigner,
Sébastien Couillard-Després
FENS meeting Berlin; 07.-11.07.2018; Berlin. 2018.
Experimentelle Neuroregeneration: Was ist heute schon möglich?
Couillard-Després, S;
Symposium: Neues aus der Neurologie und Neurorehabilitation.
Medical Park Loipl, Klinik für Neurologie; 08. - 09.06.2018; Berchtesgaden und Bischofswiesen. 2018.
Structural and functional remodeling of the axon initial segment in rat primary motor cortex principal neurons after spinal cord lesion
Dannehl,D; Benedetti,B; Thome, C; Bieler, L; Janssen, JM; Verdong, J; Corcelli, C; Schultz, C; Couillard-Després, S; Engelhardt, M
SfN Meeting; 03.-07.11.2018; San Diego, Kalifornien. 2018.
Aging Hampers the Ability of Mesenchymal Stem Cells to Promote the Generation of Oligodendrocytes During CNS Remyelination
Rivera , F; Guzman de la Fuente, A; Zhao; C; Silva, ME; Wodnar, R; Feichtner, M; Lange, S; Errea, O; Gonzalez, G; Oberbauer, E; O´ Sullivan, A; Jadasz, J; Brachtl, G; Greil, R; Tempfer, H; Traweger, A; Bátiz, LF; Küry, P; Couillard-Despres,S., Aigner L
11th FENS, Forum of the Federation of European Neurosciences Societies (FENS); 07.-11.07.2018; Berlin. 2018.
Ageing Limits the Ability of Mesenchymal Stem Cells to Enhance the Generation of Remyelinating Oligodendrocytes – Consequences for the Development of New Therapies for the Treatment of Multiple Sclerosis.
Rivera, F; Guzman de la Fuente, A; Zhao, C; Silva, ME; Wodnar, R; Feichtner, M; Lange, S; Errea, O; Gonzalez, G; Oberbauer, E; O´ Sullivan, A; Jadasz, JJ; Brachtl, G; Greil, R; Tempfer, H; Traweger, A; Bátiz, LF; Küry, P; Couillard-Despres, S; Franklin, RJM; Aigner, L;
Paracelsus Science get together; 29.06.2018; Salzburg. 2018.
Mesenchymal stromal cell-derived extracellular vesicles alleviate major pathological hallmarks of spinal cord injury
Romanelli, P; Bieler, L; Scharler, C; Pachler, C; Kreutzer, C. Zaunmair, C; Aigner, L; Rivera, F; Rohde, E; Benedetti, B; Schallmoser, K; Gimona, M; Strunk, D; Couillard-Despres, S;
FENS; 07.-11.07.2018; Berlin. 2018.
Mesenchymal stromal cell-derived extracellular vesicles alleviate major pathological hallmarks of spinal cord injury
Romanelli, P; Bieler, L; Scharler, C; Pachler, C; Kreutzer, C. Zaunmair, C; Aigner, L; Rivera, F; Rohde, E; Benedetti, B; Schallmoser, K; Gimona, M; Strunk, D; Couillard-Despres, S;
Science Get Together; 29.06.2018; Salzburg. 2018.
Mesenchymal stromal cell- derived extracellular vesicles alleviate major pathological hallmarks of spinal cord injury
Romanelli, P; Bieler, L; Scharler, C; Pachler, C; Kreutzer, C; Zaunmair, P; Aigner, L; Rivera, F; Rohde, E; Benedetti, B; Schallmoser, K; Gimona, M; Strunk, D; Couillard-Despres, S;
SFN; 03-07.11.2018; San Diego. 2018.
2017
Journal Articles
Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis.
Adamczak, J; Aswendt, M; Kreutzer, C; Rotheneichner, P; Riou, A; Selt, M; Beyrau, A; Uhlenküken, U; Diedenhofen, M; Nelles, M; Aigner, L; Couillard-Despres, S; Hoehn, M;
Neurobiol Dis. 2017; 99: 47-57.
Full papers/articles (Journal)
Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination.
De La Fuente, AG; Lange, S; Silva, ME; Gonzalez, GA; Tempfer, H; van Wijngaarden, P; Zhao, C; Di Canio, L; Trost, A; Bieler, L; Zaunmair, P; Rotheneichner, P; OSullivan, A; Couillard-Despres, S; Errea, O; Mäe, MA; Andrae, J; He, L; Keller, A; Bátiz, LF; Betsholtz, C; Aigner, L; Franklin, RJM; Rivera, FJ;
Cell Rep. 2017; 20(8):1755-1764
Full papers/articles (Journal)
In vivo bioluminescence imaging of neurogenesis - the role of the blood brain barrier in an experimental model of Parkinson"s disease.
Fricke, IB; Schelhaas, S; Zinnhardt, B; Viel, T; Hermann, S; Couillard-Després, S; Jacobs, AH;
Eur J Neurosci. 2017; 45(7): 975-986.
Full papers/articles (Journal)
Tamoxifen Activation of Cre-Recombinase Has No Persisting Effects on Adult Neurogenesis or Learning and Anxiety.
Rotheneichner, P; Romanelli, P; Bieler, L; Pagitsch, S; Zaunmair, P; Kreutzer, C; König, R; Marschallinger, J; Aigner, L; Couillard-Després, S;
Front Neurosci. 2017; 11: 27
Full papers/articles (Journal)
Lymphatic and vascular markers in an optic nerve crush model in rat.
Trost, A; Bruckner, D; Kaser-Eichberger, A; Motloch, K; Bogner, B; Runge, C; Strohmaier, C; Couillard-Despres, S; Reitsamer, HA; Schroedl, F;
Exp Eye Res. 2017; 159:30-39
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Pericytes promote the generation of oligodendrocytes during remyelination
Guzman, A; Lange, S; Silva, ME; Gonzalez, GA; Tempfer, H; van Wijngaarden, P; Zhao, C; Rotheneichner, P; Trost, A; OxxxSullivan, A; Couillard-Despres, S; Bieler, L; Errea, O; Mae, MA; Andrae, J; He, L; Keller, A; Betsholtz, C; Aigner, L; Franklin, RJM; Rivera, FJ
GLIA. 2017; 65: E541-E542.
Abstracts (Journal)
Neuroprotective activity of mesenchymal stromal cells and their secreted vesicles in a spinal cord contusion rat model
Romanelli, P; Bieler, L; Scharler, C; Pachler, K; Kreutzer, C; Zaunmair, P; Aigner, L; Rivera, FJ; Rohde, E; Benedetti, B; Gimona, M; Strunk, D; Couillard-Despres, S
TRANSFUS MED HEMOTH. 2017; 44: 76-76.
Abstracts (Journal)
Unpublished conference presentations
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult piriform cortex
Benedetti, B; König, R; Dannehl, D; Kreutzer, C; Belles, M; Ritter, M; Weiger, T; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S
ANA meeting; 24.-26.09.2017; Institute of Science and Technology / Wien. 2017.
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult piriform cortex
Benedetti, B; König, R; Dannehl, D; Kreutzer, C; Belles, M; Ritter, M; Weiger, T; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S
SCI-TReCS retreat; 11.-12.09.2017; Kloster Seon / Seeon-Seebruck. 2017.
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult piriform cortex
Benedetti, B; König, R; Dannehl, D; Kreutzer, C; Belles, M; Ritter, M; Weiger, T; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S
Paracelsus Science Get Together; 23.06.2017; Nürnberg. 2017.
Motor and Sensory Assessments after CST transection – tasks to study functional tract regeneration in vivo
Bieler, L; Grassner, L; Zaunmair, P; Kreutzer, C; Aigner, L; Couillard-Després, S
SCITReCS - Retreat; 11.-12.09.2017; Kloster Seeon. 2017.
ENDF1 as treatment to restore peripheral nerve function after sciatic nerve crush
Bieler, L; Jakob, L; Vogl, M; Urmann, C; Kirchinger, M; Tevini, J; Riepl, H; Felder, T; Aigner, L; Couillard-Després, S
Science get together ; 11.-12.09.2017; Kloster Seeon. 2017.
ENDF1 as treatment to restore peripheral nerve function after sciatic nerve crush
Bieler, L; Jakob, L; Vogl, M; Urmann, C; Kirchinger, M; Tevini, J; Riepl, H; Felder, T; Aigner, L; Couillard-Després, S
SCITReCS - Retreat; 11.-12.09.2017; Kloster Seeon. 2017.
ENDF1 as treatment to restore peripheral nerve function after sciatic nerve crush
Bieler, L; Jakob, L; Vogl, M; Urmann, C; Kirchinger, M; Tevini, J; Riepl, H; Felder, T; Aigner, L; Couillard-Després, S
Science get together ; 23.06.2017; Nürnberg. 2017.
ENDF1 as treatment to restore peripheral nerve function after sciatic nerve crush
Bieler, L; Jakob, L; Vogl, M; Urmann, C; Kirchinger, M; Tevini, J; Riepl, H; Felder, T; Aigner, L; Couillard-Després, S
Science get together ; 11.-12.09.2017; Kloster Seeon. 2017.
ENDF1- a prenylated hops-derived flavonoid- as treatment to restore peripheral nerve function after sciatic nerve crush (SNC)
Bieler, L; Jakob, L; Vogl, M; Urmann, C; Kirchinger, M; Tevini, J; Riepl, H; Felder, T; Aigner, L; Couillard-Després, S
ANA-Meeting; 24.-26.09.2017; Klosterneuburg. 2017.
Functional Maturation of tangled cells into glutamatergic neurons within the adult mouse piriform cortex
Dannehl, D; Belles, M; Rotheneichner, P; König, R; Benedetti, B; Kreutzer, C; Zaunmair, P; Aigner, L; Nacher, J; Engelhardt, M; Couillard-Despres, S;
Neuroscience 2017; 11-15.11.2017; Washington. 2017.
The Role of Galanin Receptors 2 and 3 in adult neurogenesis, learning and anxiety.
Nowack, L; Bieler, L; Locker, F; Stockinger, J; Zaunmair, P; Kreutzer, C; Kofler, B; Couillard-Despres, S
Science get together; 23.06.2017; Nürnberg. 2017.
Bioluminescence imaging visualizes osteopontin-induced neurogenesis and neuroblasts migration in the mouse brain after stroke
Rogall, R; Pikhovych, A; Bach, A; Vay, S; Baermann, J; Hoehn, M; Couillard-Despres, S; Fink, GR; Schroeter, M; Rueger, AB;
12th European Molecular Imaging Meeting; 05-07.04.2017; Cologne. 2017.
Neuroprotective Activity of Mesenchymal Stromal Cells and their Secreted Vesicles in a Spinal Cord Contusion Rat Model
Romanelli, P; Bieler, L; Scharler, C; Pachler, K; Kreutzer, C; Zaunmair, P; Aigner, L; Rivera, F; Rohde, E; Benedetti, B; Gimona, M; Strunk, D; Couillard-Despres, S;
Science Get Together ; 23.06.2017; Nurnberg . 2017.
Neuroprotective Activity of Mesenchymal Stromal Cells and their Secreted Vesicles in a Spinal Cord Contusion Rat Model
Romanelli, P; Bieler, L; Scharler, C; Pachler, K; Kreutzer, C; Zaunmair, P; Aigner, L; Rivera, F; Rohde, E; Benedetti, B; Gimona, M; Strunk, D; Couillard-Despres, S;
ANA Meeting; 24-26.09.2017; Wien. 2017.
Amyloid-beta plaque associated cellular plasticity in Alzheimer’s disease
Unger, M; Marschallinger, J; Klein, B; Johnson, M; Khundakar, A; Heneka, M; Couillard-Despres, S; Masliah, E; Attems, J; Aigner, L
ADPD2017, 13th International Conference on Alzheimer’s and Parkinson’s Disease, Vienna; 28.03.-02.04.2017; Wien. 2017.
Book chapters
Pathophysiology of traumatic spinal cord injury
Couillard-Despres, S; Bieler, L; Vogl, M;
In: Weidner, N; Rupp, R; Tansey, K (Eds.) editors(s). Neurological Aspects of Spinal Cord Injury. Switzerland: Springer International Publishing; p. 503-528. (ISBN: 978-3-319-46291-2)
2016
Journal Articles
Expression of Lymphatic Markers in the Adult Rat Spinal Cord.
Kaser-Eichberger, A; Schroedl, F; Bieler, L; Trost, A; Bogner, B; Runge, C; Tempfer, H; Zaunmair, P; Kreutzer, C; Traweger, A; Reitsamer, HA; Couillard-Despres, S;
Front Cell Neurosci. 2016; 10: 23
Full papers/articles (Journal)
B-ring modification in prenylflavonoids of hops and the effect on induction of neuronal differentiation.
Kirchinger, M; Urmann, C; Bieler, L; Couillard-Despres, S; Riepl, H;
Planta Med. 2016; 81(S 01):-S381.
Abstracts (Journal)
Distribution and fate of DCX/PSA-NCAM expressing cells in the adult mammalian cortex: A local reservoir for adult cortical neuroplasticity?
König, R; Benedetti, B; Rotheneichner, P; O'Sullivan, A; Kreutzer, C; Belles, M; Nacher, J; Weiger, TM; Aigner, L; Couillard-Despres, S
Frontiers in Biology. 2016; 11(3): 193-213.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Expression of the precursor marker Sox2 in the myenteric plexus in the caecum of postnatal and adult mouse
Grundmann, D; Loris, E; Marx, L; Wilms, E; Aigner, L; Couillard-Despres, S; Reinhardt, C; Schafer, KH
NEUROGASTROENT MOTIL. 2016; 28: 51-51.
Abstracts (Journal)
Unpublished conference presentations
Spinal Cord Injury in the Aged - a Neglected Issue
Bieler, L; Gradnitzer, U; König, A; Zaunmair, P; Kreutzer, Ch; Couillard-Despres, S
FENS Forum; 02.-06.07.2016; Kopenhagen. 2016.
Course of motor recovery after SCI aged and young rats: a
comparative study
Bieler, L; Gradnitzer, U; König, A; Zaunmair, P; Kreutzer, Ch; Couillard-Despres, S
SCITReCS Summit; 27.10.2016; Salzburg. 2016.
Course of motor recovery after SCI in aged and young rats: A comparative study
Bieler, L; Romanelli, P; Gradnitzer, U; König, A; Zaunmair, P; Kreutzer, Ch; Couillard-Despres, S
PMU Science get together; 24.06.2016; Salzburg. 2016.
Adult Neurogenesis in Physiology and Disease
Couillard-Despres, S;
Eurogenesis 2016; 11-13.07.2016; Bordeaux. 2016.
A consumable reservoir of immature neurons: an ususpected form of adult cortical neurogenesis
Couillard-Despres, S; Rotheneichner, P; Belles, M; König, R; Benedetti, B; Kreutzer, C; Zaunmair, P; Aigner, L; Nacher, J;
10th FENS Forum of Neuroscience; 2-6.07.2016; Copenhagen. 2016.
Neuroprotective Activity of MSPCs and their Vesicles in a Spinal Cord Contusion Rat Model
Romanelli, P; Bieler, L; Scharler, C; Pachler, K; Kreutzer, C; Zaunmair, P; Aigner, L; Rivera, F; Gimona, M; Strunk, D; Couillard-Despres, S;
SCITReCS Summit; 27.10.2016; Salzburg. 2016.
ENDF1 neutralises extracellular matrix associated inhibitor effect on DRG neurons outgrowth
Vogl, M; Bieler, L; Roustan, V; Urmann, C; Riepl, H; Aigner, L; Weckwerth, W; Couillard-Després, S
10 th FENS Forum of Neuroscience; 02.-06.07.2016; Kopenhagen. 2016.
Morphological and proteomic responses of neuronal cells to ENDF1
Vogl, M; Bieler, L; Roustan, V; Urmann, C; Riepl, H; Aigner, L; Weckwerth, W; Couillard-Després, S
PMU Science Get Together; 24.06.2016; Salzburg. 2016.
Morphological and proteomic responses of neuronal cells to ENDF1
Vogl, M; Bieler, L; Roustan, V; Urmann, C; Riepl, H; Aigner, L; Weckwerth, W; Couillard-Després, S
Eurogenesis; 11.-13.07.2017; Bordeaux. 2016.
Book chapters
Chapter 7 – Aging
König, R; Rotheneichner, P; Marschallinger, J; Aigner, L; Couillard-Despres, S;
In: Canales, JJ editors(s). Adult Neurogenesis in the Hippocampus. Academic Press; p. 145-176. (ISBN: 9780128019771)
2015
Journal Articles
Analysis of Neurogenesis during Experimental Autoimmune Encephalomyelitis Reveals Pitfalls of Bioluminescence Imaging.
Ayzenberg, I; Schlevogt, S; Metzdorf, J; Stahlke, S; Pedreitturia, X; Hunfeld, A; Couillard-Despres, S; Kleiter, I;
PLoS One. 2015; 10(3): e0118550
Full papers/articles (Journal)
Reduction in subventricular zone-derived olfactory bulb neurogenesis in a rat model of Huntington"s disease is accompanied by striatal invasion of neuroblasts.
Kandasamy, M; Rosskopf, M; Wagner, K; Klein, B; Couillard-Despres, S; Reitsamer, HA; Stephan, M; Nguyen, HP; Riess, O; Bogdahn, U; Winkler, J; von Horsten, S; Aigner, L
PLoS One. 2015; 10(2):e0116069
Full papers/articles (Journal)
Lesion-induced accumulation of platelets promotes survival of adult neural stem / progenitor cells.
Kazanis, I; Feichtner, M; Lange, S; Rotheneichner, P; Hainzl, S; Öller, M; Schallmoser, K; Rohde, E; Reitsamer, HA; Couillard-Despres, S; Bauer, HC; Franklin, RJ; Aigner, L; Rivera, FJ;
Exp Neurol. 2015; 269: 75-89.
Full papers/articles (Journal)
The L-type calcium channel Cav1.3 is required for proper hippocampal neurogenesis and cognitive functions.
Marschallinger, J; Sah, A; Schmuckermair, C; Unger, M; Rotheneichner, P; Kharitonova, M; Waclawiczek, A; Gerner, P; Jaksch-Bogensperger, H; Berger, S; Striessnig, J; Singewald, N; Couillard-Despres, S; Aigner, L;
Cell Calcium. 2015; 58(6): 606-616.
Full papers/articles (Journal)
Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.
Marschallinger, J; Schäffner, I; Klein, B; Gelfert, R; Rivera, FJ; Illes, S; Grassner, L; Janssen, M; Rotheneichner, P; Schmuckermair, C; Coras, R; Boccazzi, M; Chishty, M; Lagler, FB; Renic, M; Bauer, HC; Singewald, N; Blümcke, I; Bogdahn, U; Couillard-Despres, S; Lie, DC; Abbracchio, MP; Aigner, L;
Nat Commun. 2015; 6: 8466
Full papers/articles (Journal)
Neurodifferentiating potential of 8-prenylnaringenin and related compounds in neural precursor cells and correlation with estrogen-like activity.
Urmann, C; Oberbauer, E; Couillard-Després, S; Aigner, L; Riepl, H;
Planta Med. 2015; 81(4):305-311
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
CNS-pericytes promote oligodendrocyte fate decision and differentiation contributing to myelin development and repair
Lange, S; De La Fuente, AG; Rotheneichner, P; van Wijngaarden, P; Gonzalez, GA; Tempfer, H; Trost, A; Zhao, C; Couillard-Despres, S; Andrae, J; Betsholtz, C; Franklin, RJM; Aigner, L; Rivera, FJ
GLIA. 2015; 63: E289-E290.
Abstracts (Journal)
CNS lesion-induced accumulation of platelets promotes survival of adult SVZ-derived neural stem / progenitor cells
Rivera, F; Kazanis, I; Feichtner, M; Lange, S; Rotheneichner, P; Hainzl, S; Oller, M; Schallmoser, K; Rohde, E; Reitsamer, HA; Couillard-Despres, S; Bauer, HC; Franklin, RJM; Aigner, L
GLIA. 2015; 63: E403-E403.
Abstracts (Journal)
Structural modification of xanthohumol C and the effect on inducing differentiation in neural precursor cells
Urmann, C; Kirchinger, M; Bieler, L; Couillard-Despres, S; Aigner, L; Riepl, H
PLANTA MED. 2015; 81(16): 1417-1418.
Abstracts (Journal)
Unpublished conference presentations
Pathological course following traumatic spinal cord injury in a rat model.
Bieler, L; Gradnitzer, U; Zaunmair, P; Kreutzer, C; Couillard-Després, S
ANA-meeting; 23.-25.09.2015; Salzburg. 2015.
Beta - Cyclodextrins as nanocarriers for neuroregenerative flavonoids
Bieler, L; Vogl, M; Garnweidner, L; Urmann, C; Riepl, H; Aigner, L; Couillard-Després, S
SCITReCS-Summit 2015; 05.11.2015; Salzburg. 2015.
Beta-cyclodextrins as nanocarriers for neuroregenrative flavonoids.
Bieler, L; Vogl, M; Garnweidner-Reith, L; Urmann, C; Riepl, H; Aigner, L; Couillard-Després, S
ANA-Meeting ; 23.-25.09.2015; Salzburg. 2015.
Non-proliferative neurogenesis: an exhaustible source of plasticity?
Couillard-Despres, S;
Adult Neurogenesis, 3rd Provence Summer Workshop; 16-19.09.2015; Domaine des Escaunes. 2015.
Membrane physiology of immature neurons residing in the piriform cortex: evidence for non-proliferative neurogenesis
König, R, Rotheneichner, P; Benedetti, B; Kreutzer, C; Belles, M; Jakab, M; Weiger, T; Krautgartner, WD; Nacher, J; Aigner, L; Couillard-Despres, S
2015; -14th ANA Meeting; 23.-25.09.2015; Salzburg.
An exhaustible reservoir of immature neurons: an unsuspected form of adult neurogenesis
Rotheneichner, P; Belles, M; König, R; Kreutzer, C; Krautgartner, WD; Aigner, L; Nacher, J; Couillard-Despres, S;
14th Meeting of the Austrian Neuroscience Association; 23-25.09-2015; Salzburg. 2015.
ENDF1: A proregenerative flavonoid for spinal cord injury
Vogl, M; Bieler, L; Garnweidner-Raith, L; Urmann, C; Riepl, H; Aigner, A; Couillard-Després, S
Paracelsus Science Get Together; 03.06.2015; Nürnber. 2015.
ENDF1 and its pro-regenerative effects on postnatal DRG neurons
Vogl, M; Bieler, L; Urmann, C; Riepl, H; Aigner, A; Couillard-Després, S
SCI-TReCS Summit; 05.11.2015; Salzburg. 2015.
ENDF1 and its pro-regenerative effects on postnatal DRG neurons
Vogl, M; Bieler, L; Urmann, C; Riepl, H; Aigner, L; Couillard-Després, S;
ANA annual meeting; 23.09.2015; Salzburg. 2015.
2014
Journal Articles
Acute and chronic evolution of MRI findings in a case of posterior spinal cord ischemia.
Grassner, L; Klausner, F; Wagner, M; McCoy, M; Golaszewski, S; Leis, S; Aigner, L; Couillard-Despres, S; Trinka, E;
Spinal Cord. 2014;
Corrections
Acute and chronic evolution of MRI findings in a case of posterior spinal cord ischemia.
Grassner, L; Klausner, F; Wagner, M; McCoy, M; Golaszweski, S; Leis, S; Aigner, L; Couillard-Despres, S; Trinka, E;
Spinal Cord. 2014; 52 Suppl 1: S23-S24.
Case Reports
Cerebrolysin protects PC12 cells from CoCl2-induced hypoxia employing GSK3β signaling.
Hartwig, K; Fackler, V; Jaksch-Bogensperger, H; Winter, S; Furtner, T; Couillard-Despres, S; Meier, D; Moessler, H; Aigner, L;
Int J Dev Neurosci. 2014; 38: 52-58.
Full papers/articles (Journal)
Lactation-induced reduction in hippocampal neurogenesis is reversed by repeated stress exposure.
Hillerer, KM; Neumann, ID; Couillard-Despres, S; Aigner, L; Slattery, DA;
Hippocampus. 2014; 24(6):673-683
Full papers/articles (Journal)
Intrinsically Active and Pacemaker Neurons in Pluripotent Stem Cell-Derived Neuronal Populations
Illes, S; Jakab, M; Beyer, F; Gelfert, R; Couillard-Despres, S; Schnitzler, A; Ritter, M; Aigner, L
STEM CELL REP. 2014; 2(3): 323-336.
Full papers/articles (Journal)
TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons.
Kandasamy, M; Lehner, B; Kraus, S; Sander, PR; Marschallinger, J; Rivera, FJ; Trümbach, D; Ueberham, U; Reitsamer, HA; Strauss, O; Bogdahn, U; Couillard-Despres, S; Aigner, L;
J Cell Mol Med. 2014; 18(7):1444-1459
Full papers/articles (Journal)
Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis.
Marschallinger, J; Krampert, M; Couillard-Despres, S; Heuchel, R; Bogdahn, U; Aigner, L;
Exp Gerontol. 2014; 57: 149-154.
Full papers/articles (Journal)
Hippocampal neurogenesis and antidepressive therapy: shocking relations.
Rotheneichner, P; Lange, S; OSullivan, A; Marschallinger, J; Zaunmair, P; Geretsegger, C; Aigner, L; Couillard-Despres, S;
Neural Plast. 2014; 2014:723915
Reviews
Rat choroidal pericytes as a target of the autonomic nervous system.
Schrödl, F; Trost, A; Strohmaier, C; Bogner, B; Runge, C; Kaser-Eichberger, A; Couillard-Despres, S; Aigner, L; Reitsamer, HA;
Cell Tissue Res. 2014; 356(1):1-8
Full papers/articles (Journal)
Characterization of dsRed2-positive cells in the doublecortin-dsRed2 transgenic adult rat retina.
Trost, A; Schroedl, F; Marschallinger, J; Rivera, FJ; Bogner, B; Runge, C; Couillard-Despres, S; Aigner, L; Reitsamer, HA;
Histochem Cell Biol. 2014; 142(6):60-17
Full papers/articles (Journal)
Unpublished conference presentations
Functional readouts in a pre-clinical model of spinal cord injury
Couillard-Despres, S;
2014; -Interdisziplinäre Gruppe für Labor und Durchflusszytometrie (IGLD) Symposium 2014 ; 06-08.03.2014; Salzburg.
Molecular Aspects of Axonal Regeneration
Couillard-Despres, S;
11. Jahrestagung des Österreichischen Gesellschaft für Neurologie; 26-29.03.2014; Salzburg. 2014.
2013
Journal Articles
Boosting bioluminescence neuroimaging: an optimized protocol for brain studies.
Aswendt, M; Adamczak, J; Couillard-Despres, S; Hoehn, M;
PLOS ONE. 2013; 8(2): e55662
Full papers/articles (Journal)
Hippocampal neurogenesis and ageing.
Couillard-Després, S;
Curr Top Behav Neurosci. 2013; 15:343-355
Reviews
Sex-dependent regulation of hippocampal neurogenesis under basal and chronic stress conditions in rats.
Hillerer, KM; Neumann, ID; Couillard-Despres, S; Aigner, L; Slattery, DA;
Hippocampus. 2013; 23(6):476-487
Full papers/articles (Journal)
LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro.
Jiang, L; Brackeva, B; Stangé, G; Verhaeghen, K; Costa, O; Couillard-Després, S; Rotheneichner, P; Aigner, L; Van Schravendijk, C; Pipeleers, D; Ling, Z; Gorus, F; Martens, GA;
J Proteomics. 2013; 80:26-80
Full papers/articles (Journal)
Transforming growth factor-β1 primes proliferating adult neural progenitor cells to electrophysiological functionality.
Kraus, S; Lehner, B; Reichhart, N; Couillard-Despres, S; Wagner, K; Bogdahn, U; Aigner, L; Strauß, O;
Glia. 2013; 61(11):1767-1783
Full papers/articles (Journal)
Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective.
Oberbauer, E; Urmann, C; Steffenhagen, C; Bieler, L; Brunner, D; Furtner, T; Humpel, C; Bäumer, B; Bandtlow, C; Couillard-Despres, S; Rivera, FJ; Riepl, H; Aigner, L;
J Nutr Biochem. 2013; 24(11):1953-1962
Full papers/articles (Journal)
Neurogenesis and neuronal regeneration in status epilepticus.
Rotheneichner, P; Marschallinger, J; Couillard-Despres, S; Aigner, L;
Epilepsia. 2013; 54 Suppl 6:40-42
Reviews
Unpublished conference presentations
Electroconvulsive Therapy: Resetting Hippocampal Function via Neurogenesis?
Couillard-Despres, S;
Eurogenesis 2013; 24-26.06.2013; Bordeaux. 2013.
Cellular and Metabolic NeuroImaging: Looking for Neurogenesis.
Couillard-Despres, S;
Annual European Molecular Imaging Meeting; 26-28.05.2013; Turin. 2013.
2012
Journal Articles
Gene Expression Profiling of Neural Stem Cells and Their Neuronal Progeny Reveals IGF2 as a Regulator of Adult Hippocampal Neurogenesis
Bracko, O; Singer, T; Aigner, S; Knobloch, M; Winner, B; Ray, J; Clemenson, GD; Suh, H; Couillard-Despres, S; Aigner, L; Gage, FH; Jessberger, S
J NEUROSCI. 2012; 32(10): 3376-3387.
Full papers/articles (Journal)
SoxC Transcription Factors Are Required for Neuronal Differentiation in Adult Hippocampal Neurogenesis
Mu, LF; Berti, L; Masserdotti, G; Covic, M; Michaelidis, TM; Doberauer, K; Merz, K; Rehfeld, F; Haslinger, A; Wegner, M; Sock, E; Lefebvre, V; Couillard-Despres, S; Aigner, L; Berninger, B; Lie, DC
J NEUROSCI. 2012; 32(9): 3067-3080.
Full papers/articles (Journal)
In situ labeling and imaging of endogenous neural stem cell proliferation and migration.
Vande Velde, G; Couillard-Després, S; Aigner, L; Himmelreich, U; van der Linden, A;
WIRES NANOMED NANOBI. 2012; 4(6): 663-679.
Reviews
2011
Journal Articles
In vivo imaging of adult neurogenesis
Couillard-Despres, S; Aigner, L
EUR J NEUROSCI. 2011; 33(6): 1037-1044.
Full papers/articles (Journal)
Neurogenesis, Cellular Plasticity and Cognition: The Impact of Stem Cells in the Adult and Aging Brain - A Mini-Review
Couillard-Despres, S; Iglseder, B; Aigner, L
GERONTOLOGY. 2011; 57(6): 559-564.
Reviews
In vivo monitoring of adult neurogenesis in health and disease.
Couillard-Despres, S; Vreys, R; Aigner, L; Van der Linden, A;
Front Neurosci. 2011; 5: 67
Reviews
Inhibition of leukotriene receptors boosts neural progenitor proliferation.
Huber, C; Marschallinger, J; Tempfer, H; Furtner, T; Couillard-Despres, S; Bauer, HC; Rivera, FJ; Aigner, L;
Cell Physiol Biochem. 2011; 28(5):793-804
Full papers/articles (Journal)
The dark side of BrdU in neural stem cell biology: detrimental effects on cell cycle, differentiation and survival.
Lehner, B; Sandner, B; Marschallinger, J; Lehner, C; Furtner, T; Couillard-Despres, S; Rivera, FJ; Brockhoff, G; Bauer, HC; Weidner, N; Aigner, L;
Cell Tissue Res. 2011; 345(3):313-328
Full papers/articles (Journal)
Identity, fate and potential of cells grown as neurospheres: species matters.
Steffenhagen, C; Kraus, S; Dechant, FX; Kandasamy, M; Lehner, B; Poehler, AM; Furtner, T; Siebzehnrubl, FA; Couillard-Despres, S; Strauss, O; Aigner, L; Rivera, FJ;
Stem Cell Rev. 2011; 7(4):81-35
Full papers/articles (Journal)
The ageing systemic milieu negatively regulates neurogenesis and cognitive function
Villeda, SA; Luo, J; Mosher, KI; Zou, BD; Britschgi, M; Bieri, G; Stan, TM; Fainberg, N; Ding, ZQ; Eggel, A; Lucin, KM; Czirr, E; Park, JS; Couillard-Despres, S; Aigner, L; Li, G; Peskind, ER; Kaye, JA; Quinn, JF; Galasko, DR; Xie, XMS; Rando, TA; Wyss-Coray, T
NATURE. 2011; 477(7362): 90-U157.
Full papers/articles (Journal)
2010
Journal Articles
Stem cell quiescence in the hippocampal neurogenic niche is associated with elevated transforming growth factor-beta signaling in an animal model of Huntington disease.
Kandasamy, M; Couillard-Despres, S; Raber, KA; Stephan, M; Lehner, B; Winner, B; Kohl, Z; Rivera, FJ; Nguyen, HP; Riess, O; Bogdahn, U; Winkler, J; von Hörsten, S; Aigner, L;
J Neuropathol Exp Neurol. 2010; 69(7):717-728
Full papers/articles (Journal)
Deciphering the oligodendrogenic program of neural progenitors: cell intrinsic and extrinsic regulators.
Rivera, FJ; Steffenhagen, C; Kremer, D; Kandasamy, M; Sandner, B; Couillard-Despres, S; Weidner, N; Küry, P; Aigner, L;
Stem Cells Dev. 2010; 19(5):595-606
Reviews
A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons.
Zhang, J; Giesert, F; Kloos, K; Vogt Weisenhorn, DM; Aigner, L; Wurst, W; Couillard-Despres, S;
BMC Neurosci. 2010; 11:158
Full papers/articles (Journal)
2009
Journal Articles
Ageing abolishes the effects of fluoxetine on neurogenesis.
Couillard-Despres, S; Wuertinger, C; Kandasamy, M; Caioni, M; Stadler, K; Aigner, R; Bogdahn, U; Aigner, L;
MOL PSYCHIATR. 2009; 14(9): 85-64.
Full papers/articles (Journal)
Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein.
Marxreiter, F; Nuber, S; Kandasamy, M; Klucken, J; Aigner, R; Burgmayer, R; Couillard-Despres, S; Riess, O; Winkler, J; Winner, B;
EUR J NEUROSCI. 2009; 29(5): 87-90.
Full papers/articles (Journal)
A nuclear magnetic resonance biomarker for neural progenitor cells: is it all neurogenesis?
Ramm, P; Couillard-Despres, S; Plötz, S; Rivera, FJ; Krampert, M; Lehner, B; Kremer, W; Bogdahn, U; Kalbitzer, HR; Aigner, L;
Stem Cells. 2009; 27(2):420-423
Full papers/articles (Journal)
Mesenchymal stem cells promote oligodendroglial differentiation in hippocampal slice cultures.
Rivera, FJ; Siebzehnrubl, FA; Kandasamy, M; Couillard-Despres, S; Caioni, M; Poehler, AM; Berninger, B; Sandner, B; Bogdahn, U; Goetz, M; Bluemcke, I; Weidner, N; Aigner, L;
Cell Physiol Biochem. 2009; 24(3-4):317-324
Full papers/articles (Journal)
Striatal transplantation for multiple system atrophy - Are grafts affected by alpha-synucleinopathy?
Stefanova, N; Hainzer, M; Stemberger, S; Couillard-Despres, S; Aigner, L; Poewe, W; Wenning, GK
EXP NEUROL. 2009; 219(1): 368-371.
Full papers/articles (Journal)
Prolactin induces MAPK signaling in neural progenitors without alleviating glucocorticoid-induced inhibition of in vitro neurogenesis.
Wagner, K; Couillard-Despres, S; Lehner, B; Brockhoff, G; Rivera, FJ; Blume, A; Neumann, I; Aigner, L;
Cell Physiol Biochem. 2009; 24(5-6):397-406
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Live imaging of stroke induced neurogenesis in the mouse brain
Farr, TD; Kallur, T; Wiedermann, D; Couillard-Despres, S; Aigner, L; Hoehn, M
J CEREBR BLOOD F MET. 2009; 29: S544-S545.
Abstracts (Journal)
Effects of oligodendroglial alpha-synucleinopathy on striatal grafts in a transgenic mouse model of MSA
Stefanova, N; Hainzer, M; Stemberger, S; Couillard-Despres, S; Aigner, L; Poewe, W; Wenning, GK
MOVEMENT DISORD. 2009; 24: S48-S48.
Abstracts (Journal)
2008
Journal Articles
In vivo optical imaging of neurogenesis: watching new neurons in the intact brain.
Couillard-Despres, S; Finkl, R; Winner, B; Ploetz, S; Wiedermann, D; Aigner, R; Bogdahn, U; Winkler, J; Hoehn, M; Aigner, L;
Mol Imaging. 2008; 7(1): 28-34.
Full papers/articles (Journal)
Human in vitro reporter model of neuronal development and early differentiation processes.
Couillard-Despres, S; Quehl, E; Altendorfer, K; Karl, C; Ploetz, S; Bogdahn, U; Winkler, J; Aigner, L;
BMC Neurosci. 2008; 9: 31
Full papers/articles (Journal)
Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons.
Ladewig, J; Koch, P; Endl, E; Meiners, B; Opitz, T; Couillard-Despres, S; Aigner, L; Brüstle, O;
Stem Cells. 2008; 26(7): 1705-1712.
Full papers/articles (Journal)
Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis.
Mueller, AM; Pedré, X; Stempfl, T; Kleiter, I; Couillard-Despres, S; Aigner, L; Giegerich, G; Steinbrecher, A;
J Neuroinflammation. 2008; 5: 20
Full papers/articles (Journal)
Oligodendrogenesis of adult neural progenitors: differential effects of ciliary neurotrophic factor and mesenchymal stem cell derived factors.
Rivera, FJ; Kandasamy, M; Couillard-Despres, S; Caioni, M; Sanchez, R; Huber, C; Weidner, N; Bogdahn, U; Aigner, L;
J NEUROCHEM. 2008; 107(3): 832-843.
Full papers/articles (Journal)
Dopaminergic lesion enhances growth factor-induced striatal neuroblast migration.
Winner, B; Couillard-Despres, S; Geyer, M; Aigner, R; Bogdahn, U; Aigner, L; Kuhn, HG; Winkler, J;
J Neuropathol Exp Neurol. 2008; 67(2): 105-116.
Full papers/articles (Journal)
Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis.
Winner, B; Rockenstein, E; Lie, DC; Aigner, R; Mante, M; Bogdahn, U; Couillard-Despres, S; Masliah, E; Winkler, J;
Neurobiol Aging. 2008; 29(6): 913-925.
Full papers/articles (Journal)
2007
Journal Articles
Inhibition of Smad7, a negative regulator of TGF-beta signaling, suppresses autoimmune encephalomyelitis.
Kleiter, I; Pedré, X; Mueller, AM; Poeschl, P; Couillard-Despres, S; Spruss, T; Bogdahn, U; Giegerich, G; Steinbrecher, A;
J Neuroimmunol. 2007; 187(1-2):61-73
Full papers/articles (Journal)
Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington"s disease.
Kohl, Z; Kandasamy, M; Winner, B; Aigner, R; Gross, C; Couillard-Despres, S; Bogdahn, U; Aigner, L; Winkler, J;
Brain Res. 2007; 1155:24-33
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Modifying neurogenesis and the intrinsic migratory competence of neurons in the adult brain
Aigner, L; Couillard-Despres, S; Winkler, J; Bogdahn, U
J NEUROCHEM. 2007; 102: 242-242.
Abstracts (Journal)
2006
Journal Articles
Targeted transgene expression in neuronal precursors: watching young neurons in the old brain.
Couillard-Despres, S; Winner, B; Karl, C; Lindemann, G; Schmid, P; Aigner, R; Laemke, J; Bogdahn, U; Winkler, J; Bischofberger, J; Aigner, L;
Eur J Neurosci. 2006; 24(6): 153-145.
Full papers/articles (Journal)
Mesenchymal stem cells instruct oligodendrogenic fate decision on adult neural stem cells.
Rivera, FJ; Couillard-Despres, S; Pedre, X; Ploetz, S; Caioni, M; Lois, C; Bogdahn, U; Aigner, L;
Stem Cells. 2006; 24(10):2209-2219
Full papers/articles (Journal)
Transforming growth factor-beta1 is a negative modulator of adult neurogenesis.
Wachs, FP; Winner, B; Couillard-Despres, S; Schiller, T; Aigner, R; Winkler, J; Bogdahn, U; Aigner, L;
J Neuropathol Exp Neurol. 2006; 65(4):358-370
Full papers/articles (Journal)
Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb.
Winner, B; Geyer, M; Couillard-Despres, S; Aigner, R; Bogdahn, U; Aigner, L; Kuhn, G; Winkler, J;
Exp Neurol. 2006; 197(1):113-121
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Lineage selection of double cortin-positive human ES cell-derived neurons: an efficient tool for purification of transplantable immature neurons
Ladewig, J; Koch, P; Meiners, B; Itskovitz-Eldor, J; Couillard-Despres, S; Aigner, L; Brustle, O
ACTA NEUROPATHOL. 2006; 112(3): 367-367.
Abstracts (Journal)
2005
Journal Articles
Doublecortin expression levels in adult brain reflect neurogenesis.
Couillard-Despres, S; Winner, B; Schaubeck, S; Aigner, R; Vroemen, M; Weidner, N; Bogdahn, U; Winkler, J; Kuhn, HG; Aigner, L;
Eur J Neurosci. 2005; 21(1):-14
Full papers/articles (Journal)
Neuronal precursor-specific activity of a human doublecortin regulatory sequence.
Karl, C; Couillard-Despres, S; Prang, P; Munding, M; Kilb, W; Brigadski, T; Plötz, S; Mages, W; Luhmann, H; Winkler, J; Bogdahn, U; Aigner, L;
J Neurochem. 2005; 92(2):264-282
Full papers/articles (Journal)
2004
Journal Articles
Mitotic impairment by doublecortin is diminished by doublecortin mutations found in patients.
Couillard-Despres, S; Uyanik, G; Ploetz, S; Karl, C; Koch, H; Winkler, J; Aigner, L;
Neurogenetics. 2004; 5(2): 83-93.
Full papers/articles (Journal)
The neurogenic competence of progenitors from the postnatal rat retina in vitro.
Engelhardt, M; Wachs, FP; Couillard-Despres, S; Aigner, L;
Exp Eye Res. 2004; 78(5): 1025-1036.
Full papers/articles (Journal)
2003
Journal Articles
Somatic mosaicism and variable penetrance in doublecortin-associated migration disorders.
Aigner, L; Uyanik, G; Couillard-Despres, S; Ploetz, S; Wolff, G; Morris-Rosendahl, D; Martin, P; Eckel, U; Spranger, S; Otte, J; Woerle, H; Holthausen, H; Apheshiotis, N; Fluegel, D; Winkler, J;
Neurology. 2003; 60(2): 329-332.
Full papers/articles (Journal)
Transient expression of doublecortin during adult neurogenesis.
Brown, JP; Couillard-Després, S; Cooper-Kuhn, CM; Winkler, J; Aigner, L; Kuhn, HG;
J Comp Neurol. 2003; 467(1): 1-10.
Full papers/articles (Journal)
Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1.
Nguyen, MD; Boudreau, M; Kriz, J; Couillard-Després, S; Kaplan, DR; Julien, JP;
J Neurosci. 2003; 23(6):2131-2140
Full papers/articles (Journal)
High efficacy of clonal growth and expansion of adult neural stem cells.
Wachs, FP; Couillard-Despres, S; Engelhardt, M; Wilhelm, D; Ploetz, S; Vroemen, M; Kaesbauer, J; Uyanik, G; Klucken, J; Karl, C; Tebbing, J; Svendsen, C; Weidner, N; Kuhn, HG; Winkler, J; Aigner, L;
Lab Invest. 2003; 83(7):949-962
Full papers/articles (Journal)
2002
Conference papers, proceedings, abstracts
Adult neural stem cells: Improvement of culture conditions for clonal expansion
Wilhelm, D; Couillard-Despres, S; Wachs, FP; Plate, KH; Winkler, J; Kuhn, HG; Aigner, L
ACTA NEUROPATHOL. 2002; 104(5): 576-576.
Abstracts (Journal)
2001
Journal Articles
Molecular mechanisms of neuronal migration disorders, quo vadis?
Couillard-Despres, S; Winkler, J; Uyanik, G; Aigner, L;
Curr Mol Med. 2001; 1(6): 677-688.
Reviews
2000
Journal Articles
Extra axonal neurofilaments do not exacerbate disease caused by mutant Cu,Zn superoxide dismutase.
Couillard-Després, S; Meier, J; Julien, JP;
Neurobiol Dis. 2000; 7(4): 462-470.
Full papers/articles (Journal)
1999
Journal Articles
Disruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunits.
Jacomy, H; Zhu, Q; Couillard-Després, S; Beaulieu, JM; Julien, JP;
J Neurochem. 1999; 73(3): 972-984.
Full papers/articles (Journal)
Extra neurofilament NF-L subunits rescue motor neuron disease caused by overexpression of the human NF-H gene in mice.
Meier, J; Couillard-Després, S; Jacomy, H; Gravel, C; Julien, JP;
J Neuropathol Exp Neurol. 1999; 58(10): 1099-1110.
Full papers/articles (Journal)
1998
Journal Articles
Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase.
Couillard-Després, S; Zhu, Q; Wong, PC; Price, DL; Cleveland, DW; Julien, JP;
Proc Natl Acad Sci U S A. 1998; 95(16): 9626-9630.
Full papers/articles (Journal)
Transgenic mice in the study of ALS: the role of neurofilaments.
Julien, JP; Couillard-Després, S; Meier, J;
Brain Pathol. 1998; 8(4): 759-769.
Reviews
1997
Journal Articles
Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments.
Zhu, Q; Couillard-Després, S; Julien, JP;
Exp Neurol. 1997; 148(1): 299-316.
Full papers/articles (Journal)