KIESSLICH TOBIAS
Department of Internal Medicine I - Division of Gastroenterology, Hepatology, Nephrology, Metabolism and Diabetology
Institute of Physiology and Pathophysiology
Publications
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Researcher Profile
183 Publications
2023
Journal Articles
Evaluation of Tazemetostat as a Therapeutically Relevant Substance in Biliary Tract Cancer.
Bekric, D; Neureiter, D; Ablinger, C; Dobias, H; Beyreis, M; Ritter, M; Jakab, M; Bischof, J; Koller, U; Kiesslich, T; Mayr, C;
Cancers (Basel). 2023; 15(5):
Full papers/articles (Journal)
HDACs as an emerging target in endocrine tumors: a comprehensive review.
Klieser, E; Neumayer, B; Di Fazio, P; Mayr, C; Neureiter, D; Kiesslich, T;
Expert Rev Endocrinol Metab. 2023; 18(2):143-154
Full papers/articles (Journal)
2022
Journal Articles
Ferroptosis in Hepatocellular Carcinoma: Mechanisms, Drug Targets and Approaches to Clinical Translation.
Bekric, D; Ocker, M; Mayr, C; Stintzing, S; Ritter, M; Kiesslich, T; Neureiter, D;
Cancers (Basel). 2022; 14(7):
Reviews
Can We Efficiently Target HDAC in Cancer?
Kiesslich, T; Neureiter, D;
Cancers (Basel). 2022; 14(16):
Editorials
Chemoresistance and resistance to targeted therapies in biliary tract cancer: what have we learned?
Mayr, C; Kiesslich, T; Modest, DP; Stintzing, S; Ocker, M; Neureiter, D;
Expert Opin Investig Drugs. 2022; 31(2): 221-233.
Full papers/articles (Journal)
MicroRNA mimics can distort physiological microRNA effects on immune checkpoints by triggering an antiviral interferon response.
Prinz, F; Jonas, K; Balihodzic, A; Klec, C; Reicher, A; Barth, DA; Riedl, J; Gerger, A; Kiesslich, T; Mayr, C; Rinner, B; Kargl, J; Pichler, M;
RNA Biol. 2022; 19(1): 1305-1315.
Full papers/articles (Journal)
New method for real-time visualization and quantitative characterization of early colorectal cancer in endoscopy: a pilot study.
Wagner, A; Zandanell, S; Ziachehabi, A; Mitrakov, A; Klieser, E; Neureiter, D; Kiesslich, T; Mayr, C; Berr, F; Fedoruk, M; Singhartinger, F; Holzinger, J;
Endosc Int Open. 2022; 10(8):E1147-E1154
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Cdk5 as a possible new target in biliary tract cancer: preliminary in-situ findings.
Wilhelm, F; Klieser, E; Neumayer, B; Winkelmann, P; Jäger, T; Pachmayr, J; Ardelt, M; Huber-Cantonati, P; Ablinger, C; Pancis, I; Ritter, M; Kiesslich, T; Mayr, C; Neureiter, D
Zeitschrift für Gastroenterologie.. 2022; 60(01):e32-e32.-38. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium
der Leber; 28.-29.01.2022; Mannheim.
Abstracts (Journal)
2021
Journal Articles
Citation inequality and the Journal Impact Factor: median, mean, (does it) matter?
Kiesslich, T; Beyreis, M; Zimmermann, G; Traweger, A
SCIENTOMETRICS. 2021;
Full papers/articles (Journal)
HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer.
Mayr, C; Kiesslich, T; Erber, S; Bekric, D; Dobias, H; Beyreis, M; Ritter, M; Jäger, T; Neumayer, B; Winkelmann, P; Klieser, E; Neureiter, D;
Cancers (Basel). 2021; 13(15):
Full papers/articles (Journal)
HDAC-targeting epigenetic drug screening for biliary tract cancer.
Mayr, C; Kiesslich, T; Erber, S; Bekric, D; Dobias, H; Ritter, M; Jäger, T; Neumayer, B; Winkelmann, P; Klieser, E; Neureiter, D;
Ann Hepatobiliary Pancreat Surg. 2021; 25(Suppl 1): S397
Notes
The challenges of combinatory immunotherapy for biliary tract cancer.
Neureiter, D; Mayr, C; Kiesslich, T;
Expert Opin Investig Drugs. 2021; 30(6):591-594
Editorials
Immunmodulatory Treatment Strategies of Hepatocellular Carcinoma: From Checkpoint Inhibitors Now to an Integrated Approach in the Future.
Ocker, M; Mayr, C; Kiesslich, T; Stintzing, S; Neureiter, D;
Cancers (Basel). 2021; 13(7):
Reviews
MiR-200c-3p Modulates Cisplatin Resistance in Biliary Tract Cancer by ZEB1-Independent Mechanisms.
Posch, F; Prinz, F; Balihodzic, A; Mayr, C; Kiesslich, T; Klec, C; Jonas, K; Barth, DA; Riedl, JM; Gerger, A; Pichler, M;
Cancers (Basel). 2021; 13(16):
Full papers/articles (Journal)
Systematic Review on Optical Diagnosis of Early Gastrointestinal Neoplasia.
Wagner, A; Zandanell, S; Kiesslich, T; Neureiter, D; Klieser, E; Holzinger, J; Berr, F;
J Clin Med. 2021; 10(13):
Reviews
Unpublished conference presentations
HDAC Class I Inhibitor Romidepsin as a novel and promising Epigenetic Drug for Biliary Tract Cancer.
Mayr, C; Kiesslich, T; Erber, S; Bekric, D; Dobias, H; Ritter, M; Jäger, T; Neumayer, B. Winkelmann, P; Klieser, E; Neureiter, D
Cholangiocarcinoma Foundation (CCF) Annual Conference 2021; 31.03.-02.04.2021; Herriman, Utah (virtuell). 2021.
HDAC-targeting Epigenetic Drug Screening for Biliary Tract Cancer.
Mayr, C; Kiesslich, T; Erber, S; Bekric, D; Dobias, H; Ritter, M; Jäger, T; Neumayer, B. Winkelmann, P; Klieser, E; Neureiter, D
HBP Surgery Week 2021 & 54th Annual Congress of the Korean Association of HBP Surgery; 25.03.-27.03.2021; Seoul. 2021.
2020
Journal Articles
Long Non-Coding RNAs in Biliary Tract Cancer-An Up-to-Date Review.
Bekric, D; Neureiter, D; Ritter, M; Jakab, M; Gaisberger, M; Pichler, M; Kiesslich, T; Mayr, C;
J Clin Med. 2020; 9(4):
Reviews
Feasibility of Kahoot! as a Real-Time Assessment Tool in (Histo-)pathology Classroom Teaching
Neureiter, D; Klieser, E; Neumayer, B; Winkelmann, P; Urbas, R; Kiesslich, T
ADV MED EDUC PRACT. 2020; 11: 695-705.
Full papers/articles (Journal)
How do we choose the appropriate chemotherapeutic agents for biliary tract cancer?
Neureiter, D; Mayr, C; Kiesslich, T;
Expert Opin Pharmacother. 2020; 21(3):243-245
Editorials
Expression of the microRNA-200 Family, microRNA-205, and Markers of Epithelial-Mesenchymal Transition as Predictors for Endoscopic Submucosal Dissection over Esophagectomy in Esophageal Adenocarcinoma: A Single-Center Experience.
Neureiter, D; Mayr, C; Winkelmann, P; Neumayer, B; Klieser, E; Wagner, A; Hufnagl, C; Emmanuel, K; Holzinger, J; Koch, O; Kiesslich, T; Varga, M;
Cells. 2020; 9(2):
Full papers/articles (Journal)
Hot Spot TERT Promoter Mutations Are Rare in Sporadic Pancreatic Neuroendocrine Neoplasms and Associated with Telomere Length and Epigenetic Expression Patterns.
Posch, A; Hofer-Zeni, S; Klieser, E; Primavesi, F; Naderlinger, E; Brandstetter, A; Filipits, M; Urbas, R; Swiercynski, S; Jäger, T; Winkelmann, P; Kiesslich, T; Lu, L; Neureiter, D; Stättner, S; Holzmann, K;
Cancers (Basel). 2020; 12(6):
Full papers/articles (Journal)
A Preoperative Clinical Risk Score Including C-Reactive Protein Predicts Histological Tumor Characteristics and Patient Survival after Surgery for Sporadic Non-Functional Pancreatic Neuroendocrine Neoplasms: An International Multicenter Cohort Study.
Primavesi, F; Andreasi, V; Hoogwater, FJH; Partelli, S; Wiese, D; Heidsma, C; Cardini, B; Klieser, E; Marsoner, K; Fröschl, U; Thalhammer, S; Fischer, I; Göbel, G; Hauer, A; Kiesslich, T; Ellmerer, P; Klug, R; Neureiter, D; Wundsam, H; Sellner, F; Kornprat, P; Függer, R; Öfner, D; Nieveen van Dijkum, EJM; Bartsch, DK; de Kleine, RHJ; Falconi, M; Stättner, S;
Cancers (Basel). 2020; 12(5):
Full papers/articles (Journal)
Generation of An Endogenous FGFR2-BICC1 Gene Fusion/58 Megabase Inversion Using Single-Plasmid CRISPR/Cas9 Editing in Biliary Cells.
Reicher, A; Harris, AL; Prinz, F; Kiesslich, T; Wei, M; Öllinger, R; Rad, R; Pichler, M; Kwong, LN;
Int J Mol Sci. 2020; 21(7):
Full papers/articles (Journal)
2019
Journal Articles
Downregulation of SPARC Is Associated with Epithelial-Mesenchymal Transition and Low Differentiation State of Biliary Tract Cancer Cells.
Aghamaliyev, U; Gaitantzi, H; Thomas, M; Simon-Keller, K; Gaiser, T; Marx, A; Yagublu, V; Araos, J; Cai, C; Valous, NA; Halama, N; Kiesslich, T; Ebert, M; Grützmann, R; Rückert, F; Breitkopf-Heinlein, K;
Eur Surg Res. 2019; 60(1-2):1-12
Full papers/articles (Journal)
The Cancer Stem Cell Inhibitor Napabucasin (BBI608) Shows General Cytotoxicity in Biliary Tract Cancer Cells and Reduces Cancer Stem Cell Characteristics.
Beyreis, M; Gaisberger, M; Jakab, M; Neureiter, D; Helm, K; Ritter, M; Kiesslich, T; Mayr, C;
Cancers (Basel). 2019; 11(3):
Full papers/articles (Journal)
Low VDAC1 Expression Is Associated with an Aggressive Phenotype and Reduced Overall Patient Survival in Cholangiocellular Carcinoma.
Feichtinger, RG; Neureiter, D; Kemmerling, R; Mayr, JA; Kiesslich, T; Kofler, B;
Cells. 2019; 8(6):
Full papers/articles (Journal)
NRF2: The key to tumor- and patient-dependent chemosensitivity in biliary tract cancer?
Kiesslich, T; Mayr, C; Neureiter, D;
EBioMedicine. 2019; 49:9-10
Full papers/articles (Journal)
HDAC inhibitors in liver cancer: which route to take?
Kiesslich, T; Neureiter, D;
Expert Rev Gastroenterol Hepatol. 2019; 13(6): 515-517.
Editorials
The Crosstalk of miRNA and Oxidative Stress in the Liver: From Physiology to Pathology and Clinical Implications.
Klieser, E; Mayr, C; Kiesslich, T; Wissniowski, T; Fazio, PD; Neureiter, D; Ocker, M;
Int J Mol Sci. 2019; 20(21):
Reviews
Size matters! Association between journal size and longitudinal variability of the Journal Impact Factor.
Koelblinger, D; Zimmermann, G; Weineck, SB; Kiesslich, T;
PLoS One. 2019; 14(11): e0225360
Full papers/articles (Journal)
Continuous, label-free, 96-well-based determination of cell migration using confluence measurement.
Mayr, C; Beyreis, M; Dobias, H; Gaisberger, M; Fuchs, J; Pichler, M; Ritter, M; Jakab, M; Helm, K; Neureiter, D; Kiesslich, T;
Cell Adh Migr. 2019; 13(1):76-82
Full papers/articles (Journal)
Hepatocellular carcinoma: Therapeutic advances in signaling, epigenetic and immune targets
Neureiter, D; Stintzing, S; Kiesslich, T; Ocker, M
WORLD J GASTROENTERO. 2019; 25(25): 3136-3150.
Reviews
Exploring the surgical landscape of pancreatic neuroendocrine neoplasia in Austria: Results from the ASSO pNEN study group.
Primavesi, F; Klieser, E; Cardini, B; Marsoner, K; Fröschl, U; Thalhammer, S; Fischer, I; Hauer, A; Urbas, R; Kiesslich, T; Neureiter, D; Zitt, M; Klug, R; Wundsam, H; Sellner, F; Karner, J; Függer, R; Cakar-Beck, F; Kornprat, P; Öfner, D; Stättner, S;
Eur J Surg Oncol. 2019; 45(2):198-206
Full papers/articles (Journal)
Pancreatic cancer in young adults: changes, challenges, and solutions.
Primavesi, F; Stättner, S; Schlick, K; Kiesslich, T; Mayr, C; Klieser, E; Urbas, R; Neureiter, D;
Onco Targets Ther. 2019; 12: 3387-3400.
Reviews
Book chapters
Histopathology of Early Mucosal Neoplasias: Morphologic Carcinogenesis in the GI Tract
Neureiter, D; Kiesslich, T
In: Berr, F; Oyama, T; Ponchon, T; Yahagi, N. editors(s). Atlas of Early Neoplasias of the Gastrointestinal Tract - Endoscopic Diagnosis and Therapeutic Decisions. Springer International Publishing; p. 25-45. (ISBN: 978-3-030-01114-7)
2018
Journal Articles
Evidence-based Surgery of Aortic Regurgitation: Results of a Questionnaire in German-speaking Countries.
Dinges, C; Steindl, J; Hitzl, W; Kiesslich, T; Seitelberger, R;
Thorac Cardiovasc Surg. 2018; 66(4):287-293
Full papers/articles (Journal)
The potential predictive value of tumor budding for neoadjuvant chemoradiotherapy response in locally advanced rectal cancer.
Jäger, T; Neureiter, D; Fallaha, M; Schredl, P; Kiesslich, T; Urbas, R; Klieser, E; Holzinger, J; Sedlmayer, F; Emmanuel, K; Dinnewitzer, A;
Strahlenther Onkol. 2018; 194(11):991-1006
Full papers/articles (Journal)
Glycine Induces Migration of Microglial BV-2 Cells via SNAT-Mediated Cell Swelling.
Kittl, M; Dobias, H; Beyreis, M; Kiesslich, T; Mayr, C; Gaisberger, M; Ritter, M; Kerschbaum, HH; Jakab, M;
Cell Physiol Biochem. 2018; 50(4): 1460-1473.
Full papers/articles (Journal)
HDAC-Linked "Proliferative" miRNA Expression Pattern in Pancreatic Neuroendocrine Tumors.
Klieser, E; Urbas, R; Swierczynski, S; Stättner, S; Primavesi, F; Jäger, T; Mayr, C; Kiesslich, T; Fazio, PD; Helm, K; Neureiter, D;
Int J Mol Sci. 2018; 19(9):
Full papers/articles (Journal)
Miniaturization of the Clonogenic Assay Using Confluence Measurement.
Mayr, C; Beyreis, M; Dobias, H; Gaisberger, M; Pichler, M; Ritter, M; Jakab, M; Neureiter, D; Kiesslich, T;
Int J Mol Sci. 2018; 19(3):
Full papers/articles (Journal)
The histone methyltransferase G9a: a new therapeutic target in biliary tract cancer.
Mayr, C; Helm, K; Jakab, M; Ritter, M; Shrestha, R; Makaju, R; Wagner, A; Pichler, M; Beyreis, M; Staettner, S; Jaeger, T; Klieser, E; Kiesslich, T; Neureiter, D;
Hum Pathol. 2018; 72:117-126
Full papers/articles (Journal)
Histone deacetylases inhibition: a potential diagnostic and therapeutic target for cancers-reply.
Neureiter, D; Kiesslich, T;
Hum Pathol. 2018; 71: 167-168.
Letters
Update on the role and therapeutic potential of polycomb repressive complexes in (biliary tract) cancer.
Neureiter, D; Kiesslich, T; Ritter, M; Mayr, C;
Expert Opin Ther Targets. 2018; 22(1): 1-3.
Editorials
Thermographic real-time-monitoring of surgical radiofrequency and microwave ablation in a perfused porcine liver model.
Primavesi, F; Swierczynski, S; Klieser, E; Kiesslich, T; Jäger, T; Urbas, R; Hutter, J; Neureiter, D; Öfner, D; Stättner, S;
Oncol Lett. 2018; 15(3):2913-2920
Full papers/articles (Journal)
Endoscopic submucosal dissection (ESD) for anal high-grade intraepithelial neoplasia: a case report.
Wagner, A; Neureiter, D; Holzinger, J; Kiesslich, T; Klieser, E; Berr, F;
Z Gastroenterol. 2018; 56(5):495-498
Case Reports
Single-center implementation of endoscopic submucosal dissection (ESD) in the colorectum: Low recurrence rate after intention-to-treat ESD.
Wagner, A; Neureiter, D; Kiesslich, T; Wolkersdörfer, GW; Pleininger, T; Mayr, C; Dienhart, C; Yahagi, N; Oyama, T; Berr, F;
Dig Endosc. 2018; 30(3):354-363
Full papers/articles (Journal)
Pharmacological Inhibition of Class IIA HDACs by LMK-235 in Pancreatic Neuroendocrine Tumor Cells.
Wanek, J; Gaisberger, M; Beyreis, M; Mayr, C; Helm, K; Primavesi, F; Jäger, T; Di Fazio, P; Jakab, M; Wagner, A; Neureiter, D; Kiesslich, T;
Int J Mol Sci. 2018; 19(10):
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Insulin resistance and colon epithelial proliferation
Kedenko, L; Maybock, J; Kronberger, C; Kiesslich, T; Kedenko, I; Paulweber, B; Wolkersdorfer, G
DIABETOLOGIA. 2018; 61: S592-S592.
Abstracts (Journal)
2017
Journal Articles
In Vitro Cell Death Discrimination and Screening Method by Simple and Cost-Effective Viability Analysis.
Helm, K; Beyreis, M; Mayr, C; Ritter, M; Jakab, M; Kiesslich, T; Plaetzer, K;
Cell Physiol Biochem. 2017; 41(3): 1011-1019.
Full papers/articles (Journal)
Thoughts on investigational hedgehog pathway inhibitors for the treatment of cancer.
Jäger, T; Ocker, M; Kiesslich, T; Neureiter, E; Neureiter, D;
Expert Opin Investig Drugs. 2017; 26(2):133-136
Editorials
The H+/K+ ATPase Inhibitor SCH-28080 Inhibits Insulin Secretion and Induces Cell Death in INS-1E Rat Insulinoma Cells.
Jakab, M; Ketterl, N; Fürst, J; Beyreis, M; Kittl, M; Kiesslich, T; Hauser-Kronberger, C; Gaisberger, M; Ritter, M;
Cell Physiol Biochem. 2017; 43(3):1037-1051
Full papers/articles (Journal)
IMP2/IGF2BP2 expression, but not IMP1 and IMP3, predicts poor outcome in patients and high tumor growth rate in xenograft models of gallbladder cancer.
Kessler, SM; Lederer, E; Laggai, S; Golob-Schwarzl, N; Hosseini, K; Petzold, J; Schweiger, C; Reihs, R; Keil, M; Hoffmann, J; Mayr, C; Kiesslich, T; Pichler, M; Kim, KS; Rhee, H; Park, YN; Lax, S; Obrist, P; Kiemer, AK; Haybaeck, J;
Oncotarget. 2017; 8(52): 89736-89745.
Full papers/articles (Journal)
Comprehensive immunohistochemical analysis of histone deacetylases in pancreatic neuroendocrine tumors: HDAC5 as a predictor of poor clinical outcome.
Klieser, E; Urbas, R; Stättner, S; Primavesi, F; Jäger, T; Dinnewitzer, A; Mayr, C; Kiesslich, T; Holzmann, K; Di Fazio, P; Neureiter, D; Swierczynski, S;
Hum Pathol. 2017; 65: 41-52.
Full papers/articles (Journal)
Biliary tract cancer stem cells - translational options and challenges.
Mayr, C; Ocker, M; Ritter, M; Pichler, M; Neureiter, D; Kiesslich, T;
World J Gastroenterol. 2017; 23(14): 2470-2482.
Reviews
SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types.
Richtig, G; Aigelsreiter, A; Schwarzenbacher, D; Ress, AL; Adiprasito, JB; Stiegelbauer, V; Hoefler, G; Schauer, S; Kiesslich, T; Kornprat, P; Winder, T; Eisner, F; Gerger, A; Stoeger, H; Stauber, R; Lackner, C; Pichler, M;
PLoS One. 2017; 12(11): e0187814
Full papers/articles (Journal)
Reduced complication rates of percutaneous transhepatic biliary drainage with ultrasound guidance.
Wagner, A; Mayr, C; Kiesslich, T; Berr, F; Friesenbichler, P; Wolkersdörfer, GW;
J Clin Ultrasound. 2017; 45(7): 400-407.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
The effect of Napabucasin on cancer stem cells in biliary tract cancer
Beyreis, M; Helm, K; Dobias, H; Jakab, M; Ritter, M; Neureiter, D; Kiesslich, T; Mayr, C
ACTA PHYSIOL. 2017; 221: 252-252.
Abstracts (Journal)
In Vitro Cell Death Discrimination and Screening Method by Simple and Cost-Effective Viability Analysis
Helm, K; Beyreis, M; Mayr, C; Ritter, M; Jakab, M; Kiesslich, T; Platzer, K
ACTA PHYSIOL. 2017; 221: 176-176.
Abstracts (Journal)
The histone-modification complex G9a and its role in biliary tract cancer/cholangiocarcinoma
Helm, K; Mayr, C; Beyreis, M; Ritter, M; Jakab, M; Klieser, E; Kiesslich, T; Neureiter, D
ACTA PHYSIOL. 2017; 221: 252-252.
Abstracts (Journal)
Expression pattern of histone deacetylases in gastrointestinal stromal tumors compared to clinic-pathological data
Klieser, E; Schmidt, J; Jäger, T; Mayr, C; Urbas, R; Kiesslich, T; Neureiter, D
Der Pathologe. 2017; 38(Supp. 1):S133-S133.-101. Jahrestagung der Deutschen Gesellschaft für Pathologie e.V.; 22.-24.06.2017; Erlangen.
Abstracts (Journal)
The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in binary tract cancer cells
Mayr, C; Wagner, A; Loffelberger, M; Bruckner, D; Jakab, M; Berr, F; Fazio, P; Ocker, M; Neureiters, D; Pichler, M; Kiesslich, T
ACTA PHYSIOL. 2017; 221: 250-252.
Abstracts (Journal)
Newspaper/magazine articles
Krebsstammzellen beim Melanom – von der Definition zur Therapie
Mayr, C; Neureiter, D; Kiesslich, T
JATROS Dermatologie & Plastische Chirurgie. 2017. 1: 10-13.
2016
Journal Articles
Methylsulfonyl Zn phthalocyanine: A polyvalent and powerful hydrophobic photosensitizer with a wide spectrum of photodynamic applications.
İşci, Ü; Beyreis, M; Tortik, N; Topal, SZ; Glueck, M; Ahsen, V; Dumoulin, F; Kiesslich, T; Plaetzer, K;
Photodiagnosis Photodyn Ther. 2016; 13:40-47
Full papers/articles (Journal)
Reasons for Journal Impact Factor Changes: Influence of Changing Source Items.
Kiesslich, T; Weineck, SB; Koelblinger, D;
PLoS One. 2016; 11(4): e0154199
Full papers/articles (Journal)
Back to the start: Evaluation of prognostic markers in gastrointestinal stromal tumors.
Klieser, E; Pichelstorfer, M; Weyland, D; Kemmerling, R; Swierczynski, S; Dinnewitzer, A; Jäger, T; Kiesslich, T; Neureiter, D; Illig, R;
Mol Clin Oncol. 2016; 4(5): 763-773.
Full papers/articles (Journal)
Differential role of Hedgehog signaling in human pancreatic (patho-) physiology: An up to date review.
Klieser, E; Swierczynski, S; Mayr, C; Jäger, T; Schmidt, J; Neureiter, D; Kiesslich, T; Illig, R;
World J Gastrointest Pathophysiol. 2016; 7(2): 199-210.
Reviews
Deregulated MicroRNAs in Biliary Tract Cancer: Functional Targets and Potential Biomarkers.
Mayr, C; Beyreis, M; Wagner, A; Pichler, M; Neureiter, D; Kiesslich, T;
Biomed Res Int. 2016; 2016:4805270
Reviews
The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells.
Mayr, C; Wagner, A; Loeffelberger, M; Bruckner, D; Jakab, M; Berr, F; Di Fazio, P; Ocker, M; Neureiter, D; Pichler, M; Kiesslich, T;
Oncotarget. 2016; 7(1): 745-758.
Full papers/articles (Journal)
Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells
Pehserl, AM; Ress, AL; Stanzer, S; Resel, M; Karbiener, M; Stadelmeyer, E; Stiegelbauer, V; Gerger, A; Mayr, C; Scheideler, M; Hutterer, GC; Bauernhofer, T; Kiesslich, T; Pichler, M
INT J MOL SCI. 2016; 17(12): 2011
Full papers/articles (Journal)
Current Insights into Long Non-Coding RNAs in Renal Cell Carcinoma
Seles, M; Hutterer, GC; Kiesslich, T; Pummer, K; Berindan-Neagoe, I; Perakis, S; Schwarzenbacher, D; Stotz, M; Gerger, A; Pichler, M
INT J MOL SCI. 2016; 17(4):
Reviews
Relevance of MicroRNA200 Family and MicroRNA205 for Epithelial to Mesenchymal Transition and Clinical Outcome in Biliary Tract Cancer Patients.
Urbas, R; Mayr, C; Klieser, E; Fuereder, J; Bach, D; Stättner, S; Primavesi, F; Jaeger, T; Stanzer, S; Ress, AL; Löffelberger, M; Wagner, A; Berr, F; Ritter, M; Pichler, M; Neureiter, D; Kiesslich, T;
Int J Mol Sci. 2016; 17(12):
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Reasons for Journal Impact Factor Changes: Influence of Changing Source Items
Kiesslich, T; Weineck, SB; Kölblinger, D;
Paracelsus Science Get Together Abstractband 2016. 2016; 90-90.-Paracelsus Science Get Together 2016; 24.06.2016; Salzburg. (ISBN: 978-3-200-04641-2 )
Abstracts (Journal)
Association between miRNAs and HDACs in Pancreatic Neuroendocrine Tumors
Swierczynski, S; Klieser, E; Urbas, R; Stattner, S; Primavesi, F; Jager, T; Kiesslich, T; Kemmerling, R; Di Fazio, P; Neureiter, D
NEUROENDOCRINOLOGY. 2016; 103: 8-8.
Abstracts (Journal)
miRNA and HDAC expression in pancreatic neuroendocrine tumors.
Swierczynski, S; Klieser, E; Urbas, R; Stättner, S; Primavesi, F; Jäger, T; Kiesslich, T; Kemmerling, R; DiFazio, P; Neureiter, D
Abstracts
100. Jahrestagung der Deutschen Gesellschaft für Pathologie e.V. . 2016; 37(Issue 1 Supplement):97-97.-100. Jahrestagung der deutschen Gesellschaft für Pathologie; 19.5. -21.5.2016; Berlin.
Abstracts (Journal)
Unpublished conference presentations
The functional impact of cell volume regulation
Ritter, M; Gaisberger, M; Kiesslich, T; Jakab, M
SAAPCON 2016; 5th Biennal Conference of South Asian Association of Physiologists (SAAP) in conjunction with
2nd Annual Conference of the Physiological Society of Nepal (PSN); 10-12 November, 2016; Dhulikhel, Nepal. 2016.
Book chapters
Photodynamic Therapy.
Kiesslich, T; Plaetzer, K; Krammer, B;
In: Schwab, M(Ed.); editors(s). Encyclopedia of Cancer. in press(in press) : Berlin Heidelberg: Springer; p. 1-6. (ISBN: 978-3-642-27841-9)
2015
Journal Articles
The pan-deacetylase inhibitor panobinostat affects angiogenesis in hepatocellular carcinoma models via modulation of CTGF expression.
Gahr, S; Mayr, C; Kiesslich, T; Illig, R; Neureiter, D; Alinger, B; Ganslmayer, M; Wissniowski, T; Fazio, PD; Montalbano, R; Ficker, JH; Ocker, M; Quint, K;
Int J Oncol. 2015; 47(3):963-970
Full papers/articles (Journal)
Endoplasmic Reticulum Stress in Pancreatic Neuroendocrine Tumors is Linked to Clinicopathological Parameters and Possible Epigenetic Regulations.
Klieser, E; Illig, R; Státtner, S; Primavesi, F; Jáger, T; Swierczynski, S; Kiesslich, T; Kemmerling, R; Bollmann, C; DI Fazio, P; Neureiter, D;
Anticancer Res. 2015; 35(11):6127-6136
Full papers/articles (Journal)
Role of histone deacetylases in pancreas: Implications for pathogenesis and therapy.
Klieser, E; Swierczynski, S; Mayr, C; Schmidt, J; Neureiter, D; Kiesslich, T; Illig, R;
World J Gastrointest Oncol. 2015; 7(12): 473-483.
Reviews
Cytotoxic effects of chemokine receptor 4 inhibition by AMD3100 in biliary tract cancer cells: Potential drug synergism with gemcitabine.
Mayr, C; Neureiter, D; Pichler, M; Berr, F; Wagner, A; Kiesslich, T; Namberger, K;
Mol Med Rep. 2015; 12(2):2247-2252
Full papers/articles (Journal)
The role of polycomb repressive complexes in biliary tract cancer.
Mayr, C; Neureiter, D; Wagner, A; Pichler, M; Kiesslich, T;
Expert Opin Ther Targets. 2015; 19(3):363-375
Full papers/articles (Journal)
The green tea catechin epigallocatechin gallate induces cell cycle arrest and shows potential synergism with cisplatin in biliary tract cancer cells.
Mayr, C; Wagner, A; Neureiter, D; Pichler, M; Jakab, M; Illig, R; Berr, F; Kiesslich, T;
BMC Complement Altern Med. 2015; 15:194
Full papers/articles (Journal)
3-Deazaneplanocin A May Directly Target Putative Cancer Stem Cells in Biliary Tract Cancer.
Mayr, C; Wagner, A; Stoecklinger, A; Jakab, M; Illig, R; Berr, F; Pichler, M; DI Fazio, P; Ocker, M; Neureiter, D; Kiesslich, T;
Anticancer Res. 2015; 35(9): 4697-4705.
Full papers/articles (Journal)
How to establish endoscopic submucosal dissection in Western countries.
Oyama, T; Yahagi, N; Ponchon, T; Kiesslich, T; Berr, F;
World J Gastroenterol. 2015; 21(40): 11209-11220.
Reviews
MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients.
Ress, AL; Stiegelbauer, V; Winter, E; Schwarzenbacher, D; Kiesslich, T; Lax, S; Jahn, S; Deutsch, A; Bauernhofer, T; Ling, H; Samonigg, H; Gerger, A; Hoefler, G; Pichler, M;
Mol Carcinog. 2015; 54(11): 1442-1450.
Full papers/articles (Journal)
Molecular Targeted Therapies in Hepatocellular Carcinoma: Past, Present and Future.
Stotz, M; Gerger, A; Haybaeck, J; Kiesslich, T; Bullock, MD; Pichler, M;
Anticancer Res. 2015; 35(11): 5737-5744.
Reviews
Histone deacetylation meets miRNA: epigenetics and post-transcriptional regulation in cancer and chronic diseases.
Swierczynski, S; Klieser, E; Illig, R; Alinger-Scharinger, B; Kiesslich, T; Neureiter, D;
Expert Opin Biol Ther. 2015; 15(5):651-664
Full papers/articles (Journal)
Temoporfin improves efficacy of photodynamic therapy in advanced biliary tract carcinoma: A multicenter prospective phase II study.
Wagner, A; Denzer, UW; Neureiter, D; Kiesslich, T; Puespoeck, A; Rauws, EA; Emmanuel, K; Degenhardt, N; Frick, U; Beuers, U; Lohse, AW; Berr, F; Wolkersdörfer, GW;
Hepatology. 2015; 62(5): 1456-1465.
Full papers/articles (Journal)
Neoadjuvant Down-Sizing of Hilar Cholangiocarcinoma with Photodynamic Therapy-Long-Term Outcome of a Phase II Pilot Study.
Wagner, A; Wiedmann, M; Tannapfel, A; Mayr, C; Kiesslich, T; Wolkersdörfer, GW; Berr, F; Hauss, J; Witzigmann, H;
Int J Mol Sci. 2015; 16(11): 26619-26628.
Full papers/articles (Journal)
[Medical habilitation in German-speaking countries: Quantitative assessment of content and elaboration of habilitation guidelines].
Weineck, SB; Koelblinger, D; Kiesslich, T;
Chirurg. 2015; 86(4): 3-65.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Epidemiomlogical and clinic-pathological survey of patients with autoimmune diseases of the liver in Austrian Federal State Salzburg: Experience of a single center.
Illig, R; Klieser, E; Tränkenschuh, W; Kiesslich, T; Berr, F; Neureiter, D;
Abstracts. 2015; 140--Falk Syposium 197 - Autoimmune Diseases of the Liver; 08.-09.05.2015; Lissabon.
Abstracts (Journal)
HDACs meet neuroendocrine tumors of the pancreas
Klieser, E; Illig, R; Stättner, S; Primavesi, F; Jäger, T; Swierczynski, S; Alinger, B; Kiesslich, T; Kemmerling, R; DiFazio, P; Neureiter, D
PATHOLOGE . 2015; 36: 117-118.
Abstracts (Journal)
Treatment of biliary tract cancer cells with polycomb repressive complex 1 inhibitor PTC-209 reduces putative cancer stem cell population and causes cell cycle arrest
Mayr, C; Wagner, A; Jakab, M; Illig, R; Berr, F; Pichler, M; Di Fazio, P; Ocker, M; Neureiter, D; Kiesslich, T
ACTA PHYSIOL. 2015; 213: 148-148.
Abstracts (Journal)
DZNep directly targets putative cancer stem cells in biliary tract cancer cells by inhibition of polycomb repressive complex 2
Mayr, C; Wagner, A; Stoecklinger, A; Jakab, M; Illig, R; Berr, F; Pichler, M; Di Fazio, P; Ocker, M; Neureiter, D; Kiesslich, T
ACTA PHYSIOL. 2015; 213: 147-148.
Abstracts (Journal)
Back to the start! Evaluation of prognostic markers in GIST
Pichelstorfer, M; Klieser, E; Weyland, D; Kemmerling, R; Jäger, T; Kiesslich, T; Neureiter, D; Illig, R
PATHOLOGE . 2015; 36: 95-95.
Abstracts (Journal)
Combination of age, ABC-type and intratumoral
T-regulator cells are a negative prognostic factors for
primary extranodal diffuse large B-cell lymphoma
Tränkenschuh, W; Kemmerling, R; Alinger, B; Melchardt, T; Egle, A; Kiesslich, T; Neureiter, D
PATHOLOGE . 2015; 36: 110-110.
Abstracts (Journal)
Medizinische Habilitation im deutschsprachigen Raum: Quantitative Untersuchung zu Inhalt und Ausgestaltung der Habilitationsrichtlinien
Weineck, SB; Kölblinger, D; Kiesslich, T;
Paracelsus Science Get Together 2015. 2015; 77-77.-Paracelsus Science Get Together 2015; 03.07.2015; Nürnberg. (ISBN: 978-3-00-050043-5 )
Abstracts (Journal)
Newspaper/magazine articles
P190: DZNep directly targets putative cancer stem cells in biliary tract cancer cells by inhibition of polycomb repressive complex 2
Mayr, C; Stoecklinger, A; Wagner, A; Jakab, M; Illig, R; Berr, F; Pichler, M; DiFazio, P; Ocker, M; Neureiter, D; Kiesslich, T
Acta Physiologica. 2015. 213: 147-148.
Poster P67: Treatment of biliary tract cancer cells with polycomb repressive complex 1 inhibitor PTC-209 reduces putative cancer stem cell population and causes cell cycle arrest
Mayr, C; Wagner, A; Beyreis, M; Illig, R; Berr, F; Pichler, M; Di Fazio, P; Neureiter, D; Kiesslich, T
Z Gastroenterol. 2015. 53: p67-p67.
P191: Treatment of biliary tract cancer cells with polycomb repressive complex 1 inhibitor PTC-209 reduces putative cancer stem cell population and causes cell cycle arrest
Mayr, C; Wagner, A; Jakab, M; Illig, R; Berr, F; Pichler, M; DiFazio, P; Ocker, M; Neureiter, D; Kiesslich, T
Acta Physiologica. 2015. 213: 148-148.
Poster P66: Green tea catechin epigallocatechin gallate causes apoptosis and shows potential synergism with cisplatin in biliary tract cancer cells
Mayr, C; Wagner, A; Neureiter, D; Pichler, M; Ritter, M; Illig, R; Berr, F; Kiesslich, T
Z Gastroenterol. 2015. 53: P66-P66.
Poster p17: Endoscopic Submucosal Dissection (ESD) unter Tutoring durch Experten
Wagner, A; Neureiter, D; Kiesslich, T; Allgaier, H; Kleber, G; Ziachehabi, A; Heiler, K; Plamenig, D; Friesenbichler, P; Wolkersdörfer, GW; Lutz, M; Seifert, H; Anzinger, M; Uraoka, T; Toyonaga, T; Yahagi, N; Oyama, T; Berr, F
Z Gastroenterol. 2015. 53: p17-p17.
2014
Journal Articles
Untutored learning curve to establish endoscopic submucosal dissection on competence level.
Berr, F; Wagner, A; Kiesslich, T; Friesenbichler, P; Neureiter, D;
Digestion. 2014; 89(3):184-193
Full papers/articles (Journal)
Genetic polymorphisms at SIRT1 and FOXO1 are associated with carotid atherosclerosis in the SAPHIR cohort.
Kedenko, L; Lamina, C; Kedenko, I; Kollerits, B; Kiesslich, T; Iglseder, B; Kronenberg, F; Paulweber, B;
BMC Med Genet. 2014; 15:112
Full papers/articles (Journal)
Robust linear regression model of Ki-67 for mitotic rate in gastrointestinal stromal tumors.
Kemmerling, R; Weyland, D; Kiesslich, T; Illig, R; Klieser, E; Jäger, T; Dietze, O; Neureiter, D;
Oncol Lett. 2014; 7(3): 745-749.
Full papers/articles (Journal)
Real-time analysis of endogenous protoporphyrin IX fluorescence from δ-aminolevulinic acid and its derivatives reveals distinct time- and dose-dependent characteristics in vitro.
Kiesslich, T; Helander, L; Illig, R; Oberdanner, C; Wagner, A; Lettner, H; Jakab, M; Plaetzer, K;
J Biomed Opt. 2014; 19(8):085007
Full papers/articles (Journal)
Activated hedgehog pathway is a potential target for pharmacological intervention in biliary tract cancer.
Kiesslich, T; Mayr, C; Wachter, J; Bach, D; Fuereder, J; Wagner, A; Alinger, B; Pichler, M; Di Fazio, P; Ocker, M; Berr, F; Neureiter, D;
Mol Cell Biochem. 2014; 396(1-2):257-268
Full papers/articles (Journal)
Endoplasmatic reticulum stress in pancreatic neuroendocrine tumors
Klieser, E; Illig, R; Stättner, S; Primavesi, F; Jäger, T; Swierczynski, S; Kiesslich, T; Kemmerling, R; Di Fazio, P; Neureiter, D
PATHOLOGE . 2014; 35: 97-98.
Abstracts (Journal)
Epigenetics and pancreatic cancer: Pathophysiology and novel treatment aspects.
Neureiter, D; Jäger, T; Ocker, M; Kiesslich, T;
World J Gastroenterol. 2014; 20(24): 7830-7848.
Reviews
MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients.
Pichler, M; Ress, AL; Winter, E; Stiegelbauer, V; Karbiener, M; Schwarzenbacher, D; Scheideler, M; Ivan, C; Jahn, SW; Kiesslich, T; Gerger, A; Bauernhofer, T; Calin, GA; Hoefler, G;
Br J Cancer. 2014; 110(6): 1614-1621.
Full papers/articles (Journal)
miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor
Pichler, M; Winter, E; Ress, AL; Bauernhofer, T; Gerger, A; Kiesslich, T; Lax, S; Samonigg, H; Hoefler, G
J CLIN PATHOL. 2014; 67(3): 198-203.
Full papers/articles (Journal)
MicroRNAs associated with the efficacy of photodynamic therapy in biliary tract cancer cell lines.
Wagner, A; Mayr, C; Bach, D; Illig, R; Plaetzer, K; Berr, F; Pichler, M; Neureiter, D; Kiesslich, T;
Int J Mol Sci. 2014; 15(11):20134-20157
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Expression pattern of epithelial-mesenchymal-transition associated miRNAs in biliary tract cancer: a clinical and pathological approach.
Illig, R; Kiesslich, T; Kemmerling, R; Klieser, E; Berr, F; Neureiter, D;
Abstract-Band - Pathophysiology and Treatment of Cholangiocarcinoma. 2014; -Falk Workshop; 23.-24.01.2014; Tübingen.
Abstracts (Journal)
PhD ScientMed' – an interdisciplinary PhD curriculum for physicians and natural scientists
Kiesslich, T; Halilovic, M; Kainz, P; Kofler, B; Weineck, SB; Ritter, M;
Abstractband 18. Grazer Konferenz "Education for Medical Future". 2014; 70-71.-18. Grazer Konferenz "Education for Medical Future"; 03.-05.04.2014; Salzburg. (ISBN: 978-3-200-03700-7 )
Abstracts (Journal)
Time- and dose-dependent characteristics of endogenous protoporphyrin IX production from delta-aminolevulinic acid and its derivatives
Kiesslich, T; Helander, L; Illig, R; Oberdanner, C; Wagner, A; Lettner, H; Jakab, M; Plaetzer, K
ACTA PHYSIOL. 2014; 211: 172-172.
Abstracts (Journal)
Combined PhD and medical specialist training at the University Hospital Salzburg / Paracelsus Medical University
Kofler, B; Studnicka, M; Magometschnigg, H; Kainz, P; Halilovic, M; Weineck, SB; Ritter, M; Kiesslich, T; Resch, H;
Abstractband 18. Grazer Konferenz "Education for Medical Future". 2014; 49-50.-18. Grazer Konferenz "Education for Medical Future"; 03.-05.04.2014; Salzburg. (ISBN: 978-3-200-03700-7 )
Abstracts (Journal)
PRC2 inhibition may directly target putative cancer stem cells in biliary tract cancer cell lines.
Mayr, C; Wagner, A; Illig, R; Pichler, M; Berr, F; Neureiter, D; Kiesslich, T;
Pathophysiology and Treatment of Cholangiocarcinoma. 2014; -Falk Workshop; 23.-24.01.2014; Tübingen.
Abstracts (Journal)
PTEN INACTIVATION AND ALTERATION OF THE PI3K/AKT/mTOR PATHWAY IN BILIARY TRACT CANCER
Petzold, J; Lederer, E; Reihs, R; Ernst, C; Bettermann, K; Halbwedl, I; Lax, S; Park, YN; Kim, KS; Kiesslich, T; Pichler, M; Obrist, P; Haybaeck, J
ANTICANCER RES. 2014; 34(10): 5942-5943.
Abstracts (Journal)
KG 206: Improved efficacy of temoporfin photodynamic therapy in locally advanced biliary tract carcinoma: a multicenter prospective phase II study
Wagner, A; Denzer, UW; Neureiter, D; Kiesslich, T; Berr, F; Puspoeck, A; Emmanuel, K; Lohse, AW; Beuers, U; Rauws, EA; Degenhardt, N; Wolkersdörfer, GW;
Abstractband, Gastroenterologie, Viszeralchirurgie - Viszeralmedizin. 2014; -69. Jahrestagung der DGVS mit Sektion Endoskopie; 17.-20.09.2014; Leipzig.
Abstracts (Journal)
MicroRNAs associated with the efficacy of photodynamic therapy in biliary tract cancer cell lines.
Wagner, A; Mayr, C; Bach, D; Illig, R; Plaetzer, K; Berr, F; Neureiter, D; Kiesslich, T;
Abstract Band - Pathophysiology and Treatment of Cholangiocarcinoma. 2014; -Falk Workshop; 23.-24.01.2014; Tübingen.
Abstracts (Journal)
Book chapters
Histopathology of Early Mucosal Neoplasias: Morphologic Carcinogenesis in the GI Tract
Neureiter, D; Kiesslich, T
In: Berr, F; Oyama, T; Ponchon, T; Yahagi, N (Eds) editors(s). Early Neoplasias of the Gastrointestinal Tract. New York: Springer US; p. 19-33. (ISBN: 978-1-4614-8291-8)
Newspaper/magazine articles
KG 164: Epithelial-mesenchymal transition-associated microRNA expression pattern in human biliary tract cancer: a clinical and pathological approach
Ilig, R; Kiesslich, T; Kemmerling, R; Alinger, B; Klieser, E; Berr, F; Neureiter, D
Zeitschrift für Gastroenterologie. 2014. 52: KG164-KG164.
DZNep may directly target putative cancer stem cells in biliary tract cancer cells by inhibition of PRC2
Mayr, C; Wagner, A; Stöcklinger, A; Jakab, M; Illig, R; Pichler, M; Berr, F; Neureiter, D; Kiesslich, T
Zeitschrift für Gastroenterologie. 2014. 52: KG167-KG167.
Improved efficacy of temoporfin photodynamic therapy in locally advanced biliary tract carcinoma: a multicenter prospective phase II study
Wagner, A; Denzer, UW, Neureiter, D; Kiesslich, T; Berr, F; Puspoeck, A; Emmanuel, K; Lohse, AW; Beuers, U; Rauws, EA; Degenhardt, N; Wolkersdörfer, GW
Zeintschrift für Gastroenterologie. 2014. 52: KG206-KG206.
2013
Journal Articles
Low expression of the putative tumour suppressor spinophilin is associated with higher proliferative activity and poor prognosis in patients with hepatocellular carcinoma.
Aigelsreiter, A; Ress, AL; Bettermann, K; Schauer, S; Koller, K; Eisner, F; Kiesslich, T; Stojakovic, T; Samonigg, H; Kornprat, P; Lackner, C; Haybaeck, J; Pichler, M;
Br J Cancer. 2013; 108(9):1830-1837
Full papers/articles (Journal)
Comprehensive analysis of alterations in the miRNome in response to photodynamic treatment.
Bach, D; Fuereder, J; Karbiener, M; Scheideler, M; Ress, AL; Neureiter, D; Kemmerling, R; Dietze, O; Wiederstein, M; Berr, F; Plaetzer, K; Kiesslich, T; Pichler, M;
J Photochem Photobiol B. 2013; 120: 74-81.
Full papers/articles (Journal)
The pan-deacetylase inhibitor panobinostat modulates the expression of epithelial-mesenchymal transition markers in hepatocellular carcinoma models.
DI Fazio, P; Montalbano, R; Quint, K; Alinger, B; Kemmerling, R; Kiesslich, T; Ocker, M; Neureiter, D;
Oncol Lett. 2013; 5(1):127-134
Full papers/articles (Journal)
GERD-Barrett-Adenocarcinoma: Do We Have Suitable Prognostic and Predictive Molecular Markers?
Illig, R; Klieser, E; Kiesslich, T; Neureiter, D;
Gastroenterol Res Pract. 2013; 2013:643084
Full papers/articles (Journal)
A comprehensive tutorial on in vitro characterization of new photosensitizers for photodynamic antitumor therapy and photodynamic inactivation of microorganisms.
Kiesslich, T; Gollmer, A; Maisch, T; Berneburg, M; Plaetzer, K;
Biomed Res Int. 2013; 2013:840417
Reviews
Epigenetic control of epithelial-mesenchymal-transition in human cancer.
Kiesslich, T; Pichler, M; Neureiter, D;
Mol Clin Oncol. 2013; 1(1): 3-11.
Reviews
Apoptosis in cancer cells induced by photodynamic treatment - a methodological approach
Kiesslich, T; Tortik, N; Pichler, M; Neureiter, D; Plaetzer, K
J PORPHYR PHTHALOCYA. 2013; 17(3): 197-209.
Full papers/articles (Journal)
New applications of photodynamic therapy in biomedicine and biotechnology.
Plaetzer, K; Berneburg, M; Kiesslich, T; Maisch, T;
Biomed Res Int. 2013; 2013: 161362
Editorials
Hedgehog Signaling Pathway in Ovarian Cancer
Szkandera, J; Kiesslich, T; Haybaeck, J; Gerger, A; Pichler, M
INT J MOL SCI. 2013; 14(1): 1179-1196.
Reviews
Photodynamic therapy for hilar bile duct cancer: clinical evidence for improved tumoricidal tissue penetration by temoporfin.
Wagner, A; Kiesslich, T; Neureiter, D; Friesenbichler, P; Puespoek, A; Denzer, UW; Wolkersdörfer, GW; Emmanuel, K; Lohse, AW; Berr, F;
Photochem Photobiol Sci. 2013; 12(6):1065-1073
Full papers/articles (Journal)
Photosensitizer Adhered to Cell Culture Microplates Induces Phototoxicity in Carcinoma Cells.
Ziegler, V; Kiesslich, T; Krammer, B; Plaetzer, K;
Biomed Res Int. 2013; 2013:549498
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Reduced Expression of the Putative Tumour Suppressor Spinophilin Is an Adverse Prognostic Factor in Squamous Cell Carcinoma of the Head and Neck
Aigelsreiter, AM; Aigelsreiter, A; Wehrschuetz, M; Ress, A; Koller, K; Kiesslich, T; Schauer, S; Bauernhofer, T; Pichler, M
MODERN PATHOL. 2013; 26: 301A-301A.
Abstracts (Journal)
Reduced Expression of the Putative Tumour Suppressor Spinophilin Is an Adverse Prognostic Factor in Squamous Cell Carcinoma of the Head and Neck
Aigelsreiter, AM; Aigelsreiter, A; Wehrschuetz, M; Ress, A; Koller, K; Kiesslich, T; Schauer, S; Bauernhofer, T; Pichler, M
LAB INVEST. 2013; 93: 301A-301A.
Abstracts (Journal)
Newspaper/magazine articles
P-008: Hedgehog signaling pathway and stem cell markers are linked with dysplastic changes of myelodysplastic syndrome
Alinger, B; Kemmerling, R; Klieser, E; Illig, R; Kiesslich, T; Neureiter, D
Leukemia Research. 2013. 37-S1: S26-S26.
Lymph Node Recovery after Gastrectomy for Gastric Adenocarcinoma is influenced by Clinical and Pathological Factors (ABS-295)
Illig, R; Klieser, E; Kiesslich, T; Jäger, T; Dietze, O; Neureiter, D;
Der Pathologe. 2013. 34, S1: 79-80.
Robust linear regression model of Ki-67 for determination of the mitotic rate in gastrointestinal stromal tumors (ABS-172)
Kemmerling, R; Weyland, D; Kiesslich, T; Jäger, T; Dietze, O; Neureiter; D;
Der Pathologe. 2013. 34, S1: 81-81.
Up-regulated Hedgehog Pathway as a Potential Novel Drug Target in Biliary Tract Cancer (ABS-171)
Kiesslich, T; Wachter, J; Bach, D; Fuereder, J; Alinger, B; Pichler, M; DiFazio, P; Ocker, M; Berr, F; Neureiter, D;
Der Pathologe. 2013. 34, S1: 122-122.
2012
Journal Articles
NEMO expression in human hepatocellular carcinoma and its association with clinical outcome.
Aigelsreiter, A; Haybaeck, J; Schauer, S; Kiesslich, T; Bettermann, K; Griessbacher, A; Stojakovic, T; Bauernhofer, T; Samonigg, H; Kornprat, P; Lackner, C; Pichler, M;
Hum Pathol. 2012; 43(7): 1012-1019.
Full papers/articles (Journal)
Genetic Polymorphisms of the Main Transcription Factors for Adiponectin Gene Promoter in Regulation of Adiponectin Levels: Association Analysis in Three European Cohorts
Kedenko, L; Lamina, C; Kiesslich, T; Kapur, K; Bergmann, S; Waterworth, D; Heid, IM; Wichmann, HE; Kedenko, I; Kronenberg, F; Paulweber, B
PLOS ONE. 2012; 7(12):
Full papers/articles (Journal)
Association of stem cell marker expression pattern and survival in human biliary tract cancer.
Kemmerling, R; Alinger, B; Dietze, O; Bösmüller, HC; Ocker, M; Wolkersdörfer, GW; Berr, F; Neureiter, D; Kiesslich, T;
Int J Oncol. 2012; 41(2):511-522
Full papers/articles (Journal)
Current status of therapeutic targeting of developmental signalling pathways in oncology.
Kiesslich, T; Berr, F; Alinger, B; Kemmerling, R; Pichler, M; Ocker, M; Neureiter, D;
Curr Pharm Biotechnol. 2012; 13(11):2184-2220
Reviews
Advances in targeting the Hedgehog signaling pathway in cancer therapy.
Kiesslich, T; Neureiter, D;
Expert Opin Ther Targets. 2012; 16(2):151-156
Editorials
Influence of five potential anticancer drugs on wnt pathway and cell survival in human biliary tract cancer cells.
Wachter, J; Neureiter, D; Alinger, B; Pichler, M; Fuereder, J; Oberdanner, C; Di Fazio, P; Ocker, M; Berr, F; Kiesslich, T;
Int J Biol Sci. 2012; 8(1):15-29
Full papers/articles (Journal)
Unpublished conference presentations
Epigenetic Regulation of Cancer Stem Cells
Kiesslich, T
9. Jahrestagung Deutsche Vereinte Gesellschaft für Klinische Chemie und Laboratoriumsmedizin; 26.-29.09.2012; Mannheim. 2012.
Book chapters
Photodynamic Therapy
Krammer, B; Kiesslich, T;
In: Manfred Schwab (Ed.) editors(s). in: Encyclopedia of Cancer (3rd edition). Berlin Heidelberg: Springer Berlin Heidelberg; p. 2876-2881. (ISBN: 978-3-642-16482-8)
2011
Journal Articles
Experimental endoscopic submucosal dissection training in a porcine model: learning experience of skilled Western endoscopists.
Berr, F; Ponchon, T; Neureiter, D; Kiesslich, T; Haringsma, J; Kaehler, GF; Schmoll, F; Messmann, H; Yahagi, N; Oyama, T;
Dig Endosc. 2011; 23(4): 281-289.
Full papers/articles (Journal)
Lipophilic rather than hydrophilic photosensitizers show strong adherence to standard cell culture microplates under cell-free conditions.
Engelhardt, V; Kiesslich, T; Berlanda, J; Hofbauer, S; Krammer, B; Plaetzer, K;
J Photochem Photobiol B. 2011; 103(3): 222-229.
Full papers/articles (Journal)
Myelodysplastic Syndrome and Histone Deacetylase Inhibitors: "To Be or Not to Be Acetylated"?
Stintzing, S; Kemmerling, R; Kiesslich, T; Alinger, B; Ocker, M; Neureiter, D
J BIOMED BIOTECHNOL. 2011; 2011: 214143
Reviews
MHC class II genotype- and MHC class I and II phenotype-related parameters in sporadic colorectal cancer.
Wolkersdörfer, T; Füssel, M; Kiesslich, T; Neureiter, D; Berr, F; Aust, D; Wolkersdörfer, GW;
Oncol Rep. 2011; 26(5):1165-1171
Full papers/articles (Journal)
2010
Journal Articles
Comparative in vitro study on the characteristics of different photosensitizers employed in PDT.
Berlanda, J; Kiesslich, T; Engelhardt, V; Krammer, B; Plaetzer, K;
J PHOTOCH PHOTOBIO B. 2010; 100(3): 173-180.
Full papers/articles (Journal)
Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition
Kiesslich, T; Alinger, B; Wolkersdorfer, GW; Ocker, M; Neureiter, D; Berr, F
INT J ONCOL. 2010; 36(1): 49-58.
Full papers/articles (Journal)
Uptake and phototoxicity of meso-tetrahydroxyphenyl chlorine are highly variable in human biliary tract cancer cell lines and correlate with markers of differentiation and proliferation
Kiesslich, T; Neureiter, D; Alinger, B; Jansky, GL; Berlanda, J; Mkrtchyan, V; Ocker, M; Plaetzer, K; Berr, F
PHOTOCH PHOTOBIO SCI. 2010; 9(5): 734-743.
Full papers/articles (Journal)
Advances in photodynamic therapy for the treatment of hilar biliary tract cancer
Kiesslich, T; Neureiter, D; Wolkersdorfer, GW; Plaetzer, K; Berr, F
FUTURE ONCOL. 2010; 6(12): 1925-1936.
Reviews
Gallengangskarzinom: Stellenwert der photodynamischen Therapie
Wolkersdörfer, G; Kiesslich, T; Neureiter, D; Berr, F;
Viszeralmedizin. 2010; 26: 194-198.
Full papers/articles (Journal)
Photodynamic Therapy in Proximal Bile Duct Cancer
Wolkersdorfer, GW; Kiesslich, T; Neureiter, D; Berr, F
VISZERALMEDIZIN. 2010; 26(3): 194-198.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Establishment of endoscopic submucosal dissection (ESD) in Europe: Experience with experimental training model.
Berr, F; Neureiter, D; Kiesslich, T; Wolkersdorfer, G; Schmoll, F
WIEN KLIN WOCHENSCHR. 2010; 122(17-18): A13-A13.
Abstracts (Journal)
Cellular phenotype and the photosensitizer uptake as determining factors of the Effectiveness of Photodynamic factors of the effectiveness of photodynamic therapy (PDT) bile duct cancer.
Kiesslich, T; Neureiter, D; Alinger, B; Hofbauer, S; Wachter, J; Ocker, M; Platzer, K; Berr, F
WIEN KLIN WOCHENSCHR. 2010; 122(17-18): A14-A14.
Abstracts (Journal)
HEDGEHOG SIGNALLING IS ACTIVE IN BILIARY TRACT CANCER AND AMENABLE TO PHARMACOLOGICAL INHIBITION
Kiesslich, T; Wachter, J; Alinger, B; Ocker, M; Neureiter, D; Berr, F
ANN ONCOL. 2010; 21: 47-47.
Abstracts (Journal)
HETEROGENEOUS EXPRESSION PATTERN OF HEDGEHOG SIGNALLING PATHWAY IN HEMATOPOIESIS OF MYELODYSPLASTIC SYNDROME
Neureiter, D; Kemmerling, R; Alinger, B; Kiesslich, T; Faber, V; Stocher, M; Pleyer, L; Greil, R; Dietz, O
HAEMATOL-HEMATOL J. 2010; 95: 375-375.
Abstracts (Journal)
Cytotoxic mechanisms of low molecular weight inhibitors of Wnt signaling in bile duct cancer cell lines.
Wachter, J; Alinger, B; Ocker, M; Hofbauer, S; Neureiter, D; Berr, F; Kiesslich, T
WIEN KLIN WOCHENSCHR. 2010; 122(17-18): A13-A14.
Abstracts (Journal)
2009
Journal Articles
Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation.
Alinger, B; Kiesslich, T; Datz, C; Aberger, F; Strasser, F; Berr, F; Dietze, O; Kaserer, K; Hauser-Kronberger, C;
VIRCHOWS ARCH. 2009; 454(4): 36-79.
Full papers/articles (Journal)
Photodynamic therapy for non-resectable perihilar cholangiocarcinoma.
Kiesslich, T; Wolkersdörfer, G; Neureiter, D; Salmhofer, H; Berr, F;
PHOTOCH PHOTOBIO SCI. 2009; 8(1): 2-30.
Full papers/articles (Journal)
Photophysics and photochemistry of photodynamic therapy: fundamental aspects
Plaetzer, K; Krammer, B; Berlanda, J; Berr, F; Kiesslich, T
LASER MED SCI. 2009; 24(2): 259-268.
Reviews
Conference papers, proceedings, abstracts
Protein expression profile in different nerve sheath tumor entities focused on tumor stem cell markers
Hauser-Kronberger, C; Rosch, S; Alinger, B; Santner, F; Kiesslich, T
VIRCHOWS ARCH. 2009; 455: 393-393.
Abstracts (Journal)
Monographs ( scientific books)
Photodynamic Therapy
Krammer, B; Kiesslich, T;
in: Encyclopedia of Cancer (2nd edition); Berlin Heidelberg: Springer Berlin Heidelberg; 2009. pp. 2327-2331. (ISBN 978-3-540-36847-2)
2008
Journal Articles
Lokale Tumorablation beim Cholangiokarzinom: Photodynamische Therapie
Berr, F; Kiesslich, T; Wolkersdörfer, G
Journal für gastroenterologische und hepatologische Erkrankungen. 2008; 1(6): 7-10.
Reviews
Conference papers, proceedings, abstracts
DEVELOPMENTAL SIGNALLING PATHWAYS (HEDGEHOG, WNT, NOTCH) IN HUMAN CHOLANGIOCARCINOMA CELL LINES: EXPRESSION ANALYSIS AND PHARMACOLOGICAL INHIBITION
Kiesslich, T; Alinger, B; Wolkersdoerfer, G; Neureiter, D; Berr, F
ANN ONCOL. 2008; 19: 53-53.
Abstracts (Journal)
TEMOPORFIN IMPROVES TUMORICIDAL EFFICACY OF PHOTODYNAMIC THERAPY (PDT) FOR BILE DUCT CANCER
Wolkersdoerfer, G; Emmanuel, K; Denzer, U; Puespoek, A; Neureiter, D; Kiesslich, T; Lohse, AW; Berr, F
ANN ONCOL. 2008; 19: 176-177.
Abstracts (Journal)
2007
Journal Articles
Comparative characterization of the efficiency and cellular pharmacokinetics of Foscan-(R) and Foslip (R)-based photodynamic treatment in human biliary tract cancer cell lines
Kiesslich, T; Berlanda, J; Plaetzer, K; Krammer, B; Berr, F
PHOTOCH PHOTOBIO SCI. 2007; 6(6): 619-627.
Full papers/articles (Journal)
2006
Journal Articles
Characterization of apoptosis induced by photodynamic treatment with hypericin in A431 human epidermoid carcinoma cells.
Berlanda, J; Kiesslich, T; Oberdanner, CB; Obermair, FJ; Krammer, B; Plaetzer, K;
J Environ Pathol Toxicol Oncol. 2006; 25(1-2): 173-188.
Full papers/articles (Journal)
Antiproliferative Properties of Padma Lax and Its Components Ginger and Elecampane
Hofbauer, S; Kainz, V; Golser, L; Klappacher, M; Kiesslich, T; Heidegger, W; Krammer, B; Hermann, A; Weiger, TM
FORSCH KOMPLEMENTMED. 2006; 13: 18-22.
Full papers/articles (Journal)
Cellular mechanisms and prospective applications of hypericin in photodynamic therapy.
Kiesslich, T; Krammer, B; Plaetzer, K;
Curr Med Chem. 2006; 13(18): 2189-2204.
Full papers/articles (Journal)
2005
Journal Articles
Differential effects of glucose deprivation on the cellular sensitivity towards photodynamic treatment-based production of reactive oxygen species and apoptosis-induction.
Kiesslich, T; Plaetzer, K; Oberdanner, CB; Berlanda, J; Obermair, FJ; Krammer, B;
FEBS Lett. 2005; 579(1): 185-190.
Full papers/articles (Journal)
Photodynamic treatment with fractionated light decreases production of reactive oxygen species and cytotoxicity in vitro via regeneration of glutathione.
Oberdanner, CB; Plaetzer, K; Kiesslich, T; Krammer, B;
Photochem Photobiol. 2005; 81(3): 609-613.
Full papers/articles (Journal)
Apoptosis following photodynamic tumor therapy: induction, mechanisms and detection.
Plaetzer, K; Kiesslich, T; Oberdanner, CB; Krammer, B;
Curr Pharm Des. 2005; 11(9): 1151-1165.
Full papers/articles (Journal)
2003
Journal Articles
Fast and reliable determination of intracellular ATP from cells cultured in 96-well microplates.
Kiesslich, T; Benno Oberdanner, C; Krammer, B; Plaetzer, K;
J Biochem Biophys Methods. 2003; 57(3): 247-251.
Full papers/articles (Journal)
2002
Journal Articles
Glucose is required to maintain high ATP-levels for the energy-utilizing steps during PDT-induced apoptosis.
Oberdanner, CB; Kiesslich, T; Krammer, B; Plaetzer, K;
Photochem Photobiol. 2002; 76(6): 695-703.
Full papers/articles (Journal)
Characterization of the cell death modes and the associated changes in cellular energy supply in response to AlPcS4-PDT.
Plaetzer, K; Kiesslich, T; Krammer, B; Hammerl, P;
Photochem Photobiol Sci. 2002; 1(3): 172-177.
Full papers/articles (Journal)