ECKSTEIN FELIX
Institute of Anatomy and Cell Biology
Publications
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Researcher Profile
711 Publications
2023
Journal Articles
Which risk factors determine cartilage thickness and composition change in radiographically normal knees? – data from the osteoarthritis initiative
Eckstein, F; Maschek, S; Culvenor, A; Sharma, L; Roemer, FW; Duda, G.N.; Wirth, W;
Osteoarthritis and Cartilage Open. 2023;
Full papers/articles (Journal)
Worsening of Articular Tissue Damage as Defined by Semi-Quantitative MRI Is Associated With Concurrent Quantitative Cartilage Loss Over 24 Months.
Roemer, F; Maschek, S; Wisser, A; Guermazi, A; Hunter, D; Eckstein, F; Wirth, W;
Cartilage. 2023; 14(1):39-47
Full papers/articles (Journal)
Evaluation of S201086/GLPG1972, an ADAMTS-5 inhibitor, for the treatment of knee osteoarthritis in ROCCELLA: a phase 2 randomized clinical trial.
Schnitzer, T; Pueyo, M; Deckx, H; van der Aar, E; Bernard, K; Hatch, S; van der Stoep, M; Grankov, S; Phung, D; Imbert, O; Chimits, D; Muller, K; Hochberg, MC; Bliddal, H; Wirth, W; Eckstein, F; Conaghan, PG;
Osteoarthritis Cartilage. 2023;
Full papers/articles (Journal)
Association between knee magnetic resonance imaging markers and knee symptoms over 6-9 years in young adults.
Singh, A; Venn, A; Blizzard, L; March, L; Eckstein, F; Jones, G; Wirth, W; Cicuttini, F; Ding, C; Antony, B;
Rheumatology (Oxford). 2023;
Full papers/articles (Journal)
Test-retest precision and longitudinal cartilage thickness loss in the IMI-APPROACH cohort.
Wirth, W; Maschek, S; Marijnissen, ACA; Lalande, A; Blanco, FJ; Berenbaum, F; van de Stadt, LA; Kloppenburg, M; Haugen, IK; Ladel, CH; Bacardit, J; Wisser, A; Eckstein, F; Roemer, FW; Lafeber, FPJG; Weinans, HH; Jansen, M;
Osteoarthritis Cartilage. 2023; 31(2): 238-248.
Full papers/articles (Journal)
2022
Journal Articles
Response letter to the Editor.
Conaghan, PG; Guehring, H; Moreau, F; Daelken, B; Ladel, C; Guenther, O; Reinstrup Bihlet, A; Wirth, W; Eckstein, F; Hochberg, M;
Semin Arthritis Rheum. 2022; 52:151839
Author reply
Detection of Differences in Longitudinal Cartilage Thickness Loss Using a Deep-Learning Automated Segmentation Algorithm: Data From the Foundation for the National Institutes of Health Biomarkers Study of the Osteoarthritis Initiative.
Eckstein, F; Chaudhari, AS; Fuerst, D; Gaisberger, M; Kemnitz, J; Baumgartner, CF; Konukoglu, E; Hunter, DJ; Wirth, W;
Arthritis Care Res (Hoboken). 2022; 74(6): 929-936.
Full papers/articles (Journal)
Association of Superficial Cartilage Transverse Relaxation Time With Osteoarthritis Disease Progression: Data From the Foundation for the National Institutes of Health Biomarker Study of the Osteoarthritis Initiative.
Fuerst, D; Wirth, W; Gaisberger, M; Hunter, DJ; Eckstein, F;
Arthritis Care Res (Hoboken). 2022; 74(11):1888-1893
Full papers/articles (Journal)
Multivariable Modeling of Biomarker Data From the Phase I Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium.
Hunter, DJ; Deveza, LA; Collins, JE; Losina, E; Nevitt, MC; Roemer, FW; Guermazi, A; Bowes, MA; Dam, EB; Eckstein, F; Lynch, JA; Katz, JN; Kwoh, CK; Hoffmann, S; Kraus, VB;
Arthritis Care Res (Hoboken). 2022; 74(7):1142-1153
Full papers/articles (Journal)
Local MRI-based measures of thigh adipose tissue derived from fully automated deep convolutional neural network-based segmentation show a comparable responsiveness to bidirectional change in body weight as from quality controlled manual segmentation.
Kemnitz, J; Steidle-Kloc, E; Wirth, W; Fuerst, D; Wisser, A; Eder, SK; Eckstein, F;
Ann Anat. 2022; 240: 151866
Full papers/articles (Journal)
Changes in Body Weight and Knee Pain in Adults With Knee Osteoarthritis Three-and-a-Half Years After Completing Diet and Exercise Interventions: Follow-Up Study for a Single-Blind, Single-Center, Randomized Controlled Trial.
Messier, SP; Newman, JJ; Scarlett, MJ; Mihalko, SL; Miller, GD; Nicklas, BJ; DeVita, P; Hunter, DJ; Lyles, MF; Eckstein, F; Guermazi, A; Loeser, RF; Beavers, DP;
Arthritis Care Res (Hoboken). 2022; 74(4):607-616
Full papers/articles (Journal)
Longitudinal Relationship Between Tibiofemoral Contact Stress at Baseline and Worsening of Knee Pain Over 84 Months in the Multicenter Osteoarthritis Study.
Rabe, KG; Stockman, TJ; Kern, AM; Wirth, W; Eckstein, F; Sharma, L; Lynch, JA; Nevitt, M; Anderson, DD; Segal, NA;
Am J Phys Med Rehabil. 2022; 101(8):726-732
Full papers/articles (Journal)
Presence of Magnetic Resonance Imaging-Defined Inflammation Particularly in Overweight and Obese Women Increases Risk of Radiographic Knee Osteoarthritis: The POMA Study.
Roemer, FW; Guermazi, A; Hannon, MJ; Fujii, T; Omoumi, P; Hunter, DJ; Eckstein, F; Kwoh, CK;
Arthritis Care Res (Hoboken). 2022; 74(8):1391-1398
Full papers/articles (Journal)
Structural tissue damage and 24-month progression of semi-quantitative MRI biomarkers of knee osteoarthritis in the IMI-APPROACH cohort.
Roemer, FW; Jansen, M; Marijnissen, ACA; Guermazi, A; Heiss, R; Maschek, S; Lalande, A; Blanco, FJ; Berenbaum, F; van de Stadt, LA; Kloppenburg, M; Haugen, IK; Ladel, CH; Bacardit, J; Wisser, A; Eckstein, F; Lafeber, FPJG; Weinans, HH; Wirth, W;
BMC Musculoskelet Disord. 2022; 23(1): 988
Full papers/articles (Journal)
Meniscus position and size in knees with versus without structural knee osteoarthritis progression: data from the osteoarthritis initiative.
Sharma, K; Eckstein, F; Wirth, W; Emmanuel, K
Skeletal Radiol. 2022; 51(5):997-1006
Full papers/articles (Journal)
Association between osteoarthritis-related serum biochemical markers over 11 years and knee MRI-based imaging biomarkers in middle-aged adults.
Singh, A; Venn, A; Blizzard, L; Jones, G; Burgess, J; Parameswaran, V; Cicuttini, F; March, L; Eckstein, F; Wirth, W; Ding, C; Antony, B;
Osteoarthritis Cartilage. 2022; 30(5): 756-764.
Full papers/articles (Journal)
Responsiveness of Subcutaneous Fat, Intermuscular Fat, and Muscle Anatomical Cross-Sectional Area of the Thigh to Longitudinal Body Weight Loss and Gain: Data from the Osteoarthritis Initiative (OAI).
Steidle-Kloc, E; Dannhauer, T; Wirth, W; Eckstein, F;
Cells Tissues Organs. 2022; 211(5):555-564
Full papers/articles (Journal)
Quantitative measurement of cartilage morphology in osteoarthritis: current knowledge and future directions.
Wirth, W; Ladel, C; Maschek, S; Wisser, A; Eckstein, F; Roemer, F;
Skeletal Radiol. 2022;
Reviews
MRI-based semi-quantitative grading allows to specifically select knees with subsequent cartilage thickness loss.
Wirth, W; Maschek, S; Wisser, A; Guermazi, A; Hunter, DJ; Kwoh, CK; Nevitt, MC; Eckstein, F; Roemer, FW;
Arthritis Care Res (Hoboken). 2022;
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
ASSOCIATION BETWEEN KNEE MR IMAGING MARKERS AND KNEE SYMPTOMS OVER 7 YEARS IN YOUNG ADULTS
Antony, B; Venn, A; Blizzard, L; March, L; Cicuttini, F; Eckstein, F; Jones, G; Ding, C; Singh, A
ANN RHEUM DIS. 2022; 81: 320-320.
Abstracts (Journal)
PREDICTORS OF LONGITUDINAL MRI-BASED CARTILAGE THICKNESS CHANGE IN THE OBSERVATIONAL MULTICENTER APPROACH COHORT
Maschek, S; Roemer, FW; Marijnissen, AC; Jansen, M; Wisser, A; Lafeber, F; Lalande, A; Weinans, HH; Blanco, FJ; Berenbaum, F; van de Stadt, LA; Kloppenburg, M; Haugen, IK; Ladel, CH; Bacardit, J; Eckstein, F; Wirth, W
OSTEOARTHR CARTILAGE. 2022; 30: S46-S47.
Abstracts (Journal)
DO AUTOMATED, U-NET-BASED CARTILAGE SEGMENTATIONS FROM MRI BENEFIT FROM MANUAL QUALITY CONTROL AND CORRECTION? DATA FROM THE IMI-APPROACH PROJECT
Maschek, S; Wisser, A; Jansen, M; Marijnissen, AC; Lafeber, F; Lalande, A; Weinans, H; Blanco, FJ Berenbaum, F; Kloppenburg, M; Haugen, IK; Ladel, CH; Roemer, FW; Eckstein, F; Wirth, W;
Osteoarthritis Imaging. 2022; 2(Supplement 1):100016--16th International Workshop on Osteoarthritis Imaging; 06.-08.07.2022; Tokyo.
Abstracts (Journal)
MRI-ASSESSED INCREASE IN GRADE AND EXTENT OF SUBREGIONAL INVOLVEMENT OF MENISCAL DAMAGE AND BONE MARROW LESIONS DEFINED SEMI-QUANTITATIVELY ARE ASSOCIATED WITH CONCURRENT QUANTITATIVELY-DEFINED CARTILAGE THICKNESS LOSS: THE FNIH BIOMARKERS CONSORTIUM STUDY
Roemer, F; Maschek, S; Wisser, A; Guermazi, A; Hunter, D; Eckstein, F; Wirth, W
OSTEOARTHR CARTILAGE. 2022; 30: S263-S264.
Abstracts (Journal)
NON-CARTILAGINOUS STRUCTURAL JOINT DAMAGE AS ASSESSED BY MRI INCREASES RATES OF QUANTITATIVE MRI-DETECTED CARTILAGE THICKNESS LOSS OVER 24 MONTHS: THE APPROACH STUDY
Roemer, F; Wisser, A; Maschek, S; Guermazi, A; Eckstein, F; Marijnissen, AK; Jansen, M; Lafeber, F; Lalande, A; Weinans, H; Blanco, F; Berenbaum, F; Kloppenburg, M; Haugen, IK; Wirth, W
OSTEOARTHR CARTILAGE. 2022; 30: S266-S267.
Abstracts (Journal)
MENISCAL DAMAGE AND BONE MARROW LESIONS ARE ASSOCIATED WITH CONCURRENT QUANTITATIVELY DEFINED CARTILAGE THICKNESS LOSS OVER TWO YEARS: THE FNIH BIOMARKERS CONSORTIUM STUDY
Roemer, FW; Maschek, S; Wisser, W; Guermazi, A; Hunter, DJ; Eckstein, F; Wirth, W;
Osteoarthritis Imaging. 2022; 2(Supplement 1):100056--16th International Workshop on Osteoarthritis Imaging; 06.-08.07.2022; Tokyo.
Abstracts (Journal)
NON-CHONDRAL MULTI-TISSUE PATHOLOGY AS ASSESSED BY MRI INCREASES RATES OF QUANTITATIVE MRI-DEFINED CARTILAGE THICKNESS LOSS OVER 24 MONTHS: THE APPROACH STUDY
Roemer; FW; Wisser, A; Maschek, S; Guermazi, A; Eckstein, F; Marijnissen, A; Jansen, M; Lafeber, F; Lalande, A; Weinans, H; Blanco, FJ; Berenbaum, F; Kloppenburg, M; Haugen, IK; Ladel, C; Heiss, R; Bacardit, J; Vande Stadt, LA; Wirth, W;
Osteoarthritis Imaging. 2022; 2(Supplement 1):100031--16th International Workshop on Osteoarthritis Imaging; 06.-08.07.2022; Tokyo.
Abstracts (Journal)
MULTI‐TISSUE ASSESSMENT AND 24‐MONTH PROGRESSION OF SEMI‐QUANTITATIVE MRI BIOMARKERS OF KNEE OSTEOARTHRITIS IN THE IMI‐APPROACH COHORT
Roemer, FW; Wisser, A; Maschek, S; Guermazi, A; Eckstein, F; Marijnissen, AC; Jansen, MP; Lafeber, FP; Lalande, A; Weinans, H; Blanco, FJ; Berenbaum, F; Kloppenburg, M; Haugen, IK; , C; Ladel; Heiss, R; Bacardit, J; Vande Stadt, LA; Wirth, W;
Osteoarthritis Imaging. 2022; 2(Supplement 1):100045--16th International Workshop on Osteoarthritis Imaging; 06.-08.07.2022; Tokyo.
Abstracts (Journal)
LONGITUDINAL CHANGE IN QUANTITATIVE 3D MEDIAL MENISCUS MEASURES PRECEDING TO AND CONCURRENT WITH STRUCTURAL KNEE OSTEOARTHRITIS PROGRESSION - DATA FROM THE OAI FNIH BIOMARKER STUDY
Sharma, K; Maschek, S; Eckstein, F; Wirth, W
OSTEOARTHR CARTILAGE. 2022; 30: S287-S289.
Abstracts (Journal)
ASSOCIATION BETWEEN KNEE MR IMAGING MARKERS AND KNEE SYMPTOMS OVER 7 YEARS IN YOUNG ADULTS
Singh, A; Venn, A; Blizzard, L; March, L; Cicuttini, F; Eckstein, F; Jones, G; Ding, CH; Antony, B
INTERN MED J. 2022; 52: 20-21.
Abstracts (Journal)
MRI-BASED SEMI-QUANTITATIVE ASSESSMENT ALLOWS TARGETED SELECTION OF KNEES WITH ACCELERATED QUANTITATIVE CARTILAGE THICKNESS LOSS: DATA FROM THE OAI FNIH BIOMARKER CONSORTIUM
Wirth, W; Maschek, S; Wisser, A; Guermazi, A; Hunter, DJ; Eckstein, F; Roemer, FW
OSTEOARTHR CARTILAGE. 2022; 30: S264-S265.
Abstracts (Journal)
PREDICTORS OF LONGITUDINAL MRI-BASED CARTILAGE THICKNESS CHANGE IN THE OBSERVATIONAL MULTICENTER APPROACH COHORT
Wirth, W; Wisser, A; Maschek, S; Marijnissen, AC; Lafeber, FP; Lalande, A; Weinans, H; Blanco, FJ; Berenbaum, F; Kloppenburg, M; van de Stadt, LA; Haugen, IK; Ladel, CH; Bacardit, J; Roemer, FW; Eckstein, F; Jansen, MP;
Osteoarthritis Imaging. 2022; 2(Supplement 1):100020--16th International Workshop on Osteoarthritis Imaging; 06.-08.07.2022; Tokyo.
Abstracts (Journal)
AGREEMENT AND SENSITIVITY TO BETWEEN-GROUP DIFFERENCES OF U-NET-BASED, AUTOMATED CARTILAGE T2 ANALYSES FROM MULTI-ECHO SPIN ECHO MRI - DATA FROM THE OA-BIO PROJECT
Wirth, W; Wisser, A; Roemer, FW; Berenbaum, F; Eckstein, F; Maschek, S
OSTEOARTHR CARTILAGE. 2022; 30: S82-S84.
Abstracts (Journal)
ASSOCIATION OF SEMIQUANTITATIVE MRI-BASED MEASURES OF KNEE CARTILAGE WITH INCREASED CARTILAGE LOSS IN KNEES AT ELEVATED RISK OF DEVELOPING OSTEOARTHRITIS - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Wisser, A; Roemer, F; Maschek, S; Eckstein, F; Guermazi, A; Wirth, W
OSTEOARTHR CARTILAGE. 2022; 30: S272-S274.
Abstracts (Journal)
AGREEMENT AND SENSITIVITY TO BETWEEN-GROUP DIFFERENCES OF U-NET-BASED, AUTOMATED CARTILAGE T2 ANALYSES - DATA FROM THE OA-BIO PROJECT
Wisser, A; Roemer, FW; Berenbaum, F; Eckstein, F; Maschek, S; Wirth, W;
Osteoarthritis Imaging. 2022; 2(Supplement 1):100015--16th International Workshop on Osteoarthritis Imaging; 06.-08.07.2022; Tokyo.
Abstracts (Journal)
2021
Journal Articles
Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study.
Eckstein, F; Hochberg, MC; Guehring, H; Moreau, F; Ona, V; Bihlet, AR; Byrjalsen, I; Andersen, JR; Daelken, B; Guenther, O; Ladel, C; Michaelis, M; Conaghan, PG;
Ann Rheum Dis. 2021; 80(8):1062-1069
Full papers/articles (Journal)
Osteoarthritis year in review 2020: imaging.
Eckstein, F; Wirth, W; Culvenor, A;
Osteoarthritis Cartilage. 2021; 29(2):170-179
Reviews
Impact of Diabetes Mellitus on Knee Osteoarthritis Pain and Physical and Mental Status: Data From the Osteoarthritis Initiative.
Eitner, A; Culvenor, AG; Wirth, W; Schaible, HG; Eckstein, F;
Arthritis Care Res (Hoboken). 2021; 73(4):540-548
Full papers/articles (Journal)
Endogenous anandamide and self-reported pain are significantly reduced after a 2-week multimodal treatment with and without radon therapy in patients with knee osteoarthritis: a pilot study.
Gaisberger, M; Fuchs, J; Riedl, M; Edtinger, S; Reischl, R; Grasmann, G; Hölzl, B; Landauer, F; Dobias, H; Eckstein, F; Offenbächer, M; Ritter, M; Winklmayr, M;
Int J Biometeorol. 2021; 65(7):1151-1160
Full papers/articles (Journal)
The effects of sprifermin on symptoms and structure in a subgroup at risk of progression in the FORWARD knee osteoarthritis trial.
Guehring, H; Moreau, F; Daelken, B; Ladel, C; Guenther, O; Bihlet, AR; Wirth, W; Eckstein, F; Hochberg, M; Conaghan, PG;
Semin Arthritis Rheum. 2021; 51(2): 450-456.
Full papers/articles (Journal)
Changes in Cartilage Thickness and Denuded Bone Area after Knee Joint Distraction and High Tibial Osteotomy-Post-Hoc Analyses of Two Randomized Controlled Trials
Jansen, MP; Maschek, S; van Heerwaarden, RJ; Mastbergen, SC; Wirth, W; Lafeber, FPJG; Eckstein, F
J CLIN MED. 2021; 10(2): 368
Full papers/articles (Journal)
Comparison between 2D radiographic weight-bearing joint space width and 3D MRI non-weight-bearing cartilage thickness measures in the knee using non-weight-bearing 2D and 3D CT as an intermediary.
Jansen, MP; Mastbergen, SC; Eckstein, F; van Heerwaarden, RJ; Spruijt, S; Lafeber, FPJG;
Ther Adv Chronic Dis. 2021; 12: 20406223211037868
Full papers/articles (Journal)
Effects of unloader bracing on clinical outcomes and articular cartilage regeneration following microfracture of isolated chondral defects: a randomized trial.
Konopka, JA; Finlay, AK; Eckstein, F; Dragoo, JL;
Knee Surg Sports Traumatol Arthrosc. 2021; 29(9):2889-2898
Full papers/articles (Journal)
Efficacy and cost-effectiveness of Stem Cell injections for symptomatic relief and strUctural improvement in people with Tibiofemoral knee OsteoaRthritis: protocol for a randomised placebo-controlled trial (the SCUlpTOR trial)
Liu, XQ; Robbins, S; Wang, X; Virk, S; Schuck, K; Deveza, LA; Oo, WM; Carmichael, K; Antony, B; Eckstein, F; Wirth, W; Little, C; Linklater, J; Harris, A; Humphries, D; OxxxConnell, R; Heller, G; Buttel, T; Lohmander, S; Ding, CH; Hunter, DJ
BMJ OPEN. 2021; 11(11): e056382
Full papers/articles (Journal)
Is Laminar Cartilage Composition as Determined by T2 Relaxometry Associated with Incident and Worsening of Cartilage or Bone Marrow Abnormalities?
Roemer, FW; Eckstein, F; Duda, G; Guermazi, A; Maschek, S; Sharma, L; Wirth, W;
Cartilage. 2021; 13(1_suppl):757S-766S
Full papers/articles (Journal)
Changes in Medial Meniscal Three-Dimensional Position and Morphology As Predictors of Knee Replacement in Rapidly Progressing Knee Osteoarthritis: Data From the Osteoarthritis Initiative.
Roth, M; Emmanuel, K; Wirth, W; Kwoh, CK; Hunter, DJ; Hannon, MJ; Eckstein, F;
Arthritis Care Res (Hoboken). 2021; 73(7):1031-1037
Full papers/articles (Journal)
Early anterior cruciate ligament reconstruction does not affect 5 year change in knee cartilage thickness: secondary analysis of a randomized clinical trial.
Wirth, W; Eckstein, F; Culvenor, AG; Hudelmaier, MI; Stefan Lohmander, L; Frobell, RB;
Osteoarthritis Cartilage. 2021; 29(4): 518-526.
Full papers/articles (Journal)
Accuracy and longitudinal reproducibility of quantitative femorotibial cartilage measures derived from automated U-Net-based segmentation of two different MRI contrasts: data from the osteoarthritis initiative healthy reference cohort.
Wirth, W; Eckstein, F; Kemnitz, J; Baumgartner, CF; Konukoglu, E; Fuerst, D; Chaudhari, AS;
MAGMA. 2021; 34(3):337-354
Full papers/articles (Journal)
Longitudinal Change in Knee Cartilage Thickness and Function in Subjects with and without MRI-Diagnosed Cartilage Damage.
Wisser, A; Lapper, A; Roemer, F; Fuerst, D; Maschek, S; Wirth, W; Duda, GN; Eckstein, F;
Cartilage. 2021; 13(1_suppl):685S-693S
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
TEST-RETEST RELIABILITY AND SMALLEST DETECTABLE CHANGE (SDC) OF MRI-BASED CARTILAGE THICKNESS ANALYSIS IN A LARGE MULTICENTER RANDOMIZED CONTROLLED CLINICAL TRIAL OF KNEE OSTEOARTHRITIS
Eckstein, F; Bernard, K; Deckx, H; Imbert, O; Lalande, A; Wisser, A; Maschek, S; Wirth, W
OSTEOARTHR CARTILAGE. 2021; 29: S327-S328.
Abstracts (Journal)
EFFECT OF TRAINING SET SAMPLE SIZE ON THE AGREEMENT, ACCURACY, AND SENSITIVITY TO CHANGE OF AUTOMATED U-NET-BASED CARTILAGE THICKNESS ANALYSIS
Eckstein, F; Chaudhari, A; Baumgartner, CF; Konukoglu, E; Wisser, A; Furst, D; Wirth, W
OSTEOARTHR CARTILAGE. 2021; 29: S326-S327.
Abstracts (Journal)
CARTILAGE VOLUME, THICKNESS, AND SUBCHONDRAL BONE AREA MEASURES OBTAINED FROM MULTIPLE ECHO SPIN ECHO (MESE) T2 IMAGES VS VALIDATED CARTILAGE MORPHOMETRY
Furst, D; Wirth, W; Chaudhari, A; Eckstein, F
OSTEOARTHR CARTILAGE. 2021; 29: S318-S319.
Abstracts (Journal)
SUPERFICIAL CARTILAGE TRANSVERSE RELAXATION TIME (T2) IS ASSOCIATED WITH FUTURE OSTEOARTHRITIS DISEASE PROGRESSION - DATA FROM THE FNIH BIOMARKER STUDY OF THE OSTEOARTHRITIS INITIATIVE (OAI).
Furst, D; Wirth, W; Gaisberger, M; Hunter, DJ; Eckstein, F
OSTEOARTHR CARTILAGE. 2021; 29: S314-S316.
Abstracts (Journal)
3D CONTOUR REGISTRATION REVEALS THAT LOCATION-INDEPENDENT CARTILAGE THICKNESS SCORES AND REGIONAL PATTERNS DIFFER BETWEEN EARLY AND LATE FOLLOW-UP PERIODS AFTER ANTERIOR CRUCIATE LIGAMENT (ACL) RUPTURE
Furst, D; Wirth, W; Wisser, A; Gaisberger, M; Frobell, R; Lohmander, S; Eckstein, F
OSTEOARTHR CARTILAGE. 2021; 29: S316-S317.
Abstracts (Journal)
A DEEP-LEARNING-BASED TECHNIQUE FOR THE QUANTITATIVE ANALYSIS OF FEMOROTIBIAL OSTEOPHYTE AND BONE VOLUMES -DATA FROM THE OSTEOARTHRITIS INITIATIVE
Schachinger, JK; Maschek, S; Wisser, A; Furst, D; Chaudhari, AS; Kemnitz, J; Baumgartner, CF; Konukoglu, E; Eckstein, F; Wirth, W
OSTEOARTHR CARTILAGE. 2021; 29: S328-S329.
Abstracts (Journal)
EFFICACY AND SAFETY OF S201086/GLPG1972, AN ADAMTS-5 INHIBITOR, IN PATIENTS WITH KNEE OSTEOARTHRITIS: ROCCELLA, A 52-WEEK, RANDOMIZED, DOUBLE-BLIND, DOSE-RANGING PHASE 2 STUDY
Schnitzer, TJ; Pueyo, M; Deckx, H; van der Aar, E; Bernard, K; Hatch, S; van der Stoep, M; Grankov, S; Phung, D; Imbert, O; Chimits, D; Muller, K; Hochberg, M; Bliddal, H; Eckstein, F; Conaghan, P
OSTEOARTHR CARTILAGE. 2021; 29: S264-S265.
Abstracts (Journal)
LONGITUDINAL CHANGE IN FUNCTIONAL PERFORMANCE MEASURES PRIOR AND CONCURRENT TO CLINICALLY IMPORTANT WORSENING OR IMPROVEMENT IN WOMAC KNEE FUNCTIONeDATA FROM THE OAI
Steidle-Kloc, E; Sattler, T; Ruhdorfer, A; Wirth, W; Galler, S; Eckstein, F
OSTEOARTHR CARTILAGE. 2021; 29: S15-S15.
Abstracts (Journal)
AGREEMENT AND ACCURACY OF FEMOROTIBIAL CARTILAGE MORPHOMETRY IN RADIOGRAPHIC KNEE OA USING DIFFERENT TRAINING SETS FOR AUTOMATEDDEEP LEARNING SEGMENTATION - COMPARISON BETWEEN FLASH AND DESS MRI
Wirth, W; Chaudhari, AS; Kemnitz, J; Baumgartner, CF; Konukoglu, E; Furst, D; Eckstein, F
OSTEOARTHR CARTILAGE. 2021; 29: S334-S334.
Abstracts (Journal)
FULLY AUTOMATED CARTILAGE SEGMENTATION OF LATE STAGE OSTEOARTHRITIS (KLG4) KNEES USING DEEP LEARNING WITH U-NET ARCHITECTURES - MODEL SPECIFICITY IS IMPORTANT
Wisser, A; Wirth, W; Chaudhari, A; Fuerst, D; Baumgartner, C; Konukoglu, E; Eckstein, F
OSTEOARTHR CARTILAGE. 2021; 29: S319-S320.
Abstracts (Journal)
2020
Journal Articles
Automated MRI assessment confirms cartilage thickness modification in patients with knee osteoarthritis: post-hoc analysis from a phase II sprifermin study.
Brett, A; Bowes, MA; Conaghan, PG; Ladel, C; Guehring, H; Moreau, F; Eckstein, F;
Osteoarthritis Cartilage. 2020; 28(11):1432-1436
Full papers/articles (Journal)
Longitudinal changes in location-specific cartilage thickness and T2 relaxation-times after posterior cruciate ligament reconstruction for isolated and multiligament injury.
Culvenor, AG; Wirth, W; Boeth, H; Duda, GN; Eckstein, F;
Clin Biomech (Bristol, Avon). 2020; 79:104935
Full papers/articles (Journal)
Association of baseline and change in tibial and femoral cartilage thickness and development of widespread full-thickness cartilage loss in knee osteoarthritis - data from the Osteoarthritis Initiative.
Dório, M; Hunter, DJ; Collins, JE; Asher, R; Eckstein, F; Guermazi, A; Roemer, FW; Deveza, LA;
Osteoarthritis Cartilage. 2020; 28(6): 811-818.
Full papers/articles (Journal)
Intra-articular sprifermin reduces cartilage loss in addition to increasing cartilage gain independent of location in the femorotibial joint: post-hoc analysis of a randomised, placebo-controlled phase II clinical trial.
Eckstein, F; Kraines, JL; Aydemir, A; Wirth, W; Maschek, S; Hochberg, MC;
Ann Rheum Dis. 2020; 79(4):-528.
Full papers/articles (Journal)
Layer-specific analysis of femorotibial cartilage t2 relaxation time based on registration of segmented double echo steady state (dess) to multi-echo-spin-echo (mese) images.
Fürst, D; Wirth, W; Chaudhari, A; Eckstein, F;
MAGMA. 2020; 33(6):819-828
Full papers/articles (Journal)
Imaging of OA - From disease modification to clinical utility.
Hayashi, D; Roemer, FW; Eckstein, F; Samuels, J; Guermazi, A;
Best Pract Res Clin Rheumatol. 2020; 34(6):101588
Reviews
Clinical evaluation of fully automated thigh muscle and adipose tissue segmentation using a U-Net deep learning architecture in context of osteoarthritic knee pain
Kemnitz, J; Baumgartner, CF; Eckstein, F; Chaudhari, A; Ruhdorfer, A; Wirth, W; Eder, SK; Konukoglu, E
MAGN RESON MATER PHY. 2020;
Full papers/articles (Journal)
Predicting knee replacement in participants eligible for disease-modifying osteoarthritis drug treatment with structural endpoints.
Kwoh, CK; Guerhing, H; Aydemir, A; Hannon, MJ; Eckstein, F; Hochberg, MC;
Osteoarthritis Cartilage. 2020; 28(6): 782-791.
Full papers/articles (Journal)
Association of infra-patellar fat pad size with age and body weight in children and adolescents.
Ladenhauf, HN; Schlattau, A; Burda, B; Wirth, W; Eckstein, F; Metzger, R; Ruhdorfer, A;
Ann Anat. 2020; 232:151533
Full papers/articles (Journal)
Association of body composition, physical activity and physical performance with knee cartilage thickness and bone area in young adults.
Meng, T; Antony, B; Venn, A; Eckstein, F; Cicuttini, F; March, L; Cross, M; Dwyer, T; Blizzard, L; Jones, G; Laslett, LL; Ding, C;
Rheumatology (Oxford). 2020; 59(7):1607-1616
Full papers/articles (Journal)
The effects of intensive dietary weight loss and exercise on gait in overweight and obese adults with knee osteoarthritis. The Intensive Diet and Exercise for Arthritis (IDEA) trial.
Messier, SP; Beavers, DP; Mihalko, SL; Miller, GD; Lyles, MF; Hunter, DJ; Carr, JJ; Eckstein, F; Guermazi, A; Loeser, RF; DeVita, P;
J Biomech. 2020; 98: 109477
Full papers/articles (Journal)
The effect of weight loss on the progression of meniscal extrusion and size in knee osteoarthritis: a post-hoc analysis of the Intensive Diet and Exercise for Arthritis (IDEA) trial.
Munugoda, IP; Beavers, DP; Wirth, W; Aitken, DA; Loeser, RF; Miller, GD; Lyles, M; Carr, JJ; Guermazi, A; Hunter, DJ; Messier, SP; Eckstein, F;
Osteoarthritis Cartilage. 2020; 28(4): 410-417.
Full papers/articles (Journal)
Frequencies of MRI-detected structural pathology in knees without radiographic OA and worsening over three years: How relevant is contralateral radiographic osteoarthritis?
Roemer, F; Eckstein, F; Duda, G; Guermazi, A; Maschek, S; Sharma, L; Wirth, W;
Osteoarthritis and Cartilage Open. 2020;
Full papers/articles (Journal)
Reduction in Thigh Muscle Strength Occurs Concurrently but Does Not Seem to Precede Incident Knee Pain in Women: Data From the Osteoarthritis Initiative Cohort.
Ruhdorfer, A; Wirth, W; Culvenor, AG; Eckstein, F;
Am J Phys Med Rehabil. 2020; 99(1):33-40
Full papers/articles (Journal)
Magnetic resonance imaging of human knee joint functionality under variable compressive in-situ loading and axis alignment.
Schad, P; Wollenweber, M; Thuring, J; Schock, J; Eschweiler, J; Palm, G; Radermacher, K; Eckstein, F; Prescher, A; Kuhl, C; Truhn, D; Nebelung, S
J MECH BEHAV BIOMED. 2020; 110: 103890
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
BASELINE CHARACTERISTICS OF THE STUDY POPULATION IN ROCCELLA, A PHASE 2 CLINICAL TRIAL EVALUATING THE EFFICACY AND THE SAFETY OF S201086/GLPG1972 IN PATIENTS WITH KNEE OSTEOARTHRITIS
Bernard, K; Grankov, S; Van der Stoep, M; Lalande, A; Imbert, O; Phung, D; Chimits, D; Muller, K; Van der Aar, E; Deckx, H; Pueyo, M; Eckstein, F
ANN RHEUM DIS. 2020; 79: 790-791.
Abstracts (Journal)
AN INTER-VENDOR STUDY OF SCAN-RESCAN AND LEFT-RIGHT KNEE ASYMMETRY VARIABILITY OF CARTILAGE T2 TRANSVERSE RELAXATION TIME AND MORPHOMETRY ASSESSED SIMULTANEOUSLY USING A SINGLE RAPID 4-MINUTE MRI SCAN
Chaudhari, AS; Lu, Q; Wisser, A; Wirth, W; Gold, GE; Hargreaves, BA; Eckstein, F
OSTEOARTHR CARTILAGE. 2020; 28: S269-S270.
Abstracts (Journal)
STUDY DESIGN OF ROCCELLA: A PHASE 2 CLINICAL TRIAL WITH A DISEASE-MODIFYING OSTEOARTHRITIS DRUG CANDIDATE GLPG1972/S201086
Deckx, H; Van der Aar, E; Van der Stoep, M; Wooning, M; Bernard, K; Grankov, S; Imbert, O; Pueyo, M; Eckstein, F
ANN RHEUM DIS. 2020; 79: 1733-1733.
Abstracts (Journal)
Long-term Efficacy and Safety of Intra-articular Sprifermin in Patients with Knee Osteoarthritis: Results from the 5-Year Forward Study
Eckstein, F; Hochberg, M; Guehring, H; Moreau, F; Ona, V; Bihlet, A; Byrjalsen, I; Andersen, J; Daelken, B; Guenther, O; Ladel, C; Michaelis, M; Conaghan, PG
ARTHRITIS RHEUMATOL. 2020; 72:
Abstracts (Journal)
LONG-TERM EFFICACY AND SAFETY OF INTRA-ARTICULAR SPRIFERMIN IN PATIENTS WITH KNEE OSTEOARTHRITIS: RESULTS FROM THE 5-YEAR FORWARD STUDY
Eckstein, F; Hochberg, M; Kraines, J; Guehring, H; Moreau, F; Ona, V; Bihlet, AR; Byrjalsen, I; Andersen, JR; Daelken, B; Guenther, O; Ladel, C; Michaelis, M; Conaghan, PG
OSTEOARTHR CARTILAGE. 2020; 28: S77-S78.
Abstracts (Journal)
VALIDATION OF LAYER SPECIFIC FEMOROTIBIAL CARTILAGE T2 RELAXATION TIME ANALYSIS BASED ON REGISTRATION OF SEGMENTED DOUBLE ECHO STEADY STATE TO MULTIPLE ECHO SPIN ECHO MRI IMAGES
Furst, D; Eckstein, F; Wirth, W
OSTEOARTHR CARTILAGE. 2020; 28: S286-S287.
Abstracts (Journal)
A SIMPLE COMBINATION CRITERIA INCREASE THE LIKELIHOOD TO OBSERVE CARTILAGE LOSS IN PATIENTS WITH OSTEOARTHRITIS
Imbert, O; Chimits, D; Guedj, M; Robert, V; Bernard, K; Lalande, A; Wirth, W; Eckstein, F; Pueyo, M
OSTEOARTHR CARTILAGE. 2020; 28: S387-S388.
Abstracts (Journal)
KNEE JOINT DISTRACTION IS MORE EFFICIENT IN RESTORING CARTILAGE THICKNESS THAN HIGH TIBIAL OSTEOTOMY IN PATIENTS WITH SEVERE KNEE OSTEOARTHRITIS
Jansen, M; Maschek, S; Van Heerwaarden, R; Mastbergen, S; Wirth, W; Lafeber, F; Eckstein, F
ANN RHEUM DIS. 2020; 79: 114-115.
Abstracts (Journal)
CARTILAGE STRUCTURE AND KNEE FUNCTION IN SUBJECTS WITH AND WITHOUT PRESENCE OF MRI-DIAGNOSED CARTILAGE DAMAGE, AND WITHOUT RISK FACTORS OF KNEE OSTEOARTHRITIS - A 4-YEAR LONGITUDINAL STUDY USING DATA FROM THE OSTEOARTHRITIS INITIATIVE
Lapper, A; Wisser, A; Roemer, F; Maschek, S; Wirth, W; Duda, G; Eckstein, F
OSTEOARTHR CARTILAGE. 2020; 28: S284-S285.
Abstracts (Journal)
DIAGNOSTIC PERFORMANCE OF REGION- AND LAYER-SPECIFIC CARTILAGE TRANSVERSE RELAXTION TIME (T2) IN PRE-RADIOGRAPHIC AND RADIOGRAPHIC KNEE OSTEOARTHRITIS - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Maschek, S; Eckstein, F; Wirth, W
OSTEOARTHR CARTILAGE. 2020; 28: S50-S51.
Abstracts (Journal)
CHANGES IN MEDIAL COMPARTMENT LOADING AND ARTICULAR CARTILAGE THICKNESS 24 MONTHS AFTER LIMB REALIGNMENT SURGERY IN THE OPERATIVE AND NON-OPERATIVE LIMBS
Moyer, R; Birmingham, T; Primeau, C; Eckstein, F; Wirth, W; Giffin, JR
OSTEOARTHR CARTILAGE. 2020; 28: S56-S56.
Abstracts (Journal)
DEPENDENCE OF WOMAC PAIN ON RADIOGRAPHIC KNEE OA STATUS, AGE, SEX, BODY MASS INDEX (BMI), RACE, AND CONTRALATERAL KNEE PAIN STATUS
Racher, V; Wirth, W; Zimmermann, G; Bathke, A; Eckstein, F
OSTEOARTHR CARTILAGE. 2020; 28: S141-S142.
Abstracts (Journal)
DO CARTILAGE LAMINAR COMPOSITIONAL CHANGES AS ASSESSED BY T2 RELAXOMETRY PREDICT INCIDENT AND WORSENING OF STRUCTURAL MORPHOLOGIC DAMAGE IN THE SAME PLATE 3 YEARS LATER?
Roemer, F; Eckstein, F; Duda, G; Guermazi, A; Maschek, S; Wirth, W
OSTEOARTHR CARTILAGE. 2020; 28: S258-S259.
Abstracts (Journal)
DO CARTILAGE LAMINAR COMPOSITIONAL CHANGES AS ASSESSED BY T2 RELAXOMETRY PREDICT INCIDENT AND WORSENING OF STRUCTURAL MORPHOLOGIC DAMAGE IN THE SAME PLATE 3 YEARS LATER?
Roemer, F; Eckstein, F; Duda, G; Maschek, S; Guermazi, A; Wirth, W
ANN RHEUM DIS. 2020; 79: 113-114.
Abstracts (Journal)
EFFECT OF CONTRALATERAL RADIOGRAPHIC DISEASE SEVERITY ON THE PREVALENCE AND PROGRESSION OF MRI-DEFINED STRUCTURAL PATHOLOGY IN KNEES WITHOUT ESTABLISHED OSTEOARTHRITIS
Roemer, FW; Eckstein, F; Guermazi, A; Duda, G; Maschek, S; Wirth, W
OSTEOARTHR CARTILAGE. 2020; 28: S283-S284.
Abstracts (Journal)
QUANTITATIVE MEASURES OF THE MEDIAL MENISCUS ARE ASSOCIATED WITH PROGRESSION OF KNEE OSTEOARTHRITIS DATA FROM THE FNIH BIOMARKER STUDY
Sharma, K; Wirth, W; Emmanuel, K; Maschek, S; Eckstein, F
OSTEOARTHR CARTILAGE. 2020; 28: S275-S275.
Abstracts (Journal)
LONGITUDINAL CHANGES IN SPECIFIC MUSCLE STRENGTH BUT NOT IN MUSCLE ANATOMICAL CROSS-SECTIONAL AREAS IS ASSOCIATED WITH CHANGE IN KNEE FUNCTION - DATA FROM THE OSTEOARTHRITIS INITIATIVE (OAI)
Steidle-Kloc, E; Sattler, T; Kemnitz, J; Ruhdorfer, A; Wirtg, W; Galler, S; Eckstein, F
OSTEOARTHR CARTILAGE. 2020; 28: S219-S220.
Abstracts (Journal)
STUDY DESIGN OF A PHASE 2 CLINICAL TRIAL WITH A DISEASE-MODIFYING OSTEOARTHRITIS DRUG CANDIDATE GLPG1972/S201086: THE ROCCELLA TRIAL
vanderAar, E; Deckx, H; Van der Stoep, M; Wooning, M; Bernard, K; Gtankov, S; Imbert, O; Pueyo, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2020; 28: S499-S500.
Abstracts (Journal)
ACCURACY AND REPEATABILITY OF AUTOMATED FEMOROTIBIAL CARTILAGE SEGMENTATION USING CONVOLUTIONAL NEURAL NETWORKS - DATA FROM THE OSTEOARTHRITIS INITIATIVE HEALTHY REFERENCE COHORT
Wirth, W; Kemnitz, J; Baumartner, CF; Konukoglu, E; Maschek, S; Eckstein, F; Chaudhari, A
OSTEOARTHR CARTILAGE. 2020; 28: S273-S274.
Abstracts (Journal)
IS PHYSICAL ACTIVITY ASSESSED WITH ACCELEROMETERS MORE SENSITIVE TO KNEE PAIN THAN CONVENTIONAL FUNCTIONAL PERFORMANCE TESTS? - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Wisser, A; Eckstein, F; Wirth, W
OSTEOARTHR CARTILAGE. 2020; 28: S28-S29.
Abstracts (Journal)
2019
Journal Articles
Association between changes in molecular biomarkers of cartilage matrix turnover and changes in knee articular cartilage: a longitudinal pilot study.
Boeth, H; Raffalt, PC; MacMahon, A; Poole, AR; Eckstein, F; Wirth, W; Buttgereit, F; Önnerfjord, P; Lorenzo, P; Klint, C; Pramhed, A; Duda, GN;
J Exp Orthop. 2019; 6(1): 19
Full papers/articles (Journal)
Moderate Physical Activity and Prevention of Cartilage Loss in People With Knee Osteoarthritis: Data From the Osteoarthritis Initiative.
Bricca, A; Wirth, W; Juhl, CB; Kemnitz, J; Hunter, DJ; Kwoh, CK; Eckstein, F; Culvenor, AG;
Arthritis Care Res (Hoboken). 2019; 71(2):218-226
Full papers/articles (Journal)
Loss of patellofemoral cartilage thickness over 5 years following ACL injury depends on the initial treatment strategy: results from the KANON trial.
Culvenor, AG; Eckstein, F; Wirth, W; Lohmander, LS; Frobell, R;
Br J Sports Med. 2019; 53(18): 1168-1173.
Full papers/articles (Journal)
Trajectories of femorotibial cartilage thickness among persons with or at risk of knee osteoarthritis: development of a prediction model to identify progressors.
Deveza, LA; Downie, A; Tamez-Peña, JG; Eckstein, F; Van Spil, WE; Hunter, DJ;
Osteoarthritis Cartilage. 2019; 27(2):257-265
Full papers/articles (Journal)
Cartilage loss in radiographically normal knees depends on radiographic status of the contralateral knee - data from the Osteoarthritis Initiative.
Eckstein, F; Maschek, S; Roemer, FW; Duda, GN; Sharma, L; Wirth, W;
Osteoarthritis Cartilage. 2019; 27(2):273-277
Full papers/articles (Journal)
Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial.
Hochberg, MC; Guermazi, A; Guehring, H; Aydemir, A; Wax, S; Fleuranceau-Morel, P; Reinstrup Bihlet, A; Byrjalsen, I; Ragnar Andersen, J; Eckstein, F;
JAMA. 2019; 322(14): 136-1370.
Full papers/articles (Journal)
Response of thigh muscle cross‐sectional area to 21‐days of bed rest with exercise and nutrition countermeasures
Liphardt, AM; Bolte, V; Eckstein, F; Wirth, W; Brüggemann, GP; Niehoff, A;
Translational Sports Medicine. 2019; 3: 93-106.
Full papers/articles (Journal)
Association of adiposity measures in childhood and adulthood with knee cartilage thickness, volume and bone area in young adults.
Meng, T; Venn, A; Eckstein, F; Wirth, W; Cicuttini, F; March, L; Dwyer, T; Cross, M; Laslett, LL; Jones, G; Ding, C; Antony, B;
Int J Obes (Lond). 2019; 43(7):1411-1421
Full papers/articles (Journal)
Effect of intensive diet and exercise on self-efficacy in overweight and obese adults with knee osteoarthritis: The IDEA randomized clinical trial.
Mihalko, SL; Cox, P; Beavers, DP; Miller, GD; Nicklas, BJ; Lyles, M; Hunter, DJ; Eckstein, F; Guermazi, A; Loeser, RF; DeVita, P; Messier, SP;
Transl Behav Med. 2019; 9(2): 227-235.
Full papers/articles (Journal)
Validation of a novel blinding method for measuring postoperative knee articular cartilage using magnetic resonance imaging.
Moyer, R; Birmingham, T; Eckstein, F; Wirth, W; Maschek, S; Chronik, B; Giffin, JR;
MAGMA. 2019; 32(6):693-702
Full papers/articles (Journal)
Baseline structural tissue pathology is not strongly associated with longitudinal change in transverse relaxation time (T2) in knees without osteoarthritis.
Roemer, FW; Eckstein, F; Duda, GN; Guermazi, A; Maschek, S; Wirth, W;
Eur J Radiol. 2019; 118: -168.
Full papers/articles (Journal)
Is muscle strength in a painful limb affected by knee pain status of the contralateral limb? - Data from the Osteoarthritis Initiative.
Steidle-Kloc, E; Rabe, K; Eckstein, F; Wirth, W; Glass, NA; Segal, NA;
Ann Anat. 2019; 221: 68-75.
Full papers/articles (Journal)
The association of physical activity and depression in patients with, or at risk of, osteoarthritis is captured equally well by patient reported outcomes (PROs) and accelerometer measurements - Analyses of data from the Osteoarthritis Initiative.
van der Zee-Neuen, A; Wirth, W; Hösl, K; Osterbrink, J; Eckstein, F;
Semin Arthritis Rheum. 2019; 49(3):325-330
Full papers/articles (Journal)
Radiographically normal knees with contralateral joint space narrowing display greater change in cartilage transverse relaxation time than those with normal contralateral knees: a model of early OA? - data from the Osteoarthritis Initiative (OAI).
Wirth, W; Maschek, S; Roemer, FW; Sharma, L; Duda, GN; Eckstein, F;
Osteoarthritis Cartilage. 2019; 27(11): 1663-1668.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Confirmation of Manual Cartilage Segmentation Findings by Automated Segmentation: Retrospective Analysis of MRI Images from a Sprifermin Phase II Study
Brett, A; Bowes, MA; Conaghan, PG; Ladel, C; Kraines, J; Guehring, H; Moreau, F; Eckstein, F
ARTHRITIS RHEUMATOL. 2019; 71:
Abstracts (Journal)
MRI DATA FROM THE SPRIFERMIN PHASE II FORWARD STUDY: CONFIRMATION OF MANUAL CARTILAGE SEGMENTATION FINDINGS BY AUTOMATED SEGMENTATION
Brett, A; Bowes, MA; Conaghan, PG; Ladel, C; Kraines, J; Guhring, H; Moreau, F; Eckstein, F
ANN RHEUM DIS. 2019; 78: 1421-1422.
Abstracts (Journal)
RELATIONSHIP OF KNEE ADDUCTION AND FLEXION MOMENTS DURING GAIT WITH MEDIAL COMPARTMENT CARTILAGE THICKNESS 9 YEARS FOLLOWING POSTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Brisson, NM; Agres, AN; Jung, T; Culvenor, AG; Wirth, W; Eckstein, F; Duda, GN
OSTEOARTHR CARTILAGE. 2019; 27: S141-S142.
Abstracts (Journal)
SPATIAL DISTRIBUTION OF LONGITUDINAL CARTILAGE THICKNESS CHANGE IN ANTERIOR AND POSTERIOR CRUCIATE LIGAMENT INJURY COMPARED TO HEALTHY ATHLETIC CONTROLS
Culvenor, A; Wirth, W; Frobell, R; Lohmander, S; Duda, G; Boeth, H; Eckstein, F
OSTEOARTHR CARTILAGE. 2019; 27: S55-S56.
Abstracts (Journal)
CAN IMAGING MONITOR/DEMONSTRATE TREATMENT RESPONSE IN OA?
Eckstein, F;
ANN RHEUM DIS. 2019; 78: 13-14.
Abstracts (Journal)
DISCRIMINATION OF FUTURE KNEE REPLACEMENT: IMAGING BIOMARKERS ARE AS STRONG AS PATIENT-REPORTED OUTCOMES AND FUNCTIONAL PERFORMANCE TESTS
Eckstein, F; Hannon, M; Wirth, W; Maschek, S; Guermazi, A; Roemer, F; Hunter, DJ; Kwoh, KC
OSTEOARTHR CARTILAGE. 2019; 27: S205-S206.
Abstracts (Journal)
INTERSITE COMPARISON AND TEST-RETEST RELIABILITY OF CARTILAGE THICKNESS AND COMPOSTIONAL ANALYSIS IN THE APPROACH STUDY - A 2-YEAR MULTICENTER EUROPEAN EXPLORATORY STUDY FOR PHENOTYPE CHARACTERIZATON OF KNEE OSTEOARTHRITIS
Eckstein, F; Maschek, S; Bay-Jensen, A; Boere, J; Hussaarts, L; Ladel, C; Lalande, A; Larkin, J; Loughlin, J; Mobasheri, A; Palozzi, L; Weinans, H; Lafeber, FP; Berenbaum, F; Soler, R; Blanco, FJ; Isaksen, T; Haugen, IH; Loef, M; Kloppenburg, M; Marijnissen, AC; van Helvoort, E; van Spil, WE; Roemer, F; Wirth, W
OSTEOARTHR CARTILAGE. 2019; 27: S326-S327.
Abstracts (Journal)
CARTILAGE THICKNESS MODIFICATION WITH SPRIFERMIN IN KNEE OSTEOARTHRITIS PATIENTS TRANSLATES INTO SYMPTOMATIC IMPROVEMENT OVER PLACEBO IN PATIENTS AT RISK OF FURTHER STRUCTURAL AND SYMPTOMATIC PROGRESSION: POST-HOC ANALYSIS OF THE PHASE II FORWARD TRIAL
Guhring, H; Kraines, J; Moreau, F; Daelken, B; Ladel, C; Wirth, W; Conaghan, PG; Eckstein, F; Hochberg, M
ANN RHEUM DIS. 2019; 78: 70-71.
Abstracts (Journal)
CLINICAL VALIDATION OF FULLY AUTOMATED SEGMENTATION OF THIGH MUSCLE AND ADIPOSE TISSUE CROSS SECTIONAL AREAS USING MACHING LEARNING WITH A CONVOLUTIONAL NEURAL NETWORK
Kemnitz, J; Baumgartner, CF; Ruhdorfer, A; Wirth, W; Eckstein, F; Eder, SK; Konukoglu, E
OSTEOARTHR CARTILAGE. 2019; 27: S383-S384.
Abstracts (Journal)
IMPACT OF CONTRALATERAL RADIOGRAPHIC STATUS ON LONGITUDINAL CHANGE OF CARTILAGE TRANSVERSE RELAXATION TIME (T2) IN RADIOGRAPHICALLY NORMAL KNEES, A MODEL OF EARLY OA? - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Maschek, S; Wirth, W; Roemer, F; Duda, GN; Sharma, L; Eckstein, F
OSTEOARTHR CARTILAGE. 2019; 27: S328-S328.
Abstracts (Journal)
ASSOCIATION OF BODY COMPOSITION, PHYSICAL ACTIVITY AND PHYSICAL PERFORMANCE WITH KNEE CARTILAGE THICKNESS AND SUBCHONDRAL BONE AREA IN YOUNG ADULTS
Meng, T; Antony, B; Venn, A; Eckstein, F; Cicuttini, F; March, L; Cross, M; Dwyer, T; Jones, G; Laslett, L; Ding, C
OSTEOPOROSIS INT. 2019; 30: S410-S411.
Abstracts (Journal)
ASSOCIATION OF BODY COMPOSITION, PHYSICAL ACTIVITY AND PHYSICAL PERFORMANCE WITH KNEE CARTILAGE THICKNESS AND SUBCHONDRAL BONE AREA IN YOUNG ADULTS
Meng, T; Antony, B; Venn, A; Eckstein, F; Cicuttini, F; March, L; Cross, M; Dwyer, T; Jones, G; Laslett, L; Ding, CH
ANN RHEUM DIS. 2019; 78: 1039-1039.
Abstracts (Journal)
ASSOCIATION OF BODY COMPOSITION, PHYSICAL ACTIVITY AND PHYSICAL PERFORMANCE WITH KNEE CARTILAGE THICKNESS AND SUBCHONDRAL BONE AREA IN YOUNG ADULTS
Meng, T; Venn, A; Eckstein, F; Cicuttini, F; March, L; Dwyer, T; Cross, M; Laslett, LL; Jones, G; Antony, B; Ding, C
OSTEOARTHR CARTILAGE. 2019; 27: S252-S253.
Abstracts (Journal)
DO BODY MASS INDEX AND KNEE OSTEOARTHRITIS STATUS AFFECT MENISCAL EXTRUSION AND SIZE?
Munugoda, IP; Aitken, DA; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2019; 27: S368-S369.
Abstracts (Journal)
DO BODY MASS INDEX AND KNEE OSTEOARTHRITIS STATUS AFFECT MENISCAL EXTRUSION AND SIZE?
Munugoda, IP; Aitken, DA; Wirth, WW; Eckstein, F;
OSTEOPOROSIS INT. 2019; 30: S601-S601.
Abstracts (Journal)
THE EFFECT OF WEIGHT LOSS ON THE PROGRESSION OF MENISCAL EXTRUSION AND SIZE IN KNEE OSTEOARTHRITIS: A POST-HOC ANALYSIS OF THE INTENSIVE DIET AND EXERCISE FOR ARTHRITIS (IDEA) TRIAL
Munugoda, IP; Beavers, D; Wirth, W; Aitken, DA; Guermazi, A; Hunter, DJ; Messier, SP; Eckstein, F
OSTEOARTHR CARTILAGE. 2019; 27: S29-S30.
Abstracts (Journal)
FACTORS THAT DETERMINE FUNCTIONAL PERFORMANCE MEASURES IN ASYMPTOMATIC ADULTS WITHOUT KNEE OSTEOARTHRITIS - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Petersohn, S; Wisser, A; Culvenor, A; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2019; 27: S206-S207.
Abstracts (Journal)
DOES RADIOGRAPHIC KNEE OA STATUS IMPACT AGE-RELATED REDUCTION OF THIGH MUSCLE SPECIFIC STRENGTH - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Shakya, R; Kemnitz, J; Wirth, W; Maschek, S; Shrestha, R; Duda, GN; Eckstein, F
OSTEOARTHR CARTILAGE. 2019; 27: S468-S469.
Abstracts (Journal)
NO ASSOCIATION BETWEEN LOCAL LEVELS OF MOLECULAR BIOMARKERS AND KNEE CARTILAGE VOLUMES EARLY AFTER ANTERIOR CRUCIATE LIGAMENT INJURY
Struglics, A; Larsson, S; Eckstein, F; Wirth, W; Lohmander, LS; Frobell, R
OSTEOARTHR CARTILAGE. 2019; 27: S70-S71.
Abstracts (Journal)
THE ASSOCIATION OF PHYSICAL ACTIVITY AND DEPRESSION IN PATIENTS WITH OR AT RISK OF OSTEOARTHRITIS IS CAPTURED EQUALLY WELL BY PATIENT REPORTED OUTCOMES AND ACCELEROMETERS
van der Zee-Neuen, A; Wirth, W; Osterbrink, J; Hosl, K; Eckstein, F
OSTEOARTHR CARTILAGE. 2019; 27: S246-S247.
Abstracts (Journal)
CARTILAGE THICKNESS LOSS CORRELATES TO UTE-T2*EARLY AFTER ACL RECONSTRUCTION
Williams, A; Eckstein, F; Wirth, W; Chu, CR
OSTEOARTHR CARTILAGE. 2019; 27: S328-S329.
Abstracts (Journal)
STRUCTURAL PROGRESSOR THRESHOLDS OF FEMOROTIBIAL CARTILAGE CHANGE OVER 1 TO 4-YEARS FOR DIFFERENT MRI ORIENTATIONS AND CONTRASTS - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Wirth, W; Maschek, S; Ladel, C; Guehring, H; Michaelis, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2019; 27: S315-S316.
Abstracts (Journal)
PROGRESSOR RATES OF FEMOROTIBIAL CARTILAGE LOSS STRATIFIED BY RADIOGRAPHIC DISEASE STAGE, 1 TO 4-YEAR OBSERVATION INTERVALS, AND MRI PROTOCOLS - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Wirth, W; Maschek, S; Ladel, C; Guehring, H; Michaelis, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2019; 27: S53-S54.
Abstracts (Journal)
SENSITIVITY OF VARIOUS FUNCTIONAL PERFORMANCE MEASURES TO KNEE PAIN - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Wisser, A; Petersohn, S; Culvenor, A; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2019; 27: S74-S75.
Abstracts (Journal)
2018
Journal Articles
Five-minute knee MRI for simultaneous morphometry and T
Chaudhari, AS; Black, MS; Eijgenraam, S; Wirth, W; Maschek, S; Sveinsson, B; Eckstein, F; Oei, EHG; Gold, GE; Hargreaves, BA;
J Magn Reson Imaging. 2018; 47(5):1328-1341
Full papers/articles (Journal)
Is local or central adiposity more strongly associated with incident knee osteoarthritis than the body mass index in men or women?
Culvenor, AG; Felson, DT; Wirth, W; Dannhauer, T; Eckstein, F
OSTEOARTHR CARTILAGE. 2018; 26(8): 1033-1037.
Full papers/articles (Journal)
Brief Report: Loss of Muscle Strength Prior to Knee Replacement: A Question of Anatomic Cross-Sectional Area or Specific Strength?
Culvenor, AG; Hamler, FC; Kemnitz, J; Wirth, W; Eckstein, F;
Arthritis Rheumatol. 2018; 70(2):222-229
Full papers/articles (Journal)
Knee extensor muscle weakness and radiographic knee osteoarthritis progression.
Dellisola, A; Wirth, W; Steultjens, M; Eckstein, F; Culvenor, AG;
Acta Orthop. 2018; 89(4): 406-411.
Full papers/articles (Journal)
Transpedicular Approach on a Novel Spine Simulator: A Validation Study.
Fürst, D; Hollensteiner, M; Gabauer, S; Esterer, B; Trieb, K; Eckstein, F; Schrempf, A;
J Surg Educ. 2018; 75(4):1127-1134
Full papers/articles (Journal)
Changes in the structural features of osteoarthritis in a year of weight loss.
Jafarzadeh, SR; Clancy, M; Li, JS; Apovian, CM; Guermazi, A; Eckstein, F; Felson, DT;
Osteoarthritis Cartilage. 2018; 26(6): 775-782.
Full papers/articles (Journal)
Combining Heterogeneously Labeled Datasets For Training Segmentation Networks
Kemnitz, J; Baumgartner, CF; Wirth, W; Eckstein, F; Eder, SK; Konukoglu, E
LECT NOTES COMPUT SC. 2018; 11046: 276-284.
Full papers/articles (Journal)
The role of thigh muscle and adipose tissue in knee osteoarthritis progression in women: data from the Osteoarthritis Initiative.
Kemnitz, J; Wirth, W; Eckstein, F; Culvenor, AG;
Osteoarthritis Cartilage. 2018; 26(9): 1190-1195.
Full papers/articles (Journal)
Intentional Weight Loss in Overweight and Obese Patients With Knee Osteoarthritis: Is More Better?
Messier, SP; Resnik, AE; Beavers, DP; Mihalko, SL; Miller, GD; Nicklas, BJ; DeVita, P; Hunter, DJ; Lyles, MF; Eckstein, F; Guermazi, A; Loeser, RF;
Arthritis Care Res (Hoboken). 2018; 70(11): 1569-1575.
Full papers/articles (Journal)
From Early Radiographic Knee Osteoarthritis to Joint Arthroplasty: Determinants of Structural Progression and Symptoms.
Roemer, FW; Kwoh, CK; Fujii, T; Hannon, MJ; Boudreau, RM; Hunter, DJ; Eckstein, F; John, MR; Guermazi, A;
Arthritis Care Res (Hoboken). 2018; 70(12): 1778-1786.
Full papers/articles (Journal)
Sensitivity to change and association of three-dimensional meniscal measures with radiographic joint space width loss in rapid clinical progression of knee osteoarthritis.
Roth, M; Emmanuel, K; Wirth, W; Kwoh, CK; Hunter, DJ; Eckstein, F;
Eur Radiol. 2018; 28(5):1844-1853
Full papers/articles (Journal)
Relationship Between Knee Pain and Infrapatellar Fat Pad Morphology: A Within- and Between-Person Analysis From the Osteoarthritis Initiative.
Steidle-Kloc, E; Culvenor, AG; Dörrenberg, J; Wirth, W; Ruhdorfer, A; Eckstein, F;
Arthritis Care Res (Hoboken). 2018; 70(4):550-557
Full papers/articles (Journal)
Responsiveness of Infrapatellar Fat Pad Volume Change to Body Weight Loss or Gain: Data from the Osteoarthritis Initiative.
Steidle-Kloc, E; Dannhauer, T; Wirth, W; Eckstein, F;
Cells Tissues Organs. 2018; 205(1): 53-62.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
KNEE EXTENSOR MUSCLE WEAKNESS AND RADIOGRAPHIC KNEE OSTEOARTHRITIS PROGRESSION
Dell'isola, A; Wirth, W; Steultjens, M; Eckstein, F; Culvenor, A
CLIN EXP RHEUMATOL. 2018; 36(1): S24-S24.
Abstracts (Journal)
TRAJECTORIES OF FEMOROTIBIAL CARTILAGE THICKNESS AMONG PERSONS WITH OR AT RISK OF KNEE OSTEOARTHRITIS: DEVELOPMENT OF A PREDICTION MODEL TO IDENTIFY PROGRESSORS
Deveza, L; Downie, A; Eckstein, F; Spil, WEV; Hunter, D
INTERN MED J. 2018; 48: 10-10.
Abstracts (Journal)
EFFICACY AND SAFETY OF INTRA-ARTICULAR SPRIFERMIN IN SYMPTOMATIC RADIOGRAPHIC KNEE OSTEOARTHRITIS: PRE-SPECIFIED ANALYSIS OF 3-YEAR DATA FROM A 5-YEAR RANDOMISED, PLACEBO-CONTROLLED, PHASE II STUDY
Hochberg, M; Guermazi, A; Guehring, H; Aydemir, A; Wax, S; Fleuranceau-Morel, P; Bihlet, AR; Byrjalsen, I; Andersen, JR; Eckstein, F
ANN RHEUM DIS. 2018; 77: 80-81.
Abstracts (Journal)
EFFICACY AND SAFETY OF INTRA-ARTICULAR SPRIFERMIN IN SYMPTOMATIC RADIOGRAPHIC KNEE OSTEOARTHRITIS: PRE-SPECIFIED ANALYSIS OF 3-YEAR DATA FROM A 5-YEAR RANDOMIZED, PLACEBO-CONTROLLED, PHASE II STUDY
Hochberg, M; Guermazi, A; Guehring, H; Aydemir, A; Wax, S; Fleuranceau-Morel, P; Bihlet, AR; Byrjalsen, I; Andersen, JR; Eckstein, F
OSTEOARTHR CARTILAGE. 2018; 26: S26-S27.
Abstracts (Journal)
VALIDATION OF A 3D THIGH MUSCLE AND ADIPOSE TISSUE SEGMENTATION METHOD USING STATISTICAL SHAPE MODELS
Kemnitz, J; Eckstein, F; Culvenor, AG; Ruhdorfer, A; Dannhauer, T; Ring-Dimitriou, S; Sanger, AM; Wirth, W
OSTEOARTHR CARTILAGE. 2018; 26: S457-S458.
Abstracts (Journal)
THIGH MUSCLE AND ADIPOSE TISSUE CHANGES DURING SYMPTOMATIC AND RADIOGRAPHIC KNEE OSTEOARTHRITIS PROGRESSION - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Kemnitz, J; Wirth, W; Eckstein, F; Culvenor, AG
OSTEOARTHR CARTILAGE. 2018; 26: S406-S406.
Abstracts (Journal)
INCREASE IN PATELLOFEMORAL LOADING IS NOT ASSOCIATED WITH WORSENING SYMPTOMS OR STRUCTURE: SECONDARY ANALYSIS FROM THE IDEA TRIAL
Kumar, D; LaValley, MP; Beavers, DP; Guermazi, A; Eckstein, F; Hunter, DJ; Messier, SP
OSTEOARTHR CARTILAGE. 2018; 26: S18-S19.
Abstracts (Journal)
Predictive Probabilities Are Superior in Communicating the Clinical Relevance of Cartilage Thickness As an Imaging Biomarker of Knee Osteoarthritis Progression
Kwoh, CK; Ashbeck, EL; Bedrick, EJ; Eckstein, F
ARTHRITIS RHEUMATOL. 2018; 70:
Abstracts (Journal)
DOES RADIOGRAPHIC STATUS OF THE CONTRALATERAL KNEE IMPACT CARTILAGE THICKNESS CHANGE IN RADIOGRAPHICALLY NORMAL KNEES - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Mascheck, S; Wirth, W; Duda, GN; Sharma, L; Eckstein, F
OSTEOARTHR CARTILAGE. 2018; 26: S435-S436.
Abstracts (Journal)
Association of Adiposity Measures in Childhood and Adulthood with Knee Cartilage Thickness, Volume and Bone Area in Young Adults
Meng, T; Venn, A; Eckstein, F; Wirth, W; Cicuttini, F; March, L; Dwyer, T; Cross, M; Laslett, L; Jones, G; Ding, CH; Antony, BSE
ARTHRITIS RHEUMATOL. 2018; 70:
Abstracts (Journal)
ASSOCIATION OF CHILDHOOD AND ADULTHOOD ADIPOSITY MEASURES WITH KNEE CARTILAGE THICKNESS, CARTILAGE VOLUME AND BONE AREA IN YOUNG ADULTS
Meng, T; Venn, A; Eckstein, F; Wirth, W; Cicuttini, F; March, L; Dwyer, T; Cross, M; Laslett, LL; Jones, G; Ding, C; Antony, B
ANN RHEUM DIS. 2018; 77: 1144-1144.
Abstracts (Journal)
DECREASED MEDIAL COMPARTMENT LOADING AND INCREASED MEDIAL FEMOROTIBIAL ARTICULAR CARTILAGE THICKNESS 12 MONTHS AFTER LIMB REALIGNMENT SURGERY
Moyer, R; Birmingham, T; Lorbergs, A; Eckstein, F; Wirth, W; Giffin, JR
OSTEOARTHR CARTILAGE. 2018; 26: S279-S280.
Abstracts (Journal)
3D MENISCAL POSITION PREDICTS KNEE REPLACEMENT IN FAST PROGRESSING KNEE OSTEOARTHRITIS
Roth, M; Emmanuel, K; Wirth, W; Kwoh, C; Hunter, DJ; Hannon, MJ; Eckstein, F
OSTEOARTHR CARTILAGE. 2018; 26: S414-S415.
Abstracts (Journal)
CHANGES IN THIGH MUSCLE STRENGTH PRIOR TO AND CONCURRENT WITH INCIDENT KNEE PAIN - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Ruhdorfer, AS; Wirth, W; Culvenor, A; Eckstein, F
OSTEOARTHR CARTILAGE. 2018; 26: S411-S412.
Abstracts (Journal)
2017
Journal Articles
MRI findings of knee abnormalities in adolescent and adult volleyball players.
Boeth, H; MacMahon, A; Eckstein, F; Diederichs, G; Schlausch, A; Wirth, W; Duda, GN;
J Exp Orthop. 2017; 4(1): 6
Full papers/articles (Journal)
Choice of knee cartilage thickness change metric for different treatment goals in efficacy studies.
Buck, RJ; Le Graverand, MH; Wirth, W; Eckstein, F;
Semin Arthritis Rheum. 2017; 47(3):315-322
Full papers/articles (Journal)
Variance in infra-patellar fat pad volume: Does the body mass index matter?-Data from osteoarthritis initiative participants without symptoms or signs of knee disease.
Burda, B; Steidle-Kloc, E; Dannhauer, T; Wirth, W; Ruhdorfer, A; Eckstein, F;
Ann Anat. 2017; 213: 19-24.
Full papers/articles (Journal)
Thigh Muscle Specific-Strength and the Risk of Incident Knee Osteoarthritis: The Influence of Sex and Greater Body Mass Index.
Culvenor, AG; Felson, DT; Niu, J; Wirth, W; Sattler, M; Dannhauer, T; Eckstein, F;
Arthritis Care Res (Hoboken). 2017; 69(8): 1266-1270.
Full papers/articles (Journal)
Knee Extensor Strength and Risk of Structural, Symptomatic, and Functional Decline in Knee Osteoarthritis: A Systematic Review and Meta-Analysis.
Culvenor, AG; Ruhdorfer, A; Juhl, C; Eckstein, F; Øiestad, BE;
Arthritis Care Res (Hoboken). 2017; 69(5): 649-658.
Full papers/articles (Journal)
Longitudinal change in patellofemoral cartilage thickness, cartilage T2 relaxation times, and subchondral bone plate area in adolescent vs mature athletes.
Culvenor, AG; Wirth, W; Maschek, S; Boeth, H; Diederichs, G; Duda, G; Eckstein, F;
Eur J Radiol. 2017; 92:24-29
Full papers/articles (Journal)
Location-independent analysis of structural progression of osteoarthritis-Taking it all apart, and putting the puzzle back together makes the difference.
Eckstein, F; Buck, R; Wirth, W;
Semin Arthritis Rheum. 2017; 46(4): 404-410.
Reviews
Characterization of synthetic foam structures used to manufacture artificial vertebral trabecular bone.
Fürst, D; Senck, S; Hollensteiner, M; Esterer, B; Augat, P; Eckstein, F; Schrempf, A;
Mater Sci Eng C Mater Biol Appl. 2017; 76: 1103-1111.
Full papers/articles (Journal)
Validation of an active shape model-based semi-automated segmentation algorithm for the analysis of thigh muscle and adipose tissue cross-sectional areas.
Kemnitz, J; Eckstein, F; Culvenor, AG; Ruhdorfer, A; Dannhauer, T; Ring-Dimitriou, S; Sänger, AM; Wirth, W;
MAGMA. 2017; 30(5):489-503
Full papers/articles (Journal)
Longitudinal change in thigh muscle strength prior to and concurrent with symptomatic and radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative.
Kemnitz, J; Wirth, W; Eckstein, F; Ruhdorfer, A; Culvenor, AG;
Osteoarthritis Cartilage. 2017; 25(10): 1633-1640.
Full papers/articles (Journal)
Longitudinal Changes in Magnetic Resonance Imaging-Based Measures of Femorotibial Cartilage Thickness as a Function of Alignment and Obesity: Data From the Osteoarthritis Initiative.
Moyer, R; Wirth, W; Eckstein, F;
Arthritis Care Res (Hoboken). 2017; 69(7):959-965
Full papers/articles (Journal)
Impact of Diet and/or Exercise Intervention on Infrapatellar Fat Pad Morphology: Secondary Analysis from the Intensive Diet and Exercise for Arthritis (IDEA) Trial.
Pogacnik Murillo, AL; Eckstein, F; Wirth, W; Beavers, D; Loeser, RF; Nicklas, BJ; Mihalko, SL; Miller, GD; Hunter, DJ; Messier, SP;
Cells Tissues Organs. 2017; 203(4): 258-266.
Full papers/articles (Journal)
Partial meniscectomy is associated with increased risk of incident radiographic osteoarthritis and worsening cartilage damage in the following year.
Roemer, FW; Kwoh, CK; Hannon, MJ; Hunter, DJ; Eckstein, F; Grago, J; Boudreau, RM; Englund, M; Guermazi, A;
Eur Radiol. 2017; 27(1):404-413
Full papers/articles (Journal)
The contribution of 3D quantitative meniscal and cartilage measures to variation in normal radiographic joint space width-Data from the Osteoarthritis Initiative healthy reference cohort.
Roth, M; Wirth, W; Emmanuel, K; Culvenor, AG; Eckstein, F;
Eur J Radiol. 2017; 87: 90-98.
Full papers/articles (Journal)
Between-group differences in infra-patellar fat pad size and signal in symptomatic and radiographic progression of knee osteoarthritis vs non-progressive controls and healthy knees - data from the FNIH Biomarkers Consortium Study and the Osteoarthritis Initiative.
Ruhdorfer, A; Haniel, F; Petersohn, T; Dörrenberg, J; Wirth, W; Dannhauer, T; Hunter, DJ; Eckstein, F;
Osteoarthritis Cartilage. 2017; 25(7): 1114-1121.
Full papers/articles (Journal)
Association of knee pain with a reduction in thigh muscle strength - a cross-sectional analysis including 4553 osteoarthritis initiative participants.
Ruhdorfer, A; Wirth, W; Eckstein, F;
Osteoarthritis Cartilage. 2017; 25(5): 658-666.
Full papers/articles (Journal)
Five-Year Follow-up of Knee Joint Distraction: Clinical Benefit and Cartilaginous Tissue Repair in an Open Uncontrolled Prospective Study.
van der Woude, JAD; Wiegant, K; van Roermund, PM; Intema, F; Custers, RJH; Eckstein, F; van Laar, JM; Mastbergen, SC; Lafeber, FPJG;
CARTILAGE. 2017; 8(3): 263-271.
Full papers/articles (Journal)
Predictive and concurrent validity of cartilage thickness change as a marker of knee osteoarthritis progression: data from the Osteoarthritis Initiative.
Wirth, W; Hunter, DJ; Nevitt, MC; Sharma, L; Kwoh, CK; Ladel, C; Eckstein, F;
Osteoarthritis Cartilage. 2017; 25(12): 2063-2071.
Full papers/articles (Journal)
Subregional laminar cartilage MR spin-spin relaxation times (T2) in osteoarthritic knees with and without medial femorotibial cartilage loss - data from the Osteoarthritis Initiative (OAI).
Wirth, W; Maschek, S; Beringer, P; Eckstein, F;
Osteoarthritis Cartilage. 2017; 25(8): 1313-1323.
Full papers/articles (Journal)
Sex- and age-dependence of region- and layer-specific knee cartilage composition (spin-spin-relaxation time) in healthy reference subjects.
Wirth, W; Maschek, S; Eckstein, F;
Ann Anat. 2017; 210: 1-8.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
QUANTITATIVE CARTILAGE THICKNESS CHANGE PRECEDING SURGICAL AND VIRTUAL KNEE REPLACEMENT STATUS - COMPARATIVE ANALYSIS USING DATA FROM THE OAI
Eckstein, F; Hannon, MJ; Fujii, T; Boudreau, RM; Wirth, W; Maschek, S; Guermazi, A; Roemer, FW; Nevitt, M; Ladel, C; Sharma, L; Hunter, DJ; Kwoh, CK
OSTEOARTHR CARTILAGE. 2017; 25: S248-S249.
Abstracts (Journal)
CROSS-SECTIONAL DIFFERENCES AND LONGITUDINAL CHANGE IN THIGH MUSCLE STRENGTH PRIOR TO AND CONCURRENT WITH SYMPTOMATIC AND RADIOGRAPHIC KNEE OSTEOARTHRITIS PROGRESSION: DATA FROM THE OSTEOARTHRITIS INITIATIVE
Kemnitz, J; Wirth, W; Eckstein, F; Ruhdorfer, A; Culvenor, A
OSTEOARTHR CARTILAGE. 2017; 25: S188-S189.
Abstracts (Journal)
INCIDENT FREQUENT KNEE PAIN IS ASSOCIATED WITH INCIDENT AND INCREASED SEVERITY OF MRI-DETECTED STRUCTURAL PATHOLOGY IN KNEE OSTEOARTHRITIS
Kwoh, C; Hannon, MJ; Roemer, FW; Guermazi, A; Ashbeck, EL; Hunter, DJ; Eckstein, F; Boudreau, R
OSTEOARTHR CARTILAGE. 2017; 25: S245-S245.
Abstracts (Journal)
SENSITIVITY TO CHANGE OF 3D MENISCAL MEASURES IN RAPIDLY PROGRESSING KNEE OSTEOARTHRITIS AND ASSOCIATION WITH RADIOGRAPHIC JOINT SPACE WIDTH LOSS
Roth, M; Emmanuel, K; Wirth, W; Kwoh, C; Hunter, D; Eckstein, F
OSTEOARTHR CARTILAGE. 2017; 25: S238-S239.
Abstracts (Journal)
LONGITUDINAL CHANGE IN INFRAPATELLAR FAT PAD VOLUME AND MRI SIGNAL PRIOR TO TOTAL KNEE REPLACEMENT - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Ruhdorfer, AS; Wirth, W; Dorrenberg, J; Kwoh, CK; Hunter, DJ; Eckstein, F
OSTEOARTHR CARTILAGE. 2017; 25: S74-S75.
Abstracts (Journal)
LOCATION-INDPENDENT CROSS-SECTIONAL DIFFERENCES IN LAMINAR CARTILAGE T2 TIMES BETWEEN HEALTHY KNEES AND KNEES AT DIFFERENT STAGES OF RADIOGRAPHIC OSTEOARTHRITIS - DATA FROM THE OSTEOARTHRITIS INITIATIVE (OAI)
Wirth, W; Maschek, S; Eckstein, F
OSTEOARTHR CARTILAGE. 2017; 25: S246-S247.
Abstracts (Journal)
BASELINE VALUES AND CHANGE IN SUPERFICIAL AND DEEP LAYER CARTILAGE T2 TIMES IN EXTERNAL FEMORAL SUBREGIONS DO NOT DIFFER BETWEEN KNEES WITH AND WITHOUT OSTEOPHYTES - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Wirth, W; Maschek, S; Roemer, F; Eckstein, F
OSTEOARTHR CARTILAGE. 2017; 25: S248-S248.
Abstracts (Journal)
2016
Journal Articles
Thigh Muscle Strength Predicts Knee Replacement Risk Independent of Radiographic Disease and Pain in Women: Data From the Osteoarthritis Initiative.
Culvenor, A; Wirth, W; Ruhdorfer, A; Eckstein, F;
Arthritis Rheumatol. 2016; 68(5): 1145-1155.
Full papers/articles (Journal)
Longitudinal bone, muscle and adipose tissue changes in physically active subjects - sex differences during adolescence and maturity.
Culvenor, AG; Boeth, H; Diederichs, G; Wirth, W; Duda, G; Eckstein, F;
J Musculoskelet Neuronal Interact. 2016; 16(3): 237-246.
Full papers/articles (Journal)
Predictive Capacity of Thigh Muscle Strength in Symptomatic and/or Radiographic Knee Osteoarthritis Progression: Data from the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium.
Culvenor, AG; Wirth, W; Roth, M; Hunter, DJ; Eckstein, F;
Am J Phys Med Rehabil. 2016; 95(12):931-938
Full papers/articles (Journal)
Primary or secondary effect of quadriceps exercises on subsequent need for knee replacement? Reply.
Culvenor, AG; Wirth, W; Ruhdorfer, A; Eckstein, F;
Arthritis Rheumatol. 2016; 68(11): 2829-2830.
Author reply
Comparison of radiographic joint space width and magnetic resonance imaging for prediction of knee replacement: A longitudinal case-control study from the Osteoarthritis Initiative.
Eckstein, F; Boudreau, R; Wang, Z; Hannon, MJ; Duryea, J; Wirth, W; Cotofana, S; Guermazi, A; Roemer, F; Nevitt, M; John, MR; Ladel, C; Sharma, L; Hunter, DJ; Kwoh, CK;
Eur Radiol. 2016; 26(6):1942-1951
Full papers/articles (Journal)
A 20 years of progress and future of quantitative magnetic resonance imaging (qMRI) of cartilage and articular tissues-personal perspective.
Eckstein, F; Peterfy, C;
Semin Arthritis Rheum. 2016; 45(6):639-647
Full papers/articles (Journal)
Quantitative measures of meniscus extrusion predict incident radiographic knee osteoarthritis - data from the Osteoarthritis Initiative.
Emmanuel, K; Quinn, E; Niu, J; Guermazi, A; Roemer, F; Wirth, W; Eckstein, F; Felson, D;
Osteoarthritis Cartilage. 2016; 24(2): 262-269.
Full papers/articles (Journal)
Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment: data from the Osteoarthritis Initiative.
Moyer, R; Wirth, W; Duryea, J; Eckstein, F;
Osteoarthritis Cartilage. 2016; 24(2):254-261
Full papers/articles (Journal)
Structural effects of sprifermin in knee osteoarthritis: a post-hoc analysis on cartilage and non-cartilaginous tissue alterations in a randomized controlled trial.
Roemer, FW; Aydemir, A; Lohmander, S; Crema, MD; Marra, MD; Muurahainen, N; Felson, DT; Eckstein, F; Guermazi, A
BMC MUSCULOSKEL DIS. 2016; 17: 267
Full papers/articles (Journal)
Longitudinal Change in Thigh Muscle Strength Prior to and Concurrent With Minimum Clinically Important Worsening or Improvement in Knee Function: Data From the Osteoarthritis Initiative.
Ruhdorfer, A; Wirth, W; Eckstein, F;
Arthritis Rheumatol. 2016; 68(4): 826-836.
Full papers/articles (Journal)
Intra- and inter-observer reliability of quantitative analysis of the infra-patellar fat pad and comparison between fat- and non-fat-suppressed imaging--Data from the osteoarthritis initiative.
Steidle-Kloc, E; Wirth, W; Ruhdorfer, A; Dannhauer, T; Eckstein, F;
Ann Anat. 2016; 204:29-35
Full papers/articles (Journal)
Six weeks of continuous joint distraction appears sufficient for clinical benefit and cartilaginous tissue repair in the treatment of knee osteoarthritis.
van der Woude, JA; van Heerwaarden, RJ; Spruijt, S; Eckstein, F; Maschek, S; van Roermund, PM; Custers, RJ; van Spil, WE; Mastbergen, SC; Lafeber, FP;
Knee. 2016; 23(5): 785-791.
Full papers/articles (Journal)
Layer-specific femorotibial cartilage T2 relaxation time in knees with and without early knee osteoarthritis: Data from the Osteoarthritis Initiative (OAI)
Wirth, W; Maschek, S; Roemer, FW; Eckstein, F
SCI REP-UK. 2016; 6: 34202
Full papers/articles (Journal)
Relationship of Buckling and Knee Injury to Pain Exacerbation in Knee Osteoarthritis: A Web-Based Case-Crossover Study.
Zobel, I; Erfani, T; Bennell, KL; Makovey, J; Metcalf, B; Chen, JS; March, L; Zhang, Y; Eckstein, F; Hunter, DJ;
Interact J Med Res. 2016; 5(2): e17
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
PREDICTIVE CAPACITY OF THIGH MUSCLE STRENGTH IN SYMPTOMATIC AND/OR RADIOGRAPHIC KNEE OSTEOARTHRITIS PROGRESSION-DATA FROM THE FNIH OA BIOMARKERS CONSORTIUM
Culvenor, A; Wirth, W; Roth, M; Hunter, D; Eckstein, F
OSTEOARTHR CARTILAGE. 2016; 24: S417-S418.
Abstracts (Journal)
DOES MUSCLE STRENGTH PREDICT RISK OF KNEE REPLACEMENT INDEPENDENT OF RADIOGRAPHIC DISEASE STATUS AND PAIN? - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Culvenor, A; Wirth, W; Ruhdorfer, A; Eckstein, F
OSTEOARTHR CARTILAGE. 2016; 24: S422-S423.
Abstracts (Journal)
CARTILAGE THICKNESS LOSS AND CLINICAL WORSENING ARE ASSOCIATED IN OSTEOARTHRITIC KNEES REACHING VIRTUAL REPLACEMENT STATUS - A NESTED CASE CONTROL STUDY FROM THE OSTEOARTHRITIS INITIATIVE
Eckstein, F; Boudreau, RM; Fujii, T; Hannon, MJ; Wirth, W; Maschek, S; Guermazi, A; Roemer, F; Nevitt, M; Sharma, L; Hunter, D; Kwoh, KC
OSTEOARTHR CARTILAGE. 2016; 24: S245-S246.
Abstracts (Journal)
TWO-YEAR CHANGE IN CARTILAGE THICKNESS ON QUANTITATIVE MAGNETIC RESONANCE IMAGING (QMRI) AND JOINT SPACE WIDTH (JSW) ON X-RAY DEMONSTRATE SIMILAR PREDICTIVE PERFORMANCE FOR KNEE REPLACEMENT IN OA SUBJECTS ELIGIBLE FOR CLINICAL TRIALS
Kwoh, K; Muurahainen, N; Aydemir, A; Ashbeck, E; Hannon, M; Eckstein, F; Hochberg, M
OSTEOARTHR CARTILAGE. 2016; 24: S260-S261.
Abstracts (Journal)
IMPACT OF MEDIUM TERM BED REST ON SERUM LEVELS OF CARTILAGE OLIGOMERIC MATRIX PROTEIN
Liphardt, AM; Bruggemann, GP; Hamann, N; Zaucke, F; Eckstein, F; Bloch, W; Mundermann, A; Koo, S; Mester, J; Niehoff, A
OSTEOARTHR CARTILAGE. 2016; 24: S151-S152.
Abstracts (Journal)
DOES LONG-TERM INTENSIVE DIET AND EXERCISE REDUCE THE BIOMECHANICAL BURDEN IN OVERWEIGHT AND OBESE ADULTS WITH KNEE OSTEOARTHRITIS? THE INTENSIVE DIET AND EXERCISE FOR ARTHRITIS (IDEA) TRIAL
Messier, SP; Beavers, D; Mihalko, SL; Miller, GD; Nicklas, BJ; Lyles, M; Hunter, DJ; Carr, JJ; Eckstein, F; Guermazi, A; Loeser, RF; DeVita, P
OSTEOARTHR CARTILAGE. 2016; 24: S47-S48.
Abstracts (Journal)
LONGITUDINAL CHANGE IN FEMOROTIBIAL CARTILAGE THICKNESS ARE CONTINGENT ON MALALIGNMENT, BUT NOT ON ITS SEVERITY, DIRECTION, OR THE BODY MASS INDEX
Moyer, R; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2016; 24: S265-S266.
Abstracts (Journal)
AT WHICH LOCATION IS THE INFRAPATELLAR FAT PAD MOST SENSITIVE TO REDUCTION BY DIET AND EXERCISE INTERVENTION - DATA FROM THE INTENSIVE DIET AND EXERCISE FOR ARTHRITIS (IDEA) TRIAL
Murillo, ALP; Wirth, W; Beavers, DP; Dannhauer, T; Loeser, RF; Nicklas, BJ; Mihalko, SL; Miller, GD; Hunter, DJ; Eckstein, F; Messier, SP
OSTEOARTHR CARTILAGE. 2016; 24: S242-S242.
Abstracts (Journal)
LONG-DURATION SPACE FLIGHT AND CARTILAGE ADAPTATION: FIRST RESULTS ON CHANGES IN TISSUE METABOLISM
Niehoff, A; Bruggemann, GP; Zaucke, F; Eckstein, F; Bloch, W; Mundermann, A; Koo, S; Mester, J; Liphardt, AM
OSTEOARTHR CARTILAGE. 2016; 24: S144-S145.
Abstracts (Journal)
WHY DO KNEES WITH EARLY OSTEOARTHRITIS UNDERGO KNEE ARTHROPLASTY IN A SHORT PERIOD OF TIME? - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Roemer, FW; Kwoh, C; Fujii, T; Hannon, M; Boudreau, R; Hunter, DJ; Eckstein, F; Guermazi, A
OSTEOARTHR CARTILAGE. 2016; 24: S268-S268.
Abstracts (Journal)
THE CONTRIBUTION OF 3D MENISCUS AND CARTILAGE MEASURES TO NORMAL RADIOGRAPHIC JOINT SPACE WIDTH - DATA FROM THE OSTEOARTHRITIS INITIATIVE HEALTHY REFERENCE COHORT
Roth, M; Wirth, W; Emmanuel, K; Culvenor, A; Eckstein, F
OSTEOARTHR CARTILAGE. 2016; 24: S244-S245.
Abstracts (Journal)
DOES (CHANGE IN) INFRA-PATELLAR FAT PAD VOLUME AND MRI SIGNAL PREDICT SYMPTOMATIC AND STRUCTURAL PROGRESSION OF KNEE OSTEOARTHRITIS? - DATA FROM THE FNIH BIOMARKER CONSORTIUM COHORT
Ruhdorfer, AS; Hunter, DJ; Wirth, W; Dannhauer, T; Dorrenberg, J; Haniel, F; Petersohn, T; Eckstein, F
OSTEOARTHR CARTILAGE. 2016; 24: S289-S290.
Abstracts (Journal)
INTER- *** INTRA-OBSERVER RELIABILITY OF THIGH MUSCLE AND ADIPOSE TISSUE CROSS-SECTIONAL AREA ANALYSIS FROM MR IMAGES
Ruhdorfer, AS; Steidle, E; Diepold, J; Murillo, ALP; Dannhauer, T; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2016; 24: S415-S415.
Abstracts (Journal)
SIX WEEKS OF KNEE JOINT DISTRACTION: SUFFICIENT FOR CARTILAGE TISSUE REPAIR
van Woude, JT; van Heerwaarden, RJ; Spruijt, S; Eckstein, F; Maschek, S; van Roermund, PM; Custers, RJ; Mastbergen, SC; Lafeber, FP
OSTEOARTHR CARTILAGE. 2016; 24: S513-S513.
Abstracts (Journal)
PREDICTIVE VS CONCURRENT VALIDITY OF CARTILAGE THICKNESS CHANGE AS A MARKER OF PROGRESSION OF KNEE OSTEOARTHRITIS - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Wirth, W; Hunter, DJ; Nevitt, MC; Kwoh, CK; Sharma, L; Guermazi, A; Roemer, F; Eckstein, F
OSTEOARTHR CARTILAGE. 2016; 24: S241-S241.
Abstracts (Journal)
CLINICAL VALIDATION OF A REGULATORY COMPLIANT SOFTWARE FOR QUANTITATIVE ANALYSIS OF ARTICULAR CARTILAGE MORPHOLOGY
Wirth, W; Maschek, S; Haefner, P; Boeth, H; Duda, G; Eckstein, F
OSTEOARTHR CARTILAGE. 2016; 24: S247-S247.
Abstracts (Journal)
2015
Journal Articles
Longitudinal change in quantitative meniscus measurements in knee osteoarthritis-data from the Osteoarthritis Initiative.
Bloecker, K; Wirth, W; Guermazi, A; Hitzl, W; Hunter, DJ; Eckstein, F;
Eur Radiol. 2015; 25(10): 2960-2968.
Full papers/articles (Journal)
Relationship Between Medial Meniscal Extrusion and Cartilage Loss in Specific Femorotibial Subregions: Data From the Osteoarthritis Initiative.
Bloecker, K; Wirth, W; Guermazi, A; Hunter, DJ; Resch, H; Hochreiter, J; Eckstein, F;
Arthritis Care Res (Hoboken). 2015; 67(11): 1545-1552.
Full papers/articles (Journal)
External knee adduction and flexion moments during gait and medial tibiofemoral disease progression in knee osteoarthritis.
Chang, AH; Moisio, KC; Chmiel, JS; Eckstein, F; Guermazi, A; Prasad, PV; Zhang, Y; Almagor, O; Belisle, L; Hayes, K; Sharma, L;
Osteoarthritis Cartilage. 2015; 23(7):1099-1106
Full papers/articles (Journal)
Contralateral knee effect on self-reported knee-specific function and global functional assessment: data from the osteoarthritis initiative.
Cotofana, S; Wirth, W; Pena Rossi, C; Eckstein, F; Günther, OH;
Arthritis Care Res (Hoboken). 2015; 67(3): 374-381.
Full papers/articles (Journal)
Quantitative relationship of thigh adipose tissue with pain, radiographic status, and progression of knee osteoarthritis: longitudinal findings from the osteoarthritis initiative.
Dannhauer, T; Ruhdorfer, A; Wirth, W; Eckstein, F;
Invest Radiol. 2015; 50(4):268-274
Full papers/articles (Journal)
Sex-differences of the healthy infra-patellar (Hoffa) fat pad in relation to intermuscular and subcutaneous fat content - Data from the Osteoarthritis Initiative.
Diepold, J; Ruhdorfer, A; Dannhauer, T; Wirth, W; Steidle, E; Eckstein, F;
Ann Anat. 2015; 200: 30-36.
Full papers/articles (Journal)
Brief Report: Cartilage Thickness Change as an Imaging Biomarker of Knee Osteoarthritis Progression: Data From the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium.
Eckstein, F; Collins, JE; Nevitt, MC; Lynch, JA; Kraus, V; Katz, JN; Losina, E; Wirth, W; Guermazi, A; Roemer, FW; Hunter, DJ;
Arthritis Rheumatol. 2015; 67(12): 3184-3189.
Full papers/articles (Journal)
Plain radiography or magnetic resonance imaging (MRI): Which is better in assessing outcome in clinical trials of disease-modifying osteoarthritis drugs? Summary of a debate held at the World Congress of Osteoarthritis 2014.
Eckstein, F; Le Graverand, MH;
Semin Arthritis Rheum. 2015; 45(3):251-256
Reviews
Brief Report: Intraarticular Sprifermin Not Only Increases Cartilage Thickness, but Also Reduces Cartilage Loss: Location-Independent Post Hoc Analysis Using Magnetic Resonance Imaging.
Eckstein, F; Wirth, W; Guermazi, A; Maschek, S; Aydemir, A;
Arthritis Rheumatol. 2015; 67(11): 2916-2922.
Full papers/articles (Journal)
Five-year followup of knee joint cartilage thickness changes after acute rupture of the anterior cruciate ligament.
Eckstein, F; Wirth, W; Lohmander, LS; Hudelmaier, MI; Frobell, RB;
Arthritis Rheumatol. 2015; 67(1):152-161
Full papers/articles (Journal)
OARSI Clinical Trials Recommendations: Hip imaging in clinical trials in osteoarthritis.
Gold, GE; Cicuttini, F; Crema, MD; Eckstein, F; Guermazi, A; Kijowski, R; Link, TM; Maheu, E; Martel-Pelletier, J; Miller, CG; Pelletier, JP; Peterfy, CG; Potter, HG; Roemer, FW; Hunter, DJ
OSTEOARTHR CARTILAGE. 2015; 23(5): 716-731.
Reviews
Baseline radiographic osteoarthritis and semi-quantitatively assessed meniscal damage and extrusion and cartilage damage on MRI is related to quantitatively defined cartilage thickness loss in knee osteoarthritis: the Multicenter Osteoarthritis Study.
Guermazi, A; Eckstein, F; Hayashi, D; Roemer, FW; Wirth, W; Yang, T; Niu, J; Sharma, L; Nevitt, MC; Lewis, CE; Torner, J; Felson, DT;
Osteoarthritis Cartilage. 2015; 23(12): 2191-2198.
Full papers/articles (Journal)
7th International Workshop on Osteoarthritis Imaging report: "imaging in OA - now is the time to move ahead".
Guermazi, A; Eckstein, F; Hunter, D; Roemer, F;
Osteoarthritis Cartilage. 2015; 23(6): 888-896.
Full papers/articles (Journal)
Train High Eat Low for Osteoarthritis study (THE LO study): protocol for a randomized controlled trial.
Guerrero, Y; Soomro, N; Wilson, G; Dam, Y; Meiklejohn, J; Simpson, K; Smith, R; Brand-Miller, J; Simic, M; O"Connor, H; Mavros, Y; Foroughi, N; Poon, T; Bradshaw, K; March, L; Vanwanseele, B; Eckstein, F; Fransen, M; Bergamasco, J; Anandacoomarasamy, A; Singh, MF;
J Physiother. 2015; 61(4):217
Full papers/articles (Journal)
Greater Lateral Femorotibial Cartilage Loss in Osteoarthritis Initiative Participants With Incident Total Knee Arthroplasty: A Prospective Cohort Study.
Hitzl, W; Wirth, W; Maschek, S; Cotofana, S; Nevitt, M; John, MR; Ladel, C; Eckstein, F;
Arthritis Care Res (Hoboken). 2015; 67(10): 1481-1486.
Full papers/articles (Journal)
OARSI Clinical Trials Recommendations: Knee imaging in clinical trials in osteoarthritis (vol 23, pg 698, 2015)
Hunter, DJ; Altman, RD; Cicuttini, F; Crema, MD; Duryea, J; Eckstein, F; Guermazi, A; Kijowski, R; Link, TM; Martel-Pelletier, J; Miller, CG; Mosher, TJ; Ochoa-Albiztegui, RE; Pelletier, JP; Peterfy, C; Raynauld, JP; Roemer, FW; Totterman, SM; Gold, GE
OSTEOARTHR CARTILAGE. 2015; 23(8): 1434-1435.
Corrections
OARSI Clinical Trials Recommendations: Knee imaging in clinical trials in osteoarthritis.
Hunter, DJ; Altman, RD; Cicuttini, F; Crema, MD; Duryea, J; Eckstein, F; Guermazi, A; Kijowski, R; Link, TM; Martel-Pelletier, J; Miller, CG; Mosher, TJ; Ochoa-Albiztegui, RE; Pelletier, JP; Peterfy, C; Raynauld, JP; Roemer, FW; Totterman, SM; Gold, GE
Osteoarthritis Cartilage. 2015; 23(5):698-715
Reviews
The Intensive Diet and Exercise for Arthritis (IDEA) trial: 18-month radiographic and MRI outcomes.
Hunter, DJ; Beavers, DP; Eckstein, F; Guermazi, A; Loeser, RF; Nicklas, BJ; Mihalko, SL; Miller, GD; Lyles, M; DeVita, P; Legault, C; Carr, JJ; Williamson, JD; Messier, SP
Osteoarthritis Cartilage. 2015; 23(7):1090-1098
Full papers/articles (Journal)
Sensitivity of different measures of frontal plane alignment to medial and lateral joint space narrowing: From the osteoarthritis initiative.
Moyer, R; Wirth, W; Eckstein, F;
Semin Arthritis Rheum. 2015; 45(3): 268-274.
Full papers/articles (Journal)
Sample Size Calculations for Detecting Disease-Modifying Osteoarthritis Drug Effects on Knee Replacement Incidence in Clinical Trials: Data From the Osteoarthritis Initiative.
Ried, JS; Flechsenhar, K; Bartnik, E; Crowther, D; Dietrich, A; Eckstein, F;
Arthritis Rheumatol. 2015; 67(12): 3174-3183.
Full papers/articles (Journal)
What Comes First? Multitissue Involvement Leading to Radiographic Osteoarthritis: Magnetic Resonance Imaging-Based Trajectory Analysis Over Four Years in the Osteoarthritis Initiative.
Roemer, FW; Kwoh, CK; Hannon, MJ; Hunter, DJ; Eckstein, F; Fujii, T; Boudreau, RM; Guermazi, A
ARTHRITIS RHEUMATOL. 2015; 67(8): 2085-2096.
Full papers/articles (Journal)
Can Structural Joint Damage Measured with MR Imaging Be Used to Predict Knee Replacement in the Following Year?
Roemer, FW; Kwoh, CK; Hannon, MJ; Hunter, DJ; Eckstein, F; Wang, Z; Boudreau, RM; John, MR; Nevitt, MC; Guermazi, A;
Radiology. 2015; 274(3):810-820
Full papers/articles (Journal)
Longitudinal (4 year) change of thigh muscle and adipose tissue distribution in chronically painful vs painless knees - data from the Osteoarthritis Initiative.
Ruhdorfer, A; Wirth, W; Dannhauer, T; Eckstein, F;
Osteoarthritis Cartilage. 2015; 23(8): 1348-1356.
Full papers/articles (Journal)
Relationship between isometric thigh muscle strength and minimum clinically important differences in knee function in osteoarthritis: data from the osteoarthritis initiative.
Ruhdorfer, A; Wirth, W; Eckstein, F;
Arthritis Care Res (Hoboken). 2015; 67(4): 509-518.
Full papers/articles (Journal)
Is Pain in One Knee Associated with Isometric Muscle Strength in the Contralateral Limb?: Data From the Osteoarthritis Initiative.
Steidle-Kloc, E; Wirth, W; Glass, NA; Ruhdorfer, A; Cotofana, S; Eckstein, F; Segal, NA;
Am J Phys Med Rehabil. 2015; 94(10): 792-803.
Full papers/articles (Journal)
OVERLOAD of joints and its role in osteoarthritis : Towards understanding and preventing progression of primary osteoarthritis.
Willie, BM; Pap, T; Perka, C; Schmidt, CO; Eckstein, F; Arampatzis, A; Hege, HC; Madry, H; Vortkamp, A; Duda, GN;
Z Rheumatol. 2015; 74(7): 618-621.
Notes
Conference papers, proceedings, abstracts
LONGTERM PROFESSIONAL ATHLETIC ACTIVITY RESULTS IN INCREASED STRUCTURAL KNEE JOINT SYNOVIAL TISSUE PATHOLOGY
Boeth, H; Eckstein, F; Diederichs, G; Schlausch, A; Wirth, W; Duda, GN
OSTEOARTHR CARTILAGE. 2015; 23: A238-A239.
Abstracts (Journal)
INFRA-PATELLAR FAT PAD MORPHOLOGY AND MRI SIGNAL DISTRIBUTION IN ADVANCED RADIOGRAPHIC KNEE OA - DATA FROM THE OAI
Eckstein, F; Diepold, J; Ruhdorfer, A; Dannhauer, T; Wirth, W; Guermazi, A
OSTEOARTHR CARTILAGE. 2015; 23: A219-A219.
Abstracts (Journal)
Incident Frequent Knee Pain Is Associated with Changes in Semi-Quantitative Imaging Biomarkers of Inflammation
Kwoh, CK; Hannon, MJ; Fujii, T; Roemer, FW; Guermazi, A; Hunter, D; Eckstein, F; Boudreau, RM
ARTHRITIS RHEUMATOL. 2015; 67:
Abstracts (Journal)
IMPACT OF DIET AND/OR EXERCISE INTERVENTION ON INFRA-PATELLAR FAT PAD MORPHOLOGY - DATA FROM THE INTENSIVE DIET AND EXERCISE FOR ARTHRITIS (IDEA) TRIAL
Murillo, ALP; Wirth, W; Beavers, D; Loeser, RF; Nicklas, BJ; Miller, GD; Hunter, D; Eckstein, F; Messier, SP
OSTEOARTHR CARTILAGE. 2015; 23: A389-A390.
Abstracts (Journal)
Structural Effects of Sprifermin in Knee Osteoarthritis: A Post-Hoc Analysis on Cartilage and Non-Cartilaginous Tissue Alterations
Roemer, F; Aydemir, A; Lohmander, S; Crema, M; Marra, MD; Muurahainen, N; Eckstein, F; Guermazi, A
ARTHRITIS RHEUMATOL. 2015; 67:
Abstracts (Journal)
PRESENCE OF MRI MARKERS OF INFLAMMATION ESPECIALLY IN OVERWEIGHT PERSONS INCREASES RISK OF INCIDENT OA: THE POMA STUDY
Roemer, FW; Guermazi, A; Hannon, M; Fujii, T; Boudreau, RM; Hunter, DJ; Eckstein, F; Kwoh, CK
OSTEOARTHR CARTILAGE. 2015; 23: A75-A75.
Abstracts (Journal)
INCIDENT MRI FEATURES DURING 4 YEARS PRIOR INCREASE RISK FOR RADIOGRAPHIC OSTEOARTHRITIS DEVELOPMENT
Roemer, FW; Guermazi, A; Hannon, MJ; Hunter, DJ; Fujii, T; Eckstein, F; Boudreau, RM; Kwoh, CK
OSTEOARTHR CARTILAGE. 2015; 23: A234-A234.
Abstracts (Journal)
LESION LOAD INCREASES RISK FOR OSTEOARTHRITIS DEVELOPMENT: A 4 YEAR LONGITUDINAL MRI-BASED MULTI-TISSUE ANALYSIS IN THE OSTEOARTHRITIS INITIATIVE
Roemer, FW; Kwoh, C; Hannon, MJ; Hunter, DJ; Eckstein, F; Fujii, T; Boudreau, RM; Guermazi, A
OSTEOARTHR CARTILAGE. 2015; 23: A232-A233.
Abstracts (Journal)
THIGH MUSCLE STRENGTH CHANGES CONCURRENTLY TO WORSENING AND IMPROVEMENT, BUT DOES NOT PREDICT SELF-ASSESSED WOMAC KNEE FUNCTION - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Ruhdorfer, A; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2015; 23: A350-A351.
Abstracts (Journal)
RESPONSIVENESS OF INFRA-PATELLAR FAT PAD (IPFP) VOLUME CHANGE WITH SEVERE BODY WEIGHT GAIN AND LOSS - DATA FROM THE OAI
Steidle-Kloc, E; Dannhauer, T; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2015; 23: A212-A213.
Abstracts (Journal)
KNEE PAIN IS NOT RELATED TO ALTERATIONS IN THE MORPHOLOGY OR MRI SIGNAL OF THE INFRA-PATELLAR FAT PAD (IPFP) - A WITHIN-PERSON AND BETWEEN-PERSON ANALYSIS USING DATA FROM THE OSTEOARTHRITIS INITIATIVE (OAI)
Steidle-Kloc, E; Dorrenberg, J; Wirth, W; Ruhdorfer, A; Eckstein, F
OSTEOARTHR CARTILAGE. 2015; 23: A59-A60.
Abstracts (Journal)
CHANGE IN CARTILAGE T2 RELAXATION TIME IN OSTEOARTHRITIC KNEES WITH AND WITHOUT STRUCTURAL PROGRESSION - PILOT DATA FROM THE OSTEOARTHRITIS INITIATIVE
Wirth, W; Maschek, S; Beringer, P; Eckstein, F
OSTEOARTHR CARTILAGE. 2015; 23: A210-A211.
Abstracts (Journal)
2014
Journal Articles
Prediction of bone strength by mu CT and MDCT-based finite-element-models: How much spatial resolution is needed?
Bauer, JS; Sidorenko, I; Mueller, D; Baum, T; Issever, AS; Eckstein, F; Rummeny, EJ; Link, TM; Raeth, CW
EUR J RADIOL. 2014; 83(1): E36-E42.
Full papers/articles (Journal)
Correlation of semiquantitative vs quantitative MRI meniscus measures in osteoarthritic knees: results from the Osteoarthritis Initiative.
Bloecker, K; Guermazi, A; Wirth, W; Kwoh, CK; Resch, H; Hunter, DJ; Eckstein, F;
Skeletal Radiol. 2014; 43(2): 227-232.
Full papers/articles (Journal)
Meniscus body position and its change over four years in asymptomatic adults: a cohort study using data from the Osteoarthritis Initiative (OAI)
Bruns, K; Svensson, F; Turkiewicz, A; Wirth, W; Guermazi, A; Eckstein, F; Englund, M
BMC MUSCULOSKEL DIS. 2014; 15(1): 32
Full papers/articles (Journal)
Is loss in femorotibial cartilage thickness related to severity of contra-lateral radiographic knee osteoarthritis? - Longitudinal data from the Osteoarthritis Initiative.
Cotofana, S; Benichou, O; Hitzl, W; Wirth, W; Eckstein, F;
Osteoarthritis Cartilage. 2014; 22(12):2059-2066
Full papers/articles (Journal)
Longitudinal (one-year) change in cartilage thickness in knees with early knee osteoarthritis: A within-person between-knee comparison.
Cotofana, S; Buck, R; Dreher, D; Wirth, W; Roemer, F; Duryea, J; Nevitt, M; Eckstein, F
Arthritis Care Res (Hoboken). 2014; 66(4):636-641
Full papers/articles (Journal)
Association of changes in delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) with changes in cartilage thickness in the medial tibiofemoral compartment of the knee: a 2 year follow-up study using 3.0 T MRI.
Crema, MD; Hunter, DJ; Burstein, D; Roemer, FW; Li, L; Eckstein, F; Krishnan, N; Hellio Le-Graverand, MP; Guermazi, A;
Ann Rheum Dis. 2014; 73(11):1935-1941
Full papers/articles (Journal)
Longitudinal sensitivity to change of MRI-based muscle cross-sectional area versus isometric strength analysis in osteoarthritic knees with and without structural progression: pilot data from the Osteoarthritis Initiative.
Dannhauer, T; Sattler, M; Wirth, W; Hunter, DJ; Kwoh, CK; Eckstein, F;
MAGMA. 2014; 27(4):339-347
Full papers/articles (Journal)
Quantitative versus semiquantitative MR imaging of cartilage in blood-induced arthritic ankles: preliminary findings.
Doria, AS; Zhang, NN; Lundin, B; Hilliard, P; Man, C; Weiss, R; Detzler, G; Blanchette, V; Moineddin, R; Eckstein, F; Sussman, MS
Pediatr Radiol. 2014; 44(5):576-586
Full papers/articles (Journal)
Longitudinal change in femorotibial cartilage thickness and subchondral bone plate area in male and female adolescent vs. mature athletes.
Eckstein, F; Boeth, H; Diederichs, G; Wirth, W; Hudelmaier, M; Cotofana, S; Hofmann-Amtenbrink, M; Duda, G;
Ann Anat. 2014; 196(2-3):150-157
Full papers/articles (Journal)
Trajectory of cartilage loss within 4 years of knee replacement--a nested case-control study from the osteoarthritis initiative.
Eckstein, F; Boudreau, RM; Wang, Z; Hannon, MJ; Wirth, W; Cotofana, S; Guermazi, A; Roemer, F; Nevitt, M; John, MR; Ladel, C; Sharma, L; Hunter, DJ; Kwoh, CK;
Osteoarthritis Cartilage. 2014; 22(10):1542-1549
Full papers/articles (Journal)
Imaging of cartilage and bone: promises and pitfalls in clinical trials of osteoarthritis.
Eckstein, F; Guermazi, A; Gold, G; Duryea, J; Hellio Le Graverand, MP; Wirth, W; Miller, CG;
Osteoarthritis Cartilage. 2014; 22(10):1516-1532
Reviews
Imaging in rheumatology in 2013: From images to data to theory.
Eckstein, F; Kwoh, CK;
Nat Rev Rheumatol. 2014; 10(2): 69-70.
Notes
Imaging research results from the Osteoarthritis Initiative (OAI): a review and lessons learned 10 years after start of enrolment.
Eckstein, F; Kwoh, CK; Link, TM;
Ann Rheum Dis. 2014; 73(7): 1289-1300.
Full papers/articles (Journal)
Monitoring the effects of dexamethasone treatment by MRI using in vivo iron oxide nanoparticle-labeled macrophages.
Gramoun, A; Crowe, LA; Maurizi, L; Wirth, W; Tobalem, F; Grosdemange, K; Coullerez, G; Eckstein, F; Koenders, MI; Van den Berg, WB; Hofmann, H; Vallée, JP;
Arthritis Res Ther. 2014; 16(3):R131
Full papers/articles (Journal)
Locally measured microstructural parameters are better associated with vertebral strength than whole bone density.
Hazrati Marangalou, J; Eckstein, F; Kuhn, V; Ito, K; Cataldi, M; Taddei, F; van Rietbergen, B;
Osteoporos Int. 2014; 25(4): 1285-1296.
Full papers/articles (Journal)
Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial.
Lohmander, LS; Hellot, S; Dreher, D; Krantz, EF; Kruger, DS; Guermazi, A; Eckstein, F;
Arthritis Rheumatol. 2014; 66(7): 1820-1831.
Full papers/articles (Journal)
Rates and sensitivity of knee cartilage thickness loss in specific central reading radiographic strata from the osteoarthritis initiative.
Maschek, S; Wirth, W; Ladel, C; Hellio Le Graverand, MP; Eckstein, F;
Osteoarthritis Cartilage. 2014; 22(10):1550-1553
Full papers/articles (Journal)
The role of imaging in osteoarthritis.
Roemer, FW; Eckstein, F; Hayashi, D; Guermazi, A;
Best Pract Res Clin Rheumatol. 2014; 28(1): 31-60.
Full papers/articles (Journal)
Association of thigh muscle strength with knee symptoms and radiographic disease stage of osteoarthritis: data from the osteoarthritis initiative.
Ruhdorfer, A; Wirth, W; Hitzl, W; Nevitt, M; Eckstein, F;
Arthritis Care Res (Hoboken). 2014; 66(9): 1344-1353.
Full papers/articles (Journal)
Thigh muscle cross-sectional areas and strength in knees with early vs knees without radiographic knee osteoarthritis: a between-knee, within-person comparison.
Ruhdorfer, AS; Dannhauer, T; Wirth, W; Cotofana, S; Roemer, F; Nevitt, M; Eckstein, F;
Osteoarthritis Cartilage. 2014; 22(10): 1634-1638.
Notes
Relative distribution of quadriceps head anatomical cross-sectional areas and volumes-Sensitivity to pain and to training intervention.
Sattler, M; Dannhauer, T; Ring-Dimitriou, S; Sänger, AM; Wirth, W; Hudelmaier, M; Eckstein, F;
Ann Anat. 2014; 196(6): 464-470.
Full papers/articles (Journal)
A novel methodology for generating 3D finite element models of the hip from 2D radiographs.
Thevenot, J; Koivumäki, J; Kuhn, V; Eckstein, F; Jämsä, T;
J Biomech. 2014; 47(2): 438-444.
Full papers/articles (Journal)
Longitudinal analysis of MR spin-spin relaxation times (T2) in medial femorotibial cartilage of adolescent vs mature athletes: dependence of deep and superficial zone properties on sex and age.
Wirth, W; Eckstein, F; Boeth, H; Diederichs, G; Hudelmaier, M; Duda, GN;
Osteoarthritis Cartilage. 2014; 22(10):1554-1558
Full papers/articles (Journal)
Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment--data from the Osteoarthritis Initiative.
Wirth, W; Nevitt, M; Hellio Le Graverand, MP; Lynch, J; Maschek, S; Hudelmaier, M; Eckstein, F;
Osteoarthritis Cartilage. 2014; 22(1):63-70
Full papers/articles (Journal)
Improving bone strength prediction in human proximal femur specimens through geometrical characterization of trabecular bone microarchitecture and support vector regression
Yang, CC; Nagarajan, MB; Huber, MB; Carballido-Gamio, J; Bauer, JS; Baum, T; Eckstein, F; Lochmuller, E; Majumdar, S; Link, TM; Wismuller, A
J ELECTRON IMAGING. 2014; 23(1): 013013
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
QUANTITATIVE MEASURES OF MENISCUS EXTRUSION PREDICT INCIDENT RADIOGRAPHIC KNEE OSTEOARTHRITIS-DATA FROM THE OSTEOARTHRITIS INITITATIVE
Bloecker, K; Quinn, E; Niu, J; Wirth, W; Eckstein, F; Felson, D
OSTEOARTHR CARTILAGE. 2014; 22: S250-S250.
Abstracts (Journal)
RELATIONSHIP BETWEEEN SUBREGIONAL LONGITUDINAL CARTILAGE LOSS AND MENISCUS POSITION IN KNEES WITH AND WITHOUT JOINT SPACE NARROWING - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Bloecker, K; Wirth, W; Guermazi, A; Resch, H; Hochreiter, J; Hunter, D; Eckstein, F
OSTEOARTHR CARTILAGE. 2014; 22: S244-S245.
Abstracts (Journal)
SUBREGIONAL KNEE CARTILAGE THINNING OR THICKENING IS AGE-DEPENDENT AND IS ASSOCIATED WITH SERUM BIOMARKERS IN ADOLESCENT AND MATURE VOLLEYBALL ATHLETES
Boeth, H; Duda, GN; Pramhed, A; Klint, C; Hed, J; Diederichs, G; Hudelmaier, M; Cotofana, S; Wirth, W; Hofmann-Amtenbrink, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2014; 22: S243-S243.
Abstracts (Journal)
DETECTING KNEE CARTILAGE THICKNESS CHANGE AT THREE AND SIX MONTHS
Buck, R; Le Graverand, MPH; Hudelmaier, M; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2014; 22: S67-S67.
Abstracts (Journal)
EFFICACY TRIALS FOR KNEE CARTILAGE CHANGE MAY ACHIEVE REASONABLE TREATMENT GOALS IN <= 12 MONTHS AND SAMPLE SIZE <= 200/ARM
Buck, R; Le Graverand, MPH; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2014; 22: S69-S69.
Abstracts (Journal)
Association Between Baseline External Knee Adduction and Flexion Moments during Gait and Medial Tibiofemoral Cartilage Thickness Loss over Two Years in Persons with Knee Osteoarthritis (OA).
Chang, AH; Moisio, KC; Eckstein, F; Chmiel, JS; Almagor, O; Prasad, P; Hayes, KW; Belisle, L; Zhang, YH; Rayahin, J; Sharma, L
ARTHRITIS RHEUMATOL. 2014; 66: S88-S88.
Abstracts (Journal)
KNEE CARTILAGE AND QUADRICEPS MUSCLE LOSS AFTER POSTERIOR CRUCIAL LIGAMENT (PCL) INJURY
Cotofana, S; Boeth, H; Wirth, W; Diederichs, G; Hudelmaier, M; Duda, G; Eckstein, F; Jung, T
OSTEOARTHR CARTILAGE. 2014; 22: S176-S176.
Abstracts (Journal)
CONTRALATERAL KNEE EFFECT ON FUNCTIONAL ASSESSMENTS - DATA FROM THE OSTEOARTHRITIS INITIATIVE (OAI)
Cotofana, S; Wirth, W; Guenther, O; Rossi, CP; Eckstein, F
OSTEOARTHR CARTILAGE. 2014; 22: S401-S401.
Abstracts (Journal)
CROSS SECTIONAL AND LONGITUDINAL RELATIONSHIP OF THIGH ADIPOSE TISSUE WITH KNEE PAIN, RADIOGRAPHIC OA STATUS, AND STRUCTURAL PROGRESSION - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Dannhauer, T; Ruhdorfer, A; Sattler, M; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2014; 22: S331-S331.
Abstracts (Journal)
SEX DIFFERENCES IN QUADRICEPS MUSCLE AND FEMORAL BONE CROSS SECTIONAL AREAS IN ADOLESCENT AND MATURE VOLLEYBALL ATHLETES
Eckstein, E; Boeth, H; Diederichs, G; Cotofana, S; Hudelmaier, M; Wirth, W; Hofmann-Amtenbrink, M; Duda, G
OSTEOARTHR CARTILAGE. 2014; 22: S317-S318.
Abstracts (Journal)
BE TT RESOLVED: PLAIN RADIOGRAPHY OR MRI - WHICH IS BETTER IN ASSESSING OUTCOME IN CLINICAL TRIALS?
Eckstein, F; Le Graverand, MPH
OSTEOARTHR CARTILAGE. 2014; 22: S4-S4.
Abstracts (Journal)
SUBREGIONAL BUT NOT TOTAL PLATE CARTILAGE CHANGE DIFFER BETWEEN EARLY AND LATE FOLLOW-UP AFTER ANTERIOR CRUCIATE LIGAMENT RUPTURE
Eckstein, F; Wirth, W; Lohmander, S; Hudelmaier, M; Frobell, R
OSTEOARTHR CARTILAGE. 2014; 22: S266-S267.
Abstracts (Journal)
THE RELATION BETWEEN SERUM COMP AND CILP CONCENTRATIONS AND MRI SUBREGIONAL CARTILAGE THICKNESS CHANGE OVER THE FIRST FIVE YEARS AFTER ACUTE ACL INJURY - DATA FROM THE KANON-TRIAL
Frobell, RB; Lohmander, S; Onnertjord, P; Heinegard, D; Struglics, A; Pramhed, A; Klint, C; Hed, J; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2014; 22: S354-S355.
Abstracts (Journal)
EFFECTS OF STRENGTH AND ENDURANCE TRAINING INTERVENTION ON THIGH INTERMUSCULAR AND SUBCUTANEOUS ADIPOSE TISSUE IN SARKOPENIC WOMEN
Griessmann, S; Dannhauer, T; Hudelmaier, M; Ruhdorfer, A; Wirth, W; Himmer, M; Ring-Dimitriou, S; Sanger, A; Kassmann, H; Pirich, C; Eckstein, F
OSTEOARTHR CARTILAGE. 2014; 22: S317-S317.
Abstracts (Journal)
CARTILAGE DAMAGE, BONE MARROW LESIONS AND MENISCAL LESIONS PREDICT QUANTITATIVELY MEASURED LOSS OF CARTILAGE OVER 30-MONTHS: THE MOST STUDY
Guermazi, A; Eckstein, F; Hayashi, D; Roemer, FW; Wirth, W; Yang, T; Niu, J; Sharma, L; Nevitt, MC; Lewis, CE; Torner, J; Felson, DT
OSTEOARTHR CARTILAGE. 2014; 22: S356-S356.
Abstracts (Journal)
THE PROJECTED NUMBERS OF TOTAL KNEE REPLACEMENT IN AUSTRIA - FROM 2010 TO 2075
Hitzl, W; Sattler, M; Eckstein, F; Cotofana, S
OSTEOARTHR CARTILAGE. 2014; 22: S216-S217.
Abstracts (Journal)
Preliminary Assessment of Predictive Validity of Cartilage Thickness MRI Biomarkers in Knee OA - the Fnih OA Biomarkers Consortium.
Hunter, DJ; Collins, JE; Nevitt, MC; Lynch, JA; Kraus, VB; Katz, JN; Losina, E; Roemer, F; Guermazi, A; Wirth, W; Eckstein, F
ARTHRITIS RHEUMATOL. 2014; 66: S87-S88.
Abstracts (Journal)
THE ROLE OF INCIDENT KNEE INJURY OR KNEE SURGERY AS PREDICTORS OF SUBSEQUENT RADIOGRAPHIC OSTEOARTHRITIS: DATA FROM THE OSTEOARTHRITIS INITIATIVE
Kwoh, C; Hannon, MJ; Fujii, T; Wang, Z; Hunter, DJ; Guermazi, A; Roemer, F; Eckstein, F; Grago, J; Boudreau, R
OSTEOARTHR CARTILAGE. 2014; 22: S211-S211.
Abstracts (Journal)
CHANGES IN JOINT LOADS, LEPTIN, AND MMP-3 SUBSEQUENT TO LONG-TERM INTENSIVE WEIGHT LOSS AND EXERCISE: SECONDARY OUTCOMES FROM THE INTENSIVE DIET AND EXERCISE FOR ARTHRITIS RANDOMIZED CLINICAL TRIAL
Messier, SP; DeVita, P; Nicklas, BJ; Beavers, D; Miller, GD; Hunter, DJ; Eckstein, F; Guermazi, A; Loeser, RF
OSTEOARTHR CARTILAGE. 2014; 22: S83-S84.
Abstracts (Journal)
MRI-BASED LONG TERM PREDICITION OF INCIDENT RADIOGRAPHIC OSTEOARTHRITIS
Roemer, FW; Kwoh, CK; Fujii, T; Hunter, DJ; Boudreau, R; Eckstein, F; Hannon, MJ; Guermazi, A
ANN RHEUM DIS. 2014; 73: 108-108.
Abstracts (Journal)
DECLINE OF THIGH MUSCLE CROSS-SECTIONAL AREAS IN CHRONICALLY PAINFUL VS. MATCHED PAINLESS KNEES: DATA FROM THE OSTEOARTHRITIS INITIATIVE
Ruhdorfer, AS; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2014; 22: S327-S328.
Abstracts (Journal)
Does Unilateral Knee Pain lead to a difference in muscle strength compared to bilateral painful knees? – Data from the Osteoarthritis Initiative (OAI).
Steidle, E; Wirth, W; Ruhdorfer, A; Cotofana, S; Segal, NA; Eckstein, F;
Abstracts (Journal)
DOES PAIN IN ONE KNEE AFFECT MEASUREMENT OF ISOMETRIC MUSCLE STRENGTH IN THE CONTRALATERAL LIMB? - DATA FROM THE OSTEOARTHRITIS INITIATIVE (OAI)
Steidle, E; Wirth, W; Ruhrdorfer, A; Cotofana, S; Segal, NA; Eckstein, F
OSTEOARTHR CARTILAGE. 2014; 22: S408-S408.
Abstracts (Journal)
LONGITUDINAL, LAYER-SPECIFIC CARTILAGE COMPOSITION CHANGE (T2) DURING MATURATION AND DEGENERATION
Wirth, W; Boeth, H; Diederichs, G; Hudelmaier, M; Hofmann-Amtenbrink, M; Eckstein, F; Jung, T; Duda, G
OSTEOARTHR CARTILAGE. 2014; 22: S267-S268.
Abstracts (Journal)
Relationship of Buckling and Knee Injury to Pain Exacerbation in Knee Osteoarthritis: A Web-Based Case-Crossover Stud.
Zobel, I; Erfani, T; Bennell, K; Makovey, J; Metcalf, B; Chen, JS; March, L; Zhang, YQ; Eckstein, F; Hunter, DJ
ARTHRITIS RHEUMATOL. 2014; 66: S560-S561.
Abstracts (Journal)
2013
Journal Articles
Cortical and trabecular bone structure analysis at the distal radius-prediction of biomechanical strength by DXA and MRI.
Baum, T; Kutscher, M; Müller, D; Räth, C; Eckstein, F; Lochmüller, EM; Rummeny, EJ; Link, TM; Bauer, JS;
J Bone Miner Metab. 2013; 31(2):-21
Full papers/articles (Journal)
Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing - data from the Osteoarthritis Initiative.
Bloecker, K; Guermazi, A; Wirth, W; Benichou, O; Kwoh, CK; Hunter, DJ; Englund, M; Resch, H; Eckstein, F;
Osteoarthritis Cartilage. 2013; 21(3): 419-427.
Full papers/articles (Journal)
Contribution of regional 3D meniscus and cartilage morphometry by MRI to joint space width in fixed flexion knee radiography--a between-knee comparison in subjects with unilateral joint space narrowing.
Bloecker, K; Wirth, W; Hunter, DJ; Duryea, J; Guermazi, A; Kwoh, CK; Resch, H; Eckstein, F;
Eur J Radiol. 2013; 82(12): e832-e839.
Full papers/articles (Journal)
Femorotibial Cartilage Thickness Change Distributions for Subjects without Signs, Symptoms, or Risk Factors of Knee Osteoarthritis
Buck, RJ; Dreher, D; Eckstein, F;
Cartilage. 2013; 3(4): 305-313.
Full papers/articles (Journal)
Frequency and spatial distribution of cartilage thickness change in knee osteoarthritis and its relation to clinical and radiographic covariates - data from the osteoarthritis initiative.
Buck, RJ; Wirth, W; Dreher, D; Nevitt, M; Eckstein, F;
Osteoarthritis Cartilage. 2013; 21(1): 102-109.
Full papers/articles (Journal)
Relationship between knee pain and the presence, location, size and phenotype of femorotibial denuded areas of subchondral bone as visualized by MRI.
Cotofana, S; Wyman, BT; Benichou, O; Dreher, D; Nevitt, M; Gardiner, J; Wirth, W; Hitzl, W; Kwoh, CK; Eckstein, F; Frobell, RB;
Osteoarthritis Cartilage. 2013; 21(9): 1214-1222.
Full papers/articles (Journal)
Baseline and longitudinal change in isometric muscle strength prior to radiographic progression in osteoarthritic and pre-osteoarthritic knees - data from the Osteoarthritis Initiative.
Eckstein, F; Hitzl, W; Duryea, J; Kent Kwoh, C; Wirth, W;
Osteoarthritis Cartilage. 2013; 21(5):682-690
Full papers/articles (Journal)
Quantitative MRI measures of cartilage predict knee replacement: a case-control study from the Osteoarthritis Initiative.
Eckstein, F; Kwoh, CK; Boudreau, RM; Wang, Z; Hannon, MJ; Cotofana, S; Hudelmaier, MI; Wirth, W; Guermazi, A; Nevitt, MC; John, MR; Hunter, DJ;
Ann Rheum Dis. 2013; 72(5): 707-714.
Full papers/articles (Journal)
Imaging of osteoarthritis.
Guermazi, A; Hayashi, D; Eckstein, F; Hunter, DJ; Duryea, J; Roemer, FW;
Rheum Dis Clin North Am. 2013; 39(1): 67-105.
Full papers/articles (Journal)
Imaging biomarker validation and qualification report: sixth OARSI Workshop on Imaging in Osteoarthritis combined with third OA Biomarkers Workshop.
Hunter, DJ; Eckstein, F; Kraus, VB; Losina, E; Sandell, L; Guermazi, A;
Osteoarthritis Cartilage. 2013; 21(7): 939-942.
Full papers/articles (Journal)
Subchondral Bone Trabecular Integrity Predicts and Changes Concurrently With Radiographic and Magnetic Resonance Imaging-Determined Knee Osteoarthritis Progression
Kraus, VB; Feng, S; Wang, SC; White, S; Ainslie, M; Le Graverand, MPH; Brett, A; Eckstein, F; Hunter, DJ; Lane, NE; Taljanovic, MS; Schnitzer, T; Charles, HC
ARTHRITIS RHEUM-US. 2013; 65(7): 1812-1821.
Full papers/articles (Journal)
Effects of Intensive Diet and Exercise on Knee Joint Loads, Inflammation, and Clinical Outcomes Among Overweight and Obese Adults With Knee Osteoarthritis The IDEA Randomized Clinical Trial
Messier, SP; Mihalko, SL; Legault, C; Miller, GD; Nicklas, BJ; DeVita, P; Beavers, DP; Hunter, DJ; Lyles, MF; Eckstein, F; Williamson, JD; Carr, JJ; Guermazi, A; Loeser, RF
JAMA-J AM MED ASSOC. 2013; 310(12): 1263-1273.
Full papers/articles (Journal)
Quantification of bone marrow lesion volume and volume change using semi-automated segmentation: data from the osteoarthritis initiative.
Pang, JC; Driban, JB; Destenaves, G; Miller, E; Lo, GH; Ward, RJ; Price, LL; Lynch, JA; Eaton, CB; Eckstein, F; McAlindon, TE
BMC Musculoskelet Disord. 2013; 14:3
Full papers/articles (Journal)
Scaling relations between trabecular bone volume fraction and microstructure at different skeletal sites.
Räth, C; Baum, T; Monetti, R; Sidorenko, I; Wolf, P; Eckstein, F; Matsuura, M; Lochmüller, EM; Zysset, PK; Rummeny, EJ; Link, TM; Bauer, JS;
Bone. 2013; 57(2): 377-383.
Full papers/articles (Journal)
Thigh muscle cross-sectional areas and strength in advanced versus early painful osteoarthritis: an exploratory between-knee, within-person comparison in osteoarthritis initiative participants.
Ruhdorfer, A; Dannhauer, T; Wirth, W; Hitzl, W; Kwoh, CK; Guermazi, A; Hunter, DJ; Benichou, O; Eckstein, F
Arthritis Care Res (Hoboken). 2013; 65(7):103-142
Full papers/articles (Journal)
Trabecular homogeneity index derived from plain radiograph to evaluate bone quality.
Thevenot, J; Hirvasniemi, J; Finnilä, M; Pulkkinen, P; Kuhn, V; Link, T; Eckstein, F; Jämsä, T; Saarakkala, S;
J Bone Miner Res. 2013; 28(12): 2584-2591.
Full papers/articles (Journal)
Meniscus body position, size, and shape in persons with and persons without radiographic knee osteoarthritis: quantitative analyses of knee magnetic resonance images from the osteoarthritis initiative.
Wenger, A; Wirth, W; Hudelmaier, M; Noebauer-Huhmann, I; Trattnig, S; Bloecker, K; Frobell, RB; Kwoh, CK; Eckstein, F; Englund, M;
Arthritis Rheum. 2013; 65(7): 1804-1811.
Full papers/articles (Journal)
Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis.
Wiegant, K; van Roermund, PM; Intema, F; Cotofana, S; Eckstein, F; Mastbergen, SC; Lafeber, FP;
Osteoarthritis Cartilage. 2013; 21(11): 1660-1667.
Full papers/articles (Journal)
Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative.
Wirth, W; Duryea, J; Hellio Le Graverand, MP; John, MR; Nevitt, M; Buck, RJ; Eckstein, F;
Osteoarthritis Cartilage. 2013; 21(1): 117-125.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
CORRELATION OF RADIOLOGICAL ESTIMATES OF MENISCUS EXTRUSION (MOAKS) WITH QUANTITATIVE TIBIAL COVERAGE IN KNEES WITH AND WITHOUT JOINT SPACE NARROWING - RESULTS FROM THE OSTEOARTHRITIS INITIATIVE
Bloecker, K; Guermazi, A; Wirth, W; Kwoh, KC; Resch, H; Hunter, DJ; Eckstein, F
OSTEOARTHR CARTILAGE. 2013; 21: S178-S179.
Abstracts (Journal)
MENISCUS BODY POSITION IN THE NORMAL KNEE AND ITS CHANGE OVER 4 YEARS
Bruns, K; Svensson, F; Turkiewicz, A; Wirth, W; Guermazi, A; Eckstein, F; Englund, M
OSTEOARTHR CARTILAGE. 2013; 21: S51-S52.
Abstracts (Journal)
BASELINE VARUS THRUST AND 3-YEAR INCREASE IN DENUDED SUBCHONDRAL BONE IN PERSONS WITH OR AT HIGHER RISK FOR KNEE OSTEOARTHRITIS (OA)
Chang, AH; Chmiel, JS; Almagor, O; Eckstein, F; Hayes, K; Moisio, KC; Nevitt, M; Kwoh, K; Hochberg, M; Eaton, C; Bathon, J; Jackson, R; Dunlop, D; Sharma, L
OSTEOARTHR CARTILAGE. 2013; 21: S245-S245.
Abstracts (Journal)
IS THE RISK OF INCIDENT RADIOGRAPHIC KNEE OA RELATED TO SEVERITY OF CONTRA-LATERAL RADIOGRAPHIC KNEE STATUS?-DATA FROM THE OSTEOARTHRITIS INITIATIVE
Cotofana, S; Wirth, W; Kwoh, KC; Hunter, DJ; Duryea, J; Eckstein, F
OSTEOARTHR CARTILAGE. 2013; 21: S58-S59.
Abstracts (Journal)
Longitudinal Femorotibial Cartilage Thickness Increase In Young Athletes At The End Of Adolescence
Eckstein, F; Boeth, H; Diederichs, G; Wirth, W; Hudelmaier, M; Cotofana, S; Duda, G
ARTHRITIS RHEUM-US. 2013; 65: S98-S98.
Abstracts (Journal)
TRAJECTORY OF CARTILAGE LOSS WITHIN 4 YEARS PRIOR TO KNEE REPLACEMENT: A NESTED CASE CONTROL STUDY FROM THE OSTEOARTHRITIS INITIATIVE
Eckstein, F; Boudreau, R; Wang, Z; Hannon, M; Wirth, W; Guermazi, A; Roemer, F; Nevitt, M; John, M; Ladel, C; Hunter, D; Kwoh, C
OSTEOARTHR CARTILAGE. 2013; 21: S174-S174.
Abstracts (Journal)
Trajectory Of Cartilage Thickness Change During The Years Prior To Knee Replacement: Data From The Osteoarthritis Initiative.
Eckstein, F; Boudreau, RM; Wang, ZJ; Hannon, MJ; Wirth, W; Cotofana, S; Guermazi, A; Roemer, F; Nevitt, MC; John, M; Ladel, C; Hunter, DJ; Kwoh, CK
ARTHRITIS RHEUM-US. 2013; 65: S1176-S1176.
Abstracts (Journal)
AGE- AND SEX-DEPENDENCE OF FEMOROTIBIAL CARTILAGE CHANGE AFTER ANTERIOR CRUCIATE LIGAMENT (ACL) TEAR-5 YEAR FOLLOW UP IN THE KANON STUDY
Eckstein, F; Wirth, W; Lohmander, L; Hudelmaier, M; Frobell, R
OSTEOARTHR CARTILAGE. 2013; 21: S113-S113.
Abstracts (Journal)
Semiquantitative MRI Features Of Knee Osteoarthritis Show Compartment-Specific Relationships With Quantitative Cartilage Thickness Loss: The Multicenter Osteoarthritis Study.
Guermazi, A; Eckstein, F; Hayashi, D; Roemer, F; Wirth, W; Yang, TZ; Niu, JB; Sharma, L; Nevitt, MC; Lewis, CE; Torner, J; Felson, DT
ARTHRITIS RHEUM-US. 2013; 65: S478-S478.
Abstracts (Journal)
MEDIAL MENISCAL DAMAGE AND EXTRUSION INCREASE RISK OF INCIDENT RADIOGRAPHIC OSTEOARTHRITIS
Guermazi, A; Kwoh, CK; Hannon, MJ; Hunter, DJ; Boudreau, R; Eckstein, F; Grago, J; Wang, Z; Roemer, FW
ANN RHEUM DIS. 2013; 72: 748-749.
Abstracts (Journal)
LOCATION-INDEPENDANT ANALYSIS OF INTRAARTICULAR SPRIFERMIN EFFECTS ON CARTILAGE STRUCTURE USING ORDERED VALUES
Hellot, S; Wirth, W; Guermazi, A; Rossi, CP; Eckstein, F
OSTEOARTHR CARTILAGE. 2013; 21: S32-S33.
Abstracts (Journal)
CARTILAGE THICKNESS LOSS AND INCIDENCE OF KNEE REPLACEMENT IN A SUBSAMPLE FROM THE OSTEOARTHRITIS INITIATIVE - A PROSPECTIVE COHORT STUDY
Hitzl, W; Wirth, W; Maschek, S; Cotofana, S; Nevitt, M; John, M; Ladel, C; Eckstein, F
OSTEOARTHR CARTILAGE. 2013; 21: S249-S250.
Abstracts (Journal)
LONGITUDINAL RATES OF CHANGE IN SUBCHONDRAL BONE SIZE IN HEALTHY KNEES AND KNEES WITH RADIOGRAPHIC OSTEOARTHRITIS
Hudelmaier, M; Wirth, W; Nevitt, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2013; 21: S242-S242.
Abstracts (Journal)
Kellgren-Lawrence Grade (KL) 0 Vs. KL 1 Knees Differ in Their Magnetic Resonance Imaging Predictors of Subsequent Radiographic Osteoarthritis
Kwoh, CK; Guermazi, A; Fujii, T; Boudreau, RM; Hannon, M; Grago, J; Hunter, D; Eckstein, F; Roemer, F
ARTHRITIS RHEUM-US. 2013; 65(12): 3328-3328.
Abstracts (Journal)
RATES AND SENSITIVITY OF KNEE CARTILAGE LOSS IN RADIOGRAPHIC DISEASE STRATA - CENTRAL VERSUS SITE READINGS FROM THE OSTEOARTHRITIS INITIATIVE
Maschek, S; Wirth, W; Nevitt, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2013; 21: S183-S184.
Abstracts (Journal)
LARGE AREAS OF CARTILAGE DAMAGE AND FULL THICKNESS CARTILAGE LOSS INCREASE RISK FOR INCIDENT RADIOGRAPHIC OSTEOARTHRITIS
Roemer, FW; Guermazi, A; Hannon, MJ; Eckstein, F; Hunter, DJ; Boudreau, R; Wang, Z; Grago, J; Kwoh, CK
ANN RHEUM DIS. 2013; 72: 695-695.
Abstracts (Journal)
MEDIAL MENISCAL PATHOLOGY INCREASES RISK OF INCIDENT RADIOGRAPHIC OSTEOARTHRITIS: A MATCHED CASE-CONTROL STUDY FROM THE OSTEOARTHRITIS INITIATIVE
Roemer, FW; Kwoh, C; Hannon, MJ; Hunter, DJ; Boudreau, RM; Eckstein, F; Wang, Z; Guermazi, A
OSTEOARTHR CARTILAGE. 2013; 21: S175-S176.
Abstracts (Journal)
SUBCHONDRAL BONE MARROW LESIONS PREDICT INCIDENT RADIOGRAPHIC OSTEOARTHRITIS
Roemer, FW; Kwoh, CK; Hannon, MJ; Boudreau, R; Hunter, DJ; Eckstein, F; Wang, Z; Grago, J; Guermazi, A
ANN RHEUM DIS. 2013; 72: 104-104.
Abstracts (Journal)
PAIN HAS A STRONGER ASSOCIATION WITH THIGH MUSCLE STRENGTH THAN THE RADIOGRAPHIC STAGE OF KNEE OSTEOARTHRITIS - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Ruhdorfer, AS; Wirth, W; Hitzl, W; Nevitt, MC; Eckstein, F
OSTEOARTHR CARTILAGE. 2013; 21: S218-S219.
Abstracts (Journal)
SPECIFIC MUSCLE STRENGTH IS REDUCED IN FEMALE KNEES WITH INCIDCENCE RADIOGRAPHIC OSTEOARTHRITIS
Sattler, M; Niu, J; Dannhauer, T; Wirth, W; Felson, D; Eckstein, F
OSTEOARTHR CARTILAGE. 2013; 21: S220-S220.
Abstracts (Journal)
Does Change In Femorotibial Cartilage Thickness Differ Between Acutely Anterior-Cruciate Ligament Injured Knees Treated With and Without Reconstructive Surgery
Wirth, W; Eckstein, F; Hudelmaier, M; Lohmander, S; Frobell, R
ARTHRITIS RHEUM-US. 2013; 65: S1139-S1139.
Abstracts (Journal)
DOES CARTILAGE THICKNESS CHANGE DIFFER BETWEEN ACL DEFICIENT KNEES WITH AND WITHOUT RECONSTRUCTION SURGERY
Wirth, W; Eckstein, F; Hudelmaier, M; Lohmander, S; Frobell, R
OSTEOARTHR CARTILAGE. 2013; 21: S33-S34.
Abstracts (Journal)
2012
Journal Articles
Morphometric differences between the medial and lateral meniscus in healthy men - a three-dimensional analysis using magnetic resonance imaging.
Bloecker, K; Wirth, W; Hudelmaier, M; Burgkart, R; Frobell, R; Eckstein, F;
Cells Tissues Organs. 2012; 195(4): 353-364.
Full papers/articles (Journal)
Cartilage thickening in early radiographic knee osteoarthritis: a within-person, between-knee comparison.
Cotofana, S; Buck, R; Wirth, W; Roemer, F; Duryea, J; Nevitt, M; Eckstein, F;
Arthritis Care Res (Hoboken). 2012; 64(11): 1681-1690.
Full papers/articles (Journal)
How do short-term rates of femorotibial cartilage change compare to long-term changes? Four year follow-up data from the osteoarthritis initiative.
Eckstein, F; Mc Culloch, CE; Lynch, JA; Nevitt, M; Kwoh, CK; Maschek, S; Hudelmaier, M; Sharma, L; Wirth, W;
Osteoarthritis Cartilage. 2012; 20(11): 1250-1257.
Full papers/articles (Journal)
Recent advances in osteoarthritis imaging-the Osteoarthritis Initiative.
Eckstein, F; Wirth, W; Nevitt, MC;
Nat Rev Rheumatol. 2012; 8(10):622-630
Full papers/articles (Journal)
Different thresholds for detecting osteophytes and joint space narrowing exist between the site investigators and the centralized reader in a multicenter knee osteoarthritis study--data from the Osteoarthritis Initiative.
Guermazi, A; Hunter, DJ; Li, L; Benichou, O; Eckstein, F; Kwoh, CK; Nevitt, M; Hayashi, D;
Skeletal Radiol. 2012; 41(2):179-186
Full papers/articles (Journal)
Hand joint space narrowing and osteophytes are associated with magnetic resonance imaging-defined knee cartilage thickness and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative.
Haugen, IK; Cotofana, S; Englund, M; Kvien, TK; Dreher, D; Nevitt, M; Lane, NE; Eckstein, F;
J Rheumatol. 2012; 39(1): 161-166.
Full papers/articles (Journal)
Comparison between different implementations of the 3D FLASH sequence for knee cartilage quantification.
Hudelmaier, M; Glaser, C; Pfau, C; Eckstein, F;
MAGN RESON MATER PHY. 2012; 25(4): 305-312.
Full papers/articles (Journal)
Ct-based finite element models can be used to estimate experimentally measured failure loads in the proximal femur.
Koivumäki, JE; Thevenot, J; Pulkkinen, P; Kuhn, V; Link, TM; Eckstein, F; Jämsä, T;
Bone. 2012; 50(4):824-829
Full papers/articles (Journal)
Cortical bone finite element models in the estimation of experimentally measured failure loads in the proximal femur.
Koivumäki, JE; Thevenot, J; Pulkkinen, P; Kuhn, V; Link, TM; Eckstein, F; Jämsä, T;
Bone. 2012; 51(4):737-740
Full papers/articles (Journal)
The susceptibility of the femoral neck to fracture: an assessment incorporating the effects of age-remodeling and stress reduction.
Lee, T; Rammohan, AV; Chan, A; Tan, VB; Das De, S; Link, TM; Eckstein, F; Schafer, BW;
J Biomech. 2012; 45(6):931-937
Full papers/articles (Journal)
Side differences of thigh muscle cross-sectional areas and maximal isometric muscle force in bilateral knees with the same radiographic disease stage, but unilateral frequent pain - data from the osteoarthritis initiative.
Sattler, M; Dannhauer, T; Hudelmaier, M; Wirth, W; Sänger, AM; Kwoh, CK; Hunter, DJ; Eckstein, F;
Osteoarthritis Cartilage. 2012; 20(6): 532-540.
Full papers/articles (Journal)
Equivalence and precision of knee cartilage morphometry between different segmentation teams, cartilage regions, and MR acquisitions.
Schneider, E; Nevitt, M; McCulloch, C; Cicuttini, FM; Duryea, J; Eckstein, F; Tamez-Pena, J;
Osteoarthritis Cartilage. 2012; 20(8):86-79
Full papers/articles (Journal)
Interobserver reproducibility of quantitative meniscus analysis using coronal multiplanar DESS and IWTSE MR imaging
Siorpaes, K; Wenger, A; Bloecker, K; Wirth, W; Hudelmaier, M; Eckstein, F
MAGN RESON MED. 2012; 67(5): 1419-1426.
Full papers/articles (Journal)
Nocturnal changes in knee cartilage thickness in young healthy adults.
Sitoci, KH; Hudelmaier, M; Eckstein, F;
Cells Tissues Organs. 2012; 196(2): 189-194.
Full papers/articles (Journal)
Relationship of 3D meniscal morphology and position with knee pain in subjects with knee osteoarthritis: a pilot study.
Wenger, A; Englund, M; Wirth, W; Hudelmaier, M; Kwoh, K; Eckstein, F;
Eur Radiol. 2012; 22(1): 211-220.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
QUANTIFICATION OF TIBIAL COVERAGE, MENISCUS POSITION AND MENISCUS SIZE IN KNEES WITH AND WITHOUT JOINT SPACE NARROWING - DATA FROM THE OA INITIATIVE
Bloecker, K; Wirth, W; Benichou, O; Kwoh, C; Guermazi, A; Hunter, D; Englund, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2012; 20: S201-S202.
Abstracts (Journal)
A Virtual Knee Joint Replacement Clinical Endpoint Based On Longitudinal Trends and Thresholds in Koos Knee Pain and Function in Osteoarthritis Initiative Participants.
Boudreau, RM; Hunter, DJ; Wang, ZJ; Roemer, F; Eckstein, F; Hannon, MJ; Guermazi, A; Kwoh, CK
ARTHRITIS RHEUM-US. 2012; 64(10): S1040-S1041.
Abstracts (Journal)
LONGITUDINAL CHANGES IN CARTILAGE THICKNESS IN KNEES WITH OSTEOPHYTES BUT NO JOINT SPACE NARROWING VERSUS CONTRALATERAL KNEES WITHOUT RADIOGRAPHIC OA
Cotofana, S; Buck, R; Dreher, D; Wirth, W; Roemer, F; Duryea, J; Nevitt, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2012; 20: S208-S208.
Abstracts (Journal)
COMPARISON OF MUSCLE AREA AND STRENGTH BETWEEN OA KNEES WITH AND WITHOUT STRUCTURAL PROGRESSION - DATA FROM THE OA INITIATIVE
Dannhauer, T; Sattler, M; Wirth, W; Hunter, DJ; Kwoh, CK; Eckstein, F
OSTEOARTHR CARTILAGE. 2012; 20: S221-S222.
Abstracts (Journal)
CARTILAGE LOSS, MEASURED WITH MRI, PREDICTS KNEE REPLACEMENT - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Eckstein, F; Kwoh, CK; Boudreau, R; Wang, Z; Hannon, MJ; Cotofana, S; Hudelmaier, M; Wirth, W; Guermazi, A; Nevitt, M; John, MR; Hunter, DJ
OSTEOARTHR CARTILAGE. 2012; 20: S12-S12.
Abstracts (Journal)
Does Structural Progression of Knee Osteoarthritis Measured with Magnetic Resonance Imaging or Radiography Predict Knee Replacement?-Data From the Osteoarthritis Initiative.
Eckstein, F; Kwoh, CK; Boudreau, RM; Wang, ZJ; Hannon, MJ; Wirth, W; Guermazi, A; Roemer, F; Nevitt, MC; John, MR; Sharma, L; Duryea, JW; Hunter, DJ
ARTHRITIS RHEUM-US. 2012; 64(10): S1041-S1041.
Abstracts (Journal)
QUANTITATIVE MAGNETIC-RESONANCE-IMAGING MEASURES OF CARTILAGE PREDICT KNEE REPLACEMENT - A CASE-CONTROL STUDY FROM THE OSTEOARTHRITIS INITIATIVE
Eckstein, F; Kwoh, K; Boudreau, R; Wang, Z; Hannon, M; Cotofana, S; Wirth, W; Guermazi, A; Nevitt, M; John, M; Hunter, D
INTERN MED J. 2012; 42: 3-4.
Abstracts (Journal)
HOFFA-SYNOVITIS AND EFFUSION-SYNOVITIS ARE ASSOCIATED WITH KNEES UNDERGOING TOTAL KNEE REPLACEMENT: DATA FROM THE OSTEOARTHRITIS INITIATIVE
Guermazi, A; Kwoh, CK; Hannon, MJ; Boudreau, B; Hayashi, D; Hunter, DJ; Eckstein, F; John, MR; Wang, Z; Roemer, FW
OSTEOARTHR CARTILAGE. 2012; 20: S235-S236.
Abstracts (Journal)
The Intensive Diet and Exercise for Arthritis Trial (IDEA): 18-Month Radiographic and MRI Outcomes.
Hunter, DJ; Beavers, D; Eckstein, F; Guermazi, A; Loeser, RF; Nicklas, BJ; Mihalko, S; Miller, GD; Lyles, M; DeVita, P; Legault, C; Carr, JJ; Williamson, JD; Messier, SP
ARTHRITIS RHEUM-US. 2012; 64(10): S1070-S1070.
Abstracts (Journal)
DOES ANKLE CARTILAGE ADAPT TO STRONG ALTERATIONS IN LOADING ENVIRONMENT AFTER TRANSPLANTATION TO THE KNEE (VAN NEES ROTATIONPLASTY)?
Maschek, S; Eckstein, F; Wirth, W; Gradl, G; Kirchhoff, C; Wortler, K; von Eisenhart-Rothe, R
OSTEOARTHR CARTILAGE. 2012; 20: S219-S220.
Abstracts (Journal)
THE INTENSIVE DIET AND EXERCISE FOR ARTHRITIS TRIAL (IDEA): EFFECTS ON KNEE JOINT LOADING AND INFLAMMATION
Messier, SP; DeVita, P; Nicklas, BJ; Beavers, D; Mihalko, S; Miller, GD; Lyles, M; Hunter, DJ; Eckstein, F; Legault, C; Williamson, JD; Carr, JJ; Loeser, RF
OSTEOARTHR CARTILAGE. 2012; 20: S28-S28.
Abstracts (Journal)
Incident and Worsening Cartilage Damage in the Lateral Compartment and Multiple Subregions Worsening in the Medial Compartment Increase the Risk for Knee Replacement - Data From the Osteoarthritis Initiative
Roemer, F; Kwoh, CK; Hannon, MJ; Boudreau, RM; Eckstein, F; Hunter, DJ; Wang, ZJ; John, MR; Guermazi, A
ARTHRITIS RHEUM-US. 2012; 64(10): S108-S108.
Abstracts (Journal)
Medial Subchondral Bone Marrow Lesions Increase the Odds of Knee Joint Replacement-Data From the Osteoarthritis Initative
Roemer, F; Kwoh, CK; Hunter, D; Hannon, MJ; Boudreau, RM; Eckstein, F; Wang, ZJ; John, MR; Guermazi, A
ARTHRITIS RHEUM-US. 2012; 64(10): S108-S108.
Abstracts (Journal)
Presence of Severe Medial Mensical Pathology Increases the Odds for Knee Replacement: Data From the Osteoarthritis Initiative
Roemer, F; Kwoh, CK; Hunter, DJ; Boudreau, RM; Hannon, MJ; John, MR; Eckstein, F; Crema, M; Wang, ZJ; Guermazi, A
ARTHRITIS RHEUM-US. 2012; 64(10): S109-S109.
Abstracts (Journal)
KNEES WITH MEDIAL MENSICAL PATHOLOGY ARE MORE LIKELY TO UNDERGO TOTAL KNEE REPLACEMENT: A CROSS-SECTIONAL ANALYSIS FROM THE OSTEOARTHRITIS INITIATIVE
Roemer, FW; Kwoh, CK; Hunter, DJ; Boudreau, B; Hannon, MJ; Crema, MD; Eckstein, F; John, MR; Wang, Z; Guermazi, A
OSTEOARTHR CARTILAGE. 2012; 20: S220-S220.
Abstracts (Journal)
LARGE BONE MARROW LESIONS AND WORSENING OF BONE MARROW LESIONS IN THE MEDIAL TIBIO-FEMORAL COMPARTMENT ARE ASSOCIATED WITH KNEES UNDERGOING TOTAL KNEE REPLACEMENT : DATA FROM THE OSTEOARTHRITIS INITIATIVE
Roemer, FW; Kwoh, CK; Hunter, DJ; Boudreau, B; Hannon, MJ; Xu, L; Eckstein, F; Wang, Z; John, MR; Guermazi, A
OSTEOARTHR CARTILAGE. 2012; 20: S33-S34.
Abstracts (Journal)
THIGH MUSCLE CROSS-SECTIONAL AREAS AND STRENGTH ARE NOT REDUCED IN ADVANCED VERSUS EARLY PAINFUL KNEE OSTEOARTHRITIS - A BETWEEN-KNEE WITHIN-PERSON COMPARISON IN OAI PARTICIPANTS
Ruhdorfer, AS; Dannhauer, T; Wirth, W; Hudelmaier, M; Sattler, M; Kwoh, CK; Guermazi, A; Hunter, DJ; Benichou, O; Eckstein, F
OSTEOARTHR CARTILAGE. 2012; 20: S215-S215.
Abstracts (Journal)
EFFECTS OF TRAINING INTERVENTION ON QUADRICEPS HEADS IN UNTRAINED MIDDLE-AGED WOMEN
Sattler, M; Dannhauer, T; Ring-Dimitriou, S; Saenger, AM; Wirth, W; Hudelmaier, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2012; 20: S230-S230.
Abstracts (Journal)
RELATIONSHIP BETWEEN LATERAL JOINT SPACE NARROWING AND CHANGE IN KNEE CARTILAGE THICKNESS: DATA FROM THE OA INITIATIVE
Wirth, W; Nevitt, M; Le Graverand, MPH; Lynch, J; Maschek, S; Hudelmaier, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2012; 20: S212-S213.
Abstracts (Journal)
Book chapters
Simulating Bone Atrophy and Its Effects on the Structure and Stability of the Trabecular Bone.
Rath, C; Sidorenko, I; Monetti, R; Bauer, J; Baum, T; Matsuura, M; Zysset, P; Eckstein, F;
In: Dyonisiotis, Y; editors(s). Osteoporosis. InTech; p. 695-710. (ISBN: 978-953-51-0026-3)
2011
Journal Articles
Revision 1 size and position of the healthy meniscus, and its correlation with sex, height, weight, and bone area- a cross-sectional study.
Bloecker, K; Englund, M; Wirth, W; Hudelmaier, M; Burgkart, R; Frobell, RB; Eckstein, F;
BMC Musculoskelet Disord. 2011; 12: 248-1-248-9.
Full papers/articles (Journal)
Using ordered values of subregional cartilage thickness change increases sensitivity in detecting risk factors for osteoarthritis progression.
Buck, RJ; Wyman, BT; Hellio Le Graverand, MP; Hunter, D; Vignon, E; Wirth, W; Eckstein, F;
Osteoarthritis Cartilage. 2011; 19(3):302-308
Full papers/articles (Journal)
Subregional effects of meniscal tears on cartilage loss over 2 years in knee osteoarthritis.
Chang, A; Moisio, K; Chmiel, JS; Eckstein, F; Guermazi, A; Almagor, O; Cahue, S; Wirth, W; Prasad, P; Sharma, L;
Ann Rheum Dis. 2011; 70(1):74-79
Full papers/articles (Journal)
In vivo measures of cartilage deformation: patterns in healthy and osteoarthritic female knees using 3T MR imaging.
Cotofana, S; Eckstein, F; Wirth, W; Souza, RB; Li, X; Wyman, B; Hellio-Le Graverand, MP; Link, T; Majumdar, S;
Eur Radiol. 2011; 21(6): 1127-1135.
Full papers/articles (Journal)
Articular cartilage in the knee: current MR imaging techniques and applications in clinical practice and research.
Crema, MD; Roemer, FW; Marra, MD; Burstein, D; Gold, GE; Eckstein, F; Baum, T; Mosher, TJ; Carrino, JA; Guermazi, A;
Radiographics. 2011; 31(1): 37-61.
Reviews
Greater rates of cartilage loss in painful knees than in pain-free knees after adjustment for radiographic disease stage: data from the osteoarthritis initiative.
Eckstein, F; Cotofana, S; Wirth, W; Nevitt, M; John, MR; Dreher, D; Frobell, R;
Arthritis Rheum. 2011; 63(8): 225-267.
Full papers/articles (Journal)
Clinical, radiographic, molecular and MRI-based predictors of cartilage loss in knee osteoarthritis.
Eckstein, F; Le Graverand, MP; Charles, HC; Hunter, DJ; Kraus, VB; Sunyer, T; Nemirovskyi, O; Wyman, BT; Buck, R;
Ann Rheum Dis. 2011; 70(7): 122-130.
Full papers/articles (Journal)
Rates of change and sensitivity to change in cartilage morphology in healthy knees and in knees with mild, moderate, and end-stage radiographic osteoarthritis: results from 831 participants from the Osteoarthritis Initiative.
Eckstein, F; Nevitt, M; Gimona, A; Picha, K; Lee, JH; Davies, RY; Dreher, D; Benichou, O; Le Graverand, MP; Hudelmaier, M; Maschek, S; Wirth, W;
ARTHRIT CARE RES. 2011; 63(3): 311-319.
Full papers/articles (Journal)
Quantitative cartilage imaging in knee osteoarthritis.
Eckstein, F; Wirth, W;
Arthritis. 2011; 2011: 475684
Full papers/articles (Journal)
Definition of osteoarthritis on MRI: results of a Delphi exercise.
Hunter, DJ; Arden, N; Conaghan, PG; Eckstein, F; Gold, G; Grainger, A; Guermazi, A; Harvey, W; Jones, G; Hellio Le Graverand, MP; Laredo, JD; Lo, G; Losina, E; Mosher, TJ; Roemer, F; Zhang, W;
Osteoarthritis Cartilage. 2011; 19(8): 963-969.
Reviews
From joint anatomy to clinical outcomes in osteoarthritis and cartilage repair: summary of the fifth annual osteoarthritis imaging workshop.
Hunter, DJ; Eckstein, F;
Osteoarthritis Cartilage. 2011; 19(11):1263-1269
keine Übereinstimmung
Multiplanar Reconstruction Recovers Morphological Cartilage Assessment Reproducibility from Maloriented Coronal MRI Scans
Inglis, D; Wong, AKO; Eckstein, F; Adachi, JD; Beattie, KA
MAGN RESON MED. 2011; 65(3): 790-795.
Full papers/articles (Journal)
Tissue structure modification in knee osteoarthritis by use of joint distraction: an open 1-year pilot study.
Intema, F; Van Roermund, PM; Marijnissen, AC; Cotofana, S; Eckstein, F; Castelein, RM; Bijlsma, JW; Mastbergen, SC; Lafeber, FP;
Ann Rheum Dis. 2011; 70(8): 1441-1446.
Full papers/articles (Journal)
Varus-valgus alignment: reduced risk of subsequent cartilage loss in the less loaded compartment.
Moisio, K; Chang, A; Eckstein, F; Chmiel, JS; Wirth, W; Almagor, O; Prasad, P; Cahue, S; Kothari, A; Sharma, L;
Arthritis Rheum. 2011; 63(4): 1002-1009.
Full papers/articles (Journal)
Knee articular cartilage damage in osteoarthritis: analysis of MR image biomarker reproducibility in ACRIN-PA 4001 multicenter trial.
Mosher, TJ; Zhang, Z; Reddy, R; Boudhar, S; Milestone, BN; Morrison, WB; Kwoh, CK; Eckstein, F; Witschey, WR; Borthakur, A;
Radiology. 2011; 258(3): 83-42.
Full papers/articles (Journal)
Computational finite element bone mechanics accurately predicts mechanical competence in the human radius of an elderly population.
Mueller, TL; Christen, D; Sandercott, S; Boyd, SK; van Rietbergen, B; Eckstein, F; Lochmüller, EM; Müller, R; van Lenthe, GH;
Bone. 2011; 48(6): 1232-1238.
Full papers/articles (Journal)
Deformational behaviour of knee cartilage and changes in serum cartilage oligomeric matrix protein (COMP) after running and drop landing.
Niehoff, A; Müller, M; Brüggemann, L; Savage, T; Zaucke, F; Eckstein, F; Müller-Lung, U; Brüggemann, GP;
Osteoarthritis Cartilage. 2011; 19(8): 1003-1010.
Full papers/articles (Journal)
Assessing methods for characterising local and global structural and biomechanical properties of the trabecular bone network.
Sidorenko, I; Monetti, R; Bauer, J; Mueller, D; Rummeny, E; Eckstein, F; Matsuura, M; Lochmueller, EM; Zysset, P; Raeth, C;
Curr Med Chem. 2011; 18(22): 3402-3409.
Reviews
Micro-morphometrical assessment of the effect of Harpagophytum procumbens extract on articular cartilage in rabbits with experimental osteoarthritis using magnetic resonance imaging.
Wachsmuth, L; Lindhorst, E; Wrubel, S; Hadzhiyski, H; Hudelmaier, M; Eckstein, F; Chrubasik, S;
Phytother Res. 2011; 25(8): 1133-1140.
Full papers/articles (Journal)
MRI-based extended ordered values more efficiently differentiate cartilage loss in knees with and without joint space narrowing than region-specific approaches using MRI or radiography - data from the OA initiative
Wirth, W; Buck, R; Nevitt, M; Le Graverand, MPH; Benichou, O; Dreher, D; Davies, RY; Lee, JH; Picha, K; Gimona, A; Maschek, S; Hudelmaier, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2011; 19(6): 689-699.
Full papers/articles (Journal)
Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative.
Wirth, W; Larroque, S; Davies, RY; Nevitt, M; Gimona, A; Baribaud, F; Lee, JH; Benichou, O; Wyman, BT; Hudelmaier, M; Maschek, S; Eckstein, F;
OSTEOARTHR CARTILAGE. 2011; 19(1): 74-83.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Quantitative Assessment of cartilage using MRI and its relation to OA
Eckstein, F
SEMIN ARTHRITIS RHEU. 2011; 41(1): 91-92.
Abstracts (Journal)
The Intensive Diet and Exercise for Arthritis Trial: 18-Month Clinical Outcomes.
Messier, SP; Nicklas, BJ; Legault, C; Mihalko, S; Miller, GD; DeVita, P; Lyles, M; Hunter, DJ; Eckstein, F; Williamson, JD; Carr, JJ; Loeser, RF
ARTHRITIS RHEUM-US. 2011; 63(10): S281-S281.
Abstracts (Journal)
The relation between localized buckling and yield of the femoral neck
Rammohan, AV; Lee, T; Tan, VBC; Das De, S; Chan, A; Schafer, BW; Beck, TJ; Eckstein, F
BONE. 2011; 48: S173-S173.
Abstracts (Journal)
Prolonged Improvement of Clinical Status and Structural Cartilage Tissue Repair by Joint Distraction in Treatment of End-Stage Knee Osteoarthritis; The 2 Years Follow-up Data
Wiegant, K; Intema, F; van Roermund, P; Marijnissen, ACA; Cotofana, S; Eckstein, F; Mastbergen, SC; Lafeber, F
ARTHRITIS RHEUM-US. 2011; 63(10): S325-S326.
Abstracts (Journal)
2010
Journal Articles
Automated 3D trabecular bone structure analysis of the proximal femur-prediction of biomechanical strength by CT and DXA
Baum, T; Carballido-Gamio, J; Huber, MB; Muller, D; Monetti, R; Rath, C; Eckstein, F; Lochmuller, EM; Majumdar, S; Rummeny, EJ; Link, TM; Bauer, JS
OSTEOPOROSIS INT. 2010; 21(9): 1553-1564.
Full papers/articles (Journal)
One-year change in radiographic joint space width in patients with unilateral joint space narrowing: data from the Osteoarthritis Initiative.
Benichou, OD; Hunter, DJ; Nelson, DR; Guermazi, A; Eckstein, F; Kwoh, K; Myers, SL; Wirth, W; Duryea, J;
Arthritis Care Res (Hoboken). 2010; 62(7):924-931
Full papers/articles (Journal)
Osteoarthritis may not be a one-way-road of cartilage loss--comparison of spatial patterns of cartilage change between osteoarthritic and healthy knees.
Buck, RJ; Wyman, BT; Le Graverand, MP; Hudelmaier, M; Wirth, W; Eckstein, F;
OSTEOARTHR CARTILAGE. 2010; 18(3): 329-335.
Full papers/articles (Journal)
An efficient subset of morphological measures for articular cartilage in the healthy and diseased human knee.
Buck, RJ; Wyman, BT; Le Graverand, MP; Wirth, W; Eckstein, F;
MAGN RESON MED. 2010; 63(3): 68-90.
Full papers/articles (Journal)
Correlation between single-slice muscle anatomical cross-sectional area and muscle volume in thigh extensors, flexors and adductors of perimenopausal women
Cotofana, S; Hudelmaier, M; Wirth, W; Himmer, M; Ring-Dimitriou, S; Sanger, AM; Eckstein, F
EUR J APPL PHYSIOL. 2010; 110(1): 91-97.
Full papers/articles (Journal)
Effects of Exercise Intervention on Knee Morphology in Middle-Aged Women: A Longitudinal Analysis Using Magnetic Resonance Imaging
Cotofana, S; Ring-Dimitriou, S; Hudelmaier, M; Himmer, M; Wirth, W; Sanger, AM; Eckstein, F
CELLS TISSUES ORGANS. 2010; 192(1): 64-72.
Full papers/articles (Journal)
The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period.
Crema, MD; Guermazi, A; Li, L; Nogueira-Barbosa, MH; Marra, MD; Roemer, FW; Eckstein, F; Le Graverand, MPH; Wyman, BT; Hunter, DJ
Osteoarthritis Cartilage. 2010; 18(3):336-343
Full papers/articles (Journal)
Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis - data from the Osteoarthritis Initiative (OAI)
Eckstein, F; Wirth, W; Hunter, DJ; Guermazi, A; Kwoh, CK; Nelson, DR; Benichou, O
OSTEOARTHR CARTILAGE. 2010; 18(6): 760-768.
Full papers/articles (Journal)
Reference values and Z-scores for subregional femorotibial cartilage thickness--results from a large population-based sample (Framingham) and comparison with the non-exposed Osteoarthritis Initiative reference cohort.
Eckstein, F; Yang, M; Guermazi, A; Roemer, FW; Hudelmaier, M; Picha, K; Baribaud, F; Wirth, W; Felson, DT;
OSTEOARTHR CARTILAGE. 2010; 18(10): 1275-1283.
Full papers/articles (Journal)
Local bone enhancement fuzzy clustering for segmentation of MR trabecular bone images
Folkesson, J; Carballido-Gamio, J; Eckstein, F; Link, TM; Majumdar, S
MED PHYS. 2010; 37(1): 295-302.
Full papers/articles (Journal)
Assessment of Synovitis in the Osteoarthritic Knee: Comparison Between Manual Segmentation, Semiautomated Segmentation, and Semiquantitative Assessment Using Contrast-Enhanced Fat-Suppressed T(1)-Weighted MRI
Fotinos-Hoyer, AK; Guermazi, A; Jara, H; Eckstein, F; Ozonoff, A; Khard, H; Norbash, A; Bohndorf, K; Roemer, FW
MAGN RESON MED. 2010; 64(2): 604-609.
Full papers/articles (Journal)
Femorotibial Subchondral Bone Area and Regional Cartilage Thickness: A Cross-Sectional Description in Healthy Reference Cases and Various Radiographic Stages of Osteoarthritis in 1,003 Knees From the Osteoarthritis Initiative
Frobell, RB; Nevitt, MC; Hudelmaier, M; Wirth, W; Wyman, BT; Benichou, O; Dreher, D; Davies, R; Lee, JH; Baribaud, F; Gimona, A; Eckstein, F
ARTHRIT CARE RES. 2010; 62(11): 1612-1623.
Full papers/articles (Journal)
Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA - data from the OA initiative.
Frobell, RB; Wirth, W; Nevitt, M; Wyman, BT; Benichou, O; Dreher, D; Davies, RY; Lee, JH; Baribaud, F; Gimona, A; Hudelmaier, M; Cotofana, S; Eckstein, F;
OSTEOARTHR CARTILAGE. 2010; 18(5): 668-676.
Full papers/articles (Journal)
Effect of exercise intervention on thigh muscle volume and anatomical cross-sectional areas--quantitative assessment using MRI.
Hudelmaier, M; Wirth, W; Himmer, M; Ring-Dimitriou, S; Sänger, A; Eckstein, F;
MAGN RESON MED. 2010; 64(6): 1713-1720.
Full papers/articles (Journal)
Femorotibial cartilage morphology: reproducibility of different metrics and femoral regions, and sensitivity to change in disease.
Hudelmaier, M; Wirth, W; Wehr, B; Kraus, V; Wyman, BT; Hellio Le Graverand, MP; Eckstein, F;
CELLS TISSUES ORGANS. 2010; 192(5): 340-350.
Full papers/articles (Journal)
Does femoral strain distribution coincide with the occurrence of cervical versus trochanteric hip fractures? An experimental finite element study
Koivumaki, JEM; Thevenot, J; Pulkkinen, P; Salmi, JA; Kuhn, V; Lochmuller, EM; Link, TM; Eckstein, F; Jamsa, T
MED BIOL ENG COMPUT. 2010; 48(7): 711-717.
Full papers/articles (Journal)
Change in regional cartilage morphology and joint space width in osteoarthritis participants versus healthy controls: a multicentre study using 3.0 Tesla MRI and Lyon-Schuss radiography
Le Graverand, MPH; Buck, RJ; Wyman, BT; Vignon, E; Mazzuca, SA; Brandt, KD; Piperno, M; Charles, HC; Hudelmaier, M; Hunter, DJ; Jackson, C; Kraus, VB; Link, TM; Majumdar, S; Prasad, PV; Schnitzer, TJ; Vaz, A; Wirth, W; Eckstein, F
ANN RHEUM DIS. 2010; 69(1): 155-162.
Full papers/articles (Journal)
Does cartilage volume or thickness distinguish knees with and without mild radiographic osteoarthritis? The Framingham Study.
Reichenbach, S; Yang, M; Eckstein, F; Niu, J; Hunter, DJ; McLennan, CE; Guermazi, A; Roemer, F; Hudelmaier, M; Aliabadi, P; Felson, DT
Ann Rheum Dis. 2010; 69(1):143-149
Full papers/articles (Journal)
Assessment of the individual fracture risk of the proximal femur by using statistical appearance models.
Schuler, B; Fritscher, KD; Kuhn, V; Eckstein, F; Link, TM; Schubert, R;
Med Phys. 2010; 37(6): 2560-2571.
Full papers/articles (Journal)
Structural asymmetry between the hips and its relation to experimental fracture type.
Thevenot, J; Pulkkinen, P; Kuhn, V; Eckstein, F; Jämsä, T;
CALCIFIED TISSUE INT. 2010; 87(3): 203-210.
Full papers/articles (Journal)
The relationship between knee adduction moment and cartilage and meniscus morphology in women with osteoarthritis
Vanwanseele, B; Eckstein, F; Smith, RM; Lange, AK; Foroughi, N; Baker, MK; Shnier, R; Singh, MAF
OSTEOARTHR CARTILAGE. 2010; 18(7): 894-901.
Full papers/articles (Journal)
3D Bone Mineral Density Distribution and Shape Reconstruction of the Proximal Femur from a Single Simulated DXA Image: An In Vitro Study
Whitmarsh, T; Humbert, L; De Craene, M; Barquero, LMD; Fritscher, K; Schubert, R; Eckstein, F; Link, T; Frangi, AF
PROC SPIE. 2010; 7623:
Abstracts (Journal)
Spatial Patterns of Cartilage Loss in the Medial Femoral Condyle in Osteoarthritic Knees: Data From the Osteoarthritis Initiative
Wirth, W; Benichou, O; Kwoh, CK; Guermazi, A; Hunter, D; Putz, R; Eckstein, F
MAGN RESON MED. 2010; 63(3): 574-581.
Full papers/articles (Journal)
A three-dimensional quantitative method to measure meniscus shape, position, and signal intensity using MR images: a pilot study and preliminary results in knee osteoarthritis.
Wirth, W; Frobell, RB; Souza, RB; Li, X; Wyman, BT; Le Graverand, MP; Link, TM; Majumdar, S; Eckstein, F;
MAGN RESON MED. 2010; 63(5): 1162-1171.
Full papers/articles (Journal)
Sensitivity to change of cartilage morphometry using coronal FLASH, sagittal DESS, and coronal MPR DESS protocols--comparative data from the Osteoarthritis Initiative (OAI).
Wirth, W; Nevitt, M; Hellio Le Graverand, MP; Benichou, O; Dreher, D; Davies, RY; Lee, J; Picha, K; Gimona, A; Maschek, S; Hudelmaier, M; Eckstein, F;
OSTEOARTHR CARTILAGE. 2010; 18(4): 547-554.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
SELECTION OF COMPARABLE ANATOMICAL LOCATIONS OF MUSCLE CROSS-SECTIONAL IMAGES IN THE OSTEOARTHRITIS INITIATIVE MRI DATA
Dannhauer, T; Wirth, W; Eckstein, F
OSTEOARTHR CARTILAGE. 2010; 18: S195-S195.
Abstracts (Journal)
SIMULATION OF DRUG EFFECTS ON OA DISEASE PROGRESSION MEASURED WITH MRI - ORDERED VALUES ARE MORE SENSITIVE THAN ANALYSIS OF CARTILAGE PLATES AND SUBREGIONS
Eckstein, F; Wirth, W
OSTEOARTHR CARTILAGE. 2010; 18: S178-S178.
Abstracts (Journal)
MORPHOLOGIC DIFFERENCES BETWEEN POST-TRAUMATIC OA AND PRIMARY OA KNEES - DATA FROM THE OSTEOARTHRITIS INITIATIVE
Frobell, RB; Nevitt, M; Wirth, W; Hudelmaier, M; Gardiner, JL; Dreher, D; Eckstein, F
OSTEOARTHR CARTILAGE. 2010; 18: S18-S19.
Abstracts (Journal)
THE ASSOCIATION BETWEEN HEBERDENxxxS NODES AND FEMOROTIBIAL CARTILAGE LOSS IN SUBJECTS WITH PREVALENT OR AT HIGH RISK OF KNEE OSTEOARTHRITIS USING MR IMAGING - DATA FROM OAI
Haugen, IK; Cotofana, S; Englund, M; Kvien, TK; Wirth, W; Dreher, D; Nevitt, M; Lane, NE; Eckstein, F
OSTEOARTHR CARTILAGE. 2010; 18: S196-S196.
Abstracts (Journal)
DEFINITION OF OSTEOARTHRITIS ON MRI: RESULTS OF A DELPHI EXERCISE
Hunter, DJ; Arden, N; Conaghan, PG; Eckstein, F; Gold, G; Guermazi, A; Harvey, W; Jones, G; Le Graverand, MH; Laredo, JD; Lo, G; Losina, E; Mosher, TJ; Roemer, F; Zhang, W
OSTEOARTHR CARTILAGE. 2010; 18: S174-S175.
Abstracts (Journal)
TISSUE STRUCTURE MODIFICATION IN END-STAGE KNEE OSTEOARTHRITIS BY USE OF JOINT DISTRACTION
Intema, F; Wiegant, K; van Roermund, PM; Marijnissen, AC; Cotofona, S; Felix, E; Mastbergen, SM; Lafeber, FP
OSTEOARTHR CARTILAGE. 2010; 18: S142-S142.
Abstracts (Journal)
LONGITUDINAL SENSITIVITY TO CHANGE IN CARTILAGE MORPHOLOGY OF OAI KNEES - FROM HEALTHY REFERENCE TO LATE STAGE RADIOGRAPHIC OA
Maschek, S; Wehr, B; Wirth, W; Le Graverand, MPH; Benichou, O; Dreher, D; Davies, RY; Nevitt, M; Lee, J; Picha, K; Gimona, A; Hudelmaier, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2010; 18: S181-S181.
Abstracts (Journal)
EVALUATION OF THE TRABECULAR BONE CONTRIBUTION TO THE LOCAL BUCKLING STRENGTH OF THE FEMORAL NECK
Rammohan, AV; Lee, T; Tan, VBC; Schafer, BW; Beck, TJ; De, SD; Chan, A; Eckstein, F
OSTEOPOROSIS INT. 2010; 21: S664-S664.
Abstracts (Journal)
DIRECT COMPARISION OF ONE- AND TWO-YEAR SENSITIVITY TO CHANGE OF FIXED FLEXION RADIOGRAPHY VERSUS SUBREGIONAL MRI CARTILAGE MORPHOLOGY: DATA FROM THE OSTEOARTHRITIS INITATIVE
Wirth, W; Duryea, J; Nevitt, M; John, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2010; 18: S178-S178.
Abstracts (Journal)
Book chapters
Quantitative Morphological Imaging of the Knee Joint.
Eckstein, F; Carballido-Gamio, J;
In: Sharmila, M (Ed.) editors(s). Advances in MRI of the knee for Osteoarthritis.. p. 143-184.
Knochen, Gelenke, Muskeln.
Tillmann, BN; Eckstein, F
In: Zilles K, Tilmann BN editors(s). Anatomie. Heidelberg : Springer ; p. 76-94.
2009
Journal Articles
Quantitative MR imaging evaluation of the cartilage thickness and subchondral bone area in patients with ACL-reconstructions 7 years after surgery.
Andreisek, G; White, LM; Sussman, MS; Kunz, M; Hurtig, M; Weller, I; Essue, J; Marks, P; Eckstein, F;
OSTEOARTHR CARTILAGE. 2009; 17(7): 871-878.
Full papers/articles (Journal)
Advances of 3T MR imaging in visualizing trabecular bone structure of the calcaneus are partially SNR-independent: analysis using simulated noise in relation to micro-CT, 1.5T MRI, and biomechanical strength.
Bauer, JS; Monetti, R; Krug, R; Matsuura, M; Mueller, D; Eckstein, F; Rummeny, EJ; Lochmueller, EM; Raeth, CW; Link, TM;
J MAGN RESON IMAGING. 2009; 29(1): 132-140.
Full papers/articles (Journal)
Does the use of ordered values of subregional change in cartilage thickness improve the detection of disease progression in longitudinal studies of osteoarthritis?
Buck, RJ; Wyman, BT; Le Graverand, MP; Hudelmaier, M; Wirth, W; Eckstein, F;
ARTHRIT RHEUM-ARTHR. 2009; 61(7): 917-924.
Full papers/articles (Journal)
Geodesic topological analysis of trabecular bone microarchitecture from high-spatial resolution magnetic resonance images.
Carballido-Gamio, J; Krug, R; Huber, MB; Hyun, B; Eckstein, F; Majumdar, S; Link, TM;
MAGN RESON MED. 2009; 61(2): 448-456.
Full papers/articles (Journal)
Magnetic resonance imaging-based cartilage loss in painful contralateral knees with and without radiographic joint space narrowing: Data from the Osteoarthritis Initiative.
Eckstein, F; Benichou, O; Wirth, W; Nelson, DR; Maschek, S; Hudelmaier, M; Kwoh, CK; Guermazi, A; Hunter, D;
ARTHRIT RHEUM-ARTHR. 2009; 61(9): 1218-1225.
Full papers/articles (Journal)
Quantitative MR imaging of cartilage and trabecular bone in osteoarthritis.
Eckstein, F; Guermazi, A; Roemer, FW;
RADIOL CLIN N AM. 2009; 47(4): 655-673.
Reviews
Medial-to-Lateral Ratio of Tibiofemoral Subchondral Bone Area is Adapted to Alignment and Mechanical Load
Eckstein, F; Hudelmaier, M; Cahue, S; Marshall, M; Sharma, L
CALCIFIED TISSUE INT. 2009; 84(3): 186-194.
Full papers/articles (Journal)
One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort: association with sex, body mass index, symptoms and radiographic osteoarthritis status.
Eckstein, F; Maschek, S; Wirth, W; Hudelmaier, M; Hitzl, W; Wyman, B; Nevitt, M; Le Graverand, MP;
ANN RHEUM DIS. 2009; 68(5): 674-679.
Full papers/articles (Journal)
Relationship of compartment-specific structural knee status at baseline with change in cartilage morphology: a prospective observational study using data from the osteoarthritis initiative.
Eckstein, F; Wirth, W; Hudelmaier, MI; Maschek, S; Hitzl, W; Wyman, BT; Nevitt, M; Hellio Le Graverand, MP; Hunter, D;
Arthritis Res Ther. 2009; 11(3): R90
Full papers/articles (Journal)
Longitudinal quantitative MR imaging of cartilage morphology in the presence of gadopentetate dimeglumine (Gd-DTPA).
Eckstein, F; Wyman, BT; Buck, RJ; Wirth, W; Maschek, S; Hudelmaier, M; Le Graverand, MP;
MAGN RESON MED. 2009; 61(4): 975-980.
Full papers/articles (Journal)
Osteoarthritis: current role of imaging.
Guermazi, A; Eckstein, F; Hellio Le Graverand-Gastineau, MP; Conaghan, PG; Burstein, D; Keen, H; Roemer, FW;
MED CLIN N AM. 2009; 93(1): 101-126.
Full papers/articles (Journal)
Subregional femorotibial cartilage morphology in women--comparison between healthy controls and participants with different grades of radiographic knee osteoarthritis.
Hellio Le Graverand, MP; Buck, RJ; Wyman, BT; Vignon, E; Mazzuca, SA; Brandt, KD; Piperno, M; Charles, HC; Hudelmaier, M; Hunter, DJ; Jackson, C; Kraus, VB; Link, TM; Majumdar, S; Prasad, PV; Schnitzer, TJ; Vaz, A; Wirth, W; Eckstein, F;
OSTEOARTHR CARTILAGE. 2009; 17(9): 1177-1185.
Full papers/articles (Journal)
Relation of regional articular cartilage morphometry and meniscal position by MRI to joint space width in knee radiographs
Hunter, DJ; Buck, R; Vignon, E; Eckstein, F; Brandt, K; Mazzuca, SA; Wyman, BT; Otterness, I; Le Graverand, MPH
OSTEOARTHR CARTILAGE. 2009; 17(9): 1170-1176.
Full papers/articles (Journal)
Exercise and osteoarthritis.
Hunter, DJ; Eckstein, F;
J ANAT. 2009; 214(2): 19-207.
Reviews
Radiologic markers of osteoarthritis progression.
Hunter, DJ; Le Graverand, MP; Eckstein, F;
CURR OPIN RHEUMATOL. 2009; 21(2): 110-117.
Reviews
Assessing the susceptibility to local buckling at the femoral neck cortex to age-related bone loss.
Lee, T; Choi, JB; Schafer, BW; Segars, WP; Eckstein, F; Kuhn, V; Beck, TJ;
ANN BIOMED ENG. 2009; 37(9): 191-120.
Full papers/articles (Journal)
The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationale
Messier, SP; Legault, C; Mihalko, S; Miller, GD; Loeser, RF; DeVita, P; Lyles, M; Eckstein, F; Hunter, DJ; Williamson, JD; Nicklas, BJ
BMC MUSCULOSKEL DIS. 2009; 10:
Full papers/articles (Journal)
Denuded subchondral bone and knee pain in persons with knee osteoarthritis.
Moisio, K; Eckstein, F; Chmiel, JS; Guermazi, A; Prasad, P; Almagor, O; Song, J; Dunlop, D; Hudelmaier, M; Kothari, A; Sharma, L;
ARTHRITIS RHEUM. 2009; 60(12): 3703-3710.
Full papers/articles (Journal)
Non-invasive bone competence analysis by high-resolution pQCT: an in vitro reproducibility study on structural and mechanical properties at the human radius.
Mueller, TL; Stauber, M; Kohler, T; Eckstein, F; Müller, R; van Lenthe, GH;
BONE. 2009; 44(2): 364-371.
Full papers/articles (Journal)
Regional, age and gender differences in architectural measures of bone quality and their correlation to bone mechanical competence in the human radius of an elderly population.
Mueller, TL; van Lenthe, GH; Stauber, M; Gratzke, C; Eckstein, F; Müller, R;
Bone. 2009; 45(5):882-891
Full papers/articles (Journal)
Magnetic resonance imaging-based semiquantitative and quantitative assessment in osteoarthritis.
Roemer, FW; Eckstein, F; Guermazi, A;
RHEUM DIS CLIN N AM. 2009; 35(3): 521-555.
Reviews
Discrimination of cervical and trochanteric hip fractures using radiography-based two-dimensional finite element models.
Thevenot, J; Pulkkinnen, P; Koivumäki, J; Kuhn, V; Eckstein, F; Jämsä, T
The Open Bone Journal. 2009; 1: 16-22.
Full papers/articles (Journal)
MR imaging of cartilage and its repair in the knee--a review.
Trattnig, S; Domayer, S; Welsch, GW; Mosher, T; Eckstein, F;
EUR RADIOL. 2009; 19(7): 1582-1594.
Reviews
Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort
Wirth, W; Le Graverand, MPH; Wyman, BT; Maschek, S; Hudelmaier, M; Hitzl, W; Nevitt, M; Eckstein, F
OSTEOARTHR CARTILAGE. 2009; 17(3): 291-297.
Full papers/articles (Journal)
2008
Journal Articles
Quantitative imaging of musculoskeletal tissue.
Augat, P; Eckstein, F;
ANNU REV BIOMED ENG. 2008; 10: 36-90.
Reviews
Minimum joint space width and tibial cartilage morphology in the knees of healthy individuals: a cross-sectional study.
Beattie, KA; Duryea, J; Pui, M; O"Neill, J; Boulos, P; Webber, CE; Eckstein, F; Adachi, JD;
BMC Musculoskelet Disord. 2008; 9: 119
Full papers/articles (Journal)
Prediction of the fracture load of whole proximal femur specimens by topological analysis of the mineral distribution in DXA-scan images.
Boehm, HF; Horng, A; Notohamiprodjo, M; Eckstein, F; Burklein, D; Panteleon, A; Lutz, J; Reiser, M;
BONE. 2008; 43(5): 826-831.
Full papers/articles (Journal)
Precision of 3.0 Tesla quantitative magnetic resonance imaging of cartilage morphology in a multicentre clinical trial.
Eckstein, F; Buck, RJ; Burstein, D; Charles, HC; Crim, J; Hudelmaier, M; Hunter, DJ; Hutchins, G; Jackson, C; Kraus, VB; Lane, NE; Link, TM; Majumdar, LS; Mazzuca, S; Prasad, PV; Schnitzer, TJ; Taljanovic, MS; Vaz, A; Wyman, B; Le Graverand, MP;
ANN RHEUM DIS. 2008; 67(12): 1683-1688.
Full papers/articles (Journal)
Patterns of femorotibial cartilage loss in knees with neutral, varus, and valgus alignment.
Eckstein, F; Wirth, W; Hudelmaier, M; Stein, V; Lengfelder, V; Cahue, S; Marshall, M; Prasad, P; Sharma, L;
ARTHRIT RHEUM-ARTHR. 2008; 59(11): 1563-1570.
Full papers/articles (Journal)
Prediction of biomechanical parameters of the proximal femur using statistical appearance models and support vector regression.
Fritscher, K; Schuler, B; Link, T; Eckstein, F; Suhm, N; Hänni, M; Hengg, C; Schubert, R;
Med Image Comput Comput Assist Interv. 2008; 11(Pt 1): 568-575.
Full papers/articles (Journal)
Imaging in osteoarthritis.
Guermazi, A; Burstein, D; Conaghan, P; Eckstein, F; Hellio Le Graverand-Gastineau, MP; Keen, H; Roemer, FW;
Rheum Dis Clin North Am. 2008; 34(3):645-687
Reviews
Proximal femur specimens: automated 3D trabecular bone mineral density analysis at multidetector CT--correlation with biomechanical strength measurement.
Huber, MB; Carballido-Gamio, J; Bauer, JS; Baum, T; Eckstein, F; Lochmüller, EM; Majumdar, S; Link, TM;
RADIOLOGY. 2008; 247(2): 472-481.
Full papers/articles (Journal)
Premorbid knee osteoarthritis is not characterised by diffuse thinness: the Framingham Osteoarthritis Study.
Hunter, DJ; Niu, JB; Zhang, Y; LaValley, M; McLennan, CE; Hudelmaier, M; Eckstein, F; Felson, DT;
ANN RHEUM DIS. 2008; 67(11): 1545-1549.
Full papers/articles (Journal)
Measurement of trabecular bone microstructure does not improve prediction of mechanical failure loads at the distal radius compared with bone mass alone.
Lochmüller, EM; Kristin, J; Matsuura, M; Kuhn, V; Hudelmaier, M; Link, TM; Eckstein, F;
CALCIFIED TISSUE INT. 2008; 83(4): 293-299.
Full papers/articles (Journal)
Site-specific deterioration of trabecular bone architecture in men and women with advancing age.
Lochmüller, EM; Matsuura, M; Bauer, J; Hitzl, W; Link, TM; Müller, R; Eckstein, F;
J BONE MINER RES. 2008; 23(12): 1964-1973.
Full papers/articles (Journal)
Does thoracic or lumbar spine bone architecture predict vertebral failure strength more accurately than density?
Lochmüller, EM; Pöschl, K; Würstlin, L; Matsuura, M; Müller, R; Link, TM; Eckstein, F;
OSTEOPOROSIS INT. 2008; 19(4): 537-545.
Full papers/articles (Journal)
The role of fabric in the quasi-static compressive mechanical properties of human trabecular bone from various anatomical locations.
Matsuura, M; Eckstein, F; Lochmüller, EM; Zysset, PK;
Biomech Model Mechanobiol. 2008; 7(1):27-42
Full papers/articles (Journal)
Allometric relationships between knee cartilage volume, thickness, surface area and body dimensions.
Otterness, IG; Le Graverand, MP; Eckstein, F;
Osteoarthritis Cartilage. 2008; 16(1):3-40
Full papers/articles (Journal)
Experimental hip fracture load can be predicted from plain radiography by combined analysis of trabecular bone structure and bone geometry.
Pulkkinen, P; Jämsä, T; Lochmüller, EM; Kuhn, V; Nieminen, MT; Eckstein, F;
Osteoporos Int. 2008; 19(4):547-558
Full papers/articles (Journal)
Strength through structure: visualization and local assessment of the trabecular bone structure
Rath, C; Monetti, R; Bauer, J; Sidorenko, I; Muller, D; Matsuura, M; Lochmuller, EM; Zysset, P; Eckstein, F
NEW J PHYS. 2008; 10:
Full papers/articles (Journal)
Relationship of meniscal damage, meniscal extrusion, malalignment, and joint laxity to subsequent cartilage loss in osteoarthritic knees.
Sharma, L; Eckstein, F; Song, J; Guermazi, A; Prasad, P; Kapoor, D; Cahue, S; Marshall, M; Hudelmaier, M; Dunlop, D;
ARTHRITIS RHEUM. 2008; 58(6): 1716-1726.
Full papers/articles (Journal)
A technique for regional analysis of femorotibial cartilage thickness based on quantitative magnetic resonance imaging.
Wirth, W; Eckstein, F;
IEEE Trans Med Imaging. 2008; 27(6):737-744
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Differences in femorotibial cartilage morphology of knees with and without joint space narrowing vary by region
Eckstein, F; Benichou, O; Wirth, W; Nelson, DR; Maschek, S; Hudelmaier, M; Kwoh, K; Guermazi, A; Hunter, D
ARTHRITIS RHEUM. 2008; 58(9): S494-S494.
Abstracts (Journal)
The relationship of denuded subchondral bone area to knee pain severity and incident frequent knee pain
Moisio, K; Eckstein, F; Song, J; Cahue, S; Marshall, M; Dunlop, D; Sharma, L
ARTHRITIS RHEUM. 2008; 58(9): S237-S238.
Abstracts (Journal)
Do cartilage volume or thickness distinguish knees with and without mild radiographic osteoarthritis? The Framingham study
Reichenbach, S; Yang, M; Eckstein, F; Niu, J; Hunter, DJ; McLennan, CE; Guermazi, A; Roemer, F; Hudel-Maier, M; Aliabadi, P; Felson, DT
ARTHRITIS RHEUM. 2008; 58(9): S492-S493.
Abstracts (Journal)
Newspaper/magazine articles
Quantitative imaging of musculoskeletal tissue
Augat, P; Eckstein, F;
European Muskuloskeletal Review Touch Briefings . 2008.
Studying the effect of noise on the performance of 2D and 3D texture measures for quantifying the trabecular bone structure as obtained with high-resolution MR imaging at 3 Tesla.
Monetti, R; Bauer, J; Mueller, D; Rummeny, EJ; Link, TM; Majumdar, S; Matsuura, M; Eckstein, F; Sidorenko, I; Raeth, CW;
Medical Imaging 2008: Image Processing.
Proceedings of the SPIE 2008 2008; 6914: pp. 69144V69141-69149.
. 2008.
2007
Journal Articles
Quantitative imaging of cartilage morphology at 3.0 Tesla in the presence of gadopentate dimeglumine (Gd-DTPA).
Eckstein, F; Buck, RJ; Wyman, BT; Kotyk, JJ; Le Graverand, MP; Remmers, AE; Evelhoch, JL; Hudelmaier, M; Charles, HC;
MAGN RESON MED. 2007; 58(2): 402-406.
Full papers/articles (Journal)
Impact of coil design on the contrast-to-noise ratio, precision, and consistency of quantitative cartilage morphometry at 3 Tesla: a pilot study for the osteoarthritis initiative.
Eckstein, F; Kunz, M; Hudelmaier, M; Jackson, R; Yu, J; Eaton, CB; Schneider, E;
Magn Reson Med. 2007; 57(2): 448-454.
Full papers/articles (Journal)
Two year longitudinal change and test-retest-precision of knee cartilage morphology in a pilot study for the osteoarthritis initiative.
Eckstein, F; Kunz, M; Schutzer, M; Hudelmaier, M; Jackson, RD; Yu, J; Eaton, CB; Schneider, E;
OSTEOARTHR CARTILAGE. 2007; 15(11): 1326-1332.
Full papers/articles (Journal)
Sex differences of human trabecular bone microstructure in aging are site-dependent.
Eckstein, F; Matsuura, M; Kuhn, V; Priemel, M; Müller, R; Link, TM; Lochmüller, EM;
J Bone Miner Res. 2007; 22(6):817-824
Full papers/articles (Journal)
Imaging of knee osteoarthritis: data beyond the beauty.
Eckstein, F; Mosher, T; Hunter, D;
Curr Opin Rheumatol. 2007; 19(5):435-443
Reviews
Knee cartilage morphologic characteristics and muscle status of professional weight lifters and sprinters: a magnetic resonance imaging study.
Gratzke, C; Hudelmaier, M; Hitzl, W; Glaser, C; Eckstein, F;
AM J SPORT MED. 2007; 35(8): 1346-1353.
Full papers/articles (Journal)
Accuracy and test-retest precision of quantitative cartilage morphology on a 1.0 T peripheral magnetic resonance imaging system.
Inglis, D; Pui, M; Ioannidis, G; Beattie, K; Boulos, P; Adachi, JD; Webber, CE; Eckstein, F
Osteoarthritis Cartilage. 2007; 15(1):110-115
Full papers/articles (Journal)
Women have thinner cartilage and smaller joint surfaces than men after adjustment for body height and weight
Otterness, IG; Eckstein, F
OSTEOARTHR CARTILAGE. 2007; 15(6): 666-672.
Full papers/articles (Journal)
Fuzzy logic structure analysis of trabecular bone of the calcaneus to estimate proximal femur fracture load and discriminate subjects with and without vertebral fractures using high-resolution magnetic resonance imaging at 1.5 T and 3 T.
Patel, PV; Eckstein, F; Carballido-Gamio, J; Phan, C; Matsuura, M; Lochmüller, EM; Majumdar, S; Link, TM;
Calcif Tissue Int. 2007; 81(4):29-304
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
The contribution of medial femoral and tibial cartilage thickness to minimum joint space width in osteoarthritic knees
Beattie, KA; Duryea, J; Pui, M; OxxxNeill, J; Boulos, P; Webber, C; Eckstein, F; Adachi, JD
OSTEOPOROSIS INT. 2007; 18: S13-S13.
Abstracts (Journal)
Structural parameters of distal radius and ipsilateral ulna show good correlation
Goldhahn, J; Rutishauser, T; Mueller, TL; Eckstein, F; Trentz, O; Muller, R
CALCIFIED TISSUE INT. 2007; 80: S128-S128.
Abstracts (Journal)
Radiographic analysis of trabecular bone structure and bone geometry in the prediction of hip fracture load
Jamsa, TJ; Pulkkinen, P; Lochmuller, E; Kuhn, V; Nieminen, M; Eckstein, F
J BONE MINER RES. 2007; 22: S477-S477.
Abstracts (Journal)
Newspaper/magazine articles
Future directions in quantitative imaging of osteoarthritis.
Eckstein, F
European Musculoskeletal Review,Touch Briefings: London . 2007.
Determinanten mechanischer Kompetenz der Knochen.
Eckstein, F; Matsuura, M; Lochmüller, EM
Nova Acta Leopoldina NF 94, Nr 348, 89-99 . 2007.
Analyzing µCT images of bone specimen with wavelets and scaling indices: Which texture measure does better to depict the trabecular bone structure?
Raeth, CW; Bauer, J; Mueller, D; Rummeny, EJ; Link, TM; Majumdar, S; Eckstein, F; Monetti, R
SPIE - Medical Imaging 2007 Conference, Proceedings 2007; 6512 . 2007.
2006
Journal Articles
Structural analysis of trabecular bone of the proximal femur using multislice computed tomography: a comparison with dual X-ray absorptiometry for predicting biomechanical strength in vitro.
Bauer, JS; Kohlmann, S; Eckstein, F; Mueller, D; Lochmüller, EM; Link, TM;
Calcif Tissue Int. 2006; 78(2):7-89
Full papers/articles (Journal)
Detection of osteoporotic vertebral fractures using multidetector CT
Bauer, JS; Muller, D; Ambekar, A; Dobritz, M; Matsuura, M; Eckstein, F; Rummeny, EJ; Link, TM
OSTEOPOROSIS INT. 2006; 17(4): 608-615.
Full papers/articles (Journal)
Quantitative magnetic resonance imaging of osteoarthritis.
Eckstein, F
Future Rheumatology. 2006; 1: 699-715.
Full papers/articles (Journal)
Proposal for a nomenclature for magnetic resonance imaging based measures of articular cartilage in osteoarthritis.
Eckstein, F; Ateshian, G; Burgkart, R; Burstein, D; Cicuttini, F; Dardzinski, B; Gray, M; Link, TM; Majumdar, S; Mosher, T; Peterfy, C; Totterman, S; Waterton, J; Winalski, CS; Felson, D
Osteoarthritis Cartilage. 2006; 14(10):974-983
Full papers/articles (Journal)
Quantitative MRI of cartilage and bone: degenerative changes in osteoarthritis.
Eckstein, F; Burstein, D; Link, TM
NMR Biomed. 2006; 19(7):822-854
Reviews
Magnetic resonance imaging (MRI) of articular cartilage in knee osteoarthritis (OA): morphological assessment
Eckstein, F; Cicuttini, F; Raynauld, JP; Waterton, JC; Peterfy, C
OSTEOARTHR CARTILAGE. 2006; 14: A46-A75.
Proceedings Papers
The effects of exercise on human articular cartilage.
Eckstein, F; Hudelmaier, M; Putz, R;
J ANAT. 2006; 208(4): 491-512.
Reviews
Double echo steady state magnetic resonance imaging of knee articular cartilage at 3 Tesla: a pilot study for the Osteoarthritis Initiative.
Eckstein, F; Hudelmaier, M; Wirth, W; Kiefer, B; Jackson, R; Yu, J; Eaton, CB; Schneider, E;
Ann Rheum Dis. 2006; 65(4): 433-441.
Full papers/articles (Journal)
Parametric biomedical imaging - What defines the quality of quantitative radiological approaches?
Gluer, CC; Barkmann, R; Hahn, HK; Majumdar, S; Eckstein, F; Nickelsen, TN; Bolte, H; Dicken, V; Heller, M
ROFO-FORTSCHR RONTG. 2006; 178(12): 1187-1201.
Reviews
Effects of joint unloading and reloading on human cartilage morphology and function, muscle cross-sectional areas, and bone density - a quantitative case report.
Hudelmaier, M; Glaser, C; Hausschild, A; Burgkart, R; Eckstein, F;
J Musculoskelet Neuronal Interact. 2006; 6(3): 284-290.
Full papers/articles (Journal)
MRI protocols for whole-organ assessment of the knee in osteoarthritis.
Peterfy, CG; Gold, G; Eckstein, F; Cicuttini, F; Dardzinski, B; Stevens, R;
Osteoarthritis Cartilage. 2006; 14 Suppl A:A95-111
Reviews
Trabecular bone structure of the calcaneus: comparison of MR imaging at 3.0 and 1.5 T with micro-CT as the standard of reference.
Phan, CM; Matsuura, M; Bauer, JS; Dunn, TC; Newitt, D; Lochmueller, EM; Eckstein, F; Majumdar, S; Link, TM;
Radiology. 2006; 239(2):488-496
Full papers/articles (Journal)
Association of geometric factors and failure load level with the distribution of cervical vs. trochanteric hip fractures.
Pulkkinen, P; Eckstein, F; Lochmuller, EM; Kuhn, V; Jamsa, T
J Bone Miner Res. 2006; 21(6):895-901
Full papers/articles (Journal)
Femorotibial and patellar cartilage loss in patients prior to total knee arthroplasty, heterogeneity, and correlation with alignment of the knee
von Eisenhart-Rothe, R; Graichen, H; Hudelmaier, M; Vogl, T; Sharma, L; Eckstein, F
ANN RHEUM DIS. 2006; 65(1): 69-73.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Articular cartilage volume and thickness measurements correlate with pain and function in individuals with medial tibiofemoral knee OA
Beattie, K; Boulos, P; Inglis, D; Webber, C; Eckstein, F; Adachi, JD
OSTEOPOROSIS INT. 2006; 17: S10-S11.
Abstracts (Journal)
Medial tibial and femoral cartilage volume and thickness measurements correlate with pain and function in individuals with knee OA.
Beattie, K; Boulos, P; Inglis, D; Webber, CE; Eckstein, F; Adachi, JD
ARTHRITIS RHEUM-US. 2006; 54(9): S152-S152.
Abstracts (Journal)
What are the best imaging markers for osteoarthritis progression?
Eckstein, F
ANN RHEUM DIS. 2006; 65: 15-15.
Abstracts (Journal)
Longitudinal change in articular cartilage thickness and denuded area by alignment direction in persons with knee osteoarthritis.
Eckstein, F; Cahue, S; Marshall, M; Hudelmaier, M; Sharma, L
ARTHRITIS RHEUM. 2006; 54(9): S135-S136.
Abstracts (Journal)
Non-destructive prediction of individual bone strength as assessed by high-resolution 3D-pQCT in a population study of the human radius.
Mueller, TL; van Lenthe, GH; Stauber, M; Gratzke, C; Eckstein, F; Muller, R
J BONE MINER RES. 2006; 21: S232-S232.
Abstracts (Journal)
2005
Journal Articles
Improved performance of hip DXA using a novel region of interest in the upper part of the femoral neck: in vitro study using bone strength as a standard of reference.
Boehm, HF; Eckstein, F; Wunderer, C; Kuhn, V; Lochmueller, EM; Schreiber, K; Mueller, D; Rummeny, EJ; Link, TM;
J Clin Densitom. 2005; 8(4): 488-494.
Full papers/articles (Journal)
Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: a new model to study cortical and cancellous compartments in a single loaded element.
De Souza, RL; Matsuura, M; Eckstein, F; Rawlinson, SC; Lanyon, LE; Pitsillides, AA;
Bone. 2005; 37(6):810-818
Full papers/articles (Journal)
Accuracy and precision of quantitative assessment of cartilage morphology by magnetic resonance imaging at 3.0T.
Eckstein, F; Charles, HC; Buck, RJ; Kraus, VB; Remmers, AE; Hudelmaier, M; Wirth, W; Evelhoch, JL;
ARTHRITIS RHEUM. 2005; 52(10): 3132-3136.
Full papers/articles (Journal)
In vivo cartilage deformation after different types of activity and its dependence on physical training status.
Eckstein, F; Lemberger, B; Gratzke, C; Hudelmaier, M; Glaser, C; Englmeier, KH; Reiser, M;
ANN RHEUM DIS. 2005; 64(2): 291-295.
Full papers/articles (Journal)
Accuracy of quantitative magnetic resonance imaging in the detection of ex vivo focal cartilage defects.
Graichen, H; Al-Shamari, D; Hinterwimmer, S; von Eisenhart-Rothe, R; Vogl, T; Eckstein, F;
Ann Rheum Dis. 2005; 64(8):1120-1125
Full papers/articles (Journal)
Effect of abducting and adducting muscle activity on glenohumeral translation, scapular kinematics and subacromial space width in vivo.
Graichen, H; Hinterwimmer, S; von Eisenhart-Rothe, R; Vogl, T; Englmeier, KH; Eckstein, F;
J Biomech. 2005; 38(4):755-760
Full papers/articles (Journal)
In vivo contact areas of the knee in patients with patellar subluxation.
Hinterwimmer, S; Gotthardt, M; von Eisenhart-Rothe, R; Sauerland, S; Siebert, M; Vogl, T; Eckstein, F; Graichen, H;
J Biomech. 2005; 38(10):2095-2101
Full papers/articles (Journal)
Gender differences in trabecular bone architecture of the distal radius assessed with magnetic resonance imaging and implications for mechanical competence.
Hudelmaier, M; Kollstedt, A; Lochmüller, EM; Kuhn, V; Eckstein, F; Link, TM;
OSTEOPOROSIS INT. 2005; 16(9): 1124-1133.
Full papers/articles (Journal)
Use of novel interactive input devices for segmentation of articular cartilage from magnetic resonance images.
McWalter, EJ; Wirth, W; Siebert, M; von Eisenhart-Rothe, RM; Hudelmaier, M; Wilson, DR; Eckstein, F;
OSTEOARTHR CARTILAGE. 2005; 13(1): 48-53.
Reviews
Trabecular bone structure obtained from multislice spiral computed tomography of the calcaneus predicts osteoporotic vertebral deformities.
Patel, PV; Prevrhal, S; Bauer, JS; Phan, C; Eckstein, F; Lochmüller, EM; Majumdar, S; Link, TM;
J Comput Assist Tomogr. 2005; 29(2):246-253
Full papers/articles (Journal)
Pathomechanics in atraumatic shoulder instability - Scapular positioning correlates with humeral head centering
von Eisenhart-Rothe, R; Matsen, FA; Eckstein, F; Vogl, T; Graichen, H
CLIN ORTHOP RELAT R. 2005; (433): 82-89.
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
Detection of osteoporotic vertebral fractures: A comparison of radiographs and sagittal CT reformations
Bauer, JS; Mueller, D; Ambekar, A; Dobritz, M; Matsuura, M; Eckstein, F; Rummeny, EJ; Majumdar, S; Link, TM
J BONE MINER RES. 2005; 20(9): S264-S264.
Abstracts (Journal)
There is more denuded cartilage in the premorbid OA knee
Hunter, DJ; LaValley, M; McLennan, C; Hudelmaier, M; Eckstein, F; Felson, DT
ARTHRITIS RHEUM. 2005; 52(9): S66-S67.
Abstracts (Journal)
Book chapters
Quantitative anatomy of diarthrodial joint articular layers.
Ateshian, GA; Eckstein, F;
In: R. MVCH (Ed.) editors(s). Basic Orthopaedic Biomechanics..
2004
Journal Articles
[Multislice-CT for structure analysis of trabecular bone - a comparison with micro-CT and biomechanical strength].
Bauer, JS; Issever, AS; Fischbeck, M; Burghardt, A; Eckstein, F; Rummeny, EJ; Majumdar, S; Link, TM;
ROFO-FORTSCHR RONTG. 2004; 176(5): 709-718.
Full papers/articles (Journal)
Multislice computed tomography of the distal radius metaphysis: relationship of cortical bone structure with gender, age, osteoporotic status, and mechanical competence.
Bonel, HM; Lochmüller, EM; Well, H; Kuhn, V; Hudelmaier, M; Reiser, M; Eckstein, F;
J CLIN DENSITOM. 2004; 7(2): 169-182.
Full papers/articles (Journal)
Determinants and heterogeneity of mechanical competence throughout the thoracolumbar spine of elderly women and men.
Eckstein, F; Fischbeck, M; Kuhn, V; Link, TM; Priemel, M; Lochmüller, EM;
Bone. 2004; 35(2):36-74
Full papers/articles (Journal)
Measuring cartilage morphology with quantitative magnetic resonance imaging.
Eckstein, F; Glaser, C;
Semin Musculoskelet Radiol. 2004; 8(4):329-353
Reviews
Strength prediction of the distal radius by bone densitometry--evaluation using biomechanical tests.
Eckstein, F; Kuhn, V; Lochmüller, EM;
Ann Biomed Eng. 2004; 32(3):487-503
Reviews
Correlation and sex differences between ankle and knee cartilage morphology determined by quantitative magnetic resonance imaging.
Eckstein, F; Siedek, V; Glaser, C; Al-Ali, D; Englmeier, KH; Reiser, M; Graichen, H;
Ann Rheum Dis. 2004; 63(11):1490-1495
Full papers/articles (Journal)
Longitudinal in vivo effects of growth hormone overexpression on bone in transgenic mice.
Eckstein, F; Weusten, A; Schmidt, C; Wehr, U; Wanke, R; Rambeck, W; Wolf, E; Mohan, S;
J Bone Miner Res. 2004; 19(5):802-810
Full papers/articles (Journal)
Reproducibility and side differences of mechanical tests for determining the structural strength of the proximal femur.
Eckstein, F; Wunderer, C; Boehm, H; Kuhn, V; Priemel, M; Link, TM; Lochmüller, EM;
J Bone Miner Res. 2004; 19(3):379-385
Full papers/articles (Journal)
Quantitative assessment of cartilage status in osteoarthritis by quantitative magnetic resonance imaging: technical validation for use in analysis of cartilage volume and further morphologic parameters.
Graichen, H; von Eisenhart-Rothe, R; Vogl, T; Englmeier, KH; Eckstein, F;
Arthritis Rheum. 2004; 50(3):811-816
Full papers/articles (Journal)
Toward imaging biomarkers for osteoarthritis
Gray, ML; Eckstein, F; Peterfy, C; Dahlberg, L; Kim, YJ; Sorensen, AG
CLIN ORTHOP RELAT R. 2004; (427): S175-S181.
Proceedings Papers
Cartilage atrophy in the knees of patients after seven weeks of partial load bearing.
Hinterwimmer, S; Krammer, M; Krötz, M; Glaser, C; Baumgart, R; Reiser, M; Eckstein, F;
Arthritis Rheum. 2004; 50(8):2516-2520
Full papers/articles (Journal)
The osteoporotic vertebral structure is well adapted to the loads of daily life, but not to infrequent "error" loads
Homminga, J; Van-Rietbergen, B; Lochmuller, EM; Weinans, H; Eckstein, F; Huiskes, R
BONE. 2004; 34(3): 510-516.
Full papers/articles (Journal)
Can geometry-based parameters from pQCT and material parameters from quantitative ultrasound (QUS) improve the prediction of radial bone strength over that by bone mass (DXA)?
Hudelmaier, M; Kuhn, V; Lochmüller, EM; Well, H; Priemel, M; Link, TM; Eckstein, F;
OSTEOPOROSIS INT. 2004; 15(5): 375-381.
Full papers/articles (Journal)
Trabecular bone structure of the distal radius, the calcaneus, and the spine: which site predicts fracture status of the spine best?
Link, TM; Bauer, J; Kollstedt, A; Stumpf, I; Hudelmaier, M; Settles, M; Majumdar, S; Lochmüller, EM; Eckstein, F;
INVEST RADIOL. 2004; 39(8): 487-497.
Full papers/articles (Journal)
Technical considerations for microstructural analysis of human trabecular bone from specimens excised from various skeletal sites.
Nägele, E; Kuhn, V; Vogt, H; Link, TM; Müller, R; Lochmüller, EM; Eckstein, F;
Calcif Tissue Int. 2004; 75(1):15-22
Full papers/articles (Journal)
Image-based micro-finite-element modeling for improved distal radius strength diagnosis: moving from bench to bedside.
Pistoia, W; van Rietbergen, B; Lochmüller, EM; Lill, CA; Eckstein, F; Rüegsegger, P;
J CLIN DENSITOM. 2004; 7(2): 153-160.
Full papers/articles (Journal)
In vivo precision of quantitative shoulder cartilage measurements, and changes after spinal cord injury.
Vanwanseele, B; Eckstein, F; Hadwighorst, H; Knecht, H; Spaepen, A; Stüssi, E;
Magn Reson Med. 2004; 51(5):1026-1030
Full papers/articles (Journal)
Femoro-tibial and menisco-tibial translation patterns in patients with unilateral anterior cruciate ligament deficiency--a potential cause of secondary meniscal tears.
von Eisenhart-Rothe, R; Bringmann, C; Siebert, M; Reiser, M; Englmeier, KH; Eckstein, F; Graichen, H;
J Orthop Res. 2004; 22(2):275-282
Full papers/articles (Journal)
Conference papers, proceedings, abstracts
High resolution spiral-CT for the assessment of osteoporosis: Which site of the spine and region of the vertebra is best suited to obtain trabecular bone structural parameters?
Bauer, JS; Mueller, D; Fischbeck, M; Eckstein, F; Rummeny, EJ; Link, TM
J BONE MINER RES. 2004; 19: S169-S169.
Abstracts (Journal)
Non-invasive axial loading of the murine tibia induces increases in cortical bone formation accompanied by modification in trabecular bone architecture: A novel model for in vivo loading studies.
de Souza, RL; Matsuura, M; Eckstein, F; Rawlinson, SCF; Lanyon, LE; Pitsillides, AA
J BONE MINER RES. 2004; 19: S259-S259.
Abstracts (Journal)
Improved precision of quantitative cartilage measurements with magnetic resonance imaging at 3 T
Eckstein, F; Buck, RJ; Charles, HC; Hudelmaier, M; Wirth, W; Kraus, VB; Evelhoch, JL
OSTEOARTHR CARTILAGE. 2004; 12: S119-S119.
Abstracts (Journal)
MR-technique for assessment of cartilage contact areas in patients with patellar subluxation
Graichen, H; Hinterwimmer, S; von Eisenhart-Rothe, R; Eckstein, F
OSTEOARTHR CARTILAGE. 2004; 12: S117-S118.
Abstracts (Journal)
Links between varus-valgus alignment, cartilage morphology and three-dimensional patellar kinematics in early knee osteoarthritis
McWalter, EJ; Cibere, J; Nicolaou, S; Eckstein, F; Wilson, DR
OSTEOARTHR CARTILAGE. 2004; 12: S60-S61.
Abstracts (Journal)
Book chapters
Non-invasive study of human cartilage structure by MRI.
Eckstein, F;
In: Pastoureau, P. DCFSM (Ed.) editors(s). Osteoarthritis: methods and protocols.. p. 191-218.
2003
Journal Articles
Feasibility of T and Z scores from magnetic resonance imaging data for quantification of cartilage loss in osteoarthritis.
Burgkart, R; Glaser, C; Hinterwimmer, S; Hudelmaier, M; Englmeier, KH; Reiser, M; Eckstein, F;
ARTHRITIS RHEUM. 2003; 48(10): 2829-2835.
Full papers/articles (Journal)
Quantitative image analysis: software systems in drug development trials.
Eckstein, F; Englmeier, KH;
DRUG DISCOV TODAY. 2003; 8(20): 922-923.
Notes
Femoro-tibial cartilage metrics from coronal MR image data: Technique, test-retest reproducibility, and findings in osteoarthritis.
Glaser, C; Burgkart, R; Kutschera, A; Englmeier, KH; Reiser, M; Eckstein, F;
MAGNET RESON MED. 2003; 50(6): 1229-1236.
Full papers/articles (Journal)
Validation of cartilage volume and thickness measurements in the human shoulder with quantitative magnetic resonance imaging.
Graichen, H; Jakob, J; von Eisenhart-Rothe, R; Englmeier, KH; Reiser, M; Eckstein, F;
Osteoarthritis Cartilage. 2003; 11(7):475-482
Full papers/articles (Journal)
Influence of adducting and abducting muscle forces on the subacromial space width
Hinterwimmer, S; Von Eisenhart-Rothe, R; Siebert, M; Putz, R; Eckstein, F; Vogl, T; Graichen, H
MED SCI SPORT EXER. 2003; 35(12): 2055-2059.
Full papers/articles (Journal)
Correlation of knee-joint cartilage morphology with muscle cross-sectional areas vs. anthropometric variables
Hudelmaier, M; Glaser, C; Englmeier, KH; Reiser, M; Putz, R; Eckstein, F
ANAT REC PART A. 2003; 270A(2): 175-184.
Full papers/articles (Journal)
Inhomogeneous cartilage properties enhance superficial interstitial fluid support and frictional properties, but do not provide a homogeneous state of stress.
Krishnan, R; Park, S; Eckstein, F; Ateshian, GA;
J Biomech Eng. 2003; 125(5):569-577
Full papers/articles (Journal)
Impact of bone density on distal radius fracture patterns and comparison between five different fracture classifications.
Lill, CA; Goldhahn, J; Albrecht, A; Eckstein, F; Gatzka, C; Schneider, E;
J Orthop Trauma. 2003; 17(4):271-278
Full papers/articles (Journal)
Can novel clinical densitometric techniques replace or improve DXA in predicting bone strength in osteoporosis at the hip and other skeletal sites?
Lochmüller, EM; Müller, R; Kuhn, V; Lill, CA; Eckstein, F;
J Bone Miner Res. 2003; 18(5):906-912
Full papers/articles (Journal)
Precision and accuracy of peripheral quantitative computed tomography (pQCT) in the mouse skeleton compared with histology and microcomputed tomography (microCT).
Schmidt, C; Priemel, M; Kohler, T; Weusten, A; Müller, R; Amling, M; Eckstein, F;
J Bone Miner Res. 2003; 18(8):148-196
Full papers/articles (Journal)
Trabecular bone tissue strains in the healthy and osteoporotic human femur.
Van Rietbergen, B; Huiskes, R; Eckstein, F; Rüegsegger, P;
J Bone Miner Res. 2003; 18(10):1781-1788
Full papers/articles (Journal)
Longitudinal analysis of cartilage atrophy in the knees of patients with spinal cord injury.
Vanwanseele, B; Eckstein, F; Knecht, H; Spaepen, A; Stüssi, E;
Arthritis Rheum. 2003; 48(12):3377-3381
Full papers/articles (Journal)
Book chapters
Skelett- und Muskelsystem; Untere Extremitaet.
Drenckhahn, C; Eckstein, F;
In: Drenckhahn, D (Ed.) editors(s). Benninghoff, Anatomie, Band 1.. p. 341-411.
Form-Funktions-Analyse des Gelenkknorpels mit quantitativer Magnetresonanztomographie (qMRT).
Eckstein, F;
In: Drenckhahn, D (Ed.) editors(s). Schriftenreihe der Deutschen Vereinigung fuer Sportwissenschaft..
2002
Journal Articles
Quantitative cartilage imaging of the human hind foot: precision and inter-subject variability.
Al-Ali, D; Graichen, H; Faber, S; Englmeier, KH; Reiser, M; Eckstein, F;
J Orthop Res. 2002; 20(2): 249-256.
Full papers/articles (Journal)
[Quantitative cartilage analysis with magnetic resonance tomography (qMRI)--a new era in arthrosis diagnosis?].
Eckstein, F; Englmeier, KH; Reiser, M;
Z Rheumatol. 2002; 61(3): 250-259.
Reviews
Functional adaptation of human joints to mechanical stimuli.
Eckstein, F; Faber, S; Mühlbauer, R; Hohe, J; Englmeier, KH; Reiser, M; Putz, R;
Osteoarthritis Cartilage. 2002; 10(1): 44-50.
Full papers/articles (Journal)
Long-term and resegmentation precision of quantitative cartilage MR imaging (qMRI).
Eckstein, F; Heudorfer, L; Faber, SC; Burgkart, R; Englmeier, KH; Reiser, M;
Osteoarthritis Cartilage. 2002; 10(12): 922-928.
Full papers/articles (Journal)
Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.
Eckstein, F; Lochmüller, EM; Koller, B; Wehr, U; Weusten, A; Rambeck, W; Hoeflich, A; Wolf, E;
Growth Horm IGF Res. 2002; 12(2): 116-125.
Full papers/articles (Journal)
Bone strength at clinically relevant sites displays substantial heterogeneity and is best predicted from site-specific bone densitometry.
Eckstein, F; Lochmüller, EM; Lill, CA; Kuhn, V; Schneider, E; Delling, G; Müller, R;
J Bone Miner Res. 2002; 17(1): 162-171.
Full papers/articles (Journal)
Side differences of knee joint cartilage volume, thickness, and surface area, and correlation with lower limb dominance--an MRI-based study.
Eckstein, F; Müller, S; Faber, SC; Englmeier, KH; Reiser, M; Putz, R;
Osteoarthritis Cartilage. 2002; 10(12): 914-921.
Full papers/articles (Journal)
Insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression negatively regulates bone size and mass, but not density, in the absence and presence of growth hormone/IGF-I excess in transgenic mice.
Eckstein, F; Pavicic, T; Nedbal, S; Schmidt, C; Wehr, U; Rambeck, W; Wolf, E; Hoeflich, A;
Anat Embryol (Berl). 2002; 206(1-2): 139-148.
Full papers/articles (Journal)
Quantitative image analysis of the cartilage in Virtual Reality.
Englmeier, KH; Siebert, M; Stammberger, T; von Eisenhardt-Rothe, R; Graichen, H; Eckstein, F; Reiser, M;
Stud Health Technol Inform. 2002; 85: 141-143.
Full papers/articles (Journal)
Surface size, curvature analysis, and assessment of knee joint incongruity with MRI in vivo.
Hohe, J; Ateshian, G; Reiser, M; Englmeier, KH; Eckstein, F;
Magn Reson Med. 2002; 47(3): 554-561.
Full papers/articles (Journal)
Three-dimensional analysis and visualization of regional MR signal intensity distribution of articular cartilage.
Hohe, J; Faber, S; Muehlbauer, R; Reiser, M; Englmeier, KH; Eckstein, F;
Med Eng Phys. 2002; 24(3): 219-227.
Full papers/articles (Journal)
Mechanical strength of the thoracolumbar spine in the elderly: prediction from in situ dual-energy X-ray absorptiometry, quantitative computed tomography (QCT), upper and lower limb peripheral QCT, and quantitative ultrasound.
Lochmüller, EM; Bürklein, D; Kuhn, V; Glaser, C; Müller, R; Glüer, CC; Eckstein, F;
Bone. 2002; 31(1): 77-84.
Full papers/articles (Journal)
Biomechanische Tests in der Evaluation osteodensitometrischer Verfahren-Hintergurnd, Übersicht und aktuelle Befunde.
Lochmüller, EM; Eckstein, F
Osteologie. 2002; 11: 154-177.
Full papers/articles (Journal)
Mechanical strength of the proximal femur as predicted from geometric and densitometric bone properties at the lower limb versus the distal radius.
Lochmüller, EM; Groll, O; Kuhn, V; Eckstein, F;
Bone. 2002; 30(1): 207-216.
Full papers/articles (Journal)
Radius bone strength in bending, compression, and falling and its correlation with clinical densitometry at multiple sites.
Lochmüller, EM; Lill, CA; Kuhn, V; Schneider, E; Eckstein, F;
J Bone Miner Res. 2002; 17(9): 1629-1638.
Full papers/articles (Journal)
Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images.
Pistoia, W; van Rietbergen, B; Lochmüller, EM; Lill, CA; Eckstein, F; Rüegsegger, P;
Bone. 2002; 30(6): 842-848.
Full papers/articles (Journal)
Knee cartilage of spinal cord-injured patients displays progressive thinning in the absence of normal joint loading and movement.
Vanwanseele, B; Eckstein, F; Knecht, H; Stüssi, E; Spaepen, A;
Arthritis Rheum. 2002; 46(8): 2073-2078.
Full papers/articles (Journal)
2001
Journal Articles
Mechanische Festigkeit des distalen Radius unter Biegung und axialem Druck-Korrelation mit der peripheren quantitativen Computertomographie.
Bachmeier M, Eckstein F, Kuhn V, Groll O, Lill C A, Lochmüller E-M
Osteologie. 2001; 10: 193-203.
Full papers/articles (Journal)
Magnetic resonance imaging-based assessment of cartilage loss in severe osteoarthritis: accuracy, precision, and diagnostic value.
Burgkart, R; Glaser, C; Hyhlik-Dürr, A; Englmeier, KH; Reiser, M; Eckstein, F;
Arthritis Rheum. 2001; 44(9): 2072-2077.
Full papers/articles (Journal)
Correlation of thoracic and lumbar vertebral failure loads with in situ vs. ex situ dual energy X-ray absorptiometry.
Bürklein, D; Lochmüller, E; Kuhn, V; Grimm, J; Barkmann, R; Müller, R; Eckstein, F;
J Biomech. 2001; 34(5): 579-587.
Full papers/articles (Journal)
In vivo morphometry and functional analysis of human articular cartilage with quantitative magnetic resonance imaging--from image to data, from data to theory.
Eckstein, F; Reiser, M; Englmeier, KH; Putz, R;
Anat Embryol (Berl). 2001; 203(3): 147-173.
Reviews
Interindividual variability and correlation among morphological parameters of knee joint cartilage plates: analysis with three-dimensional MR imaging.
Eckstein, F; Winzheimer, M; Hohe, J; Englmeier, KH; Reiser, M;
Osteoarthritis Cartilage. 2001; 9(2): 101-111.
Full papers/articles (Journal)
Gender differences in knee joint cartilage thickness, volume and articular surface areas: assessment with quantitative three-dimensional MR imaging.
Faber, SC; Eckstein, F; Lukasz, S; Mühlbauer, R; Hohe, J; Englmeier, KH; Reiser, M;
Skeletal Radiol. 2001; 30(3): 144-150.
Full papers/articles (Journal)
Optimization and validation of a rapid high-resolution T1-w 3D FLASH water excitation MRI sequence for the quantitative assessment of articular cartilage volume and thickness.
Glaser, C; Faber, S; Eckstein, F; Fischer, H; Springer, V; Heudorfer, L; Stammberger, T; Englmeier, KH; Reiser, M;
Magn Reson Imaging. 2001; 19(2): 177-185.
Full papers/articles (Journal)
Sex-specific differences of subacromial space width during abduction, with and without muscular activity, and correlation with anthropometric variables.
Graichen, H; Bonél, H; Stammberger, T; Englmeier, KH; Reiser, M; Eckstein, F;
J Shoulder Elbow Surg. 2001; 10(2): 129-135.
Full papers/articles (Journal)
[Effect of muscle activity on the 3-dimensional movement pattern of the shoulder. Study with open MRI].
Graichen, H; Bonél, H; Stammberger, T; Englmeier, KH; Reiser, M; Eckstein, F;
Unfallchirurg. 2001; 104(4): 288-293.
Full papers/articles (Journal)
An in vivo technique for determining 3D muscular moment arms in different joint positions and during muscular activation - application to the supraspinatus.
Graichen, H; Englmeier, KH; Reiser, M; Eckstein, F;
Clin Biomech (Bristol, Avon). 2001; 16(5): 389-394.
Full papers/articles (Journal)
Three-dimensional analysis of shoulder girdle and supraspinatus motion patterns in patients with impingement syndrome.
Graichen, H; Stammberger, T; Bonél, H; Wiedemann, E; Englmeier, KH; Reiser, M; Eckstein, F;
J Orthop Res. 2001; 19(6): 1192-1198.
Full papers/articles (Journal)
Age-related changes in the morphology and deformational behavior of knee joint cartilage.
Hudelmaier, M; Glaser, C; Hohe, J; Englmeier, KH; Reiser, M; Putz, R; Eckstein, F;
Arthritis Rheum. 2001; 44(11): 2556-2561.
Full papers/articles (Journal)
Precision of high-resolution dual energy X-ray absorptiometry of bone mineral status and body composition in small animal models.
Lochmüller, EM; Jung, V; Weusten, A; Wehr, U; Wolf, E; Eckstein, F;
Eur Cell Mater. 2001; 1: 43-51.
Full papers/articles (Journal)
Effect of fixation, soft-tissues, and scan projection on bone mineral measurements with dual energy X-ray absorptiometry (DXA).
Lochmüller, EM; Krefting, N; Bürklein, D; Eckstein, F;
Calcif Tissue Int. 2001; 68(3): 140-145.
Full papers/articles (Journal)
Prediction of distal radius failure with microFE models based on 3d-PQCT scans.
Pistoia, W; Van Rietbergen, B; Eckstein, F; Lill, C; Lochmüller, EM; Rüegsegger, P;
Adv Exp Med Biol. 2001; 496: 143-151.
Full papers/articles (Journal)
2000
Journal Articles
[A new in vivo technique for 3-dimensional analysis of the translation of femoral condyles and the menisci responding to antagonistic muscle forces].
Bringmann, C; Eckstein, F; Bonél, H; Englmeier, KH; Reiser, M; Graichen, H;
Biomed Tech (Berl). 2000; 45(10): 258-264.
Full papers/articles (Journal)
Analyse der femoralen Knocheneigenschaften MT-bGH transgener Mäuse mit der hochauflösenden pQCT.
Cindik E, Willnecker J, Wolf E, Eckstein F
Osteologie. 2000; 9: 85-93.
Full papers/articles (Journal)
Quantitative determination of articular pressure in the human shoulder joint.
Conzen, A; Eckstein, F;
J Shoulder Elbow Surg. 2000; 9(3): 196-204.
Full papers/articles (Journal)
Patellar cartilage deformation in vivo after static versus dynamic loading.
Eckstein, F; Lemberger, B; Stammberger, T; Englmeier, KH; Reiser, M;
J Biomech. 2000; 33(7): 819-825.
Full papers/articles (Journal)
Effects of joint incongruity on articular pressure distribution and subchondral bone remodeling.
Eckstein, F; Merz, B; Jacobs, CR;
Adv Anat Embryol Cell Biol. 2000; 152: -ix.
Full papers/articles (Journal)
Effect of gradient and section orientation on quantitative analysis of knee joint cartilage.
Eckstein, F; Stammberger, T; Priebsch, J; Englmeier, KH; Reiser, M;
J Magn Reson Imaging. 2000; 11(2): 161-167.
Full papers/articles (Journal)
Effect of gradient and section orientation on quantitative analysis of knee joint cartilage
Eckstein, F; Stammberger, T; Priebsch, J; Englmeier, KH; Reiser, M;
J Magn Reson Imaging. 2000; 11(4): 469-470.
Full papers/articles (Journal)
Validation of high-resolution water-excitation magnetic resonance imaging for quantitative assessment of thin cartilage layers.
Graichen, H; Springer, V; Flaman, T; Stammberger, T; Glaser, C; Englmeier, KH; Reiser, M; Eckstein, F;
Osteoarthritis Cartilage. 2000; 8(2): 106-114.
Full papers/articles (Journal)
Magnetic resonance-based motion analysis of the shoulder during elevation.
Graichen, H; Stammberger, T; Bonel, H; Haubner, M; Englmeier, KH; Reiser, M; Eckstein, F;
Clin Orthop Relat Res. 2000; (370): 154-163.
Full papers/articles (Journal)
Glenohumeral translation during active and passive elevation of the shoulder - a 3D open-MRI study.
Graichen, H; Stammberger, T; Bonel, H; Karl-Hans Englmeier, ; Reiser, M; Eckstein, F;
J Biomech. 2000; 33(5): 609-613.
Full papers/articles (Journal)
[Precision MRI-based joint surface and cartilage density analysis of the knee joint using rapid water-excitation sequence and semi-automatic segmentation algorithm].
Heudorfer, L; Hohe, J; Faber, S; Englmeier, KH; Reiser, M; Eckstein, F;
Biomed Tech (Berl). 2000; 45(11): 304-310.
Full papers/articles (Journal)
A technique for 3D in vivo quantification of proton density and magnetization transfer coefficients of knee joint cartilage.
Hohe, J; Faber, S; Stammberger, T; Reiser, M; Englmeier, KH; Eckstein, F;
Osteoarthritis Cartilage. 2000; 8(6): 426-433.
Full papers/articles (Journal)
Precision of tibial cartilage morphometry with a coronal water-excitation MR sequence.
Hyhlik-Dürr, A; Faber, S; Burgkart, R; Stammberger, T; Maag, KP; Englmeier, KH; Reiser, M; Eckstein, F;
Eur Radiol. 2000; 10(2): 297-303.
Full papers/articles (Journal)
In situ femoral dual-energy X-ray absorptiometry related to ash weight, bone size and density, and its relationship with mechanical failure loads of the proximal femur.
Lochmüller, EM; Miller, P; Bürklein, D; Wehr, U; Rambeck, W; Eckstein, F;
Osteoporos Int. 2000; 11(4): 361-367.
Full papers/articles (Journal)
Comparison of knee joint cartilage thickness in triathletes and physically inactive volunteers based on magnetic resonance imaging and three-dimensional analysis.
Mühlbauer, R; Lukasz, TS; Faber, TS; Stammberger, T; Eckstein, F;
Am J Sports Med. 2000; 28(4): 541-546.
Full papers/articles (Journal)
Elastic registration of 3D cartilage surfaces from MR image data for detecting local changes in cartilage thickness.
Stammberger, T; Hohe, J; Englmeier, KH; Reiser, M; Eckstein, F;
Magn Reson Med. 2000; 44(4): 592-601.
Full papers/articles (Journal)
[MRI-based 3-D analysis of the glenohumeral translation in patients with shoulder instability].
von Eisenhart-Rothe, R; Wiedemann, E; Bonel, H; Eckstein, F; Reiser, M; Englmeier, KH; Graichen, H;
Z Orthop Ihre Grenzgeb. 2000; 138(6): 481-486.
Full papers/articles (Journal)
Monographs ( scientific books)
Volumen und Dicke des Gelenkknorpels-Quantitative Analyse mit der MRT
In: Das patellofemorale Schmerzsyndrom
Glaser, C; Burkart, R; Englmeier, KH; Reiser, M; Eckstein, F
Hrsg: CJ Wirth, M Rudert; Darmstadt: Steinkopf; 2000. pp. 39-50.
Anatomische und biomechanische Aspekte des Gelenkknorpels
In: Knieinstabilität-Knorpelschaden.
Glaser, C; Burkart, R; Englmeier, KH; Reiser, M; Eckstein, F
Darmstadt : Steinkopf; 2000. pp. 12-20.
1999
Journal Articles
Spaltlinienmuster des subchondralen Knochens in Gelenken des menschlichen Fußes und der Hand.
Dietmair S, Putz R, Eckstein F
Osteologie. 1999; 8: 13-22.
Full papers/articles (Journal)
Tension and bending, but not compression alone determine the functional adaptation of subchondral bone in incongruous joints.
Eckstein, F; Merz, B; Schön, M; Jacobs, CR; Putz, R;
Anat Embryol (Berl). 1999; 199(1): 85-97.
Full papers/articles (Journal)
Functional analysis of articular cartilage deformation, recovery, and fluid flow following dynamic exercise in vivo.
Eckstein, F; Tieschky, M; Faber, S; Englmeier, KH; Reiser, M;
Anat Embryol (Berl). 1999; 200(4): 419-424.
Full papers/articles (Journal)
Möglichkeiten der offenen MRT für die biomechanische Analyse und funktionelle Diagnostik des Schultergelenks.
Graichen H, Bonel H, Stammberger T, Englmeier K-H, Reiser M, Eckstein F
Sport-Orthopädie Sport-Traumatologie. 1999; 15: 37-43.
Full papers/articles (Journal)
Subacromial space width changes during abduction and rotation--a 3-D MR imaging study.
Graichen, H; Bonel, H; Stammberger, T; Englmeier, KH; Reiser, M; Eckstein, F;
Surg Radiol Anat. 1999; 21(1): 59-64.
Full papers/articles (Journal)
Three-dimensional analysis of the width of the subacromial space in healthy subjects and patients with impingement syndrome.
Graichen, H; Bonel, H; Stammberger, T; Haubner, M; Rohrer, H; Englmeier, KH; Reiser, M; Eckstein, F;
AJR Am J Roentgenol. 1999; 172(4): 1081-1086.
Full papers/articles (Journal)
[An MR-based technique for determination of the subacromial space width in subjects with and without shoulder muscle activity].
Graichen, H; Bonel, H; Stammberger, T; Heuck, A; Englmeier, KH; Reiser, M; Eckstein, F;
Z Orthop Ihre Grenzgeb. 1999; 137(1): 2-6.
Full papers/articles (Journal)
A non-destructive technique for 3-D microstructural phenotypic characterisation of bones in genetically altered mice: preliminary data in growth hormone transgenic animals and normal controls.
Graichen, H; Lochmüller, EM; Wolf, E; Langkabel, B; Stammberger, T; Haubner, M; Renner-Müller, I; Englmeier, KH; Eckstein, F;
Anat Embryol (Berl). 1999; 199(3): 239-248.
Full papers/articles (Journal)
Precision and intersite correlation of bone densitometry at the radius, tibia and femur with peripheral quantitative CT.
Groll, O; Lochmüller, EM; Bachmeier, M; Willnecker, J; Eckstein, F;
Skeletal Radiol. 1999; 28(12): 696-702.
Full papers/articles (Journal)
In situ measurement of articular cartilage deformation in intact femoropatellar joints under static loading.
Herberhold, C; Faber, S; Stammberger, T; Steinlechner, M; Putz, R; Englmeier, KH; Reiser, M; Eckstein, F;
J Biomech. 1999; 32(12): 1287-1295.
Full papers/articles (Journal)
MR-basierte Quantifizierung des Knorpelverlustes bei Gonarthrose.
Hyhlik-Dürr, A; Burgkart, R; Glaser, C; Englmeier, KH; Reiser, M; Eckstein, F
Sport-Orthopädie Sport-Traumatologie. 1999; 15: 44-46.
Full papers/articles (Journal)
Comparison of quantitative ultrasound in the human calcaneus with mechanical failure loads of the hip and spine.
Lochmüller, EM; Eckstein, F; Zeller, JB; Steldinger, R; Putz, R;
Ultrasound Obstet Gynecol. 1999; 14(2): 125-133.
Full papers/articles (Journal)
[Sex-specific analysis of bone mass in normal and growth hormone transgenic mice using dual energy x-ray absorptiometry (DXA)].
Lochmüller, EM; Weusten, A; Wolf, E; Cindik, E; Renner-Müller, I; Eikmeier, T; Eckstein, F;
Ann Anat. 1999; 181(2): 191-198.
Full papers/articles (Journal)
Determination of calcaneal ultrasound properties ex situ: reproducibility, effects of storage, formalin fixation, maceration, and changes in anatomic measurement site.
Pöpperl, G; Lochmüller, E; Becker, H; Mall, G; Steinlechner, M; Eckstein, F;
Calcif Tissue Int. 1999; 65(3): 192-197.
Full papers/articles (Journal)
Determination of 3D cartilage thickness data from MR imaging: computational method and reproducibility in the living.
Stammberger, T; Eckstein, F; Englmeier, KH; Reiser, M;
Magn Reson Med. 1999; 41(3): 529-536.
Full papers/articles (Journal)
Interobserver reproducibility of quantitative cartilage measurements: comparison of B-spline snakes and manual segmentation.
Stammberger, T; Eckstein, F; Michaelis, M; Englmeier, KH; Reiser, M;
Magn Reson Imaging. 1999; 17(7): 1033-1042.
Full papers/articles (Journal)
[Preferential direction of collagen fibrils in the sub-chondral bone bone and the hip and shoulder joint].
Vogt, S; Eckstein, F; Schön, M; Putz, R;
Ann Anat. 1999; 181(2):181-189
Full papers/articles (Journal)
Quantitative determination of joint incongruity and pressure distribution during simulated gait and cartilage thickness in the human hip joint.
von Eisenhart, R; Adam, C; Steinlechner, M; Müller-Gerbl, M; Eckstein, F;
J Orthop Res. 1999; 17(4): 532-539.
Full papers/articles (Journal)
[Quantitative determination of pressure distribution in the hip joint during the gait cycle].
von Eisenhart-Rothe, R; Witte, H; Steinlechner, M; Müller-Gerbl, M; Putz, R; Eckstein, F;
Unfallchirurg. 1999; 102(8): 625-631.
Full papers/articles (Journal)
Seitenvergleich und interindividuelle Variabilitdt der akromiohumeralen Distanzmessung in der offenen 3D Magnetresonanztomographie.
Zewen, S; Graichen, H; Bonel, H; Stammberger, T; Englmeier, KH; Reiser, M; Eckstein, F
Osteologie. 1999; 8: 218-227.
Full papers/articles (Journal)
Newspaper/magazine articles
Knorpel als komplexe Knautschzone-neue Wege der quantitativen Analyse mit der Magnetresonanztomographie (MRT).
Eckstein, F; Reiser, M; Englmeier, KH; Putz, R
Einsichten: Forschung an der Ludwig-Maximilians-Universität München. 1999. 1/99: 10-13.
1998
Journal Articles
The distribution of cartilage thickness within the joints of the lower limb of elderly individuals.
Adam, C; Eckstein, F; Milz, S; Putz, R;
J Anat. 1998; 193 ( Pt 2): 203-214.
Full papers/articles (Journal)
The distribution of cartilage thickness in the knee-joints of old-aged individuals -- measurement by A-mode ultrasound.
Adam, C; Eckstein, F; Milz, S; Schulte, E; Becker, C; Putz, R;
Clin Biomech (Bristol, Avon). 1998; 13(1): 1-10.
Full papers/articles (Journal)
Thickness of the subchondral mineralised tissue zone (SMZ) in normal male and female and pathological human patellae.
Eckstein, F; Milz, S; Anetzberger, H; Putz, R;
J Anat. 1998; 192 ( Pt 1): 81-90.
Full papers/articles (Journal)
Accuracy of cartilage volume and thickness measurements with magnetic resonance imaging.
Eckstein, F; Schnier, M; Haubner, M; Priebsch, J; Glaser, C; Englmeier, KH; Reiser, M;
Clin Orthop Relat Res. 1998; 352: 137-148.
Full papers/articles (Journal)
Effect of physical exercise on cartilage volume and thickness in vivo: MR imaging study.
Eckstein, F; Tieschky, M; Faber, SC; Haubner, M; Kolem, H; Englmeier, KH; Reiser, M;
Radiology. 1998; 207(1): 243-248.
Full papers/articles (Journal)
In vivo reproducibility of three-dimensional cartilage volume and thickness measurements with MR imaging.
Eckstein, F; Westhoff, J; Sittek, H; Maag, KP; Haubner, M; Faber, S; Englmeier, KH; Reiser, M;
AJR Am J Roentgenol. 1998; 170(3): 593-597.
Full papers/articles (Journal)
Quantitative relationships of normal cartilage volumes of the human knee joint--assessment by magnetic resonance imaging.
Eckstein, F; Winzheimer, M; Westhoff, J; Schnier, M; Haubner, M; Englmeier, KH; Reiser, M; Putz, R;
Anat Embryol (Berl). 1998; 197(5): 383-390.
Full papers/articles (Journal)
A technique for determining the spatial relationship between the rotator cuff and the subacromial space in arm abduction using MRI and 3D image processing.
Graichen, H; Bonel, H; Stammberger, T; Heuck, A; Englmeier, KH; Reiser, M; Eckstein, F;
Magn Reson Med. 1998; 40(4): 640-643.
Full papers/articles (Journal)
An MR-based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint.
Herberhold, C; Stammberger, T; Faber, S; Putz, R; Englmeier, KH; Reiser, M; Eckstein, F;
Magn Reson Med. 1998; 39(5): 843-850.
Full papers/articles (Journal)
Prediction of vertebral failure loads from spinal and femoral dual-energy X-ray absorptiometry, and calcaneal ultrasound: an in situ analysis with intact soft tissues.
Lochmüller, EM; Eckstein, F; Kaiser, D; Zeller, JB; Landgraf, J; Putz, R; Steldinger, R;
Bone. 1998; 23(5): 417-424.
Full papers/articles (Journal)
Correlation of femoral and lumbar DXA and calcaneal ultrasound, measured in situ with intact soft tissues, with the in vitro failure loads of the proximal femur.
Lochmüller, EM; Zeller, JB; Kaiser, D; Eckstein, F; Landgraf, J; Putz, R; Steldinger, R;
Osteoporos Int. 1998; 8(6): 591-598.
Full papers/articles (Journal)
[Sex-specific analysis of cartilage volume in the knee joint--a quantitative MRI-based study].
Lukasz, S; Mühlbauer, R; Faber, S; Englmeier, KH; Reiser, M; Eckstein, F;
Ann Anat. 1998; 180(6): 487-493.
Full papers/articles (Journal)
Knorpelvolumina im Kniegelenk von Sportlern und Nicht-Sportlern-eine quantitative Analyse mittels Magnetresonanztomographie.
Mühlbauer R, Lukasz S, Faber S, Englmeier K- H, Reiser M, Eckstein F
Sport-Orthopädie Sport-Traumatologie. 1998; 14: 117-121.
Full papers/articles (Journal)
[Relevance of susceptibility-induced geometrical distortion for validity of MRI-based cartilage volume and density measurements of the knee joint].
Schnier, M; Priebsch, J; Faber, S; Haubner, M; Glaser, C; Englmeier, KH; Reiser, M; Eckstein, F;
Biomed Tech (Berl). 1998; 43(9): 243-248.
Full papers/articles (Journal)
Subchondrale Spaltlinien des menschlichen Ellbogen- und Kniegelenks-Ausdruck der Biegung und Zugbeanspruchung des subchondralen Knochens ?
Schön, M; Eckstein, F; Vogt, S; Huber, W; Putz, R
Osteologie. 1998; 7: 77-87.
Full papers/articles (Journal)
[Noninvasive analysis of cartilage volume and cartilage thickness in the human elbow joint using MRI].
Springer, V; Graichen, H; Stammberger, T; Englmeier, KH; Reiser, M; Eckstein, F;
Ann Anat. 1998; 180(4): 331-338.
Full papers/articles (Journal)
A method for quantifying time dependent changes in MR signal intensity of articular cartilage as a function of tissue deformation in intact joints.
Stammberger, T; Herberhold, C; Faber, S; Englmeier, KH; Reiser, M; Eckstein, F;
Med Eng Phys. 1998; 20(10): 741-749.
Full papers/articles (Journal)
Wertigkeit femoraler und lumbaler Knochendichtemessungen für die Beurteilung der femoralen Bruchlast-eine In-situ-Analyse mittels DXA bei intaktem Weichteilmantel.
Zeller, JB; Lochmüller, EM; Kaiser, D; Eckstein, F; Landgraf, J; Steldinger, R; Putz, R;
Osteologie. 1998; 7: 37-47.
Full papers/articles (Journal)
Monographs ( scientific books)
Anatomische und biomechanische Aspekte des Gelenkknorpels
Eckstein, F; Reiser, M; Englmeier, KH; Putz, R
Darmstadt: Steinkopf; 1998. pp. 12-20.
Newspaper/magazine articles
Cartilage morphology, function, and degeneration-new quantitative approaches with 3-D MR imaging.
Eckstein, F; Graichen, H; Bonel, H; Englmeier, KH; Reiser, M
Medical Imaging International . 1998. 8: 10-19.
Messung von Knorpelvolumen- und -dicken des Kniegelenks mit der MRT.
Medizin im Bild 5:7-10 (1998)
Eckstein, F; Graichen, H; Bonel, H; Englmeier, KH; Reiser, M
Medizin im Bild. 1998. 5: 7-10.
1997
Journal Articles
Non-invasive determination of cartilage thickness throughout joint surfaces using magnetic resonance imaging.
Eckstein, F; Adam, C; Sittek, H; Becker, C; Milz, S; Schulte, E; Reiser, M; Putz, R;
J Biomech. 1997; 30(3):285-289
Full papers/articles (Journal)
Aktuelle Aspekte der funktionellen Anpassung und der mechanisch bedingten Degeneration des Gelenkknorpels: neue Perspektiven durch die MagnetresonanztomographieTeil II) Lösungswege mittels eines nichtinvasiven bildgebenden Verfahrens.
Eckstein, F; Faber, S; Lösch, A; Sittek, H; Haubner, M; Schnier, M; Fischer, H; Englmeier, KH; Reiser, M
Sport-Orthopädie Sport-Traumatologie. 1997; 13: 28-36.
Full papers/articles (Journal)
Mechanobiological adaptation of subchondral bone as a function of joint incongruity and loading.
Eckstein, F; Jacobs, CR; Merz, BR;
Med Eng Phys. 1997; 19(8): 720-728.
Full papers/articles (Journal)
Quantitative analysis of incongruity, contact areas and cartilage thickness in the human hip joint.
Eckstein, F; von Eisenhart-Rothe, R; Landgraf, J; Adam, C; Loehe, F; Müller-Gerbl, M; Putz, R;
Acta Anat (Basel). 1997; 158(3): 192-204.
Full papers/articles (Journal)
Hybrid rendering of multidimensional image data.
Englmeier, KH; Haubner, M; Lösch, A; Eckstein, F; Seemann, MD; van Eimeren, W; Reiser, M;
Methods Inf Med. 1997; 36(1): 1-10.
Full papers/articles (Journal)
A non-invasive technique for 3-dimensional assessment of articular cartilage thickness based on MRI. Part 2: Validation using CT arthrography.
Haubner, M; Eckstein, F; Schnier, M; Lösch, A; Sittek, H; Becker, C; Kolem, H; Reiser, M; Englmeier, KH;
Magn Reson Imaging. 1997; 15(7): 805-813.
Full papers/articles (Journal)
Computer simulation of subchondral bone adaptation to mechanical loading in an incongruous joint.
Jacobs, CR; Eckstein, F;
Anat Rec. 1997; 249(3): 317-326.
Full papers/articles (Journal)
A non-invasive technique for 3-dimensional assessment of articular cartilage thickness based on MRI. Part 1: Development of a computational method.
Lösch, A; Eckstein, F; Haubner, M; Englmeier, KH;
Magn Reson Imaging. 1997; 15(7): 795-804.
Full papers/articles (Journal)
Mechanical implications of humero-ulnar incongruity--finite element analysis and experiment.
Merz, B; Eckstein, F; Hillebrand, S; Putz, R;
J Biomech. 1997; 30(7): 713-721.
Full papers/articles (Journal)
Thickness distribution of the subchondral mineralization zone of the trochlear notch and its correlation with the cartilage thickness: an expression of functional adaptation to mechanical stress acting on the humeroulnar joint?
Milz, S; Eckstein, F; Putz, R;
Anat Rec. 1997; 248(2): 18-97.
Full papers/articles (Journal)
[Three-dimensional thickness and volume measurements of the knee joint cartilage using MRI: validation in an anatomical specimen by CT arthrography].
Schnier, M; Eckstein, F; Priebsch, J; Haubner, M; Sittek, H; Becker, C; Putz, R; Englmeier, KH; Reiser, M;
Rofo. 1997; 167(5): 521-526.
Full papers/articles (Journal)
Repeatability of patellar cartilage thickness patterns in the living, using a fat-suppressed magnetic resonance imaging sequence with short acquisition time and three-dimensional data processing.
Tieschky, M; Faber, S; Haubner, M; Kolem, H; Schulte, E; Englmeier, KH; Reiser, M; Eckstein, F;
J Orthop Res. 1997; 15(6): 808-813.
Full papers/articles (Journal)
Quantitative Bestimmung von patellaren Knorpelvolumen- und Knorpeldickenänderungen nach dynamischer mechanischer Belastung mittels 3D MR-Chondro-Crassometrie.
Tieschky, M;Eckstein, F; Lösch, A; Faber, S; Haubner, M; Kolem, H; Englmeier, KH; Putz, R; Reiser, M
Sport-Orthopädie Sport-Traumatologie. 1997; 13: 118-122.
Full papers/articles (Journal)
Direct comparison of contact areas, contact stress and subchondral mineralization in human hip joint specimens.
von Eisenhart-Rothe, R; Eckstein, F; Müller-Gerbl, M; Landgraf, J; Rock, C; Putz, R;
Anat Embryol (Berl). 1997; 195(3): 279-288.
Full papers/articles (Journal)
[Three-dimensional thickness and volume measurements of the knee joint cartilage by MR tomography: reproducibility in volunteers].
Westhoff, J; Eckstein, F; Sittek, H; Lösch, A; Faber, S; Kolem, H; Englmeier, KH; Reiser, M;
Rofo. 1997; 167(6): 585-590.
Full papers/articles (Journal)
A calculation of the forces acting on the human acetabulum during walking. Based On in vivo force measurements, kinematic analysis and morphometry.
Witte, H; Eckstein, F; Recknagel, S;
Acta Anat (Basel). 1997; 160(4): 269-280.
Full papers/articles (Journal)
[Effective forces during walking on the human hip acetabulum].
Witte, H; Eckstein, F; Recknagel, S; Bernsmann, K;
Biomed Tech (Berl). 1997; 42 Suppl: 428-429.
Letters
1996
Journal Articles
Schnittanatomie des Schultergelenks (Teil 1)
Burgkart, R; Merl, T; Weinhart, H; Eckstein, F; Schittich, I; Gerhardt, P
Sport-Orthopädie Sport-Traumatologie. 1996; 12: 222-226.
Full papers/articles (Journal)
Schnittanatomie des Schultergelenks (Teil 2)
Burgkart, R; Merl, T; Weinhart, H; Eckstein, F; Schittich, I; Gerhardt, P
Sport-Orthopädie Sport-Traumatologie. 1996; 12: 295-299.
Full papers/articles (Journal)
Determination of knee joint cartilage thickness using three-dimensional magnetic resonance chondro-crassometry (3D MR-CCM).
Eckstein, F; Gavazzeni, A; Sittek, H; Haubner, M; Lösch, A; Milz, S; Englmeier, KH; Schulte, E; Putz, R; Reiser, M;
Magn Reson Med. 1996; 36(2): 256-265.
Full papers/articles (Journal)
Aktuelle Aspekte zu Aufbau, funktioneller Anpassung und der mechanisch bedingten Degeneration des Gelenkknorpels: Neue Perspektiven durch die Magnetresonanztomographie Teil I) Stand der Forschung und ungelöste Probleme.
Eckstein, F; Glaser, C; Burgkart, R; Putz, R
Sport-Orthopädie Sport-Traumatologie. 1996; 12: 197-206.
Full papers/articles (Journal)
Magnetic resonance chondro-crassometry (MR CCM): a method for accurate determination of articular cartilage thickness?
Eckstein, F; Sittek, H; Gavazzeni, A; Schulte, E; Milz, S; Kiefer, B; Reiser, M; Putz, R;
Magn Reson Med. 1996; 35(1): 89-96.
Full papers/articles (Journal)
Structure, strain and function of the transverse acetabular ligament.
Löhe, F; Eckstein, F; Sauer, T; Putz, R;
Acta Anat (Basel). 1996; 157(4): 315-323.
Full papers/articles (Journal)
Computer-aided three dimensional assessment of knee-joint cartilage with magnetic resonance imaging.
Muensterer, OJ; Eckstein, F; Hahn, D; Putz, R;
Clin Biomech (Bristol, Avon). 1996; 11(5): 260-266.
Full papers/articles (Journal)
Assessment of normal patellar cartilage volume and thickness using MRI: an analysis of currently available pulse sequences.
Sittek, H; Eckstein, F; Gavazzeni, A; Milz, S; Kiefer, B; Schulte, E; Reiser, M;
Skeletal Radiol. 1996; 25(1): 55-62.
Full papers/articles (Journal)
1995
Journal Articles
Schnittanatomie des Kniegelenks
Burgkart, R; Schelter, R; Eckstein, F; Sittek, H; Schittich, I; Träger, J
Sport-Orthopädie Sport-Traumatologie. 1995; 11: 188-192.
Full papers/articles (Journal)
Morphomechanics of the humero-ulnar joint: I. Joint space width and contact areas as a function of load and flexion angle.
Eckstein, F; Löhe, F; Hillebrand, S; Bergmann, M; Schulte, E; Milz, S; Putz, R;
Anat Rec. 1995; 243(3): 318-326.
Full papers/articles (Journal)
Morphomechanics of the humero-ulnar joint: II. Concave incongruity determines the distribution of load and subchondral mineralization.
Eckstein, F; Merz, B; Müller-Gerbl, M; Holzknecht, N; Pleier, M; Putz, R;
Anat Rec. 1995; 243(3): 327-335.
Full papers/articles (Journal)
Subchondral bone density in the human elbow assessed by computed tomography osteoabsorptiometry: a reflection of the loading history of the joint surfaces.
Eckstein, F; Müller-Gerbl, M; Steinlechner, M; Kierse, R; Putz, R;
J Orthop Res. 1995; 13(2): 268-278.
Full papers/articles (Journal)
[Knee joint cartilage in magnetic resonance tomography. MR chondrovolumetry (MR-CVM) using fat-suppressed FLASH 3D sequence].
Eckstein, F; Sittek, H; Gavazzeni, A; Milz, S; Kiefer, B; Putz, R; Reiser, M;
Radiologe. 1995; 35(2): 87-93.
Full papers/articles (Journal)
The potential of magnetic resonance imaging (MRI) for quantifying articular cartilage thickness -- a methodological study.
Eckstein, F; Sittek, H; Milz, S; Schulte, E; Kiefer, B; Reiser, M; Putz, R;
Clin Biomech (Bristol, Avon). 1995; 10(8): 434-440.
Full papers/articles (Journal)
Die Bestimmung der quantitativen Verteilung des hyalinen Knorpelgewebes mittels Magnetresonanztomographie Welches ist die geeignetste Sequenz?
Gavazzeni A, Eckstein F, Sittek H, Milz S, Schulte E, Kiefer B, Putz R, Reiser M
Sport-Orthopädie Sport-Traumatologie. 1995; 11: 176-182.
Full papers/articles (Journal)
3D MR-Chondro-Crassometrie-eine Methode zur nicht-invasiven, automatisierten, dreidimensionalen Bestimmung der Knorpeldicke mittels Magnetresonanztomographie.
Lösch A, Eckstein F, Haubner M, Sittek H, Gavazzeni A, Milz S, Kolem H, Kiefer B, Reiser M, Englmeier K
Sport-Orthopädie Sport-Traumatologie. 1995; 11: 183-186.
Full papers/articles (Journal)
The thickness of the subchondral plate and its correlation with the thickness of the uncalcified articular cartilage in the human patella.
Milz, S; Eckstein, F; Putz, R;
Anat Embryol (Berl). 1995; 192(5): 437-444.
Full papers/articles (Journal)
[Magnetic resonance tomography in trauma of the knee joint].
Sittek, H; Heuck, A; Eckstein, F; Reiser, M;
Radiologe. 1995; 35(2): 101-108.
Reviews
1994
Journal Articles
Stress distribution in the trochlear notch. A model of bicentric load transmission through joints.
Eckstein, F; Löhe, F; Müller-Gerbl, M; Steinlechner, M; Putz, R;
J Bone Joint Surg Br. 1994; 76(4): 647-653.
Full papers/articles (Journal)
The influence of geometry on the stress distribution in joints--a finite element analysis.
Eckstein, F; Merz, B; Schmid, P; Putz, R;
Anat Embryol (Berl). 1994; 189(6): 54-52.
Full papers/articles (Journal)
[The distribution of cartilage degeneration of the human patella in relation to individual subchondral mineralization].
Eckstein, F; Müller-Gerbl, M; Putz, R;
Z Orthop Ihre Grenzgeb. 1994; 132(5): 405-411.
Full papers/articles (Journal)
The morphology of articular cartilage assessed by magnetic resonance imaging (MRI). Reproducibility and anatomical correlation.
Eckstein, F; Sittek, H; Milz, S; Putz, R; Reiser, M;
Surg Radiol Anat. 1994; 16(4): 429-438.
Full papers/articles (Journal)
[Stress on the ligamentum transversum acetabuli in physiological stress on the hip joint].
Löhe, F; Eckstein, F; Putz, R;
Unfallchirurg. 1994; 97(9): 445-449.
Full papers/articles (Journal)
1993
Journal Articles
Physiological incongruity of the humero-ulnar joint: a functional principle of optimized stress distribution acting upon articulating surfaces?
Eckstein, F; Löhe, F; Schulte, E; Müller-Gerbl, M; Milz, S; Putz, R;
Anat Embryol (Berl). 1993; 188(5): 449-455.
Full papers/articles (Journal)
[Areas of contact in human humero-ulnar joints as a function of pressure, their connection through subchondral mineralization and joint surface morphology of the incisura trochlearis].
Eckstein, F; Löhe, F; Steinlechner, M; Müller-Gerbl, M; Putz, R;
Ann Anat. 1993; 175(6): 545-552.
Full papers/articles (Journal)
Cartilage degeneration in the human patellae and its relationship to the mineralisation of the underlying bone: a key to the understanding of chondromalacia patellae and femoropatellar arthrosis?
Eckstein, F; Putz, R; Müller-Gerbl, M; Steinlechner, M; Benedetto, KP;
Surg Radiol Anat. 1993; 15(4): 279-286.
Full papers/articles (Journal)
[Mechanical stress and subchondral mineralization of the human elbow joint. A CT-osteoabsorptiometric study].
Eckstein, F; Steinlechner, M; Müller-Gerbl, M; Putz, R;
Unfallchirurg. 1993; 96(8): 399-404.
Full papers/articles (Journal)
1992
Journal Articles
Distribution of subchondral bone density and cartilage thickness in the human patella.
Eckstein, F; Müller-Gerbl, M; Putz, R;
J Anat. 1992; 180 ( Pt 3): 425-433.
Full papers/articles (Journal)