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Forschungsdatenbank PMU-SQQUID

AKRAM MUHAMMAD
Universitätsinstitut für Pharmazie

Publikationen

20 Publikationen

2019

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Identification of the fungicide epoxiconazole as inhibitor of human 11ß-hydroxylase and aldosterone synthase.
Akram, M; Patt, M; Kaserer, T; Temml, V; Waratchareeyakul, W; Kratschmar, DV; Haupenthal, J; Hartmann, RW; Odermatt, A; Schuster, D;
10. Paracelsus Science Get Together Abstractband 2019.. 2019; -10. Paracelsus Science Get Together; 28.06.2019; Nürnberg.
Abstracts (Zeitschrift)
Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11ß-hydroxylase and aldosterone synthase
Akram, M; Patt, M; Kaserer, T; Temml, V; Waratchareeyakul, W; Kratschmar, DV; Haupenthal, J; Hartmann, RW; Odermatt, A; Schuster, D;
Final Programme & Book of Abstracts. 2019; -26th Scientific Congress of the Austrian Pharmaceutical Society ; 25.-27.04.2019; Graz.
Abstracts (Zeitschrift)

2018

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

The anti-fungal epoxiconazole inhibits human CYP P450 11B1 and CYP P450 11B2: Virtual screening as a tool to find potential endocrine disruptors.
Akram, M; Patt, M; Kaserer, T; Temml, V; Waratchareeyakul, W; Haupenthal, J; Hartmann, RW; Odermatt, A; Schuster, D;
Paracelsus Science Get Together Abstractband 2018.. 2018; 31-31.-Paracelsus Science Get Together 2018; 29.6.2018; Paracelsus Medizinische Privatuniversität Salzburg. (ISBN: 978-3-200-05737-1 )
Abstracts (Zeitschrift)
Development and validation of pharmacophore models for human cytochrome P450 11 B1 and P450 11B2 inhibition.
Waratchareeyakul, W; Akram, M; Haupenthal, J; Hartmann, RW; Schuster, D;
Paracelsus Science Get Together Abstractband 2018.. 2018; 163-163.-Paracelsus Science Get Together 2018; 29.6.2018; Paracelsus Medizinische Privatuniverstität Salzburg. (ISBN: 978-3-200-05737-1 )
Abstracts (Zeitschrift)

2017

Beiträge in Fachzeitschriften

Pharmacophore Modeling and in Silico/in Vitro Screening for Human Cytochrome P450 11B1 and Cytochrome P450 11B2 Inhibitors
Akram, M; Waratchareeyakul, W; Haupenthal, J; Hartmann, RW; Schuster, D
FRONT CHEM. 2017; 5: 104
Originalarbeiten (Zeitschrift)
Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole.
Beck, KR; Bachler, M; Vuorinen, A; Wagner, S; Akram, M; Griesser, U; Temml, V; Klusonova, P; Yamaguchi, H; Schuster, D; Odermatt, A
BIOCHEM PHARMACOL. 2017; 130: 93-103.
Originalarbeiten (Zeitschrift)
A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature.
Hochleitner, J; Akram, M; Ueberall, M; Davis, RA; Waltenberger, B; Stuppner, H; Sturm, S; Ueberall, F; Gostner, JM; Schuster, D
SCI REP-UK. 2017; 7(1): 8071
Originalarbeiten (Zeitschrift)
Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.
Vuorinen, A; Engeli, RT; Leugger, S; Bachmann, F; Akram, M; Atanasov, AG; Waltenberger, B; Temml, V; Stuppner, H; Krenn, L; Ateba, SB; Njamen, D; Davis, RA; Odermatt, A; Schuster, D
J Nat Prod. 2017; 80(4):965-974
Originalarbeiten (Zeitschrift)

Nichtpublizierte (nicht zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

The anti-fungal epoxiconazole inhibits CYP P450 11B1 and CYP P450 11B2: Virtual screening as a tool to find potential endocrine disruptors.
Akram, M; Patt, M; Kaserer, T; Temml, V; Watchareeyakul, W; Haupenthal, J; Hartmann, RW; Odermatt, A; Schuster, D;
Life Science PhD Meeting Innsbruck 2017; 18.-19.04.2017; Innsbruck. 2017.
Three dimensional pharmacophore modeling and model validation of human CYP11B1 and CYP11B2 inhibition, potential targets for treating Cushing's syndrome and congestive heart failure.
Akram, M; Waratchareeyakul, W; Kaserer, T; Haupenthal, J; Hartmann, RW; Schuster, D;
PHARMA 2030 – CURRENT AND FUTURE CHALLENGES; 20.–22.04.2017; University of Innsbruck. 2017.
Docking of azole fungicides into human 11β-HSD1, 11β-HSD2 and murine 11β-HSD2.
Wagner, S; Beck, KR; Bächler, M; Vuorinen, A; Akram, M; Griesser, U; Temml, V; Klusonova, P; Yamaguchi, H; Odermatt, A; Schuster, D;
PHARMA 2030 – current and future challanges; 20.–22.04.2017; University of Innsbruck. 2017.

2016

Nichtpublizierte (nicht zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Pharmacophore-based virtual screening for identification of novel inhibitors of CYP17.
Akram, M; Schuster, D;
6th CMBI annual Meeting; 03.-04.03.2016; Innsbruck. 2016.
Natural products as a rich source for potential anti-osteoporotic lead agents inhibiting 17β-hydroxysteroid dehydrogenase type 2.
Vuorinen, A; Engeli, RT; Leugger, S; Bachmann, F; Akram, M; Atanasov, AG; Waltenberger, B; Temml, V; Stuppner, H; Krenn, L; Ateba, S.B; Njamen, D; Davis, R; Odermatt, A; Schuster, D;
Swiss Society of Pharmacology and Toxicology Spring Meeting; 21.04.2016; Bern. 2016.

2015

Beiträge in Fachzeitschriften

Pharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid Dehydrogenases.
Kaserer, T; Beck, KR; Akram, M; Odermatt, A; Schuster, D
Molecules. 2015; 20(12):22799-22832
Übersichtsarbeiten

Nichtpublizierte (nicht zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Pharmacophore Modeling and virtual screening to discover cytochrome P450 17 inhibitors among environmental chemicals.
Akram, M; Schuster, D;
29th Molecular Modeling Workshop; 09.-11.03.2015; Erlangen. 2015.
Molecular modeling of cytochrome P450 17 inhibitors for predicting the toxic effects of environmental chemicals.
Akram, M; Schuster, D;
MCBO Science Day & 7th Life Science Day; 27.02.2015; Innsbruck. 2015.
Pharmacophore model-based identification of environmental chemicals inhibiting hydroxysteroid dehydrogenases.
Schuster, D; Vuorinen, A; Engeli, R; Akram, M; Beck, K; Kaserer,T; Odermatt, A;
3rd Congress on Steroid Research; 15.-18.11.2015; Chicago, Illinois . 2015.

2014

Nichtpublizierte (nicht zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Discovery of butein as a natural 17β-hydroxysteroid dehydrogenase type 2 inhibitor by ligand-based pharmacophore modeling.
Akram, M; Vuorinen, A; Bachmann, F; Meyer, A; Odermatt, A; Schuster, D;
International Symposium: Natural Products and Drug Discovery - Future Perspectives; 13.-14.11.2014; Wien. 2014.
Molecular modeling of 11β-hydroxysteroid dehydrogenase type 2 inhibition, glucocorticoid antagonism, and mineralcorticoid agonism for predicting chronic toxic effects of phytochemicals.
Akram, M; Vuorinen, A; Rollinger, JM; Schuster, D;
28th Molecular Modeling Workshop; 17.-19.3.2014; Erlangen. 2014.
Hydroxysteroid dehydrogenase inhibitors as potential endocrine disrupting agents.
Akram, M; Vuorinen, A; Schuster, D;
6th Life Science Meeting; 24.-25.09.2014; Innsbruck. 2014.