Coexistence of Two Distinct Tumor Types Within One Posterior Fossa Mass Lesion in an Adult Patient Verified by DNA-Methylation Analysis: A Case Report.
Rezai, A; Pöppe, JP; Spendel, M; Kraus, TFJ; Stevanovic, V; Griessenauer, CJ; Schwartz, C;
Cureus. 2023; 15(2):e35111
Fallberichte

Fatal course of undetected Ewing-like sarcoma in a 9-year-old boy with uncharacteristic clinical presentation.
Gotsmy, W; Neumayer, B; Kraus, T; Zellinger, B; Neureiter, D; Monticelli, F; Meyer, H; Hofer, P;
Forensic Sci Med Pathol. 2022; 18(3):231-239
Fallberichte

EGFR Amplification Is a Phenomenon of IDH Wildtype and TERT Mutated High-Grade Glioma: An Integrated Analysis Using Fluorescence In Situ Hybridization and DNA Methylome Profiling.
Hölzl, D; Hutarew, G; Zellinger, B; Alinger-Scharinger, B; Schlicker, HU; Schwartz, C; Sotlar, K; Kraus, TFJ;
Biomedicines. 2022; 10(4):
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Methylome Profiling of PD-L1-Expressing Glioblastomas Shows Enrichment of Post-Transcriptional and RNA-Associated Gene Regulation.
Hutarew, G; Hölzl, D; Schiefer, T; Langwieder, CK; Alinger-Scharinger, B; Schlicker, HU; Schwartz, C; Sotlar, K; Kraus, TFJ;
Cancers (Basel). 2022; 14(21):
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A patient with two gliomas with independent oligodendroglioma and glioblastoma biology proved by DNA-methylation profiling: a case report and review of the literature.
Kraus, TFJ; Schwartz, C; Machegger, L; Zellinger, B; Hölzl, D; Schlicker, HU; Pöppe, J; Ladisich, B; Spendel, M; Kral, M; Sotlar, K;
Brain Tumor Pathol. 2022; 39(2): 111-119.
Fallberichte

A new player in the game: treatment with antagomiR-21a-5p significantly attenuates histological and echocardiographic effects of experimental autoimmune myocarditis.
Mirna, M; Paar, V; Topf, A; Kraus, T; Sotlar, PK; Aigner, PA; Ewe, DRNA; Watzinger, S; Podesser, PBK; Hackl, M; Pistulli, R; Hoppe, PUC; Kiss, A; Lichtenauer, APM;
Cardiovasc Res. 2022; 118(2):556-572
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Meningeal metastasis causing chronic subdural hematoma in a cancer patient with bilateral papilledema and suspected cerebral venous thrombosis - A case report.
Pangratz-Daller, C; Grimm, J; Pfaff, JAR; Kraus, TFJ; Sotlar, K; Al-Schameri, AR; Kral, M; Griessenauer, CJ; Schwartz, C;
J Neurol Surg A Cent Eur Neurosurg. 2022;
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On the Acceptance of "Fake" Histopathology: A Study on Frozen Sections Optimized with Deep Learning.
Siller, M; Stangassinger, LM; Kreutzer, C; Boor, P; Bulow, RD; Kraus, TJF; von Stillfried, S; Wolfl, S; Couillard-Despres, S; Oostingh, GJ; Hittmair, A; Gadermayr, M;
J Pathol Inform. 2022; 13: 6
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Integrated analysis of programmed cell death ligand 1 expression reveals increased levels in high-grade glioma.
Hölzl, D; Hutarew, G; Zellinger, B; Schlicker, HU; Schwartz, C; Winkler, PA; Sotlar, K; Kraus, TFJ;
J Cancer Res Clin Oncol. 2021; 147(8):2271-2280
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Genotypical glioblastoma of the frontal lobe mimicking ganglioglioma: A case report and review of the literature.
Kraus, TFJ; Pöppe, J; Machegger, L; Zellinger, B; Dovjak, E; Schlicker, HU; Schwartz, C; Ladisich, B; Spendel, M; Al-Schameri, AR; Winkler, PA; Sotlar, K;
Clin Case Rep. 2021; 9(9): e04544
Fallberichte

Diffuse midline glioma of the cervical spinal cord with H3 K27M genotype phenotypically mimicking anaplastic ganglioglioma: a case report and review of the literature.
Kraus, TFJ; Machegger, L; Pöppe, J; Zellinger, B; Dovjak, E; Schlicker, HU; Schwartz, C; Ladisich, B; Spendel, M; Kral, M; Reinhardt, A; Winkler, PA; Sotlar, K;
Brain Tumor Pathol. 2020; 37(3): 89-94.
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Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction.
Wernly, B; Paar, V; Aigner, A; Pilz, PM; Podesser, BK; Förster, M; Jung, C; Hofbauer, JP; Tockner, B; Wimmer, M; Kraus, T; Motloch, LJ; Hackl, M; Hoppe, UC; Kiss, A; Lichtenauer, M;
Cells. 2020; 9(2):
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Autoimmune myocarditis is not associated with left ventricular systolic dysfunction.
Mirna, M; Paar, V; Kraus, T; Sotlar, K; Wernly, B; Pistulli, R; Hoppe, UC; Lichtenauer, M;
Eur J Clin Invest. 2019; 49(8): e13132
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Murine Experimental Autoimmune Myocarditis (EAM) is associated with LV hypertrophy but not with reduced LV systolic function
Mirna, MM; Paar, V; Kraus, T; Sotlar, K; Wernly, B; Pistulli, R; Lichtenauer, M
EUR J HEART FAIL. 2019; 21: 473-473.
Abstracts (Zeitschrift)

TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas.
Biczok, A; Kraus, T; Suchorska, B; Terpolilli, NA; Thorsteinsdottir, J; Giese, A; Tonn, JC; Schichor, C
J NEURO-ONCOL. 2018; 139(3): 671-678.
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Cell Type and Species-specific Patterns in Neuronal and Non-neuronal Methylomes of Human and Chimpanzee Cortices.
Böck, J; Remmele, CW; Dittrich, M; Müller, T; Kondova, I; Persengiev, S; Bontrop, RE; Ade, CP; Kraus, TFJ; Giese, A; El Hajj, N; Schneider, E; Haaf, T;
Cereb Cortex. 2018; 28(10): 3724-3739.
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DNA methylation analysis on purified neurons and glia dissects age and Alzheimers disease-specific changes in the human cortex.
Gasparoni, G; Bultmann, S; Lutsik, P; Kraus, TFJ; Sordon, S; Vlcek, J; Dietinger, V; Steinmaurer, M; Haider, M; Mulholland, CB; Arzberger, T; Roeber, S; Riemenschneider, M; Kretzschmar, HA; Giese, A; Leonhardt, H; Walter, J;
Epigenetics Chromatin. 2018; 11(1): 41
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Emergence of exosomal DNA in molecular neuropathology
Kraus, TFJ
LABORATORIUMSMEDIZIN. 2018; 42(1-2): 9-22.
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Altered Long Noncoding RNA Expression Precedes the Course of Parkinsons Disease-a Preliminary Report.
Kraus, TFJ; Haider, M; Spanner, J; Steinmaurer, M; Dietinger, V; Kretzschmar, HA;
Mol Neurobiol. 2017; 54(4): 2869-2877.
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Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms.
Schmitt, A; Martins-de-Souza, D; Akbarian, S; Cassoli, JS; Ehrenreich, H; Fischer, A; Fonteh, A; Gattaz, WF; Gawlik, M; Gerlach, M; Grünblatt, E; Halene, T; Hasan, A; Hashimoto, K; Kim, YK; Kirchner, SK; Kornhuber, J; Kraus, TFJ; Malchow, B; Nascimento, JM; Rossner, M; Schwarz, M; Steiner, J; Talib, L; Thibaut, F; Riederer, P; Falkai, P;
World J Biol Psychiatry. 2017; 18(5): 330-356.
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Epigenetic dysregulation in the developing Down syndrome cortex.
El Hajj, N; Dittrich, M; Böck, J; Kraus, TF; Nanda, I; Müller, T; Seidmann, L; Tralau, T; Galetzka, D; Schneider, E; Haaf, T;
Epigenetics. 2016; 11(8): 563-578.
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Decreased Oligodendrocyte and Neuron Number in Anterior Hippocampal Areas and the Entire Hippocampus in Schizophrenia: A Stereological Postmortem Study.
Falkai, P; Malchow, B; Wetzestein, K; Nowastowski, V; Bernstein, HG; Steiner, J; Schneider-Axmann, T; Kraus, T; Hasan, A; Bogerts, B; Schmitz, C; Schmitt, A;
Schizophr Bull. 2016; 42 Suppl 1: S4-S12.
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Oligodendrocyte and Interneuron Density in Hippocampal Subfields in Schizophrenia and Association of Oligodendrocyte Number with Cognitive Deficits.
Falkai, P; Steiner, J; Malchow, B; Shariati, J; Knaus, A; Bernstein, HG; Schneider-Axmann, T; Kraus, T; Hasan, A; Bogerts, B; Schmitt, A;
Front Cell Neurosci. 2016; 10:78
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Profiling of methylation and demethylation pathways during brain development and ageing.
Kraus, TF; Kilinc, S; Steinmaurer, M; Stieglitz, M; Guibourt, V; Kretzschmar, HA;
J Neural Transm (Vienna). 2016; 123(3):189-203
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Quantifying prion disease penetrance using large population control cohorts.
Minikel, EV; Vallabh, SM; Lek, M; Estrada, K; Samocha, KE; Sathirapongsasuti, JF; McLean, CY; Tung, JY; Yu, LP; Gambetti, P; Blevins, J; Zhang, S; Cohen, Y; Chen, W; Yamada, M; Hamaguchi, T; Sanjo, N; Mizusawa, H; Nakamura, Y; Kitamoto, T; Collins, SJ; Boyd, A; Will, RG; Knight, R; Ponto, C; Zerr, I; Kraus, TF; Eigenbrod, S; Giese, A; Calero, M; de Pedro-Cuesta, J; Haïk, S; Laplanche, JL; Bouaziz-Amar, E; Brandel, JP; Capellari, S; Parchi, P; Poleggi, A; Ladogana, A; ODonnell-Luria, AH; Karczewski, KJ; Marshall, JL; Boehnke, M; Laakso, M; Mohlke, KL; Kähler, A; Chambert, K; McCarroll, S; Sullivan, PF; Hultman, CM; Purcell, SM; Sklar, P; van der Lee, SJ; Rozemuller, A; Jansen, C; Hofman, A; Kraaij, R; van Rooij, JG; Ikram, MA; Uitterlinden, AG; van Duijn, CM; Daly, MJ; MacArthur, DG;
Sci Transl Med. 2016; 8(322):322ra9
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[Sporadic Cerebral Amyloid Angiopathy: An Overview with Clinical Cases].
Schöberl, F; Eren, OE; Wollenweber, FA; Kraus, T; Kellert, L;
Fortschr Neurol Psychiatr. 2016; 84(9):53-41
Übersichtsarbeiten

Parkinsons disease: SNCA-, PARK2-, and LRRK2- targeting microRNAs elevated in cingulate gyrus.
Tatura, R; Kraus, T; Giese, A; Arzberger, T; Buchholz, M; Höglinger, G; Müller, U;
Parkinsonism Relat Disord. 2016; 33:115-121
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DNA methylation levels of α-synuclein intron 1 in the aging brain.
de Boni, L; Riedel, L; Schmitt, I; Kraus, TFJ; Kaut, O; Piston, D; Akbarian, S; Wüllner, U;
Neurobiol Aging. 2015; 36(12):3334.e7-3334.e11
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Long non-coding RNA normalisers in human brain tissue.
Kraus, TF; Greiner, A; Guibourt, V; Kretzschmar, HA;
J Neural Transm (Vienna). 2015; 122(7):10-54
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Identification of Stably Expressed lncRNAs as Valid Endogenous Controls for Profiling of Human Glioma.
Kraus, TF; Greiner, A; Guibourt, V; Lisec, K; Kretzschmar, HA;
J Cancer. 2015; 6(2):111-119
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Genetic Characterization of Ten-Eleven-Translocation Methylcytosine Dioxygenase Alterations in Human Glioma.
Kraus, TF; Greiner, A; Steinmaurer, M; Dietinger, V; Guibourt, V; Kretzschmar, HA;
J Cancer. 2015; 6(9):83-42
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5-Hydroxymethylcytosine, the "Sixth Base", during brain development and ageing.
Kraus, TF; Guibourt, V; Kretzschmar, HA;
J Neural Transm (Vienna). 2015; 122(7):1035-1043
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Loss of 5-hydroxymethylcytosine and intratumoral heterogeneity as an epigenomic hallmark of glioblastoma.
Kraus, TF; Kolck, G; Greiner, A; Schierl, K; Guibourt, V; Kretzschmar, HA;
Tumour Biol. 2015; 36(11):8439-8446
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Long-term outcome of patients with WHO Grade III and IV gliomas treated by fractionated intracavitary radioimmunotherapy.
Reulen, HJ; Poepperl, G; Goetz, C; Gildehaus, FJ; Schmidt, M; Tatsch, K; Pietsch, T; Kraus, T; Rachinger, W;
J Neurosurg. 2015; 123(3):76-70
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Age-dependent levels of 5-methyl-, 5-hydroxymethyl-, and 5-formylcytosine in human and mouse brain tissues.
Wagner, M; Steinbacher, J; Kraus, TF; Michalakis, S; Hackner, B; Pfaffeneder, T; Perera, A; Müller, M; Giese, A; Kretzschmar, HA; Carell, T;
Angew Chem Int Ed Engl. 2015; 54(42):12511-12514
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Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization.
Dieterich, LC; Mellberg, S; Langenkamp, E; Zhang, L; Zieba, A; Salomäki, H; Teichert, M; Huang, H; Edqvist, PH; Kraus, T; Augustin, HG; Olofsson, T; Larsson, E; Söderberg, O; Molema, G; Pontén, F; Georgii-Hemming, P; Alafuzoff, I; Dimberg, A;
J Pathol. 2012; 228(3):378-390
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Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors.
Kraus, TF; Globisch, D; Wagner, M; Eigenbrod, S; Widmann, D; Münzel, M; Müller, M; Pfaffeneder, T; Hackner, B; Feiden, W; Schüller, U; Carell, T; Kretzschmar, HA;
Int J Cancer. 2012; 131(7):1577-1590
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Evolutionarily conserved herpesviral protein interaction networks.
Fossum, E; Friedel, CC; Rajagopala, SV; Titz, B; Baiker, A; Schmidt, T; Kraus, T; Stellberger, T; Rutenberg, C; Suthram, S; Bandyopadhyay, S; Rose, D; von Brunn, A; Uhlmann, M; Zeretzke, C; Dong, YA; Boulet, H; Koegl, M; Bailer, SM; Koszinowski, U; Ideker, T; Uetz, P; Zimmer, R; Haas, J;
PLoS Pathog. 2009; 5(9):e1000570
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