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Forschungsdatenbank PMU-SQQUID

ABLINGER MICHAEL
Universitätsklinik für Dermatologie
Forschungsprogramm für Molekulare Therapie bei Genodermatosen

Publikationen

25 Publikationen

2022

Beiträge in Fachzeitschriften

5'RNA Trans-Splicing Repair of COL7A1 Mutant Transcripts in Epidermolysis Bullosa
Mayr, E; Ablinger, M; Lettner, T; Murauer, EM; Guttmann-Gruber, C; Piñón Hofbauer, J; Hainzl, S; Kaiser, M; Klausegger, A; Bauer, JW; Koller, U; Wally, V;
Int J Mol Sci. 2022; 23(3):
Originalarbeiten (Zeitschrift)
Transcriptome-Guided Drug Repurposing for Aggressive SCCs.
Zauner, R; Wimmer, M; Dorfer, S; Ablinger, M; Koller, U; Piñón Hofbauer, J; Guttmann-Gruber, C; Bauer, JW; Wally, V;
Int J Mol Sci. 2022; 23(2):
Originalarbeiten (Zeitschrift)

2021

Beiträge in Fachzeitschriften

Personalized Development of Antisense Oligonucleotides for Exon Skipping Restores Type XVII Collagen Expression in Junctional Epidermolysis Bullosa.
Ablinger, M; Lettner, T; Friedl, N; Potocki, H; Palmetzhofer, T; Koller, U; Illmer, J; Liemberger, B; Hainzl, S; Klausegger, A; Reisenberger, M; Lambert, J; Van Gele, M; Desmet, E; Van Maelsaeke, E; Wimmer, M; Zauner, R; Bauer, JW; Wally, V;
Int J Mol Sci. 2021; 22(7):
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Development of a non-invasive and non-viral in vivo RNA therapy approach for dystrophic epidermolysis bullosa
Liemberger, B; Kocher, T; Lettner, T; Ablinger, M; Reichl, V; Lackner, N; Peking, P; Murauer, EM; Nystrom, A; Wally, V; Mayr, E; Guttmann-Gruber, C; Bauer, JW; Koller, U
EXP DERMATOL. 2021; 30(3): E43-E43.
Abstracts (Zeitschrift)

Beiträge in Sonstigen Zeitschriften

Erforschung von miRNAs bei aggressiven Plattenepithelkarzinomen
Ablinger, M; Wally, V; Zauner, R; Wimmer, M;
Spectrum Dermatologie. 2021.

2020

Beiträge in Fachzeitschriften

A cancer stem cell-like phenotype is associated with miR-10b expression in aggressive squamous cell carcinomas.
Wimmer, M; Zauner, R; Ablinger, M; Piñón-Hofbauer, J; Guttmann-Gruber, C; Reisenberger, M; Lettner, T; Niklas, N; Proell, J; Sajinovic, M; De Souza, P; Hainzl, S; Kocher, T; Murauer, EM; Bauer, JW; Strunk, D; Reichelt, J; Mellick, AS; Wally, V;
Cell Commun Signal. 2020; 18(1): 61
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

MIRNA-10B MARKS AGGRESSIVE SQUAMOUS CELL CARCINOMAS IN RDEB
Wimmer, M; Zauner, R; Ablinger, M; Pinon-Hofbauer, J; Guttmann-Gruber, C; Reisenberger, M; Lettner, T; Niklas, N; Proell, J; Sajinovic, M; De Souza, P; Hainzl, S; Murauer, EM; Bauer, JW; Strunk, D; Reichelt, J; Mellick, AS; Wally, V
ACTA DERM-VENEREOL. 2020; 100: 35-36.
Abstracts (Zeitschrift)
CIRCULATING CELL-FREE MIRNA SCREENING FOR RDEB-SCC BIOMARKER IDENTIFICATION
Zauner, R; Wimmer, M; Ablinger, M; Lettner, T; Atzmuller, S; Proll, J; Bauer, JW; Wally, V
ACTA DERM-VENEREOL. 2020; 100: 37-37.
Abstracts (Zeitschrift)

2019

Beiträge in Fachzeitschriften

Gene Editing-Mediated Disruption of Epidermolytic Ichthyosis-Associated KRT10 Alleles Restores Filament Stability in Keratinocytes.
March, OP; Lettner, T; Klausegger, A; Ablinger, M; Kocher, T; Hainzl, S; Peking, P; Lackner, N; Rajan, N; Hofbauer, JP; Guttmann-Gruber, C; Bygum, A; Koller, U; Reichelt, J;
J Invest Dermatol. 2019; 139(8): 1699-1710.e6.
Originalarbeiten (Zeitschrift)
An ex vivo RNA trans-splicing strategy to correct human generalized severe epidermolysis bullosa simplex.
Peking, P; Breitenbach, JS; Ablinger, M; Muss, WH; Poetschke, FJ; Kocher, T; Koller, U; Hainzl, S; Kitzmueller, S; Bauer, JW; Reichelt, J; Lettner, T; Wally, V;
Br J Dermatol. 2019; 180(1):141-148
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Gene editing as a therapeutic option for epidermolytic ichthyosis
March, OP; Lettner, T; Klausegger, A; Ablinger, M; Kocher, T; Hainzl, S; Peking, P; Lackner, N; Aushev, M; Koller, U; Reichelt, J
EXP DERMATOL. 2019; 28(3): E45-E45.
Abstracts (Zeitschrift)
Correction of type XVII collagen using spliceosome-mediated RNA trans-splicing
Reisenberger, M; Schlager, P; Reichelt, J; Bauer, JW; Koller, U; Hainzl, S; Ablinger, M; Lettner, T; Wally, V
EUR J HUM GENET. 2019; 27: 109-110.
Abstracts (Zeitschrift)
Major player in miRNA processing appear altered in recessive dystrophic epidermolysis bullosa squamous cell carcinoma
Wimmer, M; Zauner, R; Waldmann, A; Bodocian, H; Ablinger, M; Atzmueller, S; Proell, J; Strunk, D; Bauer, JW; Reichelt, J; Wally, V
EUR J HUM GENET. 2019; 27: 109-109.
Abstracts (Zeitschrift)

2018

Beiträge in Fachzeitschriften

Basal pharmacokinetic parameters of topically applied diacerein in pediatric patients with generalized severe epidermolysis bullosa simplex.
Ablinger, M; Felder, TK; Wimmer, M; Zauner, R; Hofbauer, P; Lettner, T; Wolkersdorfer, M; Lagler, FB; Diem, A; Bauer, JW; Wally, V;
Orphanet J Rare Dis. 2018; 13(1): 193
Letter
Diacerein orphan drug development for epidermolysis bullosa simplex: A phase 2/3 randomized, placebo-controlled, double-blind clinical trial.
Wally, V; Hovnanian, A; Ly, J; Buckova, H; Brunner, V; Lettner, T; Ablinger, M; Felder, TK; Hofbauer, P; Wolkersdorfer, M; Lagler, FB; Hitzl, W; Laimer, M; Kitzmüller, S; Diem, A; Bauer, JW;
J Am Acad Dermatol. 2018; 78(5): 892-901.e7.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

TALEN-mediated inactivation of dominant-negative keratin alleles for general phenotypic alleviation of epidermolytic ichthyosis
March, OP; Kocher, T; Lackner, N; Hainzl, S; Lettner, T; Ablinger, M; Klausegger, A; Koller, U; Reichelt, J
HUM GENE THER. 2018; 29(12): A114-A114.
Abstracts (Zeitschrift)

2017

Beiträge in Fachzeitschriften

Cut and Paste: Efficient Homology-Directed Repair of a Dominant Negative KRT14 Mutation via CRISPR/Cas9 Nickases.
Kocher, T; Peking, P; Klausegger, A; Murauer, EM; Hofbauer, JP; Wally, V; Lettner, T; Hainzl, S; Ablinger, M; Bauer, JW; Reichelt, J; Koller, U;
Mol Ther. 2017; 25(11):2585-2598
Originalarbeiten (Zeitschrift)
Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy.
Machado, Y; Duinkerken, S; Hoepflinger, V; Mayr, M; Korotchenko, E; Kurtaj, A; Pablos, I; Steiner, M; Stoecklinger, A; Lübbers, J; Schmid, M; Ritter, U; Scheiblhofer, S; Ablinger, M; Wally, V; Hochmann, S; Raninger, AM; Strunk, D; van Kooyk, Y; Thalhamer, J; Weiss, R;
J Control Release. 2017; 266:87-99
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Topically applied diacerein: Basic pharmacokinetics in generalized-severe epidermolysis bullosa simplex
Ablinger, M; Felder, T; Wimmer, M; Zauner, R; Hofbauer, P; Wolkersdorfer, M; Lagler, F; Diem, A; Bauer, JW; Wally, V
J INVEST DERMATOL. 2017; 137(10): S198-S198.
Abstracts (Zeitschrift)
Improved safety profile: An efficient CRISPR/Cas9 double nicking approach for KRT14 repair in EB simplex
Kocher, T; Peking, P; Klausegger, A; Murauer, EM; Hofbauer, JP; Wally, V; Lettner, T; Hainzl, S; Ablinger, M; Bauer, JW; Reichelt, J; Koller, U
J INVEST DERMATOL. 2017; 137(10): S225-S225.
Abstracts (Zeitschrift)
Highly efficient and safe CRISPR/Cas9n double nicking-mediated KRT14 repair in epidermolysis bullosa simplex keratinocytes
Kocher, T; Peking, P; Klausegger, A; Murauer, EM; Hofbauer, JP; Wally, V; Lettner, T; Hainzl, S; Ablinger, M; Bauer, JW; Reichelt, J; Koller, U
HUM GENE THER. 2017; 28(12): A57-A57.
Abstracts (Zeitschrift)
Altering the splice pattern of COL17A1 with antisense oligonucleotides
Potocki, H; Lettner, T; Ablinger, M; Wimmer, M; Zauner, R; Friedl, N; Reichelt, J; Bauer, JW; Wally, V
J INVEST DERMATOL. 2017; 137(10): S227-S227.
Abstracts (Zeitschrift)

2016

Beiträge in Fachzeitschriften

CD4+ T cells, but not non-classical monocytes, are dispensable for the development of chronic lymphocytic leukemia in the TCL1-tg murine model.
Kocher, T; Asslaber, D; Zaborsky, N; Flenady, S; Denk, U; Reinthaler, P; Ablinger, M; Geisberger, R; Bauer, JW; Seiffert, M; Hartmann, TN; Greil, R; Egle, A; Piñón Hofbauer, J;
Leukemia. 2016; 30(6):1409-1413
Letter

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

A murine transplantation model for trans-splicing corrected human keratinocytes
Ablinger, M; Breitenbach, JS; Lettner, T; Muss, W; Peking, P; Hainzl, S; Kocher, T; Kitzmuller, SK; Reichelt, J; Bauer, JW; Wally, V
HUM GENE THER. 2016; 27(11): A184-A184.
Abstracts (Zeitschrift)

2015

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Trans-splicing gene therapy in the KRT14 gene
Breitenbach, JS; Lettner, T; Kocher, T; Muss, W; Peking, P; Hainzl, S; Kitzmuller, SK; Ablinger, M; Potschke, FJ; Bauer, JW; Wally, V
HUM GENE THER. 2015; 26(10): A44-A44.
Abstracts (Zeitschrift)