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Forschungsdatenbank PMU-SQQUID

MURAUER EVA MARIA
Universitätsklinik für Dermatologie
Forschungsprogramm für Molekulare Therapie bei Genodermatosen

Publikationen | Forscherprofil

68 Publikationen

2018

Beiträge in Fachzeitschriften

RNA Trans-Splicing Modulation via Antisense Molecule Interference.
Liemberger, B; Piñón Hofbauer, J; Wally, V; Arzt, C; Hainzl, S; Kocher, T; Murauer, EM; Bauer, JW; Reichelt, J; Koller, U;
Int J Mol Sci. 2018; 19(3):
Originalarbeiten (Zeitschrift)
Functional therapies for cutaneous wound repair in epidermolysis bullosa.
Peking, P; Koller, U; Murauer, EM;
Adv Drug Deliv Rev. 2018; 129:330-343
Originalarbeiten (Zeitschrift)

2017

Beiträge in Fachzeitschriften

Closure of a Large Chronic Wound through Transplantation of Gene-Corrected Epidermal Stem Cells.
Bauer, JW; Koller, J; Murauer, EM; De Rosa, L; Enzo, E; Carulli, S; Bondanza, S; Recchia, A; Muss, W; Diem, A; Mayr, E; Schlager, P; Gratz, IK; Pellegrini, G; De Luca, M;
J Invest Dermatol. 2017; 137(3): 778-781.
Letter
RNA-based therapies for genodermatoses.
Bornert, O; Peking, P; Bremer, J; Koller, U; van den Akker, PC; Aartsma-Rus, A; Pasmooij, AM; Murauer, EM; Nyström, A;
Exp Dermatol. 2017; 26(1):3-10
Übersichtsarbeiten
Targeted RNA-Seq profiling of splicing pattern in the DMD gene: exons are mostly constitutively spliced in human skeletal muscle
Bouge, AL; Murauer, E; Beyne, E; Miro, J; Varilh, J; Taulan, M; Koenig, M; Claustres, M; Tuffery-Giraud, S
SCI REP-UK. 2017; 7: 39094
Originalarbeiten (Zeitschrift)
COL7A1 Editing via CRISPR/Cas9 in Recessive Dystrophic Epidermolysis Bullosa.
Hainzl, S; Peking, P; Kocher, T; Murauer, EM; Larcher, F; Del Rio, M; Duarte, B; Steiner, M; Klausegger, A; Bauer, JW; Reichelt, J; Koller, U;
Mol Ther. 2017; 25(11):2573-2584
Originalarbeiten (Zeitschrift)
Cut and Paste: Efficient Homology-Directed Repair of a Dominant Negative KRT14 Mutation via CRISPR/Cas9 Nickases.
Kocher, T; Peking, P; Klausegger, A; Murauer, EM; Hofbauer, JP; Wally, V; Lettner, T; Hainzl, S; Ablinger, M; Bauer, JW; Reichelt, J; Koller, U;
Mol Ther. 2017; 25(11):2585-2598
Originalarbeiten (Zeitschrift)
An RNA-targeted therapy for dystrophic epidermolysis bullosa.
Peking, P; Koller, U; Duarte, B; Murillas, R; Wolf, S; Maetzig, T; Rothe, M; Kocher, T; García, M; Brachtl, G; Schambach, A; Larcher, F; Reichelt, J; Bauer, JW; Murauer, EM;
Nucleic Acids Res. 2017; 45(17): 1025-10269.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Ex vivo COL7A1 editing via CRISPR/Cas9 in recessive dystrophic epidermolysis bullosa
Hainzl, S; Peking, P; Kocher, T; Murauer, E; Larcher, F; Duarte, B; Steiner, M; Bauer, J; Reichelt, J; Koller, U
J INVEST DERMATOL. 2017; 137(5): S92-S92.
Abstracts (Zeitschrift)
A novel population of skin-tropic T cells with a potential role in wound healing
Klicznik, MM; Duhen, T; Motley, S; Hoellbacher, B; Sir, A; Reitsamer, R; Murauer, EM; Campbell, DJ; Gratz, IK
J INVEST DERMATOL. 2017; 137(10): S244-S244.
Abstracts (Zeitschrift)
Improved safety profile: An efficient CRISPR/Cas9 double nicking approach for KRT14 repair in EB simplex
Kocher, T; Peking, P; Klausegger, A; Murauer, EM; Hofbauer, JP; Wally, V; Lettner, T; Hainzl, S; Ablinger, M; Bauer, JW; Reichelt, J; Koller, U
J INVEST DERMATOL. 2017; 137(10): S225-S225.
Abstracts (Zeitschrift)
Highly efficient and safe CRISPR/Cas9n double nicking-mediated KRT14 repair in epidermolysis bullosa simplex keratinocytes
Kocher, T; Peking, P; Klausegger, A; Murauer, EM; Hofbauer, JP; Wally, V; Lettner, T; Hainzl, S; Ablinger, M; Bauer, JW; Reichelt, J; Koller, U
HUM GENE THER. 2017; 28(12): A57-A57.
Abstracts (Zeitschrift)
Antisense RNA-mediated improvement of SMaRT therapy for KRT14 correction
Liemberger, B; Arzt, C; Hainzl, S; Kocher, T; Hofbauer, JP; Murauer, EM; Bauer, JW; Reichelt, J; Koller, U
J INVEST DERMATOL. 2017; 137(10): S229-S229.
Abstracts (Zeitschrift)
Enhanced genome editing using split Staphylococcus aureus Cas9 delivered in self-complementary AAV vectors
Liemberger, B; Arzt, C; Hainzl, S; Wally, V; Kocher, T; Hofbauer, JP; Murauer, EM; Bauer, JW; Reichelt, J; Koller, U
HUM GENE THER. 2017; 28(12): A63-A63.
Abstracts (Zeitschrift)
RNA trans-splicing-mediated COL7A1 repair in a dystrophic epidermolysis bullosa mouse model
Peking, P; Koller, U; Kocher, T; Nystroem, A; Reichelt, J; Bauer, JW; Murauer, EM
J INVEST DERMATOL. 2017; 137(10): S229-S229.
Abstracts (Zeitschrift)
Transcriptome profiling in recessive dystrophic epidermolysis bullosa patients
Zauner, R; Wimmer, M; Lettner, T; Gruber, C; Murauer, EM; Reichelt, J; Strunk, D; Bauer, JW; Wally, V
J INVEST DERMATOL. 2017; 137(10): S288-S288.
Abstracts (Zeitschrift)

2016

Beiträge in Fachzeitschriften

A knot polymer mediated non-viral gene transfection for skin cells
Cutlar, L; Gao, YS; Aied, A; Greiser, U; Murauer, EM; Zhou, DZ; Wang, WX
BIOMATER SCI-UK. 2016; 4(1): 92-95.
Originalarbeiten (Zeitschrift)
Designing Efficient Double RNA trans-Splicing Molecules for Targeted RNA Repair.
Huttner, C; Murauer, EM; Hainzl, S; Kocher, T; Neumayer, A; Reichelt, J; Bauer, JW; Koller, U
Int J Mol Sci. 2016; 17(10):
Originalarbeiten (Zeitschrift)
A Gene Gun-mediated Nonviral RNA trans-splicing Strategy for Col7a1 Repair.
Peking, P; Koller, U; Hainzl, S; Kitzmueller, S; Kocher, T; Mayr, E; Nyström, A; Lener, T; Reichelt, J; Bauer, JW; Murauer, EM;
Mol Ther Nucleic Acids. 2016; 5: e287
Originalarbeiten (Zeitschrift)
Construction and validation of an RNA trans-splicing molecule suitable to repair a large number of COL7A1 mutations.
Tockner, B; Kocher, T; Hainzl, S; Reichelt, J; Bauer, JW; Koller, U; Murauer, EM;
Gene Ther. 2016; 23(11):775-784
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Regeneration of a functional epidermis at a large, long-standing wound by gene-corrected autologous epidermal stem cells
Bauer, JW; Murauer, EM; Koller, J; De Rosa, L; Enzo, E; Carulli, S; Muss, W; Mayr, E; Pellegrini, G; De Luca, M
J INVEST DERMATOL. 2016; 136(9): S189-S189.
Abstracts (Zeitschrift)
CRISPR/Cas9-mediated gene correction of COL7A1 in dystrophic epidermolysis bullosa
Hainzl, S; Kocher, T; Murauer, EM; Larcher, F; Steiner, M; Bauer, JW; Koller, U
HUM GENE THER. 2016; 27(11): A144-A144.
Abstracts (Zeitschrift)
CRISPR/Cas9-mediated gene repair in the COL7A1 gene
Hainzl, S; Kocher, T; Murauer, EM; Larcher, F; Steiner, M; Bauer, JW; Reichelt, J; Koller, U
J INVEST DERMATOL. 2016; 136(9): S189-S189.
Abstracts (Zeitschrift)
Combining antisense molecules with splicing modulation for KRT14 repair in epidermolysis bullosa
Liemberger, B; Arzt, C; Hainzl, S; Hofbauer, JP; Wally, V; Murauer, EM; Bauer, JW; Reichelt, J; Koller, U
J INVEST DERMATOL. 2016; 136(9): S189-S189.
Abstracts (Zeitschrift)
Antisense RNA-mediated improvement of SMaRT therapy for KRT14 correction
Liemberger, B; Arzt, C; Hainzl, S; Hofbauer, JP; Wally, V; Murauer, EM; Bauer, JW; Reichelt, J; Koller, U
HUM GENE THER. 2016; 27(11): A135-A135.
Abstracts (Zeitschrift)
Long-term in vivo correction of a recessive dystrophic epidermolysis bullosa phenotype using RNA trans-splicing repair
Peking, P; Koller, U; Duarte, BG; Wolf, S; Murrillas, R; Diez, MG; Schambach, A; Larcher, F; Bauer, JW; Murauer, EM
J INVEST DERMATOL. 2016; 136(9): S189-S189.
Abstracts (Zeitschrift)

2015

Beiträge in Fachzeitschriften

Trans-splicing improvement by the combined application of antisense strategies.
Koller, U; Hainzl, S; Kocher, T; Hüttner, C; Klausegger, A; Gruber, C; Mayr, E; Wally, V; Bauer, JW; Murauer, EM;
Int J Mol Sci. 2015; 16(1):117-191
Originalarbeiten (Zeitschrift)
Advances in Gene/Cell Therapy in Epidermolysis Bullosa.
Murauer, EM; Koller, U; Pellegrini, G; De Luca, M; Bauer, JW;
Keio J Med. 2015; 64(2): 21-25.
Übersichtsarbeiten

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

The design and analysis of double RNA trans-splicing molecules for COL7A1 repair
Huttner, C; Hainzl, S; Murauer, EM; Bauer, JW; Koller, U
HUM GENE THER. 2015; 26(10): A48-A48.
Abstracts (Zeitschrift)
The combined application of antisense-based strategies for RNA repair
Huttner, C; Murauer, EM; Hainzl, S; Kocher, T; Bauer, JW; Koller, U
HUM GENE THER. 2015; 26(10): A48-A48.
Abstracts (Zeitschrift)
A fluorescence-based screening system accelerates the design of RNA trans-splicing molecules for mRNA repair.
Kocher, T; Koller, U; Seyr, J; Hainzl, S; Mayer, E; Brachtl, G; Lener, T; Bauer, J; Wally, V; Murauer, E
J INVEST DERMATOL. 2015; 135: S60-S60.
Abstracts (Zeitschrift)
Analysis of binding characteristics of RNA trans-splicing molecules using a fluorescence-based screening system
Koller, U; Kocher, T; Seyr, J; Hainzl, S; Mayr, E; Tockner, B; Brachtl, G; Bauer, JW; Wally, V; Murauer, EM
EXP DERMATOL. 2015; 24(3): E16-E17.
Abstracts (Zeitschrift)
Correction of type VII collagen in a murine recessive dystrophic epidermolysis bullosa model using RNA trans-splicing
Peking, P; Koller, U; Hainzl, S; Kocher, T; Mayr, E; Kitzmuller, S; Lener, T; Bruckner-Tudermann, L; Bauer, JW; Murauer, EM
HUM GENE THER. 2015; 26(10): A48-A48.
Abstracts (Zeitschrift)

2014

Beiträge in Fachzeitschriften

Considerations for a Successful RNA Trans-splicing Repair of Genetic Disorders.
Koller, U; Wally, V; Bauer, JW; Murauer, EM;
Mol Ther Nucleic Acids. 2014; 3: e157
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Internal exon replacement as a promising tool for COL7A1 RNA repair
Huttner, C; Hainzl, S; Murauer, EM; Bauer, JW; Koller, U
J INVEST DERMATOL. 2014; 134: S58-S58.
Abstracts (Zeitschrift)
Selection of antisense oligonucleotides for trans-splicing enhancement using a fluorescence-based screening system
Koller, U; Hainzl, S; Huttner, C; Kocher, T; Klausegger, A; Murauer, EM; Gruber, C; Mayr, E; Wally, V; Bauer, JW
J INVEST DERMATOL. 2014; 134: S61-S61.
Abstracts (Zeitschrift)
Correction of type VII collagen in dystrophic epidermolysis bullosa by novel trans-splicing molecules
Peking, P; Mayr, E; Koller, U; Hainzl, S; Kocher, T; Bauer, JW; Murauer, EM
J INVEST DERMATOL. 2014; 134: S56-S56.
Abstracts (Zeitschrift)

2013

Beiträge in Fachzeitschriften

RNA trans-splicing for genodermatoses.
Bauer, JW; Murauer, EM; Wally, V; Koller, U;
Methods Mol Biol. 2013; 961:441-455
Originalarbeiten (Zeitschrift)
The design and optimization of RNA trans-splicing molecules for skin cancer therapy.
Gruber, C; Koller, U; Murauer, EM; Hainzl, S; Huttner, C; Kocher, T; South, AP; Hintner, H; Bauer, JW
Mol Oncol. 2013; 7(6):105-168
Originalarbeiten (Zeitschrift)
A reporter-based screen to identify potent 3" trans-splicing molecules for endogenous RNA repair.
Murauer, EM; Koller, U; Hainzl, S; Wally, V; Bauer, JW;
Hum Gene Ther Methods. 2013; 24(1):19-27
Originalarbeiten (Zeitschrift)
The pathogenetic role of IL-1β in severe epidermolysis bullosa simplex.
Wally, V; Lettner, T; Peking, P; Peckl-Schmid, D; Murauer, EM; Hainzl, S; Hintner, H; Bauer, JW;
J Invest Dermatol. 2013; 133(7):1901-1903
Letter

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

RNA trans-splicing molecules for targeted suicide gene delivery into cancer cells
Gruber, C; Koller, U; Hainzl, S; Murauer, EM; Huttner, C; South, AP; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2013; 133: S64-S64.
Abstracts (Zeitschrift)

2012

Beiträge in Fachzeitschriften

Spliceosome-mediated trans-splicing: the therapeutic cut and paste.
Wally, V; Murauer, EM; Bauer, JW;
J Invest Dermatol. 2012; 132(8):1959-1966
Übersichtsarbeiten

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Biodegradable and cationic polymer coupled with minicircle COL7A1 for the corrective gene therapy of recessive dystrophic epidermolysis bullosa
Aied, A; Murauer, E; Hu, X; Cutlar, L; Zheng, Y; Pandit, A; Wang, W
J TISSUE ENG REGEN M. 2012; 6: 291-291.
Abstracts (Zeitschrift)
Optimized high throughput screening system for RNA trans-splicing molecules for gene correction in epidermolysis bullosa
Hainzl, S; Koller, U; Murauer, E; Tockner, B; Wally, V; Hintner, H; Bauer, J
J INVEST DERMATOL. 2012; 132: S94-S94.
Abstracts (Zeitschrift)
Double RNA trans-splicing induced gene correction in epidermolysis bullosa
Koller, U; Hainzl, S; Klausegger, A; Wally, V; Murauer, EM; Mayr, E; Gruber, C; Mitchell, L; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2012; 132: S93-S93.
Abstracts (Zeitschrift)
Functional Correction of Mutations in COL7A1 in a RDEB Patient Cellline via 5 xxx trans-splicing
Mayr, E; Koller, U; Murauer, EM; Gruber, C; Kaiser, M; Klausegger, A; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2012; 132: S92-S92.
Abstracts (Zeitschrift)
Screening for highly efficient RTMs to improve 3 xxx trans-splicing for COL7A1 gene
Tockner, B; Murauer, EM; Mayr, E; Wally, V; Koller, U; Hainzl, S; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2012; 132: S95-S95.
Abstracts (Zeitschrift)

2011

Beiträge in Fachzeitschriften

Spliceosome-mediated RNA trans-splicing facilitates targeted delivery of suicide genes to cancer cells.
Gruber, C; Gratz, IK; Murauer, EM; Mayr, E; Koller, U; Bruckner-Tuderman, L; Meneguzzi, G; Hintner, H; Bauer, JW;
Mol Cancer Ther. 2011; 10(2): 233-241.
Originalarbeiten (Zeitschrift)
A novel screening system improves genetic correction by internal exon replacement.
Koller, U; Wally, V; Mitchell, LG; Klausegger, A; Murauer, EM; Mayr, E; Gruber, C; Hainzl, S; Hintner, H; Bauer, JW;
Nucleic Acids Res. 2011; 39(16): e108
Originalarbeiten (Zeitschrift)
Functional correction of type VII collagen expression in dystrophic epidermolysis bullosa.
Murauer, EM; Gache, Y; Gratz, IK; Klausegger, A; Muss, W; Gruber, C; Meneguzzi, G; Hintner, H; Bauer, JW;
J Invest Dermatol. 2011; 131(1):74-83
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Screening for high efficient double RNA trans-splicing molecules to exchange a single exon of the COL17A1 gene
Koller, U; Wally, V; Mitchell, LG; Klausegger, A; Murauer, EM; Mayr, E; Gruber, C; Hainzl, S; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2011; 131: S67-S67.
Abstracts (Zeitschrift)
A 5 xxx trans-splicing gene therapy approach for dystrophic epidermolysis bullosa
Mayr, E; Koller, U; Murauer, EM; Gruber, C; Klausegger, A; Kaiser, M; Bruckner-Tuderman, L; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2011; 131: S68-S68.
Abstracts (Zeitschrift)
A new 3 xxx trans-splicing repair strategy for the COL17A1 gene
Schlager, P; Klausegger, A; Murauer, EM; Tockner, B; Hintner, H; Bauer, JW
EXP DERMATOL. 2011; 20(2): 173-173.
Abstracts (Zeitschrift)
Optimization of 3 xxx trans-splicing in the type VII Collagen gene
Tockner, B; Murauer, EM; Gruber, C; Mayr, E; Schlager, P; Wally, V; Koller, U; Klausegger, A; Hintner, H; Bauer, JW
HUM GENE THER. 2011; 22(10): A53-A53.
Abstracts (Zeitschrift)

2010

Beiträge in Fachzeitschriften

K14 mRNA reprogramming for dominant epidermolysis bullosa simplex.
Wally, V; Brunner, M; Lettner, T; Wagner, M; Koller, U; Trost, A; Murauer, EM; Hainzl, S; Hintner, H; Bauer, JW;
Hum Mol Genet. 2010; 19(23):471-425
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

RNA trans-splicing technology facilitates targeted delivery of a suicide gene to cancer cells
Gruber, C; Gratz, IK; Mayr, E; Murauer, EM; Bruckner-Tuderman, L; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2010; 130: S79-S79.
Abstracts (Zeitschrift)
Improvement of RNA trans-splicing based gene correction using a RTM screening system
Koller, U; Wally, V; Mitchell, LG; Klausegger, A; Murauer, EM; Mayr, E; Gruber, C; Hintner, H; Bauer, JW
HUM GENE THER. 2010; 21(10): 1451-1451.
Abstracts (Zeitschrift)
Screening for the best 5 xxx pre-trans-splicing molecules in COL7A1 in order to develop a 5 xxx trans-splicing gene therapy approach for dystrophic Epidermolysis bullosa
Mayr, E; Koller, U; Murauer, EM; Gruber, C; Klausegger, A; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2010; 130: S80-S80.
Abstracts (Zeitschrift)
Functional correction of recessive dystrophic epidermolysis bullosa by 3xxxtrans-splicing of COL7A1
Murauer, EM; Gache, Y; Laguzzi, FL; Muss, W; Meneguzzi, G; Hintner, HH; Bauer, JW
EXP DERMATOL. 2010; 19(2): 178-178.
Abstracts (Zeitschrift)
3 xxx trans-splicing repair of COL7A1 mutations in recessive dystrophic epidermolysis bullosa patients
Murauer, EM; Gache, Y; Larcher, F; Del Rio, M; Muss, W; Meneguzzi, G; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2010; 130: S75-S75.
Abstracts (Zeitschrift)

2009

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Using RNA Trans-splicing to correct mutations in the plectin gene
Koller, U; Wally, V; Mitchell, LG; Klausegger, A; Murauer, EM; Mayr, E; Hintner, H; Bauer, JW
EXP DERMATOL. 2009; 18(3): 283-283.
Abstracts (Zeitschrift)
5# Trans-splicing in the type vii collagen gene-development of a mRNA based gene therapy approach for dystrophic epidermolysis bullosa
Mayr, E; Koller, U; Murauer, EM; Wally, V; Klausegger, A; Hintner, H; Bauer, JW
EXP DERMATOL. 2009; 18(3): 284-284.
Abstracts (Zeitschrift)
5 xxx trans-splicing in the Type VII Collagen Gene - Development of a mRNA based Gene Therapy Approach for Dystrophic Epidermolysis bullosa
Mayr, E; Koller, U; Murauer, EM; Wally, V; Klausegger, A; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2009; 129: S46-S46.
Abstracts (Zeitschrift)
In vitro Correction of COL7A1 Gene Mutations using RNA Trans-splicing
Murauer, EM; Gache, Y; Gratz, IK; Klausegger, A; Muss, W; Gruber, C; Meneguzzi, G; Hintner, H; Bauer, JW
J INVEST DERMATOL. 2009; 129: S45-S45.
Abstracts (Zeitschrift)
3 xxx Trans-splicing as a tool for gene therapy in dystrophic epidermolysis bullosa
Murauer, EM; Gache, Y; Klausegger, A; Wally, V; Koller, U; Mayr, E; Meneguzzi, G; Bauer, JW
EXP DERMATOL. 2009; 18(3): 283-283.
Abstracts (Zeitschrift)
Gene therapy for autosomal dominant diseases
Wally, V; Koller, U; Murauer, EM; Mayr, E; Klausegger, A; Hintner, H; Bauer, JW
EXP DERMATOL. 2009; 18(3): 283-283.
Abstracts (Zeitschrift)

2008

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

3xxx trans-splicing repair of the COL7A1 gene in epidermolysis bullosa dystrophica patients
Murauer, EM; Klausegger, A; Mitchell, LG; Bauer, JW
HUM GENE THER. 2008; 19(10): 1131-1131.
Abstracts (Zeitschrift)