' '
Deutsch | English    

Forschungsdatenbank PMU-SQQUID

HARTMANN TANJA
Universitätsklinik für Innere Medizin 3 - Hämatologie, internistische Onkologie, Hämostaseologie, Infektiologie, Rheumatologie und Onkologisches Zentrum

Publikationen | Forscherprofil

98 Publikationen

2019

Beiträge in Fachzeitschriften

BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation.
Asslaber, D; Wacht, N; Leisch, M; Qi, Y; Maeding, N; Hufnagl, C; Jansko, B; Zaborsky, N; Villunger, A; Hartmann, TN; Greil, R; Egle, A;
Clin Cancer Res. 2019; 25(6):1901-1912
Originalarbeiten (Zeitschrift)

2018

Beiträge in Fachzeitschriften

Rac GTPases in Hematological Malignancies
Durand-Onayli, V; Haslauer, T; Harzschel, A; Hartmann, TN
INT J MOL SCI. 2018; 19(12): 4041
Übersichtsarbeiten
Remission maintenance treatment options in chronic lymphocytic leukemia.
Egle, A; Pleyer, L; Melchardt, T; Hartmann, TN; Greil, R;
Cancer Treat Rev. 2018; 70:56-66
Übersichtsarbeiten
Correction to: Fludarabine and rituximab with escalating doses of lenalidomide followed by lenalidomide/rituximab maintenance in previously untreated chronic lymphocytic leukaemia (CLL): the REVLIRIT CLL-5 AGMT phase I/II study.
Egle, A; Steurer, M; Melchardt, T; Weiss, L; Gassner, FJ; Zaborsky, N; Geisberger, R; Catakovic, K; Hartmann, TN; Pleyer, L; Voskova, D; Thaler, J; Lang, A; Girschikofsky, M; Petzer, A; Greil, R;
Ann Hematol. 2018; 97(9):1745
Korrekturen
Fludarabine and rituximab with escalating doses of lenalidomide followed by lenalidomide/rituximab maintenance in previously untreated chronic lymphocytic leukaemia (CLL): the REVLIRIT CLL-5 AGMT phase I/II study.
Egle, A; Steurer, M; Melchardt, T; Weiss, L; Gassner, FJ; Zaborsky, N; Geisberger, R; Catakovic, K; Hartmann, TN; Pleyer, L; Voskova, D; Thaler, J; Lang, A; Girschikofsky, M; Petzer, A; Greil, R;
Ann Hematol. 2018; 97(10): 1825-1839.
Originalarbeiten (Zeitschrift)
Microenvironment-induced CD44v6 promotes early disease progression in chronic lymphocytic leukemia.
Gutjahr, JC; Szenes, E; Tschech, L; Asslaber, D; Schlederer, M; Roos, S; Yu, X; Girbl, T; Sternberg, C; Egle, A; Aberger, F; Alon, R; Kenner, L; Greil, R; Orian-Rousseau, V; Hartmann, TN;
Blood. 2018; 131(12): 1337-1349.
Originalarbeiten (Zeitschrift)
Clonal evolution and heterogeneity in metastatic head and neck cancer-An analysis of the Austrian Study Group of Medical Tumour Therapy study group.
Melchardt, T; Magnes, T; Hufnagl, C; Thorner, AR; Ducar, M; Neureiter, D; Tränkenschuh, W; Klieser, E; Gaggl, A; Rösch, S; Rasp, G; Hartmann, TN; Pleyer, L; Rinnerthaler, G; Weiss, L; Greil, R; Egle, A;
Eur J Cancer. 2018; 93:69-78
Originalarbeiten (Zeitschrift)
Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia.
Tissino, E; Benedetti, D; Herman, SEM; Ten Hacken, E; Ahn, IE; Chaffee, KG; Rossi, FM; Dal Bo, M; Bulian, P; Bomben, R; Bayer, E; Härzschel, A; Gutjahr, JC; Postorino, M; Santinelli, E; Ayed, A; Zaja, F; Chiarenza, A; Pozzato, G; Chigaev, A; Sklar, LA; Burger, JA; Ferrajoli, A; Shanafelt, TD; Wiestner, A; Del Poeta, G; Hartmann, TN; Gattei, V; Zucchetto, A;
J Exp Med. 2018; 215(2):681-697
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

The VLA-4 Integrin Is Constitutively Activated in a Subset of CD49d-Expressing CLL: A Relationship with the Autonomous BCR-Mediated Signaling?
Tissino, E; Bittolo, T; Benedetti, D; Bomben, R; Forestieri, G; Szenes, E; Haerzschel, A; Santinelli, E; Rossi, MF; Chigaev, A; Sklar, LA; Zaja, F; Bulian, P; DxxxArena, GF; Chiarenza, A; Di Raimondo, F; Pozzato, G; Rossi, D; Del Poeta, G; Hartmann, TN; Zucchetto, A; Gattei, V
BLOOD. 2018; 132:
Abstracts (Zeitschrift)

2017

Beiträge in Fachzeitschriften

Acute myeloid leukemia - strategies and challenges for targeting oncogenic Hedgehog/GLI signaling.
Aberger, F; Hutterer, E; Sternberg, C; Del Burgo, PJ; Hartmann, TN;
Cell Commun Signal. 2017; 15(1): 8
Übersichtsarbeiten
TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia.
Catakovic, K; Gassner, FJ; Ratswohl, C; Zaborsky, N; Rebhandl, S; Schubert, M; Steiner, M; Gutjahr, JC; Pleyer, L; Egle, A; Hartmann, TN; Greil, R; Geisberger, R;
Oncoimmunology. 2017; 7(1):e1371399
Originalarbeiten (Zeitschrift)
Reactivation of dormant anti-tumor immunity - a clinical perspective of therapeutic immune checkpoint modulation.
Greil, R; Hutterer, E; Hartmann, TN; Pleyer, L;
Cell Commun Signal. 2017; 15(1):5
Übersichtsarbeiten
The sound of tumor cell-microenvironment communication - composed by the Cancer Cluster Salzburg research network.
Wessler, S; Aberger, F; Hartmann, TN;
Cell Commun Signal. 2017; 15(1): 20
Editorials

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

TIGIT as a new target for checkpoint inhibition for chronic lymphocytic leukemia
Catakovic, K; Gassner, F; Rathswohl, C; Greil, R; Hartmann, T; Geisberger, R
LEUKEMIA LYMPHOMA. 2017; 58: 53-54.
Abstracts (Zeitschrift)
CLL cells residing in spleen and bone marrow microenvironments differ in their CD44 variant usage for migration and proliferation
Gutjahr, JC; Szenes, E; Tschech, L; Schlederer, M; Roos, S; Asslaber, D; Girbl, T; Greil, R; Alon, R; Kenner, L; Orian-Rousseau, V; Hartmann, TN
Leukemia & Lymphoma. 2017; 58(sup1):1-240.-iwCLL; 12.05-15.05.2017; New York.
Abstracts (Zeitschrift)
T-cell immune response: a prognostic factor for pathological regression in previously adjuvant treated colorectal cancer liver metastasis
Klieser, E; Krenn, P; Urbas, R; Primavesi, F, Stättner, S; Sotlar, K; Neureiter, D; Hartmann, TN
Der Pathologe. 2017; 38(Supp. 1):S132-S132.-101. Jahrestagung der Deutschen Gesellschaft für Pathologie e. V.; 22.-24.06.2017; Erlangen.
Abstracts (Zeitschrift)
NGS ANALYSIS OF 474 BONE MARROW SAMPLES FROM 157 AML PATIENTS TREATED WITH AZACITIDINE-IMPACT OF AGE ON MUTATIONAL LOAD
Pleyer, L; Gassner, FJ; Burgstaller, S; Wedler, H; Hartmann, TN; Jansko, B; Neureiter, D; Thaler, J; Greil, R
HAEMATOLOGICA. 2017; 102: 215-216.
Abstracts (Zeitschrift)
CLL cells residing in spleen and bone marrow microenvironments differ in their CD44 variant usage for migration and proliferation
Roos, S; Schlederer, M; Hartmann, T; Gutjahr, JC; Szenes, E; Tschech, L; Girbl, T; Greil, R; Kenner, L; Orian-Rousseau, V; Ronen, A
LEUKEMIA LYMPHOMA. 2017; 58: 41-42.
Abstracts (Zeitschrift)
INSIDE-OUT VLA-4 INTEGRIN ACTIVATION IS MAINTAINED IN IBRUTINIB-TREATED CHRONIC LYMPHOCYTIC LEUKEMIA EXPRESSING CD49D: CLINICAL RELEVANCE
Tissino, E; Benedetti, D; Herman, SE; ten Hacken, E; Ahn, IE; Chaffee, KG; Rossi, FM; Dal Bo, M; Bulian, P; Bomben, R; Bayer, E; Harzschel, A; Gutjahr, JC; Postorino, M; Santinelli, E; Ayed, A; Zaja, F; Chiarenza, A; Chigaev, A; Sklar, LA; Burger, JA; Ferrajoli, A; Shanafelt, TD; Wiestner, A; Del Poeta, G; Hartmann, TN; Gattei, V; Zucchetto, A
HAEMATOLOGICA. 2017; 102: 229-229.
Abstracts (Zeitschrift)

2016

Beiträge in Fachzeitschriften

Persistent CD49d engagement in circulating CLL cells: a role for blood-borne ligands?
Benedetti, D; Tissino, E; Caldana, C; Dal Bo, M; Bomben, R; Marconi, D; Ganghammer, S; Zaja, F; Pozzato, G; Di Raimondo, F; Hartmann, TN; Del Poeta, G; VanMeter, A; Zucchetto, A; Espina, V; Liotta, L; Gattei, V;
Leukemia. 2016; 30(2): 513-517.
Letter
Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative co-operativity of the receptors.
Ganghammer, S; Gutjahr, J; Hutterer, E; Krenn, PW; Pucher, S; Zelle-Rieser, C; Jöhrer, K; Wijtmans, M; Leurs, R; Smit, MJ; Gattei, V; Greil, R; Hartmann, TN;
Haematologica. 2016; 101(3):e99-102
Letter
BCR and chemokine responses upon anti-IgM and anti-IgD stimulation in chronic lymphocytic leukaemia.
Haerzschel, A; Catusse, J; Hutterer, E; Paunovic, M; Zirlik, K; Eibel, H; Krenn, PW; Hartmann, TN; Burger, M;
Ann Hematol. 2016; 95(12): 1979-1988.
Originalarbeiten (Zeitschrift)
The AKT1 isoform plays a dominant role in the survival and chemoresistance of chronic lymphocytic leukaemia cells.
Hofbauer, SW; Krenn, PW; Piñόn Hofbauer, J; Pucher, S; Asslaber, D; Egle, A; Hartmann, TN; Greil, R;
Br J Haematol. 2016; 172(5):815-819
Letter
CD4+ T cells, but not non-classical monocytes, are dispensable for the development of chronic lymphocytic leukemia in the TCL1-tg murine model.
Kocher, T; Asslaber, D; Zaborsky, N; Flenady, S; Denk, U; Reinthaler, P; Ablinger, M; Geisberger, R; Bauer, JW; Seiffert, M; Hartmann, TN; Greil, R; Egle, A; Piñón Hofbauer, J;
Leukemia. 2016; 30(6):1409-1413
Letter
ILK Induction in Lymphoid Organs by a TNFα-NF-κB-Regulated Pathway Promotes the Development of Chronic Lymphocytic Leukemia.
Krenn, PW; Hofbauer, SW; Pucher, S; Hutterer, E; Hinterseer, E; Denk, U; Asslaber, D; Ganghammer, S; Sternberg, C; Neureiter, D; Aberger, F; Wickström, SA; Egle, A; Greil, R; Hartmann, TN;
Cancer Res. 2016; 76(8):218-296
Originalarbeiten (Zeitschrift)
Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones.
Melchardt, T; Hufnagl, C; Weinstock, DM; Kopp, N; Neureiter, D; Tränkenschuh, W; Hackl, H; Weiss, L; Rinnerthaler, G; Hartmann, TN; Greil, R; Weigert, O; Egle, A;
Oncotarget. 2016; 7(32):51494-51502
Originalarbeiten (Zeitschrift)
CD44: More than a mere stem cell marker.
Morath, I; Hartmann, TN; Orian-Rousseau, V;
Int J Biochem Cell Biol. 2016; 81(Pt A):166-173
Originalarbeiten (Zeitschrift)
Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress.
Shatirishvili, M; Burk, AS; Franz, CM; Pace, G; Kastilan, T; Breuhahn, K; Hinterseer, E; Dierich, A; Bakiri, L; Wagner, EF; Ponta, H; Hartmann, TN; Tanaka, M; Orian-Rousseau, V;
Cell Death Dis. 2016; 7(11): e2461
Originalarbeiten (Zeitschrift)
Ibrutinib Inhibits VLA-4-Dependent Adhesion in CLL-Letter
Zucchetto, A; Tissino, E; Hartmann, TN; Chigaev, A; Del Poeta, G; Colombatti, A; Gattei, V
CLIN CANCER RES. 2016; 22(13): 3410-3411.
Letter

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

CXCL12 ANTAGONISM BY THE L-RNA APTAMER OLAPTESED PEGOL IS EFFECTIVE AS A MOBILIZING AND THERAPEUTIC AGENT IN A MURINE CHRONIC LYMPHOCYTIC LEUKEMIA MODEL
Hinterseer, E; Hutterer, E; Krenn, PW; Reinthaler, P; Hopner, J; Hopfinger, M; Eulberg, D; Maasch, C; Kruschinski, A; Vater, A; Egle, A; Greil, R; Hartmann, TN
HAEMATOLOGICA. 2016; 101: 45-46.
Abstracts (Zeitschrift)
A CXCR4 inhibitor and Btk inhibitor ONO/GS-4059 are synergistic and result in loss of CLL cell migratory ability and survival
Lewis, T; Proctor, VK; Brennan, P; Pratt, G; Hartmann, TN; Buggins, AGS; Yoshizawa, T; Fegan, C; Pepper, C; Walsby, EJ
BRIT J HAEMATOL. 2016; 173: 8-8.
Abstracts (Zeitschrift)
Blocking CD62L inhibits CLL cell interaction with vascular endothelium; an effect that is augmented by ibrutinib
Shere, C; Hartmann, TN; Pratt, G; Fegan, C; Pepper, C; Walsby, EJ
BRIT J HAEMATOL. 2016; 173: 7-8.
Abstracts (Zeitschrift)
CD49D EXPRESSION IMPACTS ON THE IBRUTINIB-INDUCED LYMPHOCYTOSIS IN CHRONIC LYMPHOCYTIC LEUKEMIA: A ROLE OF BCR-MEDIATED INSIDE-OUT VLA-4 INTEGRIN ACTIVATION
Tissino, E; Caldana, C; Benedetti, D; Herman, SE; ten Hacken, E; Rossi, FM; Dal Bo, M; Bulian, P; Bomben, R; Zaja, F; Chiarenza, A; Sklar, LA; Hartmann, TN; Chigaev, A; Burger, JA; Del Poeta, G; Wiestner, A; Gattei, V; Zucchetto, A
HAEMATOLOGICA. 2016; 101: 49-50.
Abstracts (Zeitschrift)

2015

Beiträge in Fachzeitschriften

CXCL12-induced VLA-4 activation is impaired in trisomy 12 chronic lymphocytic leukemia cells: a role for CCL21.
Ganghammer, S; Hutterer, E; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, PW; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Kruschinski, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, TN;
Oncotarget. 2015; 6(14):12048-12060
Originalarbeiten (Zeitschrift)
Chronic lymphocytic leukaemia induces an exhausted T cell phenotype in the TCL1 transgenic mouse model.
Gassner, FJ; Zaborsky, N; Catakovic, K; Rebhandl, S; Huemer, M; Egle, A; Hartmann, TN; Greil, R; Geisberger, R;
Br J Haematol. 2015; 170(4):515-522
Originalarbeiten (Zeitschrift)
The Role of CD44 in the Pathophysiology of Chronic Lymphocytic Leukemia.
Gutjahr, JC; Greil, R; Hartmann, TN;
Front Immunol. 2015; 6:177
Übersichtsarbeiten
VLA-4 and CXCR4 overexpression in bone marrow of an aleukemic B-cell acute lymphoblastic leukemia presenting with osteolytic bone lesions.
Hinterseer, E; Stiefel, O; Neureiter, D; Kandler, G; Vogt, S; Hutter, J; Strasser, G; Greil, R; Hartmann, TN; Hopfinger, G;
Leuk Lymphoma. 2015; 56(8):2465-2467
Letter
CD18 (ITGB2) expression in chronic lymphocytic leukaemia is regulated by DNA methylation-dependent and -independent mechanisms.
Hutterer, E; Asslaber, D; Caldana, C; Krenn, PW; Zucchetto, A; Gattei, V; Greil, R; Hartmann, TN;
Br J Haematol. 2015; 169(2):286-289
Letter
Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia.
Kern, D; Regl, G; Hofbauer, SW; Altenhofer, P; Achatz, G; Dlugosz, A; Schnidar, H; Greil, R; Hartmann, TN; Aberger, F;
Oncogene. 2015; 34(42):534-551
Originalarbeiten (Zeitschrift)
Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation.
Merkel, O; Hamacher, F; Griessl, R; Grabner, L; Schiefer, AI; Prutsch, N; Baer, C; Egger, G; Schlederer, M; Krenn, PW; Hartmann, TN; Simonitsch-Klupp, I; Plass, C; Staber, PB; Moriggl, R; Turner, SD; Greil, R; Kenner, L;
J Pathol. 2015; 236(4):445-456
Originalarbeiten (Zeitschrift)
B-cell receptor usage correlates with the sensitivity to CD40 stimulation and the occurrence of CD4+ T-cell clonality in chronic lymphocytic leukemia.
Zaborsky, N; Holler, C; Geisberger, R; Asslaber, D; Gassner, FJ; Egger, V; Piñón-Hofbauer, J; Kocher, T; Hartmann, TN; Greil, R; Egle, A;
Haematologica. 2015; 100(8):e307-e310
Letter

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

PGDFR blockade as a novel therapy for NPM-ALK(+) anaplastic large cell lymphoma
Kenner, L; Kuroll, M; Hartmann, T; Krenn, P; Schlederer, M; Prutsch, N; Greil, R; Turner, S; Merkel, O
BRIT J HAEMATOL. 2015; 171: 28-28.
Abstracts (Zeitschrift)
Integrin-linked kinase is induced by TNF alpha-NF-kappa B signals and required for centrosome clustering and mitotic spindle organization during chronic lymphocytic leukemia cell cycle progression
Krenn, P; Hofbauer, S; Pucher, S; Hutterer, E; Hinterseer, E; Asslaber, D; Sternberg, C; Neureiter, D; Aberger, F; Wickstroem, S; Greil, R; Hartmann, TN
ONCOL RES TREAT. 2015; 38: 200-201.
Abstracts (Zeitschrift)
Integrin-linked kinase is induced by TNF alpha- NF-kappa B signals and required for centrosome clustering and mitotic spindle organization during chronic lymphocytic leukemia cell cycle progression
Krenn, PW; Hofbauer, SW; Pucher, S; Hutterer, E; Hinterseer, E; Asslaber, D; Sternberg, C; Neureiter, D; Aberger, F; Wickstrom, SA; Greil, R; Hartmann, TN
LEUKEMIA LYMPHOMA. 2015; 56: 65-67.
Abstracts (Zeitschrift)
Retention of inside-out VLA-4 Integrin Activation upon B-Cell Receptor Triggering in in-Vitro and in-Vivo Ibrutinib Treated Chronic Lymphocytic Leukemia Cells: Clinical Implication
Tissino, E; Caldana, C; Benedetti, D; Rossi, F; Dal Bo, M; Bulian, P; Bomben, R; Zaja, F; Chiarenza, A; Hartmann, TN; Chigaev, A; Del Poeta, G; Gattei, V; Zucchetto, A
BLOOD. 2015; 126(23):
Abstracts (Zeitschrift)

2014

Beiträge in Fachzeitschriften

The pathogenic relevance of the prognostic markers CD38 and CD49d in chronic lymphocytic leukemia.
Brachtl, G; Piñón Hofbauer, J; Greil, R; Hartmann, TN;
Ann Hematol. 2014; 93(3): 361-374.
Übersichtsarbeiten
Chemotherapy-induced augmentation of T cells expressing inhibitory receptors is reversed by treatment with lenalidomide in chronic lymphocytic leukemia.
Gassner, FJ; Zaborsky, N; Neureiter, D; Huemer, M; Melchardt, T; Egle, A; Rebhandl, S; Catakovic, K; Hartmann, TN; Greil, R; Geisberger, R;
Haematologica. 2014; 99(5):67-69
Letter
The CXCR4 and adhesion molecule expression of CD34+ hematopoietic cells mobilized by "on-demand" addition of plerixafor to granulocyte-colony-stimulating factor.
Girbl, T; Lunzer, V; Greil, R; Namberger, K; Hartmann, TN
TRANSFUSION. 2014; 54(9): 2325-2335.
Originalarbeiten (Zeitschrift)
Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade.
Grössinger, EM; Weiss, L; Zierler, S; Rebhandl, S; Krenn, PW; Hinterseer, E; Schmölzer, J; Asslaber, D; Hainzl, S; Neureiter, D; Egle, A; Piñón-Hofbauer, J; Hartmann, TN; Greil, R; Kerschbaum, HH;
Leukemia. 2014; 28(4):954-958
Letter
CLL cells under flow.
Hartmann, TN
BLOOD. 2014; 123(23): 3533-3534.
Kurzberichte/Notes
Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells.
Hofbauer, SW; Krenn, PW; Ganghammer, S; Asslaber, D; Pichler, U; Oberascher, K; Henschler, R; Wallner, M; Kerschbaum, H; Greil, R; Hartmann, TN;
Blood. 2014; 123(14):2181-2188
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

The Transcription Factor IRF4 Is Crucial for CLL Progression and Regulates Survival and Proliferation in a Microenvironment Related Manner
Asslaber, D; Hofbauer, JP; Zaborsky, N; Flenady, S; Hartmann, TN; Greil, R; Egle, A
BLOOD. 2014; 124(21):
Abstracts (Zeitschrift)
The integrin VLA-4 shows impaired CXCL12-induced inside-out activation in trisomy12 harboring chronic lymphocytic leukemia (CLL) cells
Ganghammer, S; Hutterer, E; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, PW; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, TN
ONCOL RES TREAT. 2014; 37: 222-222.
Abstracts (Zeitschrift)
The Spiegelmer (R) NOX-A12 Mobilizes CLL Cells from Lymphoid Organs and Prevents Their Recirculation
Hinterseer, E; Girbl, T; Hutterer, E; Berghammer, P; Ganghammer, S; Sifft, EA; Pinon-Hofbauer, J; Egle, A; Kruschinski, A; Greil, R; Hartmann, TN
SCAND J IMMUNOL. 2014; 79(6): 468-469.
Abstracts (Zeitschrift)
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner
Hutterer, E; Ganghammer, S; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, P; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, T
SCAND J IMMUNOL. 2014; 79(6): 468-468.
Abstracts (Zeitschrift)
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner
Hutterer, E; Ganghammer, S; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, P; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, T
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner. 2014; 79(6): 424-478.-Scandinavian Society for Immunology 42nd Annual Meeting; 11.-14.06.2014; Reykjavik.
Abstracts (Zeitschrift)
CXCL12 Enhances CLL Cell and T-Cell Migration in a Dynamic Circulating Model of CLL That Can be Abrogated By the CXCR4 Antagonist ONO-7161
Walsby, EJ; Brennan, P; Pratt, G; Hartmann, TN; Yoshizawa, T; Fegan, C; Pepper, C
BLOOD. 2014; 124(21):
Abstracts (Zeitschrift)

2013

Beiträge in Fachzeitschriften

Mimicking the microenvironment in chronic lymphocytic leukaemia - where does the journey go?
Asslaber, D; Grössinger, EM; Girbl, T; Hofbauer, SW; Egle, A; Weiss, L; Greil, R; Hartmann, TN;
Br J Haematol. 2013; 160(5):711-714
Letter
CD40-mediated activation of chronic lymphocytic leukemia cells promotes their CD44-dependent adhesion to hyaluronan and restricts CCL21-induced motility.
Girbl, T; Hinterseer, E; Grössinger, EM; Asslaber, D; Oberascher, K; Weiss, L; Hauser-Kronberger, C; Neureiter, D; Kerschbaum, H; Naor, D; Alon, R; Greil, R; Hartmann, TN;
Cancer Res. 2013; 73(2): 561-570.
Originalarbeiten (Zeitschrift)
CD49d is overexpressed by trisomy 12 chronic lymphocytic leukemia cells: evidence for a methylation-dependent regulation mechanism.
Zucchetto, A; Caldana, C; Benedetti, D; Tissino, E; Rossi, FM; Hutterer, E; Pozzo, F; Bomben, R; Dal Bo, M; DxxxArena, G; Zaja, F; Pozzato, G; Di Raimondo, F; Hartmann, TN; Rossi, D; Gaidano, G; Del Poeta, G; Gattei, V
BLOOD. 2013; 122(19): 3317-3321.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

The transcription factor IRF-4 is related to prognosis in Chronic Lymphocytic Leukemia (CLL) and involved in proliferation and survival
Asslaber, D; Hofbauer, JP; Zaborsky, N; Kocher, T; Hartmann, TN; Greil, R; Egle, A
ONKOLOGIE. 2013; 36: 222-223.
Abstracts (Zeitschrift)
CXCR3 modulates CXCL12-mediated cellular responses in chronic lymphocytic leukemia
Ganghammer, S; Hinterseer, E; Johrer, K; Greil, R; Hartmann, TN
CYTOKINE. 2013; 63(3): 264-264.
Abstracts (Zeitschrift)
Blockade of the Potassium Channel KCa3.1 inhibits proliferation in Chronic Lymphocytic Leukemia
Grossinger, EM; Weiss, L; Zierler, S; Hinterseer, E; Schmolzer, J; Asslaber, D; Hainzl, S; Egle, A; Pinon, JD; Hartmann, TN; Greil, R; Kerschbaum, HH
ONKOLOGIE. 2013; 36: 191-192.
Abstracts (Zeitschrift)
Tiam1/Rac1 signals contribute to CLL cell proliferation and chemoresistance
Hofbauer, SW; Krenn, PW; Ganghammer, S; Asslaber, D; Pichler, U; Wallner, M; Henschler, R; Greil, R; Hartmann, TN
ONKOLOGIE. 2013; 36: 56-56.
Abstracts (Zeitschrift)
Antiapoptotic effects of p21 regarding its subcellular localization in arsenic trioxide induced apoptosis in CLL
Sifft, E; Hofbauer, JP; Asslaber, D; Hartmann, TN; Merkel, O; Greil, R
ONKOLOGIE. 2013; 36: 222-222.
Abstracts (Zeitschrift)

2012

Beiträge in Fachzeitschriften

Canonical and noncanonical Hedgehog/GLI signaling in hematological malignancies.
Aberger, F; Kern, D; Greil, R; Hartmann, TN;
Vitam Horm. 2012; 88:2-54
Übersichtsarbeiten
Chemokine-dependent B cell-T cell interactions in chronic lymphocytic leukemia and multiple myeloma - targets for therapeutic intervention?
Jöhrer, K; Hofbauer, SW; Zelle-Rieser, C; Greil, R; Hartmann, TN;
Expert Opin Biol Ther. 2012; 12(4):425-441
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

T Cell Exhaustion Contributes to Immune Evasion in Chronic Lymphocytic Leukaemia
Gassner, FJ; Zaborsky, N; Neureiter, D; Huemer, M; Egle, A; Hartmann, TN; Greil, R; Geisberger, R
BLOOD. 2012; 120(21):
Abstracts (Zeitschrift)
The role of the atypical chemokine receptor CCRL2 (CRAM) in shaping local chemokine gradients
Haerzschel, A; Leick, M; Catusse, J; Hinterseer, E; Hartmann, T; Burger, M
IMMUNOLOGY. 2012; 137: 193-194.
Abstracts (Zeitschrift)

Beiträge in Sonstigen Zeitschriften

KCa3.1 Blockers Inhibit Cell Proliferation in Chronic Lymphocytic Leukemia
Groessinger, EM; Weiss, L; Hinterseer, E; Schmoelzer, J; Oberascher, K; Asslaber, A; Egle, A; Hartmann, TN; Greil, R; Kerschbaum, HH
Blood (ASH Annual Meeting Abstracts) 2012. 2012. #3887:

2011

Beiträge in Fachzeitschriften

Differential bone marrow homing capacity of VLA-4 and CD38 high expressing chronic lymphocytic leukemia cells.
Brachtl, G; Sahakyan, K; Denk, U; Girbl, T; Alinger, B; Hofbauer, SW; Neureiter, D; Hofbauer, JP; Egle, A; Greil, R; Hartmann, TN;
PLoS One. 2011; 6(8):e23758
Originalarbeiten (Zeitschrift)
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner, FJ; Weiss, L; Geisberger, R; Hofbauer, JP; Egle, A; Hartmann, TN; Greil, R; Tinhofer, I;
Cancer Immunol Immunother. 2011; 60(1):7-85
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

CD44-hyaluronan interactions in the pathophysiology of chronic lymphocytic leukemia - regulation by cell activation
Girbl, T; Asslaber, D; Brachtl, G; Denk, U; Weiss, L; Naor, D; Greil, R; Hartmann, TN
ONKOLOGIE. 2011; 34: 140-140.
Abstracts (Zeitschrift)

2010

Beiträge in Fachzeitschriften

Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
Desch, P; Asslaber, D; Kern, D; Schnidar, H; Mangelberger, D; Alinger, B; Stoecher, M; Hofbauer, SW; Neureiter, D; Tinhofer, I; Aberger, F; Hartmann, TN; Greil, R;
Oncogene. 2010; 29(35): 488-495.
Originalarbeiten (Zeitschrift)
Over-expression of bacterial gamma-glutamylcysteine synthetase (GSH1) in plastids affects photosynthesis, growth and sulphur metabolism in poplar (Populus tremula x Populus alba) dependent on the resulting gamma-glutamylcysteine and glutathione levels.
Herschbach, C; Rizzini, L; Mult, S; Hartmann, T; Busch, F; Peuke, AD; Kopriva, S; Ensminger, I;
PLANT CELL ENVIRON. 2010; 33(7): 1138-1151.
Originalarbeiten (Zeitschrift)
Modifying akt signaling in B-cell chronic lymphocytic leukemia cells.
Hofbauer, SW; Piñón, JD; Brachtl, G; Haginger, L; Wang, W; Jöhrer, K; Tinhofer, I; Hartmann, TN; Greil, R;
Cancer Res. 2010; 70(18):7336-7344
Originalarbeiten (Zeitschrift)
CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B
Leick, M; Catusse, J; Follo, M; Nibbs, RJ; Hartmann, TN; Veelken, H; Burger, M
IMMUNOLOGY. 2010; 129(4): 536-546.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

VLA-4 and CD38 in chronic lymphocytic leukemia - more than prognostic markers?
Brechtl, G; Denk, U; Pinon-Hofbauer, JD; Greil, R; Hartmann, TN
ONKOLOGIE. 2010; 33: 201-202.
Abstracts (Zeitschrift)
The role of the VLA-4 integrin in adhesion and survival of chronic lymphocytic leukemia (CLL) cells
Sahakyan, K; Hofbauer, S; Brachtl, G; Girbl, T; Henschler, R; Greil, R; Hartmann, TN
ONKOLOGIE. 2010; 33: 201-201.
Abstracts (Zeitschrift)

Beiträge in Sonstigen Zeitschriften

ÖGHO-Frühjahrstagung: Chronische Lymphatische Leukämie, Adhäsionsmoleküle als mögliche therapeutische Ziele.
Hartmann, TN
JATROS Haematologie und Onkologie. 3/2010. 2010. 63-65.
Erforschung der Chronisch Lymphatischen Leukämie am LIMCR.
Hartmann, TN
Med.ium. 6/2010.. 2010.

2009

Beiträge in Fachzeitschriften

Circulating B-cell chronic lymphocytic leukemia cells display impaired migration to lymph nodes and bone marrow.
Hartmann, TN; Grabovsky, V; Wang, W; Desch, P; Rubenzer, G; Wollner, S; Binsky, I; Vallon-Eberhard, A; Sapoznikov, A; Burger, M; Shachar, I; Haran, M; Honczarenko, M; Greil, R; Alon, R;
Cancer Res. 2009; 69(7):3121-3130
Originalarbeiten (Zeitschrift)
Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.
Hartmann, TN; Pleyer, L; Desch, P; Egle, A; Greil, R;
Discov Med. 2009; 8(42): 157-164.
Übersichtsarbeiten
Alternative implication of CXCR4 in JAK2/STAT3 activation in small cell lung cancer.
Pfeiffer, M; Hartmann, TN; Leick, M; Catusse, J; Schmitt-Graeff, A; Burger, M;
BRIT J CANCER. 2009; 100(12): 1949-1956.
Originalarbeiten (Zeitschrift)
Molecular and cellular mechanisms of CLL: novel therapeutic approaches.
Pleyer, L; Egle, A; Hartmann, TN; Greil, R;
NAT REV CLIN ONCOL. 2009; 6(7): 405-418.
Übersichtsarbeiten

2008

Beiträge in Fachzeitschriften

A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells.
Hartmann, TN; Grabovsky, V; Pasvolsky, R; Shulman, Z; Buss, EC; Spiegel, A; Nagler, A; Lapidot, T; Thelen, M; Alon, R;
J LEUKOCYTE BIOL. 2008; 84(4): 113-140.
Originalarbeiten (Zeitschrift)
Human B cells express the orphan chemokine receptor CRAM-A/B in a maturation-stage-dependent and CCL5-modulated manner.
Hartmann, TN; Leick, M; Ewers, S; Diefenbacher, A; Schraufstatter, I; Honczarenko, M; Burger, M;
Immunology. 2008; 125(2):252-262
Originalarbeiten (Zeitschrift)

2007

Beiträge in Fachzeitschriften

Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces.
Woolf, E; Grigorova, I; Sagiv, A; Grabovsky, V; Feigelson, SW; Shulman, Z; Hartmann, T; Sixt, M; Cyster, JG; Alon, R;
Nat Immunol. 2007; 8(10):1076-1085
Originalarbeiten (Zeitschrift)

2005

Beiträge in Fachzeitschriften

KSHV-GPCR and CXCR2 transforming capacity and angiogenic responses are mediated through a JAK2-STAT3-dependent pathway.
Burger, M; Hartmann, T; Burger, JA; Schraufstatter, I;
Oncogene. 2005; 24(12):2067-2075
Originalarbeiten (Zeitschrift)
Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells.
Burger, M; Hartmann, T; Krome, M; Rawluk, J; Tamamura, H; Fujii, N; Kipps, TJ; Burger, JA;
Blood. 2005; 106(5):1824-1830
Originalarbeiten (Zeitschrift)
CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells.
Hartmann, TN; Burger, JA; Glodek, A; Fujii, N; Burger, M;
Oncogene. 2005; 24(27):4462-4471
Originalarbeiten (Zeitschrift)
Expression profiling of metabolic genes in response to methyl jasmonate reveals regulation of genes of primary and secondary sulfur-related pathways in Arabidopsis thaliana.
Jost, R; Altschmied, L; Bloem, E; Bogs, J; Gershenzon, J; Hähnel, U; Hänsch, R; Hartmann, T; Kopriva, S; Kruse, C; Mendel, RR; Papenbrock, J; Reichelt, M; Rennenberg, H; Schnug, E; Schmidt, A; Textor, S; Tokuhisa, J; Wachter, A; Wirtz, M; Rausch, T; Hell, R;
Photosynth Res. 2005; 86(3):491-508
Originalarbeiten (Zeitschrift)

2004

Beiträge in Fachzeitschriften

Regulation of sulphate assimilation by glutathione in poplars (Populus tremula x P. alba) of wild type and overexpressing gamma-glutamylcysteine synthetase in the cytosol.
Hartmann, T; Hönicke, P; Wirtz, M; Hell, R; Rennenberg, H; Kopriva, S;
J Exp Bot. 2004; 55(398):837-845
Originalarbeiten (Zeitschrift)
The role of adhesion molecules and chemokine receptor CXCR4 (CD184) in small cell lung cancer.
Hartmann, TN; Burger, M; Burger, JA;
J Biol Regul Homeost Agents. 2004; 18(2):126-130
Übersichtsarbeiten
Regulation of sulfate assimilation by nitrogen and sulfur nutrition in poplar trees
Kopriva, S; Hartmann, T; Massaro, G; Honicke, P; Rennenberg, H
TREES-STRUCT FUNCT. 2004; 18(3): 320-326.
Originalarbeiten (Zeitschrift)

2003

Beiträge in Fachzeitschriften

Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells.
Burger, M; Glodek, A; Hartmann, T; Schmitt-Gräff, A; Silberstein, LE; Fujii, N; Kipps, TJ; Burger, JA;
Oncogene. 2003; 22(50):8093-8101
Originalarbeiten (Zeitschrift)
Cell-specific measurement of cytosolic glutathione in poplar leaves.
Hartmann, TN; Fricker, MD; Rennenberg, H; Meyer, AJ;
Plant Cell Environ. 2003; 26(6):965-975
Originalarbeiten (Zeitschrift)

2000

Beiträge in Fachzeitschriften

Leaf age-dependent differences in sulphur assimilation and allocation in poplar (Populus tremula x P. alba) leaves.
Hartmann, T; Mult, S; Suter, M; Rennenberg, H; Herschbach, C;
J Exp Bot. 2000; 51(347):1077-1088
Originalarbeiten (Zeitschrift)