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Forschungsdatenbank PMU-SQQUID

GEISBERGER ROLAND
Universitätsklinik für Innere Medizin 3 - Hämatologie, internistische Onkologie, Hämostaseologie, Infektiologie, Rheumatologie und Onkologisches Zentrum

Publikationen | Forscherprofil

47 Publikationen

2019

Beiträge in Fachzeitschriften

Exome sequencing of the TCL1 mouse model for CLL reveals genetic heterogeneity and dynamics during disease development.
Zaborsky, N; Gassner, FJ; Höpner, JP; Schubert, M; Hebenstreit, D; Stark, R; Asslaber, D; Steiner, M; Geisberger, R; Greil, R; Egle, A;
Leukemia. 2019; 33(4):957-968
Originalarbeiten (Zeitschrift)

2018

Beiträge in Fachzeitschriften

Fludarabine and rituximab with escalating doses of lenalidomide followed by lenalidomide/rituximab maintenance in previously untreated chronic lymphocytic leukaemia (CLL): the REVLIRIT CLL-5 AGMT phase I/II study.
Egle, A; Steurer, M; Melchardt, T; Weiss, L; Gassner, FJ; Zaborsky, N; Geisberger, R; Catakovic, K; Hartmann, TN; Pleyer, L; Voskova, D; Thaler, J; Lang, A; Girschikofsky, M; Petzer, A; Greil, R;
Ann Hematol. 2018; 97(10): 1825-1839.
Originalarbeiten (Zeitschrift)
Correction to: Fludarabine and rituximab with escalating doses of lenalidomide followed by lenalidomide/rituximab maintenance in previously untreated chronic lymphocytic leukaemia (CLL): the REVLIRIT CLL-5 AGMT phase I/II study.
Egle, A; Steurer, M; Melchardt, T; Weiss, L; Gassner, FJ; Zaborsky, N; Geisberger, R; Catakovic, K; Hartmann, TN; Pleyer, L; Voskova, D; Thaler, J; Lang, A; Girschikofsky, M; Petzer, A; Greil, R;
Ann Hematol. 2018; 97(9):1745
Korrekturen
Imprecision and DNA Break Repair Biased towards Incompatible End Joining in Leukemia.
Gassner, FJ; Schubert, M; Rebhandl, S; Spandl, K; Zaborsky, N; Catakovic, K; Blaimer, S; Hebenstreit, D; Greil, R; Geisberger, R;
Mol Cancer Res. 2018; 16(3):428-438
Originalarbeiten (Zeitschrift)
Risks and chances of aberrant DNA repair in cancer.
Schubert, M; Greil, R; Geisberger, R;
Oncoscience. 2018; 5(9-10): 256-257.
Editorials
Investigating epigenetic effects of activation-induced deaminase in chronic lymphocytic leukemia.
Schubert, M; Hackl, H; Gassner, FJ; Greil, R; Geisberger, R;
PLoS One. 2018; 13(12): e0208753
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Exome sequencing of tumors from the TCL1 mouse model for CLL reveals genetic heterogeneity and dynamics during disease development
Egle, A; Gassner, FJ; Hopner, JP; Hebenstreit, D; Stark, R; Asslaber, D; Steiner, M; Geisberger, R; Greil, R; Zaborsky, N
ONCOL RES TREAT. 2018; 41: 31-31.
Abstracts (Zeitschrift)
RNA editing in CLL
Gassner, FJ; Zaborsky, N; Sychikow, I; Levanon, E; Greil, R; Geisberger, R
ONCOL RES TREAT. 2018; 41: 169-169.
Abstracts (Zeitschrift)
Evaluation of circulating cell-free DNA as a molecular monitoring tool in patients with metastatic cancer
Hufnagl, C; Leisch, M; Weiss, L; Melchardt, T; Moik, M; Geisberger, R; Asslaber, D; Steininger, P; Meissnitzer, T; Neureiter, D; Greil, R; Egle, A
ONCOL RES TREAT. 2018; 41: 307-307.
Abstracts (Zeitschrift)
Elucidating the contribution of AID to the clonal evolution of chronic lymphocytic leukemia
Schubert, M; Zaborsky, N; Huemer, M; Hopner, JP; Gassner, FJ; Arzt, C; Greil, R; Geisberger, R
ONCOL RES TREAT. 2018; 41: 169-169.
Abstracts (Zeitschrift)

2017

Beiträge in Fachzeitschriften

The Human NADPH Oxidase, Nox4, Regulates Cytoskeletal Organization in Two Cancer Cell Lines, HepG2 and SH-SY5Y.
Auer, S; Rinnerthaler, M; Bischof, J; Streubel, MK; Breitenbach-Koller, H; Geisberger, R; Aigner, E; Cadamuro, J; Richter, K; Sopjani, M; Haschke-Becher, E; Felder, TK; Breitenbach, M;
Front Oncol. 2017; 7: 111
Originalarbeiten (Zeitschrift)
TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia.
Catakovic, K; Gassner, FJ; Ratswohl, C; Zaborsky, N; Rebhandl, S; Schubert, M; Steiner, M; Gutjahr, JC; Pleyer, L; Egle, A; Hartmann, TN; Greil, R; Geisberger, R;
Oncoimmunology. 2017; 7(1):e1371399
Originalarbeiten (Zeitschrift)
T cell exhaustion: from pathophysiological basics to tumor immunotherapy.
Catakovic, K; Klieser, E; Neureiter, D; Geisberger, R;
Cell Commun Signal. 2017; 15(1):
Übersichtsarbeiten

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

TIGIT as a new target for checkpoint inhibition for chronic lymphocytic leukemia
Catakovic, K; Gassner, F; Rathswohl, C; Greil, R; Hartmann, T; Geisberger, R
LEUKEMIA LYMPHOMA. 2017; 58: 53-54.
Abstracts (Zeitschrift)

2016

Beiträge in Fachzeitschriften

CD4+ T cells, but not non-classical monocytes, are dispensable for the development of chronic lymphocytic leukemia in the TCL1-tg murine model.
Kocher, T; Asslaber, D; Zaborsky, N; Flenady, S; Denk, U; Reinthaler, P; Ablinger, M; Geisberger, R; Bauer, JW; Seiffert, M; Hartmann, TN; Greil, R; Egle, A; Piñón Hofbauer, J;
Leukemia. 2016; 30(6):1409-1413
Letter
CD1d expression on chronic lymphocytic leukemia B cells affects disease progression and induces T cell skewing in CD8 positive and CD4CD8 double negative T cells.
Zaborsky, N; Gassner, FJ; Asslaber, D; Reinthaler, P; Denk, U; Flenady, S; Hofbauer, JP; Danner, B; Rebhandl, S; Harrer, A; Geisberger, R; Greil, R; Egle, A;
Oncotarget. 2016; 7(31):4945-49469
Originalarbeiten (Zeitschrift)

2015

Beiträge in Fachzeitschriften

CXCL12-induced VLA-4 activation is impaired in trisomy 12 chronic lymphocytic leukemia cells: a role for CCL21.
Ganghammer, S; Hutterer, E; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, PW; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Kruschinski, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, TN;
Oncotarget. 2015; 6(14):12048-12060
Originalarbeiten (Zeitschrift)
Chronic lymphocytic leukaemia induces an exhausted T cell phenotype in the TCL1 transgenic mouse model.
Gassner, FJ; Zaborsky, N; Catakovic, K; Rebhandl, S; Huemer, M; Egle, A; Hartmann, TN; Greil, R; Geisberger, R;
Br J Haematol. 2015; 170(4):515-522
Originalarbeiten (Zeitschrift)
AIDing cancer treatment: Reducing AID activity via HSP90 inhibition.
Rebhandl, S; Geisberger, R;
Eur J Immunol. 2015; 45(8): 2208-2211.
Originalarbeiten (Zeitschrift)
AID/APOBEC deaminases and cancer.
Rebhandl, S; Huemer, M; Greil, R; Geisberger, R;
Oncoscience. 2015; 2(4):320-333
Übersichtsarbeiten
B-cell receptor usage correlates with the sensitivity to CD40 stimulation and the occurrence of CD4+ T-cell clonality in chronic lymphocytic leukemia.
Zaborsky, N; Holler, C; Geisberger, R; Asslaber, D; Gassner, FJ; Egger, V; Piñón-Hofbauer, J; Kocher, T; Hartmann, TN; Greil, R; Egle, A;
Haematologica. 2015; 100(8):e307-e310
Letter

2014

Beiträge in Fachzeitschriften

Chemotherapy-induced augmentation of T cells expressing inhibitory receptors is reversed by treatment with lenalidomide in chronic lymphocytic leukemia.
Gassner, FJ; Zaborsky, N; Neureiter, D; Huemer, M; Melchardt, T; Egle, A; Rebhandl, S; Catakovic, K; Hartmann, TN; Greil, R; Geisberger, R;
Haematologica. 2014; 99(5):67-69
Letter
AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.
Huemer, M; Rebhandl, S; Zaborsky, N; Gassner, FJ; Hainzl, S; Weiss, L; Hebenstreit, D; Greil, R; Geisberger, R;
Eur J Immunol. 2014; 44(12):3747-3757
Originalarbeiten (Zeitschrift)
APOBEC3 signature mutations in chronic lymphocytic leukemia.
Rebhandl, S; Huemer, M; Gassner, FJ; Zaborsky, N; Hebenstreit, D; Catakovic, K; Grössinger, E; Greil, R; Geisberger, R;
Leukemia. 2014; 28(9): 1929-1932.
Originalarbeiten (Zeitschrift)
Alternative splice variants of AID are not stoichiometrically present at the protein level in chronic lymphocytic leukemia.
Rebhandl, S; Huemer, M; Zaborsky, N; Gassner, FJ; Catakovic, K; Felder, TK; Greil, R; Geisberger, R;
Eur J Immunol. 2014; 44(7):2175-2187
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

The integrin VLA-4 shows impaired CXCL12-induced inside-out activation in trisomy12 harboring chronic lymphocytic leukemia (CLL) cells
Ganghammer, S; Hutterer, E; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, PW; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, TN
ONCOL RES TREAT. 2014; 37: 222-222.
Abstracts (Zeitschrift)
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner
Hutterer, E; Ganghammer, S; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, P; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, T
SCAND J IMMUNOL. 2014; 79(6): 468-468.
Abstracts (Zeitschrift)
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner
Hutterer, E; Ganghammer, S; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, P; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, T
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner. 2014; 79(6): 424-478.-Scandinavian Society for Immunology 42nd Annual Meeting; 11.-14.06.2014; Reykjavik.
Abstracts (Zeitschrift)

2013

Beiträge in Fachzeitschriften

A modified Phenol-chloroform extraction method for isolating circulating cell free DNA of tumor patients.
Hufnagl, C; Stöcher, M; Moik, M; Geisberger, R; Greil, R;
Journal of nucleic acids investigation. 2013; Vol 4, No 1 (2013): 1-3.
Originalarbeiten (Zeitschrift)

2012

Beiträge in Fachzeitschriften

Lysine residue at position 22 of the AID protein regulates its class switch activity.
Geisberger, R; Huemer, M; Gassner, FJ; Zaborsky, N; Egle, A; Greil, R;
PLoS One. 2012; 7(2):e30667
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

T Cell Exhaustion Contributes to Immune Evasion in Chronic Lymphocytic Leukaemia
Gassner, FJ; Zaborsky, N; Neureiter, D; Huemer, M; Egle, A; Hartmann, TN; Greil, R; Geisberger, R
BLOOD. 2012; 120(21):
Abstracts (Zeitschrift)

2011

Beiträge in Fachzeitschriften

Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Gassner, FJ; Weiss, L; Geisberger, R; Hofbauer, JP; Egle, A; Hartmann, TN; Greil, R; Tinhofer, I;
Cancer Immunol Immunother. 2011; 60(1):7-85
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

A Combination of Fludarabine/Rituximab with Escalating Doses of Lenalidomide in Previously Untreated Chronic Lymphocytic Leukemia (CLL): The REVLIRIT CLL5 AGMT Phase I/II Study, Clinical and Exploratory Analyses of Induction Results
Egle, A; Steurer, M; Gassner, F; Geisberger, R; Melchardt, T; Weiss, L; Fridrik, MA; Thaler, J; Lang, A; Greil, R
BLOOD. 2011; 118(21): 135-136.
Abstracts (Zeitschrift)

2009

Beiträge in Fachzeitschriften

The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence.
Geisberger, R; Rada, C; Neuberger, MS;
P NATL ACAD SCI USA. 2009; 106(16): 6736-6741.
Originalarbeiten (Zeitschrift)

2007

Beiträge in Fachzeitschriften

B- and T-cell-specific inactivation of thioredoxin reductase 2 does not impair lymphocyte development and maintenance.
Geisberger, R; Kiermayer, C; Hömig, C; Conrad, M; Schmidt, J; Zimber-Strobl, U; Brielmeier, M;
Biol Chem. 2007; 388(10):1083-1090
Originalarbeiten (Zeitschrift)

2006

Beiträge in Fachzeitschriften

Membrane IgM influences membrane IgD mediated antigen internalization in the B cell line Bcl1.
Geisberger, R; Königsberger, S; Achatz, G;
Immunol Lett. 2006; 102(2):169-176
Originalarbeiten (Zeitschrift)
The riddle of the dual expression of IgM and IgD.
Geisberger, R; Lamers, M; Achatz, G;
Immunology. 2006; 118(4):429-437
Übersichtsarbeiten
HS1-associated protein X-1 interacts with membrane-bound IgE: impact on receptor-mediated internalization.
Oberndorfer, I; Schmid, D; Geisberger, R; Achatz-Straussberger, G; Crameri, R; Lamers, M; Achatz, G;
J Immunol. 2006; 177(2):1139-1145
Originalarbeiten (Zeitschrift)

2005

Beiträge in Fachzeitschriften

Pharmacological and functional characterization of galanin-like peptide fragments as potent galanin receptor agonists.
Lang, R; Berger, A; Santic, R; Geisberger, R; Hermann, A; Herzog, H; Kofler, B;
NEUROPEPTIDES. 2005; 39(3): 179-184.
Originalarbeiten (Zeitschrift)

2003

Beiträge in Fachzeitschriften

Construction of a reporter mouse strain - A tool for studying IgE memory
Achatz-Straussberger, G; Geisberger, R; Infuhr, D; Oberndorfer, I; Fallon, P; Lamers, M; Achatz, G
. 2003; 189-191.
Übersichtsarbeiten
Construction of an sIgE:FLAG-mIgE:GFP reporter mouse strain.
Achatz-Straussberger, G; Geisberger, R; Oberndorfer, I; Inführ, D; Luger, E; Fallon, P; Lamers, M; Achatz, G;
INT ARCH ALLERGY IMM. 2003; 130(4): 280-287.
Originalarbeiten (Zeitschrift)
Isolation of a serine threonine kinase interacting with the cytoplasmic tail of mlgE
Geisberger, R; Achatz-Straussberger, G; Oberndorfer, I; Infuhr, D; Crameri, R; Achatz, G
. 2003; 177-181.
Originalarbeiten (Zeitschrift)
Models of signal transduction through the B-cell antigen receptor.
Geisberger, R; Crameri, R; Achatz, G;
IMMUNOLOGY. 2003; 110(4): 401-410.
Übersichtsarbeiten

2002

Beiträge in Fachzeitschriften

Phage display based cloning of proteins interacting with the cytoplasmic tail of membrane immunoglobulins.
Geisberger, R; Prlic, M; Achatz-Straussberger, G; Oberndorfer, I; Luger, E; Lamers, M; Crameri, R; Appenzeller, U; Wienands, J; Breitenbach, M; Ferreira, F; Achatz, G;
Dev Immunol. 2002; 9(3): 127-134.
Originalarbeiten (Zeitschrift)

2001

Beiträge in Fachzeitschriften

The IgE antigen receptor: a key regulator for the production of IgE antibodies.
Achatz, G; Luger, E; Geisberger, R; Achatz-Straussberger, G; Breitenbach, M; Lamers, M;
Int Arch Allergy Immunol. 2001; 124(1-3):31-34
Originalarbeiten (Zeitschrift)
Somatic diversity of the immunoglobulin repertoire is controlled in an isotype-specific manner.
Luger, E; Lamers, M; Achatz-Straussberger, G; Geisberger, R; Inführ, D; Breitenbach, M; Crameri, R; Achatz, G;
Eur J Immunol. 2001; 31(8):2319-2330
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

The IgE antigen-receptor: A key regulator for the quality of the IgE responses in vivo
Achatz, G; Luger, E; Achatz, G; Geisberger, R; Vogtenhuber, C; Infuhr, D; Lamers, M
J ALLERGY CLIN IMMUN. 2001; 107(2): S136-S136.
Abstracts (Zeitschrift)