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Forschungsdatenbank PMU-SQQUID

ASSLABER DANIELA
Universitätsklinik für Innere Medizin 3 - Hämatologie, internistische Onkologie, Hämostaseologie, Infektiologie, Rheumatologie und Onkologisches Zentrum

Publikationen | Forscherprofil

33 Publikationen

2019

Beiträge in Fachzeitschriften

BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation.
Asslaber, D; Wacht, N; Leisch, M; Qi, Y; Maeding, N; Hufnagl, C; Jansko, B; Zaborsky, N; Villunger, A; Hartmann, TN; Greil, R; Egle, A;
Clin Cancer Res. 2019; 25(6):1901-1912
Originalarbeiten (Zeitschrift)
Exome sequencing of the TCL1 mouse model for CLL reveals genetic heterogeneity and dynamics during disease development.
Zaborsky, N; Gassner, FJ; Höpner, JP; Schubert, M; Hebenstreit, D; Stark, R; Asslaber, D; Steiner, M; Geisberger, R; Greil, R; Egle, A;
Leukemia. 2019; 33(4):957-968
Originalarbeiten (Zeitschrift)

2018

Beiträge in Fachzeitschriften

Microenvironment-induced CD44v6 promotes early disease progression in chronic lymphocytic leukemia.
Gutjahr, JC; Szenes, E; Tschech, L; Asslaber, D; Schlederer, M; Roos, S; Yu, X; Girbl, T; Sternberg, C; Egle, A; Aberger, F; Alon, R; Kenner, L; Greil, R; Orian-Rousseau, V; Hartmann, TN;
Blood. 2018; 131(12): 1337-1349.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Exome sequencing of tumors from the TCL1 mouse model for CLL reveals genetic heterogeneity and dynamics during disease development
Egle, A; Gassner, FJ; Hopner, JP; Hebenstreit, D; Stark, R; Asslaber, D; Steiner, M; Geisberger, R; Greil, R; Zaborsky, N
ONCOL RES TREAT. 2018; 41: 31-31.
Abstracts (Zeitschrift)
Evaluation of circulating cell-free DNA as a molecular monitoring tool in patients with metastatic cancer
Hufnagl, C; Leisch, M; Weiss, L; Melchardt, T; Moik, M; Geisberger, R; Asslaber, D; Steininger, P; Meissnitzer, T; Neureiter, D; Greil, R; Egle, A
ONCOL RES TREAT. 2018; 41: 307-307.
Abstracts (Zeitschrift)

2017

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

CLL cells residing in spleen and bone marrow microenvironments differ in their CD44 variant usage for migration and proliferation
Gutjahr, JC; Szenes, E; Tschech, L; Schlederer, M; Roos, S; Asslaber, D; Girbl, T; Greil, R; Alon, R; Kenner, L; Orian-Rousseau, V; Hartmann, TN
Leukemia & Lymphoma. 2017; 58(sup1):1-240.-iwCLL; 12.05-15.05.2017; New York.
Abstracts (Zeitschrift)

2016

Beiträge in Fachzeitschriften

The AKT1 isoform plays a dominant role in the survival and chemoresistance of chronic lymphocytic leukaemia cells.
Hofbauer, SW; Krenn, PW; Piñόn Hofbauer, J; Pucher, S; Asslaber, D; Egle, A; Hartmann, TN; Greil, R;
Br J Haematol. 2016; 172(5):815-819
Letter
CD4+ T cells, but not non-classical monocytes, are dispensable for the development of chronic lymphocytic leukemia in the TCL1-tg murine model.
Kocher, T; Asslaber, D; Zaborsky, N; Flenady, S; Denk, U; Reinthaler, P; Ablinger, M; Geisberger, R; Bauer, JW; Seiffert, M; Hartmann, TN; Greil, R; Egle, A; Piñón Hofbauer, J;
Leukemia. 2016; 30(6):1409-1413
Letter
ILK Induction in Lymphoid Organs by a TNFα-NF-κB-Regulated Pathway Promotes the Development of Chronic Lymphocytic Leukemia.
Krenn, PW; Hofbauer, SW; Pucher, S; Hutterer, E; Hinterseer, E; Denk, U; Asslaber, D; Ganghammer, S; Sternberg, C; Neureiter, D; Aberger, F; Wickström, SA; Egle, A; Greil, R; Hartmann, TN;
Cancer Res. 2016; 76(8):218-296
Originalarbeiten (Zeitschrift)
CD1d expression on chronic lymphocytic leukemia B cells affects disease progression and induces T cell skewing in CD8 positive and CD4CD8 double negative T cells.
Zaborsky, N; Gassner, FJ; Asslaber, D; Reinthaler, P; Denk, U; Flenady, S; Hofbauer, JP; Danner, B; Rebhandl, S; Harrer, A; Geisberger, R; Greil, R; Egle, A;
Oncotarget. 2016; 7(31):4945-49469
Originalarbeiten (Zeitschrift)

2015

Beiträge in Fachzeitschriften

CXCL12-induced VLA-4 activation is impaired in trisomy 12 chronic lymphocytic leukemia cells: a role for CCL21.
Ganghammer, S; Hutterer, E; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, PW; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Kruschinski, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, TN;
Oncotarget. 2015; 6(14):12048-12060
Originalarbeiten (Zeitschrift)
CD18 (ITGB2) expression in chronic lymphocytic leukaemia is regulated by DNA methylation-dependent and -independent mechanisms.
Hutterer, E; Asslaber, D; Caldana, C; Krenn, PW; Zucchetto, A; Gattei, V; Greil, R; Hartmann, TN;
Br J Haematol. 2015; 169(2):286-289
Letter
B-cell receptor usage correlates with the sensitivity to CD40 stimulation and the occurrence of CD4+ T-cell clonality in chronic lymphocytic leukemia.
Zaborsky, N; Holler, C; Geisberger, R; Asslaber, D; Gassner, FJ; Egger, V; Piñón-Hofbauer, J; Kocher, T; Hartmann, TN; Greil, R; Egle, A;
Haematologica. 2015; 100(8):e307-e310
Letter

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Integrin-linked kinase is induced by TNF alpha- NF-kappa B signals and required for centrosome clustering and mitotic spindle organization during chronic lymphocytic leukemia cell cycle progression
Krenn, PW; Hofbauer, SW; Pucher, S; Hutterer, E; Hinterseer, E; Asslaber, D; Sternberg, C; Neureiter, D; Aberger, F; Wickstrom, SA; Greil, R; Hartmann, TN
LEUKEMIA LYMPHOMA. 2015; 56: 65-67.
Abstracts (Zeitschrift)

2014

Beiträge in Fachzeitschriften

Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade.
Grössinger, EM; Weiss, L; Zierler, S; Rebhandl, S; Krenn, PW; Hinterseer, E; Schmölzer, J; Asslaber, D; Hainzl, S; Neureiter, D; Egle, A; Piñón-Hofbauer, J; Hartmann, TN; Greil, R; Kerschbaum, HH;
Leukemia. 2014; 28(4):954-958
Letter
Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells.
Hofbauer, SW; Krenn, PW; Ganghammer, S; Asslaber, D; Pichler, U; Oberascher, K; Henschler, R; Wallner, M; Kerschbaum, H; Greil, R; Hartmann, TN;
Blood. 2014; 123(14):2181-2188
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

The integrin VLA-4 shows impaired CXCL12-induced inside-out activation in trisomy12 harboring chronic lymphocytic leukemia (CLL) cells
Ganghammer, S; Hutterer, E; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, PW; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, TN
ONCOL RES TREAT. 2014; 37: 222-222.
Abstracts (Zeitschrift)
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner
Hutterer, E; Ganghammer, S; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, P; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, T
SCAND J IMMUNOL. 2014; 79(6): 468-468.
Abstracts (Zeitschrift)
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner
Hutterer, E; Ganghammer, S; Hinterseer, E; Brachtl, G; Asslaber, D; Krenn, P; Girbl, T; Berghammer, P; Geisberger, R; Egle, A; Zucchetto, A; Gattei, V; Chigaev, A; Greil, R; Hartmann, T
Chronic Lymphocytic Leukaemia Cells with Trisomy 12 Home to the Bone Marrow in a CXCR4-Independent Manner. 2014; 79(6): 424-478.-Scandinavian Society for Immunology 42nd Annual Meeting; 11.-14.06.2014; Reykjavik.
Abstracts (Zeitschrift)

2013

Beiträge in Fachzeitschriften

Mimicking the microenvironment in chronic lymphocytic leukaemia - where does the journey go?
Asslaber, D; Grössinger, EM; Girbl, T; Hofbauer, SW; Egle, A; Weiss, L; Greil, R; Hartmann, TN;
Br J Haematol. 2013; 160(5):711-714
Letter
Bid-ding for mercy: twisted killer in action.
Egle, A; Asslaber, D; Villunger, A; Pinon-Hofbauer, J;
Cell Death Differ. 2013; 20(7):847-849
Editorials
CD40-mediated activation of chronic lymphocytic leukemia cells promotes their CD44-dependent adhesion to hyaluronan and restricts CCL21-induced motility.
Girbl, T; Hinterseer, E; Grössinger, EM; Asslaber, D; Oberascher, K; Weiss, L; Hauser-Kronberger, C; Neureiter, D; Kerschbaum, H; Naor, D; Alon, R; Greil, R; Hartmann, TN;
Cancer Res. 2013; 73(2): 561-570.
Originalarbeiten (Zeitschrift)

2011

Beiträge in Fachzeitschriften

Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.
Hofbauer, JP; Heyder, C; Denk, U; Kocher, T; Holler, C; Trapin, D; Asslaber, D; Tinhofer, I; Greil, R; Egle, A;
Leukemia. 2011; 25(9): 1452-1458.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

CLL CELLS INDUCE CLONAL T CELL SKEWING AND SUBSETSHIFTING IN THE MURINE TCL1 TRANSGENIC CHRONIC LYMPHOCYTIC LEUKEMIA MODEL
Egle, A; Pinon-Hofbauer, J; Heyder, C; Denk, U; Kocher, T; Holler, C; Trapin, D; Asslaber, D; Tinhofer, I; Greil, R
ANN ONCOL. 2011; 22: 144-144.
Abstracts (Zeitschrift)
CD44-hyaluronan interactions in the pathophysiology of chronic lymphocytic leukemia - regulation by cell activation
Girbl, T; Asslaber, D; Brachtl, G; Denk, U; Weiss, L; Naor, D; Greil, R; Hartmann, TN
ONKOLOGIE. 2011; 34: 140-140.
Abstracts (Zeitschrift)
Clonal Diversity of the T Cell Repertoire Predicts Disease Progression in Chronic Lymphocytic Leukaemia
Holler, C; Zaborsky, N; Hofbauer, JP; Kocher, T; Trapin, D; Asslaber, D; Greil, R; Egle, A
BLOOD. 2011; 118(21): 365-365.
Abstracts (Zeitschrift)

2010

Beiträge in Fachzeitschriften

MicroRNAs as biomarkers for the diagnosis and prognosis of human cancer.
Asslaber, D; Pinon Hofbauer, J; Greil, R; Egle, A
Journal of nucleic acids investigation. 2010; Dec 1, 1(1): 76-80.
Originalarbeiten (Zeitschrift)
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Asslaber, D; Piñón, JD; Seyfried, I; Desch, P; Stöcher, M; Tinhofer, I; Egle, A; Merkel, O; Greil, R;
Blood. 2010; 115(21):4191-4197
Originalarbeiten (Zeitschrift)
Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
Desch, P; Asslaber, D; Kern, D; Schnidar, H; Mangelberger, D; Alinger, B; Stoecher, M; Hofbauer, SW; Neureiter, D; Tinhofer, I; Aberger, F; Hartmann, TN; Greil, R;
Oncogene. 2010; 29(35): 488-495.
Originalarbeiten (Zeitschrift)
Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.
Merkel, O; Asslaber, D; Piñón, JD; Egle, A; Greil, R;
Cell Cycle. 2010; 9(14):2764-2768
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Deletion of Puma and p21(Waf1) In Mice Deactivates p53-Induced Cell Death and Cell Cycle Arrest, but Protects Mice From Irradiation-Induced Lymphomagenesis by a Mechanism Involving Hemopoietic Stem Cell Quiescence
Hofbauer, JP; Holler, C; Denk, U; Asslaber, D; Fastner, G; Labi, V; Villunger, A; Greil, R; Egle, A
BLOOD. 2010; 116(21): 45-46.
Abstracts (Zeitschrift)
Antiapoptotic effects of p21 in arsenic trioxide induced apoptosis in CLL
Sifft, E; Asslaber, D; Schweiggl, S; Hamacher, F; Greil, R; Merkel, O
ONKOLOGIE. 2010; 33: 185-185.
Abstracts (Zeitschrift)

2008

Beiträge in Fachzeitschriften

Arsenic trioxide induces apoptosis preferentially in B-CLL cells of patients with unfavourable prognostic factors including del17p13.
Merkel, O; Heyder, C; Asslaber, D; Hamacher, F; Tinhofer, I; Holler, C; Stöcher, M; Prokesch, A; Papak, C; Scheideler, M; Trajanoski, Z; Greil, R;
J Mol Med (Berl). 2008; 86(5):541-552
Originalarbeiten (Zeitschrift)