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Forschungsdatenbank PMU-SQQUID

Klinikum Nürnberg Medical School GmbH

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41 Publikationen


Beiträge in Fachzeitschriften

A tetracycline-inducible integrative expression system for Streptococcus pneumoniae
Meiers, M; Laux, A; Eichinger, D; Sexauer, A; Marx, P; Bertram, R; Bruckner, R
FEMS MICROBIOL LETT. 2017; 364(5): fnx044
Originalarbeiten (Zeitschrift)
TetR-dependent gene regulation in intracellular Listeria monocytogenes demonstrates the spatiotemporal surface distribution of ActA.
Schmitter, S; Fieseler, L; Klumpp, J; Bertram, R; Loessner, MJ
MOL MICROBIOL. 2017; 105(3): 413-425.
Originalarbeiten (Zeitschrift)
Identification of Genes Controlled by the Essential YycFG Two-Component System Reveals a Role for Biofilm Modulation in Staphylococcus epidermidis.
Xu, T; Wu, Y; Lin, ZW; Bertram, R; Gotz, F; Zhang, Y; Qu, D
FRONT MICROBIOL. 2017; 8: 724
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

BACTERIAL PHYSIOLOGY Persisters run out of fuel
Bertram, R
NAT MICROBIOL. 2016; 1(5): 16060
Complementation Plasmids, Inducible Gene-Expression Systems, and Reporters for Staphylococci.
Bertram, R;
Methods Mol Biol. 2016; 1373:25-32
Originalarbeiten (Zeitschrift)
Daptomycin Tolerance in the Staphylococcus aureus pitA6 Mutant Is Due to Upregulation of the dlt Operon.
Mechler, L; Bonetti, EJ; Reichert, S; Flötenmeyer, M; Schrenzel, J; Bertram, R; François, P; Götz, F;
Antimicrob Agents Chemother. 2016; 60(5): 2684-2691.
Originalarbeiten (Zeitschrift)
Glucose Augments Killing Efficiency of Daptomycin Challenged Staphylococcus aureus Persisters.
Prax, M; Mechler, L; Weidenmaier, C; Bertram, R
PLoS One. 2016; 11(3):e0150907
Originalarbeiten (Zeitschrift)
Toxin-Antitoxin Systems of Staphylococcus aureus
Schuster, CF; Bertram, R
TOXINS. 2016; 8(5): 140


Beiträge in Fachzeitschriften

A novel point mutation promotes growth phase-dependent daptomycin tolerance in Staphylococcus aureus.
Mechler, L; Herbig, A; Paprotka, K; Fraunholz, M; Nieselt, K; Bertram, R;
Antimicrob Agents Chemother. 2015; 59(9): 5366-5376.
Originalarbeiten (Zeitschrift)
The MazEF Toxin-Antitoxin System Alters the beta-Lactam Susceptibility of Staphylococcus aureus.
Schuster, CF; Mechler, L; Nolle, N; Krismer, B; Zelder, ME; Gotz, F; Bertram, R;
PLOS ONE. 2015; 10(5):
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

Post-transcriptional regulation of gene expression in bacterial pathogens by toxin-antitoxin systems.
Bertram, R; Schuster, CF;
Front Cell Infect Microbiol. 2014; 4: 6
Metabolic and transcriptional activities of Staphylococcus aureus challenged with high-doses of daptomycin.
Lechner, S; Prax, M; Lange, B; Huber, C; Eisenreich, W; Herbig, A; Nieselt, K; Bertram, R;
Int J Med Microbiol. 2014; 304(8): 931-940.
Originalarbeiten (Zeitschrift)
Metabolic aspects of bacterial persisters.
Prax, M; Bertram, R;
Front Cell Infect Microbiol. 2014; 4: 148
Fluorescence based primer extension technique to determine transcriptional starting points and cleavage sites of RNases in vivo.
Schuster, CF; Bertram, R;
J Vis Exp. 2014; (92): e52134
Originalarbeiten (Zeitschrift)
Characterization of multi-drug tolerant persister cells in Streptococcus suis.
Willenborg, J; Willms, D; Bertram, R; Goethe, R; Valentin-Weigand, P;
BMC Microbiol. 2014; 14: 120
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

Catabolite control protein E (CcpE) is a LysR-type transcriptional regulator of tricarboxylic acid cycle activity in Staphylococcus aureus.
Hartmann, T; Zhang, B; Baronian, G; Schulthess, B; Homerova, D; Grubmüller, S; Kutzner, E; Gaupp, R; Bertram, R; Powers, R; Eisenreich, W; Kormanec, J; Herrmann, M; Molle, V; Somerville, GA; Bischoff, M;
J Biol Chem. 2013; 288(50): 36116-36128.
Originalarbeiten (Zeitschrift)
Two paralogous yefM-yoeB loci from Staphylococcus equorum encode functional toxin-antitoxin systems.
Nolle, N; Schuster, CF; Bertram, R;
Microbiology. 2013; 159(Pt 8): 157-185.
Originalarbeiten (Zeitschrift)
An update on the molecular genetics toolbox for staphylococci.
Prax, M; Lee, CY; Bertram, R;
Microbiology. 2013; 159(Pt 3): 421-435.
Toxin-antitoxin systems are ubiquitous and versatile modulators of prokaryotic cell fate.
Schuster, CF; Bertram, R;
FEMS Microbiol Lett. 2013; 340(2): 73-85.
Characterization of a mazEF toxin-antitoxin homologue from Staphylococcus equorum.
Schuster, CF; Park, JH; Prax, M; Herbig, A; Nieselt, K; Rosenstein, R; Inouye, M; Bertram, R;
J Bacteriol. 2013; 195(1): 11-25.
Originalarbeiten (Zeitschrift)
The mevalonate auxotrophic mutant of Staphylococcus aureus can adapt to mevalonate depletion.
Yu, W; Leibig, M; Schäfer, T; Bertram, R; Ohlsen, K; Götz, F;
Antimicrob Agents Chemother. 2013; 57(11): 5710-5713.
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

Intracellular monitoring of target protein production in Staphylococcus aureus by peptide tag-induced reporter fluorescence.
Gauger, T; Weihs, F; Mayer, S; Krismer, B; Liese, J; Kull, M; Bertram, R;
Microb Biotechnol. 2012; 5(1):129-134
Originalarbeiten (Zeitschrift)
Staphylococcus aureus persisters tolerant to bactericidal antibiotics.
Lechner, S; Lewis, K; Bertram, R;
J Mol Microbiol Biotechnol. 2012; 22(4): 235-244.
Originalarbeiten (Zeitschrift)
Interplay between population dynamics and drug tolerance of Staphylococcus aureus persister cells.
Lechner, S; Patra, P; Klumpp, S; Bertram, R;
J Mol Microbiol Biotechnol. 2012; 22(6): 38-91.
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

Regulon of the N-acetylglucosamine utilization regulator NagR in Bacillus subtilis.
Bertram, R; Rigali, S; Wood, N; Lulko, AT; Kuipers, OP; Titgemeyer, F;
J Bacteriol. 2011; 193(14): 3525-3536.
Originalarbeiten (Zeitschrift)
Vectors for improved Tet repressor-dependent gradual gene induction or silencing in Staphylococcus aureus.
Helle, L; Kull, M; Mayer, S; Marincola, G; Zelder, ME; Goerke, C; Wolz, C; Bertram, R;
Microbiology. 2011; 157(Pt 12): 3314-3323.
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

New architectures for Tet-on and Tet-off regulation in Staphylococcus aureus.
Stary, E; Gaupp, R; Lechner, S; Leibig, M; Tichy, E; Kolb, M; Bertram, R;
Appl Environ Microbiol. 2010; 76(3): 680-687.
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

In vivo activation of tetracycline repressor by Cre/lox-mediated gene assembly.
Bertram, R; Kolb, M; Hillen, W;
J Mol Microbiol Biotechnol. 2009; 17(3): 136-145.
Originalarbeiten (Zeitschrift)
Small-colony variant selection as a survival strategy for Staphylococcus aureus in the presence of Pseudomonas aeruginosa.
Biswas, L; Biswas, R; Schlag, M; Bertram, R; Götz, F;
Appl Environ Microbiol. 2009; 75(21): 6910-6912.
Originalarbeiten (Zeitschrift)
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of YvoA from Bacillus subtilis.
Resch, M; Roth, HM; Kottmair, M; Sevvana, M; Bertram, R; Titgemeyer, F; Muller, YA;
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009; 65(Pt 4):410-414
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

The application of Tet repressor in prokaryotic gene regulation and expression.
Bertram, R; Hillen, W;
Microb Biotechnol. 2008; 1(1): 2-16.
Marker removal in staphylococci via Cre recombinase and different lox sites.
Leibig, M; Krismer, B; Kolb, M; Friede, A; Götz, F; Bertram, R;
Appl Environ Microbiol. 2008; 74(5):1316-1323
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

Regulated expression of HPrK/P does not affect carbon catabolite repression of the xyn operon and of rocG in Bacillus subtilis.
Bertram, R; Wünsche, A; Sprehe, M; Hillen, W;
FEMS Microbiol Lett. 2006; 259(1):147-152
Originalarbeiten (Zeitschrift)
Induction of single chain tetracycline repressor requires the binding of two inducers.
Kamionka, A; Majewski, M; Roth, K; Bertram, R; Kraft, C; Hillen, W;
Nucleic Acids Res. 2006; 34(14):3834-3841
Originalarbeiten (Zeitschrift)
Generating tetracycline-inducible auxotrophy in Escherichia coli and Salmonella enterica serovar Typhimurium by using an insertion element and a hyperactive transposase.
Köstner, M; Schmidt, B; Bertram, R; Hillen, W;
Appl Environ Microbiol. 2006; 72(7):4717-4725
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

Integrative elements for Bacillus subtilis yielding tetracycline-dependent growth phenotypes.
Bertram, R; Köstner, M; Müller, J; Vazquez Ramos, J; Hillen, W;
Nucleic Acids Res. 2005; 33(18):e153
Originalarbeiten (Zeitschrift)
Tet repressor mutants with altered effector binding and allostery.
Henssler, EM; Bertram, R; Wisshak, S; Hillen, W;
FEBS J. 2005; 272(17):4487-4496
Originalarbeiten (Zeitschrift)
Tetracycline-dependent conditional gene knockout in Bacillus subtilis.
Kamionka, A; Bertram, R; Hillen, W;
Appl Environ Microbiol. 2005; 71(2):728-733
Originalarbeiten (Zeitschrift)


Beiträge in Fachzeitschriften

Phenotypes of combined tet repressor mutants for effector and operator recognition and allostery.
Bertram, R; Kraft, C; Wisshak, S; Mueller, J; Scholz, O; Hillen, W;
J Mol Microbiol Biotechnol. 2004; 8(2):104-110
Originalarbeiten (Zeitschrift)
In silico and transcriptional analysis of carbohydrate uptake systems of Streptomyces coelicolor A3(2).
Bertram, R; Schlicht, M; Mahr, K; Nothaft, H; Saier, MH; Titgemeyer, F;
J Bacteriol. 2004; 186(5):1362-1373
Originalarbeiten (Zeitschrift)
Activity reversal of Tet repressor caused by single amino acid exchanges.
Scholz, O; Henssler, EM; Bail, J; Schubert, P; Bogdanska-Urbaniak, J; Sopp, S; Reich, M; Wisshak, S; Köstner, M; Bertram, R; Hillen, W;
Mol Microbiol. 2004; 53(3):777-789
Originalarbeiten (Zeitschrift)