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Forschungsdatenbank PMU-SQQUID

AIGNER LUDWIG
Universitätsinstitut für Molekulare Regenerative Medizin
Zentrum für Querschnitt- und Geweberegeneration Salzburg

Publikationen | Forscherprofil

181 Publikationen

2018

Beiträge in Fachzeitschriften

Motor deficits following dorsal corticospinal tract transection in rats: voluntary versus skilled locomotion readouts.
Bieler, L; Grassner, L; Zaunmair, P; Kreutzer, C; Lampe, L; Trinka, E; Marschallinger, J; Aigner, L; Couillard-Despres, S;
Heliyon. 2018; 4(2):e00540
Originalarbeiten (Zeitschrift)
A new technique for minimal invasive complete spinal cord injury in minipigs.
Foditsch, EE; Miclaus, G; Patras, I; Hutu, I; Roider, K; Bauer, S; Janetschek, G; Aigner, L; Zimmermann, R;
Acta Neurochir (Wien). 2018; 160(3):459-465
Originalarbeiten (Zeitschrift)
Cystometric and External Urethral Sphincter Measurements in Awake Rats with Implanted Catheter and Electrodes Allowing for Repeated Measurements
Foditsch, EE; Roider, K; Sartori, AM; Kessler, TM; Kayastha, SR; Aigner, L; Schneider, MP
JOVE-J VIS EXP. 2018; (131): e56506
Originalarbeiten (Zeitschrift)
Reactive Neuroblastosis in Huntingtonxxxs Disease: A Putative Therapeutic Target for Striatal Regeneration in the Adult Brain
Kandasamy, M; Aigner, L
FRONT CELL NEUROSCI. 2018; 12: 37
Originalarbeiten (Zeitschrift)
Human Adult Neurogenesis: Evidence and Remaining Questions
Kempermann, G; Gage, FH; Aigner, L; Song, HJ; Curtis, MA; Thuret, S; Kuhn, HG; Jessberger, S; Frankland, PW; Cameron, HA; Gould, E; Hen, R; Abrous, DN; Toni, N; Schinder, AF; Zhao, XY; Lucassen, PJ; Frisen, J
CELL STEM CELL. 2018; 23(1): 25-30.
Übersichtsarbeiten
Cellular Plasticity in the Adult Murine Piriform Cortex: Continuous Maturation of Dormant Precursors Into Excitatory Neurons
Rotheneichner, P; Belles, M; Benedetti, B; Konig, R; Dannehl, D; Kreutzer, C; Zaunmair, P; Engelhardt, M; Aigner, L; Nacher, J; Couillard-Despres, S
CEREB CORTEX. 2018; 28(7): 2610-2621.
Originalarbeiten (Zeitschrift)
Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-β plaques: A potential role in shaping plaque pathology?
Unger, MS; Marschallinger, J; Kaindl, J; Klein, B; Johnson, M; Khundakar, AA; Roßner, S; Heneka, MT; Couillard-Despres, S; Rockenstein, E; Masliah, E; Attems, J; Aigner, L;
Alzheimers Dement. 2018;
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Benedetti, B; König, R; Dannehl, D; Kreutzer, C; Belles, M; Ritter, M; Weiger, TM; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S;
Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex. 2018; -Paracelsus Science Get Together 2018; 29.06.2018; Salzburg.
Abstracts (Zeitschrift)

Nichtpublizierte (nicht zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Physiological maturation and network integration of non-proliferative neuronal precursors in the adult murine piriform cortex
Benedetti, B; König, R; Dannehl, D; Kreutzer, C; Belles, M; Ritter, M; Weiger, TM; Nacher, J; Engelhardt, M; Aigner, L; Couillard-Després, S;
2018; -11th FENS, Forum of Neuroscience; 07-11.07.2018; Berlin.
ENDF1 – a prenylated flavonoid- neutralizes inhibitory effect of ECM proteins on axonal regrowth
Bieler, L; Vogl, M; Kirchinger, M; Urmann, C; Riepl, H; Aigner, L; Couillard-Després, S
Paracelsus Science get to together; 29.06.2018; Paracelsus Medizinische Privatuniversität Salzburg. 2018.
ENDF1 – a prenylated flavonoid- neutralizes inhibitory effect of ECM proteins on axonal regrowth
Bieler, L; Vogl, M; Kirchinger, M; Urmann, C; Riepl, H; Aigner, L; Couillard-Després, S
FENS Forum 2018; 07.-11.07.2018; Berlin. 2018.

2017

Beiträge in Fachzeitschriften

Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis.
Adamczak, J; Aswendt, M; Kreutzer, C; Rotheneichner, P; Riou, A; Selt, M; Beyrau, A; Uhlenküken, U; Diedenhofen, M; Nelles, M; Aigner, L; Couillard-Despres, S; Hoehn, M;
Neurobiol Dis. 2017; 99: 47-57.
Originalarbeiten (Zeitschrift)
The Austrian Spinal Cord Injury Study: a registry for patients living with a traumatic spinal cord injury.
Aschauer-Wallner, S; Mattiassich, G; Aigner, L; Resch, H;
Spinal Cord Ser Cases. 2017; 3: 17076
Originalarbeiten (Zeitschrift)
Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination.
De La Fuente, AG; Lange, S; Silva, ME; Gonzalez, GA; Tempfer, H; van Wijngaarden, P; Zhao, C; Di Canio, L; Trost, A; Bieler, L; Zaunmair, P; Rotheneichner, P; O"Sullivan, A; Couillard-Despres, S; Errea, O; Mäe, MA; Andrae, J; He, L; Keller, A; Bátiz, LF; Betsholtz, C; Aigner, L; Franklin, RJM; Rivera, FJ;
Cell Rep. 2017; 20(8): 1755-1764.
Originalarbeiten (Zeitschrift)
SMAD7 deficiency stimulates Müller progenitor cell proliferation during the development of the mammalian retina.
Kugler, M; Schlecht, A; Fuchshofer, R; Schmitt, SI; Kleiter, I; Aigner, L; Tamm, ER; Braunger, BM
HISTOCHEM CELL BIOL. 2017; 148(1): 21-32.
Originalarbeiten (Zeitschrift)
The TgF-beta system as a Potential Pathogenic Player in Disease Modulation of amyotrophic lateral sclerosis
Peters, S; Zitzelsperger, E; Kuespert, S; Iberl, S; Heydn, R; Johannesen, S; Petri, S; Aigner, L; Thal, DR; Hermann, A; Weishaupt, JH; Bruun, TH; Bogdahn, U
FRONT NEUROL. 2017; 8: 669
Originalarbeiten (Zeitschrift)
Editorial: The Vascular Niche in Tissue Repair: A Therapeutic Target for Regeneration.
Rivera, FJ; Silva, ME; Aigner, L;
Front Cell Dev Biol. 2017; 5: 88
Editorials
Tamoxifen Activation of Cre-Recombinase Has No Persisting Effects on Adult Neurogenesis or Learning and Anxiety.
Rotheneichner, P; Romanelli, P; Bieler, L; Pagitsch, S; Zaunmair, P; Kreutzer, C; König, R; Marschallinger, J; Aigner, L; Couillard-Després, S;
Front Neurosci. 2017; 11: 27
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Pericytes promote the generation of oligodendrocytes during remyelination
Guzman, A; Lange, S; Silva, ME; Gonzalez, GA; Tempfer, H; van Wijngaarden, P; Zhao, C; Rotheneichner, P; Trost, A; OxxxSullivan, A; Couillard-Despres, S; Bieler, L; Errea, O; Mae, MA; Andrae, J; He, L; Keller, A; Betsholtz, C; Aigner, L; Franklin, RJM; Rivera, FJ
GLIA. 2017; 65: E541-E542.
Abstracts (Zeitschrift)
Neuroprotective activity of mesenchymal stromal cells and their secreted vesicles in a spinal cord contusion rat model
Romanelli, P; Bieler, L; Scharler, C; Pachler, K; Kreutzer, C; Zaunmair, P; Aigner, L; Rivera, FJ; Rohde, E; Benedetti, B; Gimona, M; Strunk, D; Couillard-Despres, S
TRANSFUS MED HEMOTH. 2017; 44: 76-76.
Abstracts (Zeitschrift)

Nichtpublizierte (nicht zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

A non-surgical technique for minimally-invasive complete spinal cord lesion in minipigs
Aigner, L
15th ANA Meeting; 24.-26.09.2017; Klosterneuburg. 2017.
Repurposing of the anti-asthmatic drug Montelukast for the Treatment of Alzheimer's Disease
Aigner, L
AAIC 2017, Alzheimer’s Association International Conference; 16.-20.07.2017; London. 2017.
Systemic rejuvenation: From blood to molecular therapies
Aigner, L
Integrated Continuous Biomanufacturing III; 17.-19.09.2017; Cascais. 2017.
The Anti-Asthmatic Drug Montelukast Alters Microglia Phenotype and Synucleopathy, and restores Learning and Memory in an Animal Model of Lewy Body Dementia.
Aigner, L; Marschallinger, J; Altendorfer, B; Pillichshammer, N; Garnweidner, J; Rockenstein, E; Masliah, E;
ADPD2017, 13th International Conference on Alzheimer’s and Parkinson’s Disease, Vienna; 28.03.-03.04.2017; Wien. 2017.
Repurposing of the Anti-Asthmatic Drug Montelukast for the Treatment of Alzheimer’s Disease
Aigner, L; Marschalllinger, J; Obeid, R; Conway, J; Zerbe, H; Paiement, N;
ADPD2017, 13th International Conference on Alzheimer’s and Parkinson’s Disease, Vienna; 28.03.-02.04.2017; Wien. 2017.

2016

Beiträge in Fachzeitschriften

Nontraumatic spinal cord injury at the neurological intensive care unit: spectrum, causes of admission and predictors of mortality.
Grassner, L; Marschallinger, J; Dünser, MW; Novak, HF; Zerbs, A; Aigner, L; Trinka, E; Sellner, J;
Ther Adv Neurol Disord. 2016; 9(2):85-94
Originalarbeiten (Zeitschrift)
Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus.
Klein, B; Mrowetz, H; Thalhamer, J; Scheiblhofer, S; Weiss, R; Aigner, L;
Front Cell Neurosci. 2016; 10: 169
Originalarbeiten (Zeitschrift)
Distribution and fate of DCX/PSA-NCAM expressing cells in the adult mammalian cortex: A local reservoir for adult cortical neuroplasticity?
König, R; Benedetti, B; Rotheneichner, P; O'Sullivan, A; Kreutzer, C; Belles, M; Nacher, J; Weiger, TM; Aigner, L; Couillard-Despres, S
Frontiers in Biology. 2016; 11(3): 193-213.
Originalarbeiten (Zeitschrift)
Human Cerebrospinal Fluid Promotes Neuronal Viability and Activity of Hippocampal Neuronal Circuits In Vitro
Perez-Alcazar, M; Culley, G; Lyckenvik, T; Mobarrez, K; Bjorefeldt, A; Wasling, P; Seth, H; Asztely, F; Harrer, A; Iglseder, B; Aigner, L; Hanse, E; Illes, S
FRONT CELL NEUROSCI. 2016; 10:
Originalarbeiten (Zeitschrift)
Beyond Clotting: A Role of Platelets in CNS Repair?
Rivera, FJ; Kazanis, I; Ghevaert, C; Aigner, L
FRONT CELL NEUROSCI. 2016; 9:
Editorials
Brain and Retinal Pericytes: Origin, Function and Role.
Trost, A; Lange, S; Schroedl, F; Bruckner, D; Motloch, KA; Bogner, B; Kaser-Eichberger, A; Strohmaier, C; Runge, C; Aigner, L; Rivera, FJ; Reitsamer, HA;
Front Cell Neurosci. 2016; 10: 20
Übersichtsarbeiten
Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimerxxxs Disease
Unger, MS; Marschallinger, J; Kaindl, J; Hofling, C; Rossner, S; Heneka, MT; Van der Linden, A; Aigner, L
MOL NEUROBIOL. 2016; 53(8): 5796-5806.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Expression of the precursor marker Sox2 in the myenteric plexus in the caecum of postnatal and adult mouse
Grundmann, D; Loris, E; Marx, L; Wilms, E; Aigner, L; Couillard-Despres, S; Reinhardt, C; Schafer, KH
NEUROGASTROENT MOTIL. 2016; 28: 51-51.
Abstracts (Zeitschrift)

Nichtpublizierte (nicht zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Structural and Functional Rejuvenation of the Aged Brain
Aigner, L;
University of Zagreb; 03.-05.02.2016; Zagreb. 2016.
Brain Rejuvenation - A Therapeutic Concept for CNS Diseases?
Aigner, L;
Eingeladener Vortrag; 06.04.2016; Universitätsklinikum Heidelberg Klinik für Paraplegiologie Experimentelle Neurorehabilitation Heidelberg . 2016.

Originalbeiträge in Sammelwerk (Buchbeitrag)

Chapter 7 – Aging
König, R; Rotheneichner, P; Marschallinger, J; Aigner, L; Couillard-Despres, S;
In: Canales, JJ editors(s). Adult Neurogenesis in the Hippocampus. Academic Press; p. 145-176. (ISBN: 9780128019771)

2015

Beiträge in Fachzeitschriften

[254-POS]: Changes in maternal cognition after previous pregnancies with preeclampsia.
Hillerer, KM; Jacobs, VR; Aigner, L; Fischer, T;
Pregnancy Hypertens. 2015; 5(1): 128
Abstracts (Zeitschrift)
Reduction in subventricular zone-derived olfactory bulb neurogenesis in a rat model of Huntington"s disease is accompanied by striatal invasion of neuroblasts.
Kandasamy, M; Rosskopf, M; Wagner, K; Klein, B; Couillard-Despres, S; Reitsamer, HA; Stephan, M; Nguyen, HP; Riess, O; Bogdahn, U; Winkler, J; von Horsten, S; Aigner, L
PLoS One. 2015; 10(2):e0116069
Originalarbeiten (Zeitschrift)
Lesion-induced accumulation of platelets promotes survival of adult neural stem / progenitor cells.
Kazanis, I; Feichtner, M; Lange, S; Rotheneichner, P; Hainzl, S; Öller, M; Schallmoser, K; Rohde, E; Reitsamer, HA; Couillard-Despres, S; Bauer, HC; Franklin, RJ; Aigner, L; Rivera, FJ;
Exp Neurol. 2015; 269: 75-89.
Originalarbeiten (Zeitschrift)
Heterozygous modulation of TGF-β signaling does not influence Müller glia cell reactivity or proliferation following NMDA-induced damage.
Kugler, M; Schlecht, A; Fuchshofer, R; Kleiter, I; Aigner, L; Tamm, ER; Braunger, BM
HISTOCHEM CELL BIOL. 2015; 144(5): 443-455.
Originalarbeiten (Zeitschrift)
Impaired TGF-beta induced growth inhibition contributes to the increased proliferation rate of neural stem cells harboring mutant p53
Kumar, P; Naumann, U; Aigner, L; Wischhusen, J; Beier, CP; Beier, D
AM J CANCER RES. 2015; 5(11): 3436-3445.
Originalarbeiten (Zeitschrift)
Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.
Lener, T; Gimona, M; Aigner, L; Börger, V; Buzas, E; Camussi, G; Chaput, N; Chatterjee, D; Court, FA; Del Portillo, HA; O"Driscoll, L; Fais, S; Falcon-Perez, JM; Felderhoff-Mueser, U; Fraile, L; Gho, YS; Görgens, A; Gupta, RC; Hendrix, A; Hermann, DM; Hill, AF; Hochberg, F; Horn, PA; de Kleijn, D; Kordelas, L; Kramer, BW; Krämer-Albers, EM; Laner-Plamberger, S; Laitinen, S; Leonardi, T; Lorenowicz, MJ; Lim, SK; Lötvall, J; Maguire, CA; Marcilla, A; Nazarenko, I; Ochiya, T; Patel, T; Pedersen, S; Pocsfalvi, G; Pluchino, S; Quesenberry, P; Reischl, IG; Rivera, FJ; Sanzenbacher, R; Schallmoser, K; Slaper-Cortenbach, I; Strunk, D; Tonn, T; Vader, P; van Balkom, BW; Wauben, M; Andaloussi, SE; Théry, C; Rohde, E; Giebel, B;
J Extracell Vesicles. 2015; 4: 30087
Originalarbeiten (Zeitschrift)
The L-type calcium channel Cav1.3 is required for proper hippocampal neurogenesis and cognitive functions.
Marschallinger, J; Sah, A; Schmuckermair, C; Unger, M; Rotheneichner, P; Kharitonova, M; Waclawiczek, A; Gerner, P; Jaksch-Bogensperger, H; Berger, S; Striessnig, J; Singewald, N; Couillard-Despres, S; Aigner, L;
Cell Calcium. 2015; 58(6): 606-616.
Originalarbeiten (Zeitschrift)
Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.
Marschallinger, J; Schäffner, I; Klein, B; Gelfert, R; Rivera, FJ; Illes, S; Grassner, L; Janssen, M; Rotheneichner, P; Schmuckermair, C; Coras, R; Boccazzi, M; Chishty, M; Lagler, FB; Renic, M; Bauer, HC; Singewald, N; Blümcke, I; Bogdahn, U; Couillard-Despres, S; Lie, DC; Abbracchio, MP; Aigner, L;
Nat Commun. 2015; 6: 8466
Originalarbeiten (Zeitschrift)
Time-dependent retinal ganglion cell loss, microglial activation and blood-retina-barrier tightness in an acute model of ocular hypertension.
Trost, A; Motloch, K; Bruckner, D; Schroedl, F; Bogner, B; Kaser-Eichberger, A; Runge, C; Strohmaier, C; Klein, B; Aigner, L; Reitsamer, HA;
Exp Eye Res. 2015; 136:59-71
Originalarbeiten (Zeitschrift)
Neurodifferentiating potential of 8-prenylnaringenin and related compounds in neural precursor cells and correlation with estrogen-like activity.
Urmann, C; Oberbauer, E; Couillard-Després, S; Aigner, L; Riepl, H;
Planta Med. 2015; 81(4):305-311
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Structural modification of xanthohumol C and the effect on inducing differentiation in neural precursor cells
Urmann, C; Kirchinger, M; Bieler, L; Couillard-Despres, S; Aigner, L; Riepl, H
PLANTA MED. 2015; 81(16): 1417-1418.
Abstracts (Zeitschrift)

Nichtpublizierte (nicht zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Rejuvenation of the Brain: A Pharmacological Approach
Aigner, L;
GlowBrain Final Confernce: Stem Cell and Biomaterial Applications for Brain Repair (50-80 TN); 27.-31.05.2015; Zagreb. 2015.
Brain Rejuvenation: Molecular and Cellular Targets
Aigner, L;
Billroth-Colloquium (30 TN); 25.06.2015; Salzburg. 2015.
Neuroinflammation: To Destroy or To Repair?
Aigner, L;
University of Milan; 02.-03.12.2015; Mailand. 2015.
Structural and Functional Rejuvenation of the Aged Brain by an Approved Anti-Asthmatic Drug
Aigner, L;
University of Milan; 02.-03.12.2015; Mailand. 2015.
The Role of LTCCs in Adult Neurogenesis
Aigner, L;
Annual Meeting SFB, Kloster Neustift; 09.-10.11.2015; Brixen. 2015.
Repurposing of Montelukast for Dementias
Aigner, L;
IntelgenX; 29.10.2015; Montreal. 2015.
Structural and functional rejuvenation of the aged and of the neurodegenerative brain by an approved anti­-asthmatic drug
Aigner, L;
SFN Meeting (25.000 TN); 17.10.2015; Chicago. 2015.

2014

Beiträge in Fachzeitschriften

Acute and chronic evolution of MRI findings in a case of posterior spinal cord ischemia.
Grassner, L; Klausner, F; Wagner, M; McCoy, M; Golaszewski, S; Leis, S; Aigner, L; Couillard-Despres, S; Trinka, E;
Spinal Cord. 2014;
Korrekturen
Acute and chronic evolution of MRI findings in a case of posterior spinal cord ischemia.
Grassner, L; Klausner, F; Wagner, M; McCoy, M; Golaszweski, S; Leis, S; Aigner, L; Couillard-Despres, S; Trinka, E;
Spinal Cord. 2014; 52 Suppl 1: S23-S24.
Fallberichte
Cerebrolysin protects PC12 cells from CoCl2-induced hypoxia employing GSK3β signaling.
Hartwig, K; Fackler, V; Jaksch-Bogensperger, H; Winter, S; Furtner, T; Couillard-Despres, S; Meier, D; Moessler, H; Aigner, L;
Int J Dev Neurosci. 2014; 38:52-58
Originalarbeiten (Zeitschrift)
The Maternal Brain: An Organ with Peripartal Plasticity.
Hillerer, KM; Jacobs, VR; Fischer, T; Aigner, L;
Neural Plast. 2014; 2014: 574159
Originalarbeiten (Zeitschrift)
Lactation-induced reduction in hippocampal neurogenesis is reversed by repeated stress exposure.
Hillerer, KM; Neumann, ID; Couillard-Despres, S; Aigner, L; Slattery, DA;
Hippocampus. 2014; 24(6):673-683
Originalarbeiten (Zeitschrift)
Intrinsically Active and Pacemaker Neurons in Pluripotent Stem Cell-Derived Neuronal Populations
Illes, S; Jakab, M; Beyer, F; Gelfert, R; Couillard-Despres, S; Schnitzler, A; Ritter, M; Aigner, L
STEM CELL REP. 2014; 2(3): 323-336.
Originalarbeiten (Zeitschrift)
TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons.
Kandasamy, M; Lehner, B; Kraus, S; Sander, PR; Marschallinger, J; Rivera, FJ; Trümbach, D; Ueberham, U; Reitsamer, HA; Strauss, O; Bogdahn, U; Couillard-Despres, S; Aigner, L;
J Cell Mol Med. 2014; 18(7):1444-1459
Originalarbeiten (Zeitschrift)
Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis.
Marschallinger, J; Krampert, M; Couillard-Despres, S; Heuchel, R; Bogdahn, U; Aigner, L;
Exp Gerontol. 2014; 57: 149-154.
Originalarbeiten (Zeitschrift)
Hippocampal Neurogenesis and Antidepressive Therapy: Shocking Relations
Rotheneichner, P; Lange, S; O'Sullivan, A; Marschallinger, J; Zaunmair, P; Geretsegger, C; Aigner, L; Couillard-Despres, S
NEURAL PLAST. 2014; 2014: 723915
Übersichtsarbeiten
Rat choroidal pericytes as a target of the autonomic nervous system.
Schrödl, F; Trost, A; Strohmaier, C; Bogner, B; Runge, C; Kaser-Eichberger, A; Couillard-Despres, S; Aigner, L; Reitsamer, HA;
Cell Tissue Res. 2014; 356(1):1-8
Originalarbeiten (Zeitschrift)
Characterization of dsRed2-positive cells in the doublecortin-dsRed2 transgenic adult rat retina.
Trost, A; Schroedl, F; Marschallinger, J; Rivera, FJ; Bogner, B; Runge, C; Couillard-Despres, S; Aigner, L; Reitsamer, HA;
Histochem Cell Biol. 2014; 142(6):60-17
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Prenylflavonoids from hops induce neural differentiation independent from an estrogen-like activity
Urmann, C; Oberbauer, E; Aigner, L; Riepl, H
PLANTA MED. 2014; 80(16): 1523-1523.
Abstracts (Zeitschrift)

2013

Beiträge in Fachzeitschriften

Sex-dependent regulation of hippocampal neurogenesis under basal and chronic stress conditions in rats.
Hillerer, KM; Neumann, ID; Couillard-Despres, S; Aigner, L; Slattery, DA;
Hippocampus. 2013; 23(6):476-487
Originalarbeiten (Zeitschrift)
Mesenchymal stem cell conditioning promotes rat oligodendroglial cell maturation.
Jadasz, JJ; Kremer, D; Göttle, P; Tzekova, N; Domke, J; Rivera, FJ; Adjaye, J; Hartung, HP; Aigner, L; Küry, P;
PLoS One. 2013; 8(8):e71814
Originalarbeiten (Zeitschrift)
LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro.
Jiang, L; Brackeva, B; Stangé, G; Verhaeghen, K; Costa, O; Couillard-Després, S; Rotheneichner, P; Aigner, L; Van Schravendijk, C; Pipeleers, D; Ling, Z; Gorus, F; Martens, GA;
J Proteomics. 2013; 80:26-80
Originalarbeiten (Zeitschrift)
Transforming growth factor-β1 primes proliferating adult neural progenitor cells to electrophysiological functionality.
Kraus, S; Lehner, B; Reichhart, N; Couillard-Despres, S; Wagner, K; Bogdahn, U; Aigner, L; Strauß, O;
Glia. 2013; 61(11):1767-1783
Originalarbeiten (Zeitschrift)
Brain pericyte plasticity as a potential drug target in CNS repair.
Lange, S; Trost, A; Tempfer, H; Bauer, HC; Bauer, H; Rohde, E; Reitsamer, HA; Franklin, RJ; Aigner, L; Rivera, FJ;
Drug Discov Today. 2013; 18(9-10):456-463
Übersichtsarbeiten
Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective.
Oberbauer, E; Urmann, C; Steffenhagen, C; Bieler, L; Brunner, D; Furtner, T; Humpel, C; Bäumer, B; Bandtlow, C; Couillard-Despres, S; Rivera, FJ; Riepl, H; Aigner, L;
J Nutr Biochem. 2013; 24(11):1953-1962
Originalarbeiten (Zeitschrift)
Neurogenesis and neuronal regeneration in status epilepticus.
Rotheneichner, P; Marschallinger, J; Couillard-Despres, S; Aigner, L;
Epilepsia. 2013; 54 Suppl 6:40-42
Übersichtsarbeiten
Stem cell metabolic and spectroscopic profiling.
Sander, PR; Hau, P; Koch, S; Schutze, K; Bogdahn, U; Kalbitzer, HR; Aigner, L
Trends Biotechnol. 2013; 31(3):204-213
Übersichtsarbeiten
Bone morphogenetic proteins prevent bone marrow stromal cell-mediated oligodendroglial differentiation of transplanted adult neural progenitor cells in the injured spinal cord.
Sandner, B; Rivera, FJ; Caioni, M; Nicholson, L; Eckstein, V; Bogdahn, U; Aigner, L; Blesch, A; Weidner, N;
Stem Cell Res. 2013; 11(2):758-771
Originalarbeiten (Zeitschrift)
Neural crest origin of retinal and choroidal pericytes.
Trost, A; Schroedl, F; Lange, S; Rivera, FJ; Tempfer, H; Korntner, S; Stolt, CC; Wegner, M; Bogner, B; Kaser-Eichberger, A; Krefft, K; Runge, C; Aigner, L; Reitsamer, HA;
Invest Ophthalmol Vis Sci. 2013; 54(13):7910-7921
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

MESENCHYMAL STEM CELL CONDITIONING PROMOTES OLIGODENDROGLIAL MATURATION
Jadasz, J; Kremer, D; Gottle, P; Tzekova, N; Rivera, FJ; Hartung, HP; Aigner, L; Kury, P
GLIA. 2013; 61: S147-S147.
Abstracts (Zeitschrift)
THE OLIGODENDROGENIC ACTIVITY OF BRAIN PERICYTES: A NOVEL PLAYER DURING MYELIN REPAIR?
Lange, S; Rotheneichner, P; van Wijngaarden, P; Gonzalez, G; De La Fuente, AG; Zhao, C; Franklin, RJM; Aigner, L; Rivera, FJ
GLIA. 2013; 61: S191-S191.
Abstracts (Zeitschrift)
Human platelet lysate and exosomes improve the in vitro osteogenic pre-differentiation of bone marrow-derived stem cells
Lener, T; Oeller, M; Peckl-Schmid, D; Streif, D; Gimona, M; Rivera, F; Aigner, L; Rohde, E
BONE MARROW TRANSPL. 2013; 48: S78-S78.
Abstracts (Zeitschrift)
MESENCHYMAL STEM CELLS RETAIN THEIR PRO-OLIGODENDROGENIC ACTIVITY DURING AGING: A RATIONALE FOR AUTOLOGOUS TRANSPLANTATION IN MULTIPLE SCLEROSIS
Rivera, FJ; Wodnar, R; Feichtner, M; Oberbauer, E; Brachtl, G; Greil, R; Rohde, E; Franklin, RJM; Aigner, L
GLIA. 2013; 61: S52-S52.
Abstracts (Zeitschrift)
New approach to large scale isolation of rare prenylflavonoids
Urmann, C; Oberbauer, E; Aigner, L; Riepl, H
PLANTA MED. 2013; 79(13): 1222-1222.
Abstracts (Zeitschrift)
Neurogenesis-inducing flavonoids: A structure-activity study
Urmann, C; Oberbauer, E; Aigner, L; Riepl, H
PLANTA MED. 2013; 79(13): 1120-1120.
Abstracts (Zeitschrift)

2012

Beiträge in Fachzeitschriften

Gene Expression Profiling of Neural Stem Cells and Their Neuronal Progeny Reveals IGF2 as a Regulator of Adult Hippocampal Neurogenesis
Bracko, O; Singer, T; Aigner, S; Knobloch, M; Winner, B; Ray, J; Clemenson, GD; Suh, H; Couillard-Despres, S; Aigner, L; Gage, FH; Jessberger, S
J NEUROSCI. 2012; 32(10): 3376-3387.
Originalarbeiten (Zeitschrift)
Noninvasive molecular imaging of neuroinflammation.
Jacobs, AH; Tavitian, B;
J Cereb Blood Flow Metab. 2012; 32(7):1393-1415
Übersichtsarbeiten
The remyelination Philosopher"s Stone: stem and progenitor cell therapies for multiple sclerosis.
Jadasz, JJ; Aigner, L; Rivera, FJ; Küry, P;
Cell Tissue Res. 2012; 349(1):331-347
Übersichtsarbeiten
p57kip2 regulates glial fate decision in adult neural stem cells.
Jadasz, JJ; Rivera, FJ; Taubert, A; Kandasamy, M; Sandner, B; Weidner, N; Aktas, O; Hartung, HP; Aigner, L; Küry, P;
Development. 2012; 139(18):3306-3315
Originalarbeiten (Zeitschrift)
Tendons from non-diabetic humans and rats harbor a population of insulin-producing, pancreatic beta cell-like cells.
Lehner, C; Gehwolf, R; Wagner, A; Resch, H; Hirzinger, C; Augat, P; Stephan, D; Aigner, L; Rivera, FJ; Bauer, HC; Tempfer, H;
Horm Metab Res. 2012; 44(7):506-510
Originalarbeiten (Zeitschrift)
SoxC Transcription Factors Are Required for Neuronal Differentiation in Adult Hippocampal Neurogenesis
Mu, LF; Berti, L; Masserdotti, G; Covic, M; Michaelidis, TM; Doberauer, K; Merz, K; Rehfeld, F; Haslinger, A; Wegner, M; Sock, E; Lefebvre, V; Couillard-Despres, S; Aigner, L; Berninger, B; Lie, DC
J NEUROSCI. 2012; 32(9): 3067-3080.
Originalarbeiten (Zeitschrift)
Adult mesenchymal stem cell therapy for myelin repair in multiple sclerosis.
Rivera, FJ; Aigner, L;
Biol Res. 2012; 45(3):257-268
Übersichtsarbeiten
Anxiety- rather than depression-like behavior is associated with adult neurogenesis in a female mouse model of higher trait anxiety- and comorbid depression-like behavior.
Sah, A; Schmuckermair, C; Sartori, SB; Gaburro, S; Kandasamy, M; Irschick, R; Klimaschewski, L; Landgraf, R; Aigner, L; Singewald, N
Transl Psychiatry. 2012; 2:e171
Originalarbeiten (Zeitschrift)
Neural stem cells for spinal cord repair.
Sandner, B; Prang, P; Rivera, FJ; Aigner, L; Blesch, A; Weidner, N;
Cell Tissue Res. 2012; 349(1):349-362
Übersichtsarbeiten
Mesenchymal stem cells prime proliferating adult neural progenitors toward an oligodendrocyte fate.
Steffenhagen, C; Dechant, FX; Oberbauer, E; Furtner, T; Weidner, N; Küry, P; Aigner, L; Rivera, FJ;
Stem Cells Dev. 2012; 21(11):1838-1851
Originalarbeiten (Zeitschrift)
In situ labeling and imaging of endogenous neural stem cell proliferation and migration.
Vande Velde, G; Couillard-Després, S; Aigner, L; Himmelreich, U; van der Linden, A;
WIRES NANOMED NANOBI. 2012; 4(6): 663-679.
Übersichtsarbeiten

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Characterization of adult neurogenesis in a transgenic mouse model of multiple system atrophy
Fuchs, P; Aigner, L; Poewe, W; Wenning, GK; Stefanova, N
MOVEMENT DISORD. 2012; 27: S480-S481.
Abstracts (Zeitschrift)

2011

Beiträge in Fachzeitschriften

In vivo imaging of adult neurogenesis
Couillard-Despres, S; Aigner, L
EUR J NEUROSCI. 2011; 33(6): 1037-1044.
Originalarbeiten (Zeitschrift)
Neurogenesis, Cellular Plasticity and Cognition: The Impact of Stem Cells in the Adult and Aging Brain - A Mini-Review
Couillard-Despres, S; Iglseder, B; Aigner, L
GERONTOLOGY. 2011; 57(6): 559-564.
Übersichtsarbeiten
In vivo monitoring of adult neurogenesis in health and disease.
Couillard-Despres, S; Vreys, R; Aigner, L; Van der Linden, A;
Front Neurosci. 2011; 5: 67
Übersichtsarbeiten
Inhibition of leukotriene receptors boosts neural progenitor proliferation.
Huber, C; Marschallinger, J; Tempfer, H; Furtner, T; Couillard-Despres, S; Bauer, HC; Rivera, FJ; Aigner, L;
Cell Physiol Biochem. 2011; 28(5):793-804
Originalarbeiten (Zeitschrift)
The dark side of BrdU in neural stem cell biology: detrimental effects on cell cycle, differentiation and survival.
Lehner, B; Sandner, B; Marschallinger, J; Lehner, C; Furtner, T; Couillard-Despres, S; Rivera, FJ; Brockhoff, G; Bauer, HC; Weidner, N; Aigner, L;
Cell Tissue Res. 2011; 345(3):313-328
Originalarbeiten (Zeitschrift)
H-1-Nuclear Magnetic Resonance Spectroscopy of Glioblastoma Cancer Stem Cells
Ramm, P; Bettscheider, M; Beier, D; Kalbitzer, HR; Kremer, W; Bogdahn, U; Hau, P; Aigner, L; Beier, CP
STEM CELLS DEV. 2011; 20(12): 2189-2195.
Originalarbeiten (Zeitschrift)
Remyelination in Multiple Sclerosis: The Therapeutic Potential of Neural and Mesenchymal Stem/Progenitor Cells
Rivera, FJ; Kraus, J; Steffenhagen, C; Kury, P; Weidner, N; Aigner, L
CURR SIGNAL TRANSD T. 2011; 6(3): 293-313.
Übersichtsarbeiten
Identity, fate and potential of cells grown as neurospheres: species matters.
Steffenhagen, C; Kraus, S; Dechant, FX; Kandasamy, M; Lehner, B; Poehler, AM; Furtner, T; Siebzehnrubl, FA; Couillard-Despres, S; Strauss, O; Aigner, L; Rivera, FJ;
Stem Cell Rev. 2011; 7(4):81-35
Originalarbeiten (Zeitschrift)
The ageing systemic milieu negatively regulates neurogenesis and cognitive function
Villeda, SA; Luo, J; Mosher, KI; Zou, BD; Britschgi, M; Bieri, G; Stan, TM; Fainberg, N; Ding, ZQ; Eggel, A; Lucin, KM; Czirr, E; Park, JS; Couillard-Despres, S; Aigner, L; Li, G; Peskind, ER; Kaye, JA; Quinn, JF; Galasko, DR; Xie, XMS; Rando, TA; Wyss-Coray, T
NATURE. 2011; 477(7362): 90-U157.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Differentiation Effects of Prenylflavanones and Chalcones present in Hops in Neuronal Tissue Cultures
Urmann, C; Oberbauer, E; Aigner, L; Riepl, H
PLANTA MED. 2011; 77(12): 1256-1256.
Abstracts (Zeitschrift)

2010

Beiträge in Fachzeitschriften

Stem cell quiescence in the hippocampal neurogenic niche is associated with elevated transforming growth factor-beta signaling in an animal model of Huntington disease.
Kandasamy, M; Couillard-Despres, S; Raber, KA; Stephan, M; Lehner, B; Winner, B; Kohl, Z; Rivera, FJ; Nguyen, HP; Riess, O; Bogdahn, U; Winkler, J; von Hörsten, S; Aigner, L;
J Neuropathol Exp Neurol. 2010; 69(7):717-728
Originalarbeiten (Zeitschrift)
Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntingtonxxxs disease
Kohl, Z; Regensburger, M; Aigner, R; Kandasamy, M; Winner, B; Aigner, L; Winkler, J
BMC NEUROSCI. 2010; 11:
Originalarbeiten (Zeitschrift)
Smad7 Regulates the Adult Neural Stem/Progenitor Cell Pool in a Transforming Growth Factor beta- and Bone Morphogenetic Protein-Independent Manner
Krampert, M; Chirasani, SR; Wachs, FP; Aigner, R; Bogdahn, U; Yingling, JM; Heldin, CH; Aigner, L; Heuchel, R
MOL CELL BIOL. 2010; 30(14): 3685-3694.
Originalarbeiten (Zeitschrift)
Deciphering the oligodendrogenic program of neural progenitors: cell intrinsic and extrinsic regulators.
Rivera, FJ; Steffenhagen, C; Kremer, D; Kandasamy, M; Sandner, B; Couillard-Despres, S; Weidner, N; Küry, P; Aigner, L;
Stem Cells Dev. 2010; 19(5):595-606
Übersichtsarbeiten
A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons.
Zhang, J; Giesert, F; Kloos, K; Vogt Weisenhorn, DM; Aigner, L; Wurst, W; Couillard-Despres, S;
BMC Neurosci. 2010; 11:158
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

HIGH-RESOLUTION NMR SPECTROSCOPY OF GLIOBLASTOMA-INITIATING CELLS
Ramm, P; Vollmann-Zwerenz, A; Beier, C; Aigner, L; Bogdahn, U; Kalbitzer, HR; Hau, P
NEURO-ONCOLOGY. 2010; 12: 123-123.
Abstracts (Zeitschrift)
HIGH-RESOLUTION NMR SPECTROSCOPY OF BRAIN-DERIVED STEM CELLS
Ramm, P; Vollmann-Zwerenz, A; Kumar, P; Aigner, L; Bogdahn, U; Kalbitzer, H; Hau, P
NEURO-ONCOLOGY. 2010; 12: 30-30.
Abstracts (Zeitschrift)

2009

Beiträge in Fachzeitschriften

Ageing abolishes the effects of fluoxetine on neurogenesis.
Couillard-Despres, S; Wuertinger, C; Kandasamy, M; Caioni, M; Stadler, K; Aigner, R; Bogdahn, U; Aigner, L;
MOL PSYCHIATR. 2009; 14(9): 85-64.
Originalarbeiten (Zeitschrift)
A nuclear magnetic resonance biomarker for neural progenitor cells: is it all neurogenesis?
Ramm, P; Couillard-Despres, S; Plötz, S; Rivera, FJ; Krampert, M; Lehner, B; Kremer, W; Bogdahn, U; Kalbitzer, HR; Aigner, L;
Stem Cells. 2009; 27(2):420-423
Originalarbeiten (Zeitschrift)
Mesenchymal stem cells promote oligodendroglial differentiation in hippocampal slice cultures.
Rivera, FJ; Siebzehnrubl, FA; Kandasamy, M; Couillard-Despres, S; Caioni, M; Poehler, AM; Berninger, B; Sandner, B; Bogdahn, U; Goetz, M; Bluemcke, I; Weidner, N; Aigner, L;
Cell Physiol Biochem. 2009; 24(3-4):317-324
Originalarbeiten (Zeitschrift)
Striatal transplantation for multiple system atrophy - Are grafts affected by alpha-synucleinopathy?
Stefanova, N; Hainzer, M; Stemberger, S; Couillard-Despres, S; Aigner, L; Poewe, W; Wenning, GK
EXP NEUROL. 2009; 219(1): 368-371.
Originalarbeiten (Zeitschrift)
Prolactin prevents chronic stress-induced decrease of adult hippocampal neurogenesis and promotes neuronal fate.
Torner, L; Karg, S; Blume, A; Kandasamy, M; Kuhn, HG; Winkler, J; Aigner, L; Neumann, ID;
J NEUROSCI. 2009; 29(6): 1826-1833.
Originalarbeiten (Zeitschrift)
Prolactin induces MAPK signaling in neural progenitors without alleviating glucocorticoid-induced inhibition of in vitro neurogenesis.
Wagner, K; Couillard-Despres, S; Lehner, B; Brockhoff, G; Rivera, FJ; Blume, A; Neumann, I; Aigner, L;
Cell Physiol Biochem. 2009; 24(5-6):397-406
Originalarbeiten (Zeitschrift)
Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model
Winner, B; Desplats, P; Hagl, C; Klucken, J; Aigner, R; Ploetz, S; Laemke, J; Karl, A; Aigner, L; Masliah, E; Buerger, E; Winkler, J
EXP NEUROL. 2009; 219(2): 543-552.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

STEM CELLS AND NEUROGENESIS IN THE ADULT BRAIN
Aigner, L;
Book of Abstracts. 2009; 107--FEPS 2009; 02.-15.11.2009; Ljubljana. (ISBN: 978-961-91250-5 )
Abstracts (Zeitschrift)
Live imaging of stroke induced neurogenesis in the mouse brain
Farr, TD; Kallur, T; Wiedermann, D; Couillard-Despres, S; Aigner, L; Hoehn, M
J CEREBR BLOOD F MET. 2009; 29: S544-S545.
Abstracts (Zeitschrift)
A novel regulator of neural stem cell determination/differentiation
Jadasz, J; Taubert, A; Rivera, FJ; Kandasamy, M; Aigner, L; Hartung, HP; Kuery, P
MULT SCLER. 2009; 15(9): S203-S203.
Abstracts (Zeitschrift)
Effects of oligodendroglial alpha-synucleinopathy on striatal grafts in a transgenic mouse model of MSA
Stefanova, N; Hainzer, M; Stemberger, S; Couillard-Despres, S; Aigner, L; Poewe, W; Wenning, GK
MOVEMENT DISORD. 2009; 24: S48-S48.
Abstracts (Zeitschrift)
Blood brain barrier integrity in a mouse model of MSA: towards mesenchymal stein cell therapy
Stemberger, S; Stefanova, N; Aigner, L; Wenning, GK
MOVEMENT DISORD. 2009; 24: S48-S48.
Abstracts (Zeitschrift)

2008

Beiträge in Fachzeitschriften

TGF-beta in neural stem cells and in tumors of the central nervous system
Aigner, L; Bogdahn, U
CELL TISSUE RES. 2008; 331(1): 225-241.
Übersichtsarbeiten
In vivo optical imaging of neurogenesis: watching new neurons in the intact brain.
Couillard-Despres, S; Finkl, R; Winner, B; Ploetz, S; Wiedermann, D; Aigner, R; Bogdahn, U; Winkler, J; Hoehn, M; Aigner, L;
Mol Imaging. 2008; 7(1): 28-34.
Originalarbeiten (Zeitschrift)
Human in vitro reporter model of neuronal development and early differentiation processes.
Couillard-Despres, S; Quehl, E; Altendorfer, K; Karl, C; Ploetz, S; Bogdahn, U; Winkler, J; Aigner, L;
BMC Neurosci. 2008; 9: 31
Originalarbeiten (Zeitschrift)
Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons.
Ladewig, J; Koch, P; Endl, E; Meiners, B; Opitz, T; Couillard-Despres, S; Aigner, L; Brüstle, O;
Stem Cells. 2008; 26(7): 1705-1712.
Originalarbeiten (Zeitschrift)
Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis.
Mueller, AM; Pedré, X; Stempfl, T; Kleiter, I; Couillard-Despres, S; Aigner, L; Giegerich, G; Steinbrecher, A;
J Neuroinflammation. 2008; 5: 20
Originalarbeiten (Zeitschrift)
Oligodendrogenesis of adult neural progenitors: differential effects of ciliary neurotrophic factor and mesenchymal stem cell derived factors.
Rivera, FJ; Kandasamy, M; Couillard-Despres, S; Caioni, M; Sanchez, R; Huber, C; Weidner, N; Bogdahn, U; Aigner, L;
J NEUROCHEM. 2008; 107(3): 832-843.
Originalarbeiten (Zeitschrift)
Dopaminergic lesion enhances growth factor-induced striatal neuroblast migration.
Winner, B; Couillard-Despres, S; Geyer, M; Aigner, R; Bogdahn, U; Aigner, L; Kuhn, HG; Winkler, J;
J Neuropathol Exp Neurol. 2008; 67(2): 105-116.
Originalarbeiten (Zeitschrift)

2007

Beiträge in Fachzeitschriften

CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles.
Beier, D; Hau, P; Proescholdt, M; Lohmeier, A; Wischhusen, J; Oefner, PJ; Aigner, L; Brawanski, A; Bogdahn, U; Beier, CP;
Cancer Res. 2007; 67(9): 4010-4015.
Originalarbeiten (Zeitschrift)
Novel POMGnT1 mutations define broader phenotypic spectrum of muscle-eye-brain disease
Hehr, U; Uyanik, G; Gross, C; Walter, MC; Bohring, A; Cohen, M; Oehl-Jaschkowitz, B; Bird, LM; Shamdeen, GM; Bogdahn, U; Schuierer, G; Topaloglu, H; Aigner, L; Lochmuller, H; Winkler, J
NEUROGENETICS. 2007; 8(4): 279-288.
Originalarbeiten (Zeitschrift)
Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington"s disease.
Kohl, Z; Kandasamy, M; Winner, B; Aigner, R; Gross, C; Couillard-Despres, S; Bogdahn, U; Aigner, L; Winkler, J;
Brain Res. 2007; 1155:24-33
Originalarbeiten (Zeitschrift)
Location and type of mutation in the LIS1 gene do not predict phenotypic severity
Uyanik, G; Morris-Rosendahl, DJ; Stiegler, J; Klapecki, J; Gross, C; Berman, Y; Martin, P; Dey, L; Spranger, S; Korenke, GC; Schreyer, I; Hertzberg, C; Neumann, TE; Burkart, P; Spaich, C; Meng, N; Holthausen, H; Ades, L; Seidel, J; Mangold, E; Buyse, G; Meinecke, P; Schara, U; Zeschnigk, C; Muller, D; Helland, G; Schulze, B; Wright, ML; Kortge-Jung, S; Hehr, A; Bogdahn, U; Schuierer, G; Kohlhase, J; Aigner, L; Wolff, G; Hehr, U; Winkler, J
NEUROLOGY. 2007; 69(5): 442-447.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Modifying neurogenesis and the intrinsic migratory competence of neurons in the adult brain
Aigner, L; Couillard-Despres, S; Winkler, J; Bogdahn, U
J NEUROCHEM. 2007; 102: 242-242.
Abstracts (Zeitschrift)
The role of dopamine in adult neurogenesis in models of Parkinson's disease
Winkler, J; Hagl, C; Karl, A; Aigner, L; Buerger, E; Winner, B
J NEURAL TRANSM. 2007; 114(3): IX-IX.
Abstracts (Zeitschrift)

2006

Beiträge in Fachzeitschriften

Targeted transgene expression in neuronal precursors: watching young neurons in the old brain.
Couillard-Despres, S; Winner, B; Karl, C; Lindemann, G; Schmid, P; Aigner, R; Laemke, J; Bogdahn, U; Winkler, J; Bischofberger, J; Aigner, L;
Eur J Neurosci. 2006; 24(6): 153-145.
Originalarbeiten (Zeitschrift)
Autologous adult rodent neural progenitor cell transplantation represents a feasible strategy to promote structural repair in the chronically injured spinal cord
Pfeifer, K; Vroemen, M; Caioni, M; Aigner, L; Bogdahn, U; Weidner, N
REGEN MED. 2006; 1(2): 255-266.
Originalarbeiten (Zeitschrift)
Mesenchymal stem cells instruct oligodendrogenic fate decision on adult neural stem cells.
Rivera, FJ; Couillard-Despres, S; Pedre, X; Ploetz, S; Caioni, M; Lois, C; Bogdahn, U; Aigner, L;
Stem Cells. 2006; 24(10):2209-2219
Originalarbeiten (Zeitschrift)
Adult hippocampus derived soluble factors induce a neuronal-like phenotype in mesenchymal stem cells.
Rivera, FJ; Sierralta, WD; Minguell, JJ; Aigner, L;
Neurosci Lett. 2006; 406(1-2):49-54
Originalarbeiten (Zeitschrift)
Transforming growth factor-beta1 is a negative modulator of adult neurogenesis.
Wachs, FP; Winner, B; Couillard-Despres, S; Schiller, T; Aigner, R; Winkler, J; Bogdahn, U; Aigner, L;
J Neuropathol Exp Neurol. 2006; 65(4):358-370
Originalarbeiten (Zeitschrift)
Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb.
Winner, B; Geyer, M; Couillard-Despres, S; Aigner, R; Bogdahn, U; Aigner, L; Kuhn, G; Winkler, J;
Exp Neurol. 2006; 197(1):113-121
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Transforming growth factor-beta1 is a negative modulator of adult neurogenesis
Aigner, L; Wachs, FP; Winner, B; Winkler, J; Bogdahn, U
NEUROLOGY. 2006; 66(5): A396-A396.
Abstracts (Zeitschrift)
CD133+ and CD133- Cancer stem cells in glioblastoma
Beier, D; Hau, P; Proescholdt, M; Lohmeier, A; Aigner, L; Brawanski, A; Bogdahn, U; Beier, CP
NEURO-ONCOLOGY. 2006; 8(4): 317-317.
Abstracts (Zeitschrift)
Lineage selection of double cortin-positive human ES cell-derived neurons: an efficient tool for purification of transplantable immature neurons
Ladewig, J; Koch, P; Meiners, B; Itskovitz-Eldor, J; Couillard-Despres, S; Aigner, L; Brustle, O
ACTA NEUROPATHOL. 2006; 112(3): 367-367.
Abstracts (Zeitschrift)
LIS1 mutations associated with different forms of neuronal migration disorders
Uyanik, G; Gross, C; Bogdahn, U; Aigner, L; Hehr, U; Winkler, J
NEUROLOGY. 2006; 66(5): A329-A329.
Abstracts (Zeitschrift)

2005

Beiträge in Fachzeitschriften

Doublecortin expression levels in adult brain reflect neurogenesis.
Couillard-Despres, S; Winner, B; Schaubeck, S; Aigner, R; Vroemen, M; Weidner, N; Bogdahn, U; Winkler, J; Kuhn, HG; Aigner, L;
Eur J Neurosci. 2005; 21(1):-14
Originalarbeiten (Zeitschrift)
Adult retinal pigment epithelium cells express neural progenitor properties and the neuronal precursor protein doublecortin
Engelhardt, M; Bogdahn, U; Aigner, L
BRAIN RES. 2005; 1040(01/02/2015): 98-111.
Originalarbeiten (Zeitschrift)
Neuronal precursor-specific activity of a human doublecortin regulatory sequence.
Karl, C; Couillard-Despres, S; Prang, P; Munding, M; Kilb, W; Brigadski, T; Plötz, S; Mages, W; Luhmann, H; Winkler, J; Bogdahn, U; Aigner, L;
J Neurochem. 2005; 92(2):264-282
Originalarbeiten (Zeitschrift)

2004

Beiträge in Fachzeitschriften

Mitotic impairment by doublecortin is diminished by doublecortin mutations found in patients.
Couillard-Despres, S; Uyanik, G; Ploetz, S; Karl, C; Koch, H; Winkler, J; Aigner, L;
Neurogenetics. 2004; 5(2): 83-93.
Originalarbeiten (Zeitschrift)
The neurogenic competence of progenitors from the postnatal rat retina in vitro.
Engelhardt, M; Wachs, FP; Couillard-Despres, S; Aigner, L;
Exp Eye Res. 2004; 78(5): 1025-1036.
Originalarbeiten (Zeitschrift)
Functional imaging in PNH caused by a new FilaminA mutation
Lange, M; Winner, B; Muller, JL; Marienhagen, J; Schroder, M; Aigner, L; Uyanik, G; Winkler, J
NEUROLOGY. 2004; 62(1): 151-152.
Editorials
Direct stimulation of adult neural stem cells in vitro and neurogenesis in vivo by vascular endothelial growth factor
Schanzer, A; Wachs, FP; Wilhelm, D; Acker, T; Cooper-Kuhn, C; Beck, H; Winkler, J; Aigner, L; Plate, KH; Kuhn, HG
BRAIN PATHOL. 2004; 14(3): 237-248.
Originalarbeiten (Zeitschrift)
Human wild-type alpha-synuclein impairs neurogenesis
Winner, B; Lie, DCH; Rockenstein, E; Aigner, R; Aigner, L; Masliah, E; Kuhn, HG; Winkler, J
J NEUROPATH EXP NEUR. 2004; 63(11): 1155-1166.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Clinical and molecular characterization of different forms of lissencephalies
Winkler, J; Hehr, U; Aigner, L; Uyanik, G
NEUROLOGY. 2004; 62(7): A19-A19.
Abstracts (Zeitschrift)

2003

Beiträge in Fachzeitschriften

Somatic mosaicism and variable penetrance in doublecortin-associated migration disorders.
Aigner, L; Uyanik, G; Couillard-Despres, S; Ploetz, S; Wolff, G; Morris-Rosendahl, D; Martin, P; Eckel, U; Spranger, S; Otte, J; Woerle, H; Holthausen, H; Apheshiotis, N; Fluegel, D; Winkler, J;
Neurology. 2003; 60(2): 329-332.
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Transient expression of doublecortin during adult neurogenesis.
Brown, JP; Couillard-Després, S; Cooper-Kuhn, CM; Winkler, J; Aigner, L; Kuhn, HG;
J Comp Neurol. 2003; 467(1): 1-10.
Originalarbeiten (Zeitschrift)
ARX mutations in X-linked lissencephaly with abnormal genitalia
Uyanik, G; Aigner, L; Martin, P; Gross, C; Neumann, D; Marschner-Schafer, H; Hehr, U; Winkler, J
NEUROLOGY. 2003; 61(2): 232-235.
Originalarbeiten (Zeitschrift)
Neuronal migration disorders: Clinic and molecular genetics of lissencephalies
Uyanik, G; Hehr, U; Aigner, L; Winkler, J
AKTUEL NEUROL. 2003; 30(7): 328-334.
Übersichtsarbeiten
Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate along axonal pathways
Vroemen, M; Aigner, L; Winkler, J; Weidner, N
EUR J NEUROSCI. 2003; 18(4): 743-751.
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High efficacy of clonal growth and expansion of adult neural stem cells.
Wachs, FP; Couillard-Despres, S; Engelhardt, M; Wilhelm, D; Ploetz, S; Vroemen, M; Kaesbauer, J; Uyanik, G; Klucken, J; Karl, C; Tebbing, J; Svendsen, C; Weidner, N; Kuhn, HG; Winkler, J; Aigner, L;
Lab Invest. 2003; 83(7):949-962
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2002

Beiträge in Fachzeitschriften

Mutational and expression analysis of the reelin pathway components CDK5 and doublecortin in gangliogliomas
Becker, AJ; Klein, H; Baden, T; Aigner, L; Normann, S; Elger, CE; Schramm, J; Wiestler, OD; Blumcke, I
ACTA NEUROPATHOL. 2002; 104(4): 403-408.
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Preweaning enrichment has no lasting effects on adult hippocampal neurogenesis in four-month-old mice
Kohl, Z; Kuhn, HG; Cooper-Kuhn, CM; Winkler, J; Aigner, L; Kempermann, G
GENES BRAIN BEHAV. 2002; 1(1): 46-54.
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Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Preservation of ganglion cells in adult retinal tissue cultures - An in vitro model for neuroprotection
Eckert, E; Kobuch, KA; Aigner, L; Spiegel, D
INVEST OPHTH VIS SCI. 2002; 43: U163-U163.
Abstracts (Zeitschrift)
Neural stem cells in the postnatal rat retina
Engelhardt, M; Aigner, L
INVEST OPHTH VIS SCI. 2002; 43: U1022-U1022.
Abstracts (Zeitschrift)
Adult neural stem cells: Improvement of culture conditions for clonal expansion
Wilhelm, D; Couillard-Despres, S; Wachs, FP; Plate, KH; Winkler, J; Kuhn, HG; Aigner, L
ACTA NEUROPATHOL. 2002; 104(5): 576-576.
Abstracts (Zeitschrift)

2001

Beiträge in Fachzeitschriften

Molecular mechanisms of neuronal migration disorders, quo vadis?
Couillard-Despres, S; Winkler, J; Uyanik, G; Aigner, L;
Curr Mol Med. 2001; 1(6): 677-688.
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Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Isolation and in-vitro conditions for adult neural stem cells
Wilhelm, D; Wachs, FP; Plate, KH; Kuhn, HG; Aigner, L
ACTA NEUROPATHOL. 2001; 102(5): 546-546.
Abstracts (Zeitschrift)

2000

Beiträge in Fachzeitschriften

Isolated lissencephaly sequence and double-cortex syndrome in a German family with a novel doublecortin mutation
Aigner, L; Fluegel, D; Dietrich, J; Ploetz, S; Winkler, J
NEUROPEDIATRICS. 2000; 31(4): 195-198.
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1999

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Neuron-glia interactions in the injured PNS and CNS
Aguayo, AJ; Aigner, L; Friedman, H; Singel, S; Bray, GM
KEIO UNIV SYMP LIFE. 1999; 2: 500-500.
Abstracts (Zeitschrift)
Protection of photoreceptors from light-damage by BDNF gene transfer to the retina
Di Polo, A; Aigner, LJ; Bray, GM; Aguayo, AJ
INVEST OPHTH VIS SCI. 1999; 40(4): S760-S760.
Abstracts (Zeitschrift)

1998

Beiträge in Fachzeitschriften

Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Muller cells temporarily rescues injured retinal ganglion cells
Di Polo, A; Aigner, LJ; Dunn, RJ; Bray, GM; Aguayo, AJ
P NATL ACAD SCI USA. 1998; 95(7): 3978-3983.
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Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Experimental manipulations of glial-neuronal interactions in the injured retina
Aguayo, AJ; DiPolo, A; Aigner, L; Friedman, H; Singel, S; Bray, GM
EUR J NEUROSCI. 1998; 10: 329-329.
Abstracts (Zeitschrift)
Viral-mediated gene transfer of BDNF to Muller glia temporarily rescues axotomized retinal ganglion cells.
Aigner, L; Di Polo, A; Dunn, RJ; Bray, GM; Aguayo, AJ
EUR J NEUROSCI. 1998; 10: 356-356.
Abstracts (Zeitschrift)

1997

Beiträge in Fachzeitschriften

Intrinsic neuronal determinants locally regulate extrasynaptic and synaptic growth at the adult neuromuscular junction
Caroni, P; Aigner, L; Schneider, C
J CELL BIOL. 1997; 136(3): 679-692.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Adenovirus-mediated gene transfer of BCNF delays the death of injured retinal ganglion cells.
DiPolo, A; Aigner, LJ; Dunn, RJ; Bray, GM; Aguayo, AJ
INVEST OPHTH VIS SCI. 1997; 38(4): 1196-1196.
Abstracts (Zeitschrift)

1995

Beiträge in Fachzeitschriften

OVEREXPRESSION OF THE NEURAL GROWTH-ASSOCIATED PROTEIN GAP-43 INDUCES NERVE SPROUTING IN THE ADULT NERVOUS-SYSTEM OF TRANSGENIC MICE
AIGNER, L; ARBER, S; KAPFHAMMER, JP; LAUX, T; SCHNEIDER, C; BOTTERI, F; BRENNER, HR; CARONI, P
CELL. 1995; 83(2): 269-278.
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ABSENCE OF PERSISTENT SPREADING, BRANCHING, AND ADHESION IN GAP-43-DEPLETED GROWTH CONES
AIGNER, L; CARONI, P
J CELL BIOL. 1995; 128(4): 647-660.
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1993

Beiträge in Fachzeitschriften

DEPLETION OF 43-KD GROWTH-ASSOCIATED PROTEIN IN PRIMARY SENSORY NEURONS LEADS TO DIMINISHED FORMATION AND SPREADING OF GROWTH CONES
AIGNER, L; CARONI, P
J CELL BIOL. 1993; 123(2): 417-429.
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1992

Beiträge in Fachzeitschriften

CONSTRUCTION OF YEAST ARTIFICIAL CHROMOSOME (YAC) CLONE BANKS COVERING 3 GENOME EQUIVALENTS AND ISOLATION OF YACS CONTAINING THE HUMAN GENE ENCODING TUMOR-NECROSIS-FACTOR RECEPTOR-BETA
DELOUKAS, P; AIGNER, L; KANIA, M; VANLOON, APGM
GENE. 1992; 110(2): 189-195.
Originalarbeiten (Zeitschrift)
PROTEIN-KINASES NEGATIVELY AFFECT NUCLEAR FACTOR-KAPPA-B ACTIVATION BY TUMOR-NECROSIS-FACTOR-ALPHA AT 2 DIFFERENT STAGES IN PROMYELOCYTIC HL-60 CELLS
HOHMANN, HP; REMY, R; AIGNER, L; BROCKHAUS, M; VANLOON, APGM
J BIOL CHEM. 1992; 267(3): 2065-2072.
Originalarbeiten (Zeitschrift)