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Forschungsdatenbank PMU-SQQUID

UNIVERSITÄTSINSTITUT FÜR PHARMAZIE:

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37 Publikationen

2019

Beiträge in Fachzeitschriften

Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy.
Ardelt, MA; Fröhlich, T; Martini, E; Müller, M; Kanitz, V; Atzberger, C; Cantonati, P; Meßner, M; Posselt, L; Lehr, T; Wojtyniak, JG; Ulrich, M; Arnold, GJ; König, L; Parazzoli, D; Zahler, S; Rothenfußer, S; Mayr, D; Gerbes, A; Scita, G; Vollmar, AM; Pachmayr, J;
Hepatology. 2019; 69(1):376-393
Originalarbeiten (Zeitschrift)
Early inhibition of endothelial retinoid uptake upon myocardial infarction restores cardiac function and prevents cell, tissue, and animal death.
Danzl, K; Messner, B; Doppler, C; Nebert, C; Abfalterer, A; Sakic, A; Temml, V; Heinz, K; Streitwieser, R; Edelmann, T; Mairhofer, M; Grimm, M; Laufer, G; Zierer, A; Stuppner, H; Schuster, D; Ploner, C; Müller, T; Bernhard, D;
J Mol Cell Cardiol. 2019; 126:105-117
Originalarbeiten (Zeitschrift)
Parallel in vitro and in silico investigations into anti-inflammatory effects of non-prenylated stilbenoids.
Lelakova, V; Smejkal, K; Jakubczyk, K; Vesely, O; Landa, P; Vaclavik, J; Bobal, P; Pizova, H; Temml, V; Steinacher, T; Schuster, D; Granica, S; Hanakova, Z; Hosek, J
Food Chem. 2019; 285:431-440
Originalarbeiten (Zeitschrift)
Mushroom Tyrosinase-Based Enzyme Inhibition Assays Are Not Suitable for Bioactivity-Guided Fractionation of Extracts
Mayr, F; Sturm, S; Ganzera, M; Waltenberger, B; Martens, S; Schwaiger, S; Schuster, D; Stuppner, H
J NAT PROD. 2019; 82(1): 136-147.
Originalarbeiten (Zeitschrift)
Synthesis, Biological Evaluation and Structure-Activity Relationships of Diflapolin Analogues as Dual sEH/FLAP Inhibitors
Vieider, L; Romp, E; Temml, V; Fischer, J; Kretzer, C; Schoenthaler, M; Taha, A; Hernandez-Olmos, V; Sturm, S; Schuster, D; Werz, O; Garscha, U; Matuszczak, B
ACS MED CHEM LETT. 2019; 10(1): 62-66.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Identification of the fungicide epoxiconazole as inhibitor of human 11ß-hydroxylase and aldosterone synthase.
Akram, M; Patt, M; Kaserer, T; Temml, V; Waratchareeyakul, W; Kratschmar, DV; Haupenthal, J; Hartmann, RW; Odermatt, A; Schuster, D;
10. Paracelsus Science Get Together Abstractband 2019.. 2019; -10. Paracelsus Science Get Together; 28.06.2019; Nürnberg.
Abstracts (Zeitschrift)
Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11ß-hydroxylase and aldosterone synthase
Akram, M; Patt, M; Kaserer, T; Temml, V; Waratchareeyakul, W; Kratschmar, DV; Haupenthal, J; Hartmann, RW; Odermatt, A; Schuster, D;
Final Programme & Book of Abstracts. 2019; -26th Scientific Congress of the Austrian Pharmaceutical Society ; 25.-27.04.2019; Graz.
Abstracts (Zeitschrift)
Cdk5 Inhibition - The Key to Enhancing the Standard of Care in Hepatocellular Carcinoma Treatment.
Ardelt, MA; Fröhlich, T; Martini, E; Müller, M; Kanitz, V; Atzberger, C; Cantonati, P; Meßner, M; Posselt, L; Lehr, T; Wojtyniak, JG; Ulrich, M; Arnold, GJ; König, L; Parazzoli, D; Zahler, S; Rothenfußer, S; Mayr, D; Gerbes, A; Scita, G; Vollmar, AM; Pachmayr, J;
Final Programme & Book of Abstracts.. 2019; -26th Scientific Congress of the Austrian Pharmaceutical Society ; 25.-27.04.2019; Graz.
Abstracts (Zeitschrift)
Potential to improve the therapeutic situation of HCC patients - The influence of Regorafenib and Lenvatinib treatment in combination with Cdk5 inhibition in HCC.
Ardelt, MA; Huber-Cantonati, P; Pachmayr, J;
Final Programme & Book of Abstracts.. 2019; -26th Scientific Congress of the Austrian Pharmaceutical Society; 25.-27.04.2019; Graz.
Abstracts (Zeitschrift)
Potential to improve the therapeutic situation of HCC patients - The influence of Regorafenib and Lenvatinib treatment in combination with Cdk5 inhibition in HCC.
Ardelt, MA; Huber-Cantonati, P; Pachmayr, J;
10. Paracelsus Science Get Together Abstractband 2019. 2019; -10. Paracelsus Science Get Together ; 28.06.2019; Nürnberg.
Abstracts (Zeitschrift)
Diamonds in the rough - With low application Antibiotics against Tumor Relapse of sorafenib-resistant Hepatocellular Carcinoma.
Meßner, M; Zischka, H; Schmitt, S; Ardelt, MA; Huber-Cantonati, P; Fröhlich, T; Arnold, GJ; Atzberger, C; Müller, M; Pein, H; Koeberle, A; Zobel, LM; Koenig, L; Vollmair, AM; Pachmayr, J;
Final Programme & Book of Abstracts.. 2019; -26th Scientific Congress of the Austrian Pharmaceutical Society ; 25.-27.04.2019; Graz.
Abstracts (Zeitschrift)
Comparison of the 3D structures of ß-Adrenergic Receptors and the Binding Modes of Agonists
Ujiantari, NSO; Schuster, D;
Finale Programm & Book of Abstracts. 2019; -26th Scientific Congress of the Austrian Pharmaceutical Society ; 25.-27.04.2019; Graz.
Abstracts (Zeitschrift)

Originalbeiträge in Sammelwerk (Buchbeitrag)

Fingerprints and Pharmacophores.
Schuster, D;
In: Ranganathan, S; Gribskov, M; Nakai, K; Schönbach Ch (Eds.); editors(s). Encyclopedia of Bioinformatics and Computational Biology.. 2: Elsevier; p. 619-627. (ISBN: 978-0-12-811432-2)

2018

Beiträge in Fachzeitschriften

Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E
Cheung, SY; Werner, M; Esposito, L; Troisi, F; Cantone, V; Liening, S; König, S; Gerstmeier, J; Koeberle, A; Bilancia, R; Rizza, R; Rossi, A; Roviezzo, F; Temml, V; Schuster, D; Stuppner, H; Schubert-Zsilavecz, M; Werz, O; Hanke, T; Pace, S;
Eur J Med Chem. 2018; 156: 815-830.
Originalarbeiten (Zeitschrift)
Magnolol dimer-derived fragments as PPARγ-selective probes.
Dreier, D; Resetar, M; Temml, V; Rycek, L; Kratena, N; Schnürch, M; Schuster, D; Dirsch, VM; Mihovilovic, MD;
Org Biomol Chem. 2018; 16(38): 7019-7028.
Originalarbeiten (Zeitschrift)
Design and synthesis of tailored human caseinolytic protease P inhibitors.
Gronauer, TF; Mandl, MM; Lakemeyer, M; Hackl, MW; Messner, M; Korotkov, VS; Pachmayr, J; Sieber, SA
CHEM COMMUN. 2018; 54(70): 9833-9836.
Originalarbeiten (Zeitschrift)
3D printing of oral drugs: a new reality or hype?
Hsiao, WK; Lorber, B; Reitsamer, H; Khinast, J
EXPERT OPIN DRUG DEL. 2018; 15(1): 1-4.
Editorials
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.
Pein, H; Ville, A; Pace, S; Temml, V; Garscha, U; Raasch, M; Alsabil, K; Viault, G; Dinh, CP; Guilet, D; Troisi, F; Neukirch, K; Konig, S; Bilancia, R; Waltenberger, B; Stuppner, H; Wallert, M; Lorkowski, S; Weinigel, C; Rummler, S; Birringer, M; Roviezzo, F; Sautebin, L; Helesbeux, JJ; Seraphin, D; Mosig, AS; Schuster, D; Rossi, A; Richomme, P; Werz, O; Koeberle, A
NAT COMMUN. 2018; 9(1): 3834
Originalarbeiten (Zeitschrift)
Dihydrochalcone Glucosides from the Subaerial Parts of Thonningia sanguinea and Their in Vitro PTP1B Inhibitory Activities.
Pompermaier, L; Heiss, EH; Alilou, M; Mayr, F; Monizi, M; Lautenschlaeger, T; Schuster, D; Schwaiger, S; Stuppner, H;
J Nat Prod. 2018; 81(9): 209-2100.
Originalarbeiten (Zeitschrift)
Stereoselective Synthesis of the Isomers of Notoincisol A: Assigment of the Absolute Configuration of this Natural Product and Biological Evaluation.
Rycek, L; Ticli, V; Pyszkowski, J; Latkolik, S; Liu, X; Atanasov, AG; Steinacher, T; Bauer, R; Schuster, D; Dirsch, VM; Schnurch, M; Ernst, M; Mihovilovic, MD
J NAT PROD. 2018; 81(11): 2419-2428.
Originalarbeiten (Zeitschrift)
Pharmacophore-based discovery of 2-(phenylamino)aceto-hydrazides as potent eosinophil peroxidase (EPO) inhibitors.
Schuster, D; Zederbauer, M; Langer, T; Kubin, A; Furtmüller, PG;
J Enzyme Inhib Med Chem. 2018; 33(1): 1529-1536.
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

The anti-fungal epoxiconazole inhibits human CYP P450 11B1 and CYP P450 11B2: Virtual screening as a tool to find potential endocrine disruptors.
Akram, M; Patt, M; Kaserer, T; Temml, V; Waratchareeyakul, W; Haupenthal, J; Hartmann, RW; Odermatt, A; Schuster, D;
Paracelsus Science Get Together Abstractband 2018.. 2018; 31-31.-Paracelsus Science Get Together 2018; 29.6.2018; Paracelsus Medizinische Privatuniversität Salzburg. (ISBN: 978-3-200-05737-1 )
Abstracts (Zeitschrift)
Inhibition of Cdk5 - Introducing New Strategies to Prevent Sorafenib Treatment Escape in HCC Cells.
Ardelt, MA; Fröhlich, T, Martini, E; Müller, M; Kanitz, V; Atzberger, C; Posselt, L; Lehr, T; Wojtyniak, JG; Ulrich, M; Arnold, GJ; König, L; Parazzoli, D; Zahler, S; Rothenfußer, S; Mayr, D; Gerbes, A; Scita, G; Vollmar, AM; Pachmayr, J;
Paracelsus Science Get Together Abstractband 2018.. 2018; 98-98.-Paracelsus Science Get Together 2018; 29.6.2018; Paracelsus Medizinische Privatuniversität Salzburg. (ISBN: 978-3-200-05737-1 )
Abstracts (Zeitschrift)
Computational and in vitro screening identify vitamins and fatty acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.
Herdlinger, SC; Baumgartner, RR; Steindl, TM; Rollinger, JM; Atanasov, AG; Heiss, EH; Dirsch, VM; Schuster, D;
Paracelsus Science Get Together Abstractband 2018.. 2018; 116-116.-Paracelsus Science Get Together 2018; 29.6.2018; Paracelsus Medizinische Privatuniversität Salzburg. (ISBN: 978-3-200-05737-1 )
Abstracts (Zeitschrift)
Drug repositioning of 10 dihydrochalcones from Malus-leaves using a combined in-silico method.
Mayr, F; Möller, G; Martens, S; Schwaiger, S; Waltenberger, B; Adamski, J; Stuppner, H; Schuster, D;
Paracelsus Science Get Together Abstractband 2018.. 2018; 138-138.-Paracelsus Science Get Together 2018; 29.6.2018; Paracelsus Medizinische Privatuniverisität Salzburg. (ISBN: 978-3-200-05737-1 )
Abstracts (Zeitschrift)
Epithelial-to-mesenchymal transition and evasive PI3K/Akt pathway activation contribute to Sorafenib-resistance of Hepatocellular Carcinoma.
Meßner, M; Ardelt, MA; Fröhlich, T; Arnold, GJ; Vollmar, AM; Pachmayr, J;
Paracelsus Science Get Together Abstractband 2018.. 2018; 175-175.-Paracelsus Science Get Together 2018; 29.6.2018; Paracelsus Medizinische Privatuniversität Salzburg. (ISBN: 978-3-200-05737-1 )
Abstracts (Zeitschrift)
Computational analysis of the interaction between vitamin E derivatives and 5-lipoxygenase.
Temml, V; Pein, H; Pace, S; Garscha, U; Waltenberger, B; Stuppner, H; Roviezzo, F; Helesbeux, JJ; Séraphin, D; Rossi, A; Richomme, P; Werz, O; Koeberle, O; Schuster, D;
Paracelsus Science Get Together Abstractband 2018.. 2018; 23-23.-Paracelsus Science Get Together 2018; 29.6.2018; Paracelsus Medizinische Privatuniversität Salzburg. (ISBN: 978-3-200-05737-1 )
Abstracts (Zeitschrift)
Homology Modeling of ß1 Adrenergic Receptor.
Ujiantari, O; Schuster, D;
Paracelus Science Get Together Abstractband 2018.. 2018; 154-154.-Paracelsus Science Get Together 2018; 29.6.2018; Paracelsus Medizinische Privatuniversität Salzburg. (ISBN: 978-3-200-05737-1 )
Abstracts (Zeitschrift)
Development and validation of pharmacophore models for human cytochrome P450 11 B1 and P450 11B2 inhibition.
Waratchareeyakul, W; Akram, M; Haupenthal, J; Hartmann, RW; Schuster, D;
Paracelsus Science Get Together Abstractband 2018.. 2018; 163-163.-Paracelsus Science Get Together 2018; 29.6.2018; Paracelsus Medizinische Privatuniverstität Salzburg. (ISBN: 978-3-200-05737-1 )
Abstracts (Zeitschrift)

Originalbeiträge in Sammelwerk (Buchbeitrag)

Computational Studies on Natural Products for the Development of Multi-target Drugs
Temml, V; Schuster D;
In: Kunal Roy (Ed.) editors(s). Multi-Target Drug Design Using Chem-Bioinformatic Approaches.. New York, NY: Humana Press; p. 187-201 . (ISBN: 978-1-4939-8732-0)

2017

Beiträge in Fachzeitschriften

Inhibition of the V-ATPase by Archazolid A: A New Strategy to Inhibit EMT
Merk, H; Messer, P; Ardelt, MA; Lamb, DC; Zahler, S; Muller, R; Vollmar, AM; Pachmayr, J
MOL CANCER THER. 2017; 16(11): 2329-2339.
Originalarbeiten (Zeitschrift)
Importance of 5/6-aryl substitution on the pharmacological profile of 4"-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1"-biphenyl]-2-carboxylic acid derived PPARγ agonists.
Obermoser, V; Mauersberger, R; Schuster, D; Czifersky, M; Lipova, M; Siegl, M; Kintscher, U; Gust, R
Eur J Med Chem. 2017; 126:590-603
Originalarbeiten (Zeitschrift)
Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase.
Peduto, A; Scuotto, M; Krauth, V; Roviezzo, F; Rossi, A; Temml, V; Esposito, V; Stuppner, H; Schuster, D; DxxxAgostino, B; Schiraldi, C; de Rosa, M; Werz, O; Filosa, R
Eur J Med Chem. 2017; 127:715-726
Originalarbeiten (Zeitschrift)
Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening.
Temml, V; Garscha, U; Romp, E; Schubert, G; Gerstmeier, J; Kutil, Z; Matuszczak, B; Waltenberger, B; Stuppner, H; Werz, O; Schuster, D
Sci Rep. 2017; 7:42751
Originalarbeiten (Zeitschrift)
Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.
Vuorinen, A; Engeli, RT; Leugger, S; Bachmann, F; Akram, M; Atanasov, AG; Waltenberger, B; Temml, V; Stuppner, H; Krenn, L; Ateba, SB; Njamen, D; Davis, RA; Odermatt, A; Schuster, D
J Nat Prod. 2017; 80(4):965-974
Originalarbeiten (Zeitschrift)
Phenylbenzenesulfonates and -sulfonamides as 17β-hydroxysteroid dehydrogenase type 2 inhibitors: Synthesis and SAR-analysis.
Vuorinen, A; Engeli, RT; Leugger, S; Kreutz, CR; Schuster, D; Odermatt, A; Matuszczak, B
Bioorg Med Chem Lett. 2017; 27(13):2982-2985
Originalarbeiten (Zeitschrift)

Publizierte (zitierfähige) Beiträge für wissenschaftliche Veranstaltungen

Cyclin-dependent Kinase 5 Inhibits Osteoblast Differentiation to Regulate Bone Integrity.
Ahmad, M; Vettorazzi, S; Vazquez, DC; Lai, D; Kroll, T; Vuijc-Spasic, M; Ploubidou, A; Pachmayr, J; Tuckermann, J
J BONE MINER RES. 2017; 32: S179-S179.
Abstracts (Zeitschrift)